| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10027680m |
| Family | GT47 |
| Protein Properties | Length: 657 Molecular Weight: 75805.3 Isoelectric Point: 8.5307 |
| Chromosome | Chromosome/Scaffold: 14 Start: 2819016 End: 2821101 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 287 | 604 | 0 |
| SCEGKGVYVYDLPSKFNKDLLVECNDILPGNLGQGWFKTHKYSLEPILHSRFLKHPCRVYNETQAKLFYVPYYGGFDVLRWHYRNVSDDVKDQLGIEVLK WLESKESWKINSGKDHVFVLGKITWDFRRDKVPWGSRFLELQEMQNPTKLLIERQPWQVNDIAVPHPTYFHPQTDEDITSWQIKIMSKPRRSLVSFAGGA RHSNPNSIRSTLFDQCISLSSDDQCRFLNCTNGSCKNPKNVIDLFKDSEFCLQPPGESVTRRSVFNSLISGCIPVIFNPYTAYYQYAWHLPEDHRRYSVY ISEEDVKEKRVNVVEILK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 657 Download |
| MVASISKRKS RSSTKTEDSR IFFCNNLCST FFRSILWLTL LTILFFFIIY LWLSFTTLIS 60 NNVLHICVFS RKLNDPYCLT AGSKPRFQIP RNLKSKSVVH SKDEEIVPGK NETFSGAILG 120 DTNSQDENFS DDDKDGEMGS RKYFTLAGKT AGDMISDGEE YDVVEQERRL KNLDTVLDQE 180 HNAKNLDSFL GDKGGEMGSK KDDTFAGVIA RNRVPHDRTK IFQILDQEPK PKNKVDLISL 240 IDLKAEVEYN RYIKPKSEGQ GHALRAVIKY LYLQRSWLSL GNNKPRSCEG KGVYVYDLPS 300 KFNKDLLVEC NDILPGNLGQ GWFKTHKYSL EPILHSRFLK HPCRVYNETQ AKLFYVPYYG 360 GFDVLRWHYR NVSDDVKDQL GIEVLKWLES KESWKINSGK DHVFVLGKIT WDFRRDKVPW 420 GSRFLELQEM QNPTKLLIER QPWQVNDIAV PHPTYFHPQT DEDITSWQIK IMSKPRRSLV 480 SFAGGARHSN PNSIRSTLFD QCISLSSDDQ CRFLNCTNGS CKNPKNVIDL FKDSEFCLQP 540 PGESVTRRSV FNSLISGCIP VIFNPYTAYY QYAWHLPEDH RRYSVYISEE DVKEKRVNVV 600 EILKAKTLKE KDDMRSYIVH QLLPGLVYGD SNAKFEKFRD AFDITFDSLL EKINKS* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-70 | 287 | 605 | 334 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176534.2 | 0 | 1 | 656 | 24 | 663 | catalytic [Arabidopsis thaliana] |
| RefSeq | NP_198941.1 | 0.00000000000001 | 5 | 128 | 2 | 104 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_198941.1 | 0 | 194 | 656 | 79 | 559 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002299537.1 | 0.0000006 | 1 | 118 | 1 | 107 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002299537.1 | 0 | 263 | 655 | 164 | 571 | predicted protein [Populus trichocarpa] |
