| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_006323m |
| Family | GT47 |
| Protein Properties | Length: 492 Molecular Weight: 56500.6 Isoelectric Point: 7.9939 |
| Chromosome | Chromosome/Scaffold: 06859 Start: 20397 End: 24071 |
| Description | exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 112 | 415 | 0 |
| EPLKVFMYDLPAEFHFELLDWTPQGDSVWPDVKTKIPSYPGGLNLQHSIEYWLTLDILASEIPGIPRAGSAVRVRNSSEADVIFVPFFSSLSYNRYSKVN PHQKKSKNKLLQEKLVKFVTSQREWKRSGGRDHIILAHHPNSMLDARMKLWPAMFILADFGRYPPNVANVDKDVIAPYKHVVRSYVDDLSTFDSRPILLY FQELFYLLKDEKDVHFQFGSIQKDGVTKASKGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPYEDVLDYSQFCIFVRTSDAVKEKFLINL IRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 492 Download |
| MAEKHVSSHG FVSRKYLLCL FSFILALFIL SWFFVLRSTH RPNFTDHSLL TNPLHSVIDD 60 GSSLSWTQKI DEPQLENRGE VSGGGAEGEE SPKEKVAGED VKCNTHNENN KEPLKVFMYD 120 LPAEFHFELL DWTPQGDSVW PDVKTKIPSY PGGLNLQHSI EYWLTLDILA SEIPGIPRAG 180 SAVRVRNSSE ADVIFVPFFS SLSYNRYSKV NPHQKKSKNK LLQEKLVKFV TSQREWKRSG 240 GRDHIILAHH PNSMLDARMK LWPAMFILAD FGRYPPNVAN VDKDVIAPYK HVVRSYVDDL 300 STFDSRPILL YFQELFYLLK DEKDVHFQFG SIQKDGVTKA SKGMHSSKFC LNIAGDTPSS 360 NRLFDAIASH CVPVIISDDI ELPYEDVLDY SQFCIFVRTS DAVKEKFLIN LIRGIGKDEW 420 TQMWQKLKEV EHFFEFQYPS KEGDAVQMIW QAVARKVPSM RMKIHKSKRY SQSLMVNNRE 480 LKKIPTPNNF W* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-51 | 111 | 415 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33321.1 | 0 | 1 | 491 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | XP_002268382.1 | 0 | 1 | 491 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002319201.1 | 0 | 1 | 471 | 3 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325457.1 | 0 | 81 | 491 | 40 | 463 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 1 | 488 | 1 | 497 | catalytic, putative [Ricinus communis] |
