| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_003271m |
| Family | GT47 |
| Protein Properties | Length: 653 Molecular Weight: 74782.3 Isoelectric Point: 9.6757 |
| Chromosome | Chromosome/Scaffold: 00847 Start: 653881 End: 657174 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 321 | 603 | 0 |
| RMLRIYIYKEGEKPIFHQSKMRGIYASEGWFIKLLEGNKKFIVRDPRKAHLFFLPFSSQMLRTTLFEQNFWSQKDLEEYLKNYVDLVARKYSFWNRTGGA DHFLVGCHDWASRITRQYMKNCIRVLCNANVAKGFKIGKDTTLPVTYVRSAENPLKDLGGTPPSERHILAFFAGGMHGYLRPILLQYWQNKESDMKIFGP MRRDIEGKNAYREYMKSSKYCISARGYEVHTPRIIEAIFYECVPVIISDNYVPPFFEVLNWEAFSVFVQEKDIPKLRNILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 653 Download |
| MGITAQFRKL CLVEIRKLLM VTCVAIIIAA LFQCFALPYG KRWSLLTADE GSIVVLISND 60 TFSNNLRLRP INVSSIMVND TFYPSDLDGE VGDENDTKGT STHNLSTDKS ERGELTFKMD 120 AMLGKSLIMG YEARTGDSSI QATSLENGHG KVKHAEKVDD KEAAVGLTYG GVQIQAGIVP 180 VVLPGISAKN GEKMDTESST WNAFLPANLI SMDNVTGIAE VGPQTLVSVT SDKNSKRDRI 240 STLKRWETQP TSISQMNSQL LQNIVSSHYA RRQLYSVRDR ELLSAKLKIQ NAPFVRSPPG 300 LYASAFRNFS IFKRSYELME RMLRIYIYKE GEKPIFHQSK MRGIYASEGW FIKLLEGNKK 360 FIVRDPRKAH LFFLPFSSQM LRTTLFEQNF WSQKDLEEYL KNYVDLVARK YSFWNRTGGA 420 DHFLVGCHDW ASRITRQYMK NCIRVLCNAN VAKGFKIGKD TTLPVTYVRS AENPLKDLGG 480 TPPSERHILA FFAGGMHGYL RPILLQYWQN KESDMKIFGP MRRDIEGKNA YREYMKSSKY 540 CISARGYEVH TPRIIEAIFY ECVPVIISDN YVPPFFEVLN WEAFSVFVQE KDIPKLRNIL 600 LSIPEERYLA MQLRVKMIQQ HFLWHKNPVK YDLFHMILHS VWYNRIFQMS SK* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-62 | 323 | 603 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 1 | 648 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 1 | 649 | 1 | 710 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI28021.1 | 0 | 1 | 652 | 1 | 665 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002280595.1 | 0 | 3 | 652 | 1 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514249.1 | 0 | 319 | 652 | 1 | 334 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
