| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_026933m |
| Family | GT47 |
| Protein Properties | Length: 393 Molecular Weight: 45210 Isoelectric Point: 9.046 |
| Chromosome | Chromosome/Scaffold: 05005 Start: 291885 End: 293396 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 58 | 343 | 0 |
| EKRFKVWVYKEGEPPLVHGGPVNDIYGIEGQFIDEVESGKSHFLARNPNEAHVFFLPISVASIINFLYKPLITYSRDQLQRLVTDYINIVADKHPYWNRS NGGDHFLISCHDWAPDISLANPELYKNLIRVLCNANTSEGFQPHRDVSLPEIIIPKAKLGPPHGQDVAPTNRTILAFFAGGCHGYIRELLLDHWKHKDNE IQVHESLHKKMKNYFELMGRSKFCPCPSGYEVASPRVVTAIQLGCVPVIISDNYTLPFSDVLDWSKFSVHIPSEKIPEIKKILEGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 393 Download |
| RNNGGFERIE DGLVRARAAI REAVRLQNFS SCKEESYVPG GAIYRNSYAF HQSYIEMEKR 60 FKVWVYKEGE PPLVHGGPVN DIYGIEGQFI DEVESGKSHF LARNPNEAHV FFLPISVASI 120 INFLYKPLIT YSRDQLQRLV TDYINIVADK HPYWNRSNGG DHFLISCHDW APDISLANPE 180 LYKNLIRVLC NANTSEGFQP HRDVSLPEII IPKAKLGPPH GQDVAPTNRT ILAFFAGGCH 240 GYIRELLLDH WKHKDNEIQV HESLHKKMKN YFELMGRSKF CPCPSGYEVA SPRVVTAIQL 300 GCVPVIISDN YTLPFSDVLD WSKFSVHIPS EKIPEIKKIL EGISHRRYLQ LQRRVMKVKK 360 HFVLNRPAQP YDMIHMILHS VWLRRLNLRL PY* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-66 | 57 | 327 | 289 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25529.1 | 0 | 6 | 390 | 4 | 386 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197526.4 | 0 | 3 | 391 | 19 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 3 | 391 | 77 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002324625.1 | 0 | 57 | 392 | 1 | 335 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531945.1 | 0 | 1 | 392 | 71 | 452 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EC939466 | 290 | 8 | 291 | 0 |
| FD507587 | 228 | 100 | 327 | 0 |
| FE523338 | 286 | 35 | 319 | 0 |
| JK524792 | 255 | 40 | 291 | 0 |
| CV281186 | 222 | 174 | 391 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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