| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_022793m |
| Family | GT47 |
| Protein Properties | Length: 387 Molecular Weight: 43938.6 Isoelectric Point: 9.5242 |
| Chromosome | Chromosome/Scaffold: 04142 Start: 227795 End: 229556 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 61 | 373 | 0 |
| NKVKIFMYDLPKKFTTGIIEQHALARGSKDASQAKYPGHQHMGEWHLFSDLNRPERDRIGSPLIKVDDPDEADLFYVPVFSSLSLIVNPIRPAGAEPVSV PQYSDEDMQEQLVKWLEKQVYWRRNRGRDHVIIAGDPNALYRVLDKVKSAILLLSDFGRVRPDQGSLVKDVIIPYAHRINTYNGDIGVKDRKTLLFFMGN RYRKDGGKIRDLLFQMLENEEDVIIKHGTQSRESRRAASRGMHTSKFCLNPAGDTPSACRLFDAIVSLCVPVIVSDGIELPFEYNIDYTKIAIFVGTTAS LKPGYLVKMLRKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 387 Download |
| MARKSSLLKQ TIVLSAFSIL AIYALLNTFF NPTIFPSSLF AEHHSRDNFG FPGEVAKSDV 60 NKVKIFMYDL PKKFTTGIIE QHALARGSKD ASQAKYPGHQ HMGEWHLFSD LNRPERDRIG 120 SPLIKVDDPD EADLFYVPVF SSLSLIVNPI RPAGAEPVSV PQYSDEDMQE QLVKWLEKQV 180 YWRRNRGRDH VIIAGDPNAL YRVLDKVKSA ILLLSDFGRV RPDQGSLVKD VIIPYAHRIN 240 TYNGDIGVKD RKTLLFFMGN RYRKDGGKIR DLLFQMLENE EDVIIKHGTQ SRESRRAASR 300 GMHTSKFCLN PAGDTPSACR LFDAIVSLCV PVIVSDGIEL PFEYNIDYTK IAIFVGTTAS 360 LKPGYLVKML RKITTKRILE YQKELKE 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-74 | 61 | 373 | 324 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 62 | 386 | 59 | 384 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 62 | 386 | 59 | 384 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002318294.1 | 0 | 67 | 387 | 1 | 320 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322391.1 | 0 | 1 | 387 | 1 | 395 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 387 | 1 | 390 | catalytic, putative [Ricinus communis] |
