y
Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a010020m |
Family | GT47 |
Protein Properties | Length: 325 Molecular Weight: 37327 Isoelectric Point: 8.2631 |
Chromosome | Chromosome/Scaffold: 13 Start: 252602 End: 254348 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 2 | 248 | 0 |
DPEEADLFYVPFFSSLSLVANPIRSATVNVSPNRTVYNDEQTQEALMEWLEEQVYWKRNNGWDHVFICQDPNALYKIIDRVKNGVLLVSDFGRLGANQAS LVKDVILPYSHRINSYKGEIGLENRKSLLFFMGNRYRKEGGKIRDMLFQVLENEQEVIIKHGAQSRESRRMASQGMHTSKFCLHPAGDTPSACRLFDAIV SLCVPVIVSDYIELPFEDVIDYRKIAIFLDTYTAVKPGSLVKLLRKV |
Full Sequence |
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Protein Sequence Length: 325 Download |
MDPEEADLFY VPFFSSLSLV ANPIRSATVN VSPNRTVYND EQTQEALMEW LEEQVYWKRN 60 NGWDHVFICQ DPNALYKIID RVKNGVLLVS DFGRLGANQA SLVKDVILPY SHRINSYKGE 120 IGLENRKSLL FFMGNRYRKE GGKIRDMLFQ VLENEQEVII KHGAQSRESR RMASQGMHTS 180 KFCLHPAGDT PSACRLFDAI VSLCVPVIVS DYIELPFEDV IDYRKIAIFL DTYTAVKPGS 240 LVKLLRKVTP ERILEFQKEL KKVKRYFEYE EANGTVKEIW RQVSLKLPLI KLMSNRDKRI 300 VLRDLTQPDC SCLCSNHSGV HTTL* 360 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-65 | 2 | 248 | 258 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 2 | 324 | 141 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002276440.1 | 0 | 2 | 324 | 174 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318294.1 | 0 | 2 | 324 | 62 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 2 | 324 | 137 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 2 | 324 | 131 | 452 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EH727363 | 270 | 56 | 325 | 0 |
EX674423 | 299 | 16 | 314 | 0 |
GR006880 | 212 | 114 | 325 | 0 |
DY359337 | 262 | 54 | 315 | 0 |
GR006880 | 16 | 98 | 113 | 7.2 |
Sequence Alignments (This image is cropped. Click for full image.) |
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