| Basic Information | |
|---|---|
| Species | Manihot esculenta |
| Cazyme ID | cassava4.1_028082m |
| Family | GT47 |
| Protein Properties | Length: 385 Molecular Weight: 44677.8 Isoelectric Point: 9.5504 |
| Chromosome | Chromosome/Scaffold: 12793 Start: 139952 End: 142271 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 50 | 335 | 0 |
| EKRFRVWVYKEGEPPLVHIGPVIDIYGIEGQFIDEMESGKSHFLARNPDEANVFFIPISITNIISYVYNPLVTFSRAQLQNIVTDYIGVISDKYPFWNRS NGADHFLISCHDWAPDVSKANPELYKNFIHVLCNANYSEMYQPQRDISMPEIKIPPGKLLGTSPRDGQPPSKRTILAFFAGGSHGYIRKVLLNHWKDKDD EIQVHEYLDKKKNYFKLMGRSKFCLCPSGYEVASPRVVTAIQLGCVPVIMSENYTLPFSDVLDWSKFTVRIPLEKIAEIKTILKRI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 385 Download |
| MEDCLARSRA AIREAVRTQK CSSCKEKTFV PRGAIYRNSY AFHQSYIEME KRFRVWVYKE 60 GEPPLVHIGP VIDIYGIEGQ FIDEMESGKS HFLARNPDEA NVFFIPISIT NIISYVYNPL 120 VTFSRAQLQN IVTDYIGVIS DKYPFWNRSN GADHFLISCH DWAPDVSKAN PELYKNFIHV 180 LCNANYSEMY QPQRDISMPE IKIPPGKLLG TSPRDGQPPS KRTILAFFAG GSHGYIRKVL 240 LNHWKDKDDE IQVHEYLDKK KNYFKLMGRS KFCLCPSGYE VASPRVVTAI QLGCVPVIMS 300 ENYTLPFSDV LDWSKFTVRI PLEKIAEIKT ILKRISQRRY LQLQRRVMLV RKHFVVNRPA 360 QPYDMIDMVL HSLWLRRLNL RLPY* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-69 | 49 | 335 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_197526.4 | 0 | 1 | 383 | 27 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 1 | 383 | 85 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002324625.1 | 0 | 49 | 384 | 1 | 335 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002331029.1 | 0 | 49 | 384 | 1 | 336 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531945.1 | 0 | 1 | 384 | 79 | 452 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EC939466 | 288 | 1 | 283 | 0 |
| FD507587 | 230 | 92 | 321 | 0 |
| FE523338 | 310 | 17 | 324 | 0 |
| CV281186 | 223 | 166 | 383 | 0 |
| CO983212 | 232 | 151 | 382 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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