LOCUS       NZ_DS264579            16893 bp    DNA     linear   CON 25-NOV-2019
DEFINITION  Bacteroides ovatus ATCC 8483 Scfld0226, whole genome shotgun
            sequence.
ACCESSION   NZ_DS264579
VERSION     NZ_DS264579.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN00627058
            Assembly: GCF_000154125.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacteroides ovatus ATCC 8483
  ORGANISM  Bacteroides ovatus ATCC 8483
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 16893)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides ovatus (ATCC 8483)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16893)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides ovatus (ATCC 8483)
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 16893)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   4  (bases 1 to 16893)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   5  (bases 1 to 16893)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/25/2019 16:35:53
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.10
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 4,931
            CDSs (total)                      :: 4,837
            Genes (coding)                    :: 4,690
            CDSs (with protein)               :: 4,690
            Genes (RNA)                       :: 94
            rRNAs                             :: 4, 4, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 149
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 1 of 149
            Pseudo Genes (frameshifted)       :: 75 of 149
            Pseudo Genes (incomplete)         :: 69 of 149
            Pseudo Genes (internal stop)      :: 17 of 149
            Pseudo Genes (multiple problems)  :: 14 of 149
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            DS264579.
            Bacteroides ovatus (GenBank Accession Number for 16S rDNA gene:
            X83952) is a member of the division Bacteroidetes. In one
            comprehensive 16S rDNA sequence-based enumeration of the colonic
            microbiota of three healthy adult humans, it represents, on
            average, 0.034% of all 16S rDNA sequences and 0.071% of the
            sequences in its division (Eckburg et. al. (2005)). The sequenced
            strain was obtained from ATCC (ATCC 8483T).
            We have collected 6.9X coverage in plasmid end reads and 454 reads.
            We will be performing one round of automated sequence improvement
            (pre-finishing).
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences.  454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Bacteroides ovatus (GenBank Accession Number for 16S rDNA gene:
            X83952) is a member of the division Bacteroidetes. In one
            comprehensive 16S rDNA sequence-based enumeration of the colonic
            microbiota of three healthy adult humans, it represents, on
            average, 0.034% of all 16S rDNA sequences and 0.071% of the
            sequences in its division (Eckburg et. al. (2005)). The sequenced
            strain was obtained from ATCC (ATCC 8483T).
            We have collected 6.9X coverage in plasmid end reads and 454 reads.
            We will be performing one round of automated sequence improvement
            (pre-finishing).
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences.  454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions notspanned by GeneMark and Glimmer2 were
            blasted against NCBI'snon-redundant (NR) database and predictions
            generated based on proteinalignments. RNA genes were determined
            using tRNAscan-SE 1.23 or Rfamv8.0. Gene names are generated at the
            contig level and may notnecessarily reflect any known order or
            orientation betweencontigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in August 2007, and the CDS
            comments were updated in January 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
FEATURES             Location/Qualifiers
     source          1..16893
                     /organism="Bacteroides ovatus ATCC 8483"
                     /mol_type="genomic DNA"
                     /strain="ATCC 8483"
                     /isolation_source="biological product [ENVO:02000043]"
                     /host="Homo sapiens"
                     /type_material="type strain of Bacteroides ovatus"
                     /db_xref="ATCC:8483"
                     /db_xref="taxon:411476"
                     /note="type strain of Bacteroides ovatus ATCC 8483"
     gene            1..2403
                     /locus_tag="BACOVA_RS11920"
                     /old_locus_tag="BACOVA_02738"
     CDS             1..2403
                     /locus_tag="BACOVA_RS11920"
                     /old_locus_tag="BACOVA_02738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008646742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="WP_004298554.1"
                     /translation="MKKLLCLALLVSAGSIYSGSISANNKPTDNKSGNNSKDIYKKTWI
                     DFNKNGIKDVYEDPSAPIEARIADLLSQMTLEEKTCQMATLYGSGRVLKDAWPTTGWST
                     EIWKDGIGNIDEQANGLGKFGSEISYPYANSVKNRHTIQRWFVEQTRLGIPVDFTNEGI
                     RGLCHDRATMFPAQCGQGATWNKKLIGEIAKVTADEAKALGYTNIYSPILDIAQDPRWG
                     RVVESYGEDPYLVGELGKQMILGLQNEGIVATPKHFAVYSIPVGGRDGGTRTDPHVAPR
                     EMKTLYLEPFRKGIQEAGALGVMSSYNDYDGEPVSGSYHFLTEILRQQWGFKGYIVSDS
                     EAVEFLHTKHRITPTEEEMAAQVVNAGLNIRTNFTPPQDFILPLRRAINEGKVSLHTLD
                     QRVGEILRVKFMMGLFDNPYPGDDRRPETVVHNDAHKAVSMKAALESIVLLKNENQMLP
                     LSKNFSKIAVIGPNGEEVKELTCRYGPANASIKTVYQGIKEYLPNSEVRYAKGCDIIDK
                     YFPESELYNVPLDTQEQAMIQEAVELAKASDIAILVLGGNEKTVREEFSRTNLDLCGRQ
                     QQLLEAVYATGKPVILVMVDGRAATINWANKYIPAIIHAWFPGEFMGDAIAKVLFGDYN
                     PGGRLAVTFPKSVGQIPFAFPFKPGSDSKGKVRVDGVLYPFGYGLSYTTFGYSDLKISK
                     PVIGPQENITLSCTVKNTGKKAGDEVVQLYIRDDFSSVTTYDKVLRGFERIHLQPGEEQ
                     TVNFTLTPQDLGLWDKNNQFTVEPGSFSVMVGASSQDIRLKGSFEVQ"
     gene            2901..6872
                     /locus_tag="BACOVA_RS11925"
                     /old_locus_tag="BACOVA_02740"
     CDS             2901..6872
                     /locus_tag="BACOVA_RS11925"
                     /old_locus_tag="BACOVA_02740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008023456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-SUPERFAMILY|0035607"
                     /protein_id="WP_004298556.1"
                     /translation="MVRFNLVITLLLMISIAVKAELTNRMFDVRHVGYAEGLSSQRVFS
                     IVEDGDGAMWIATKTGIDRYNGHTVKNYDLPGSFYYGDLAGRRLYLLYDAQQGLFAYDH
                     TGRIYRYSTILDHFEQVLHLGQLIQEEVILNKLCLDSDGTWWMGADKGLYKQEADHRIV
                     AVLKGQYVNDIAFAGESLFVGTSNGVWQLSHALPDKKRQLLEGWNVQTLFCDKPKKELW
                     IGTFGSGLSVMNLDTSKVLALEGQGSTFLHPIRAITDYDVHTILIGVDGGGVYAIDKDT
                     KKARLLMNTKDDTDTYLRGNGVYAVTRDDQGNIWIGSYTGGVSVAILLKHPISILAHEK
                     GNTHSLISNNVNDIEENPDGNQWFATDDGISIRNTLSGTWKHVLKEIVTISLCTSGNGN
                     VWVGTYGDGVYLLDNNGRVLRHLTKQQGQLTTNYIFSVRQDMEGDLWIGGLDGCLIMFE
                     KEKGSRQSFDVNWVQSIEPIDRNRVAVATVNGFFLVDKHTGNIQHYANSQEFHNQNVSA
                     YIISMLFNDDGTVWLGTEGGGLNLYDMKNRTVKTFTVQEGLPSNDIYSLQRDDKKRLWV
                     STGKGIALIDSLRVSNLNYAGNIDKEYNKSSFARLMNGEFVYGSTDGAVFIMPLDISTV
                     DYWTLLRFTGLTVDYQNVQEEESLRPAIHDMLADRAVRLGYKYNSFTVSFESINYRFQR
                     DIVYQHILEGYDNDWSKPSAEGKASYTKVSPGTYLFKVRSLRRSDGKTISESTLEVKVS
                     QPWWNSWWAWTIYLFIIGFVFYFILRYKSNQLQKKYDEDKIRFFIDTAHDIRTPVTLIM
                     APLEDLNREQDLSDKARYYLNLAHESTQKLHSLITQLLEFEKVDAHKPSSSSVPLCLNE
                     VLLKEVSVFRSFCEKKQLTLNLTQPDESVFVSADKHLIEMLLDNLLSNACKYTMPQGEI
                     SLDLKATKRKAILSLKDNGIGIPKKAKKHIFSDIYRAENARQSQEEGTGFGLLQVQRIV
                     KMLHGKITFCSEEGKGTTFIVTLPRTTTVAEPVSHESSLEHLAGTSDNNSPETDKMKDP
                     DDRNTLLIVEDHETLRHYLRQTFEHLYRVIDVADGHEAIACLANEYPDIILSDVMMPGI
                     RGDELCRMVKENPDTSGIPVVLLTAKANHEAIVEGLKKGADDYIPKPFSTEILKLKVQG
                     LIDNRNRQRQFFMRQAIAQVEAGGKRDDNESNENNESIDNKNVTTASETMAEGDRRFIM
                     QATRFVLEHLDEPDFNINLLCHEMAMSRTLFYSRLKSLTGKGPQEFIRIIRLQKAAELL
                     KEGKSVTDVATETGFVNTKYFSSLFKKQFGMQPSKYSGK"
     gene            7491..8306
                     /locus_tag="BACOVA_RS11930"
                     /old_locus_tag="BACOVA_02741"
     CDS             7491..8306
                     /locus_tag="BACOVA_RS11930"
                     /old_locus_tag="BACOVA_02741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH16"
                     /protein_id="WP_004298557.1"
                     /translation="MKKVALFLFLSVCFAQQSCSSDSVGTEPEENPQDILFKDDFNFFD
                     EKVWTKETHEPGWTNQELQAYDAAHVSVGKDGDKSVLILTAERKGNKIYSGRINSKGKK
                     SFKYRKIEASIKLPKTNGGLWPAFWMMGDNDKQWPACGEIDIMEMGEQSGMAAGDSEKQ
                     VNTAIHYGPSAAAHEQQYYKANVANSLQDGNYHTYSLDWDENNLTISIDNVKFHTFDIS
                     SNTYFHDNFYILFNLAVGGAFTGITDINKLTGLKDGQKVNMYIDWVKIL"
     gene            8327..11515
                     /locus_tag="BACOVA_RS11935"
                     /old_locus_tag="BACOVA_02742"
     CDS             8327..11515
                     /locus_tag="BACOVA_RS11935"
                     /old_locus_tag="BACOVA_02742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q93TH9|1.B.14.6.2"
                     /protein_id="WP_004298558.1"
                     /translation="MNMEKCKYLLFCGTLALWMAGSFQQVYAATEPSSQAIQQQSNKVT
                     GKVSDATGPIIGASVVEKGTANGTITDLDGNFSLNVKAGATLVVSYVGYKSEEVKAGRG
                     PLNITLKEDAKALDEVVVTALGIKRERKALGYGIDEVKGEALTKAKETNLINSMAGRVP
                     GLVVSQTAGGPSGSTRVILRGSTEMTGNNQPLYVVDGVPLDNTNFGSAGTNGGFDLGDG
                     ISSINADDVENMSVLKGPAASALYGSRASHGVILITTKRANKDKISVEYNGTLTFDTQL
                     AKWDEVQQIYGMGSNGTYSYDAISNTNKSWGPKADGSNMLKYFDGVERPFLIVPDNTSN
                     FFRTGITATNSAIIGVNSGKTGIRFTYTDMRNKDIVPQTHMSRDIFNLRANTSAGKVDL
                     DFSVNYTREDVKNRPALGDSKSNIGKNLMTLATTYDQEWLQTYQTADGEYSNWNGMDPY
                     NVNPYWDIYKNFNKSKKDLFRMNGKAVWNIDPHLKLQATLGAELNWFTFDDYKAPTTPG
                     FEAGRLQNSAFRNRMYNFEALALYNNHWGDFDFNATLGGNVYKVNNQTTVTTAQDMKIR
                     DVPSLTSFNEISVVPGSYRKQINSVYGAVNVGWKHMLYLDATLRGDQSSTLPTGNNMYV
                     YPSFSGSFVFSELTKLGDLLPYGKVRMSWAQVGSDTDPYQLGLVYTKSKYAYPGYTIGY
                     IDNGTIPNKDLKPTKTNSVEMGLELKFLKNRIGLDFTYYSQISKNQIMGMASSWTTGYN
                     YRLINAGKIENKGIEIALSTRPIQTRDFSWDINLNFSKNSNKVKELDGESDMFELEKAS
                     WLDVQVAAKVGENFGSIVGPDFQRNEKGDILIDPQTGLPQYDKSNHVLGNASWDWTGGL
                     LTNFTYKNLSLVAVFDVKVGADLYSMSARAAYESGKSPETLAGRDAWYRSEEERLAAGI
                     AKGADNWKPTGGFVAPGVIDNGDGTYRPNDIYINPEDYWMSVCRNAPSMFIYDNSYVKC
                     RELTLSYNVPKSWLKNVVSGLTVSFVARNPFIVWKNIPNIDPDSNYNNTTGMGLEYGSL
                     PSRRSYGFNVNVKF"
     gene            11527..13203
                     /locus_tag="BACOVA_RS11940"
                     /old_locus_tag="BACOVA_02743"
     CDS             11527..13203
                     /locus_tag="BACOVA_RS11940"
                     /old_locus_tag="BACOVA_02743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004302737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8A8X0|8.A.46.2.1"
                     /protein_id="WP_004298559.1"
                     /translation="MRQSKYITIITMACALFFASCSDEYMENMNTDPSKAATIDPNAQL
                     TTAQLQTYGDLSMMEIYRNYHYAFTQQLMGCWNTTNYGGRHTLDNNEMSRIWTSFYTQS
                     LKNIIDAQYRTAEDAEKVNINSVLRIYRVYLMSIITDTYGDAPFSEAGLGFLEGKFNPK
                     YDKQEDIYNAFFLELEDAVNKIDPTKDKVTGDLIYAGDVTKWQQLANSLRLRFAMRISS
                     VNPTKAQTEFENALAANGGVITDASSDALIKYMTIAFSFGQEAYSDYRGNSLSQLLFGN
                     DPANNPSYLCSTFFNQLYNSGDPRTFKISRCYYDGLMSATSPDNRVDITQEMIEKGIAF
                     SPRDPGAYSWEPWPTGYDSDICAELAVNNPSVTATMAREVEPKLANNFLKSDNPGVVMT
                     SAEVKFLMAEATVKKWNVGSVSAEDLYKQGVRAAIDFLTDNYGCTATTDAEFDAFIQDK
                     GAFGHTDNQKLEAINTQAWILHFTNPAECWANVRRSGYPKLKSPAEYGFGQYLTGGTEI
                     PVRLCYPVLESSYNKKSYNEAIERMGGTDNWHSLLWWDTEN"
     gene            13224..14486
                     /locus_tag="BACOVA_RS11945"
                     /old_locus_tag="BACOVA_02744"
     CDS             13224..14486
                     /locus_tag="BACOVA_RS11945"
                     /old_locus_tag="BACOVA_02744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_004298560.1"
                     /translation="MKKIYIALFALLAVGSTFTACTEEEPFATVTENDDPHILAPVFPD
                     RTNGQLATFANISRDANLSIALTVTPKDYTTVTWFIDGQEVESGTDSDKEINRSLKAGT
                     YNLKIEVETVKGKKTSREGLVVVNPLADDPQSKEVAFERIVSPGKTARLYGSNLQNVTA
                     ILLGGNTITDPTYVESADENYLEYTIPTGVSEGDYRIVLQDADGNQYGADMVKVTNASL
                     VISGANRATANVDWTISGINLENIASLTIGGQTVSQFSNQSSTEITLTCPDLSDGSYTM
                     TGKTRSGEAVQFLNDNITTTEQTVTVSTEITLWSGHHYVSWDKPDGDPNKTFGLIPMDV
                     FAGITAGSTLKVVYSIEPTAEYHKMQLATGYWTGLASEMEFTENGEYTLILTQDMLNKI
                     QAEAGFLCVGHGYYVDLVTVK"
     gene            14599..16893
                     /locus_tag="BACOVA_RS11950"
                     /old_locus_tag="BACOVA_02745"
     CDS             14599..16893
                     /locus_tag="BACOVA_RS11950"
                     /old_locus_tag="BACOVA_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="WP_004298561.1"
                     /translation="MKLRNIILMTASIAMTACSKQAVPTAIPEDAKIEQQVEELLSKMD
                     LDAKIGQMTELAIDVLGETINGEFQLDEAKLHKAIAEYKVGSFLNAPGPVAQSPEKWNE
                     IIGRIQELSMAEIGIPCIYGLDQNHGTTYTLGGTLFPQNINMGAAFNPDLTYEAARVTA
                     YETRASNCPWTYSPTVDMARDPRWPRVWENYGEDCLVNAIMGSTAVRGFQGDDPNHIPA
                     DRIATSVKHYMGYSMPRTGKDRTPAYISVSELREKCFAPFRACVEAGALTIMVNSGSIN
                     GKPVHADRELLTQWLKEDLGWDGMLITDWADINNLYTREHVAANKKEAIEMAINAGIDM
                     AMEPYDLNYCTLLKELVQEKKIPMSRIDDAVRRVLRLKFRLGLFDHPNTLLKDYPLFGS
                     KEHALIALHAAEESEVLLKNKDNILPLPQGKKLLVTGPNANSMRCLNGGWSYSWQGHLT
                     DRFADKYNTIYEAICNKFGADHVRLEQGVTYKPEGAYMEENEPEIEKAVAAARNVDIII
                     ACIGENSYCETPGNLSELAISASQSKLVKALAATGKPIILILNEGRPRIINELEPLADA
                     VIDILLPGNYGGDALANILAGDVNPSAKMPYTYPRHEAALTTYDYRVSEEMDKMEGAYD
                     YNAVVSVQWPFGYGLSYTTFEYSNFQTDKSSFTAGDDLHFSIDVTNTGKYAGKEVVMLF
                     SSDLVASLTPENRRLRAFKKVELQPGETQTITLSIKGSDLAFVNSDGQWVLEQGDFRMQ
                     CGNQTLNIICK"
ORIGIN
        1 atgaagaaac tgctatgtct cgccctgtta gtatctgccg gaagtatcta ctccggaagt
       61 atctcggcaa acaacaaacc tactgataac aaatccggca acaactcaaa ggacatatac
      121 aaaaagacct ggatcgactt caataaaaac ggtataaagg atgtatacga agatccctcc
      181 gctcctatcg aagcccgcat cgccgacctg ctctcgcaaa tgacgctgga agagaaaacc
      241 tgtcagatgg ccactctcta cggttcggga cgggtattga aagatgcatg gcctaccacc
      301 ggatggtcaa cggaaatctg gaaggacggt atcggtaata ttgatgagca ggcgaacgga
      361 ctgggtaaat tcggttctga aatctcctat ccgtatgcca acagcgtaaa gaaccgacac
      421 accattcaac gctggtttgt ggaacagaca cgactgggta ttccggtgga ctttaccaat
      481 gaaggaatac gcggattatg tcacgaccgg gctaccatgt ttcccgctca atgcgggcaa
      541 ggtgccacgt ggaacaaaaa actgatcggg gaaattgcga aagtcactgc agatgaggca
      601 aaagcattgg gatataccaa tatttattct cctattctgg atatagcaca agatcctcgc
      661 tggggacgtg tggtggaaag ttatggggaa gatccttatc tggtgggcga attgggaaaa
      721 cagatgattc tcggtctgca aaatgaaggt atcgttgcta ctccgaaaca ttttgccgtt
      781 tacagtattc cggttggtgg acgtgacgga ggtacgcgta cggatccgca cgtggctccg
      841 cgtgagatga agactcttta tctggaacct ttccgcaaag gtattcagga agcgggtgct
      901 ctaggagtga tgagttcgta taatgattat gatggggagc ctgtttccgg aagttatcat
      961 ttcctcacgg aaattctgcg tcagcaatgg ggattcaaag gatatatagt atcggatagt
     1021 gaggcggtag agtttctgca caccaaacat cgtatcaccc cgactgaaga agagatggca
     1081 gcacaagtgg tcaatgcagg attgaatatc cgtaccaact ttactccgcc acaagatttc
     1141 attctcccgt tgcgccgtgc tatcaacgaa ggcaaagttt ctttgcacac gctcgatcaa
     1201 cgtgtcggtg agattctccg tgtcaagttt atgatgggac tttttgataa tccgtatccc
     1261 ggtgatgacc gtcgtccgga gacagtggta cacaacgacg ctcataaagc agtatctatg
     1321 aaagccgctt tagagtccat cgttcttttg aagaatgaga atcagatgct tccgttatcc
     1381 aagaacttca gcaaaatagc tgtgattggt ccgaatgggg aagaagtgaa ggaactgact
     1441 tgcagatatg gtcccgccaa tgcgtctatt aagactgtat atcagggaat caaagaatat
     1501 ctgcctaact cggaagttcg ctatgctaaa ggctgtgata ttattgataa gtatttcccg
     1561 gagagcgaac tgtacaatgt tccattagat acacaagagc aggcgatgat tcaggaagcg
     1621 gtagaattag caaaagcttc ggatatcgct attcttgtac tgggtggaaa tgagaaaacg
     1681 gttcgggaag agttttcacg taccaatctt gacctctgcg gacggcagca acaattattg
     1741 gaagcggttt atgcaacagg taaacctgtc attctagtga tggtggacgg aagggcagca
     1801 accatcaact gggcaaacaa atacattcct gccatcattc atgcctggtt ccccggagaa
     1861 tttatggggg atgccatcgc taaagttctt ttcggagact ataatccggg aggacgtctg
     1921 gctgtcactt tcccgaaatc tgtgggacag attccttttg ctttcccatt caagccgggt
     1981 tctgactcca aagggaaagt ccgtgtagac ggtgtacttt atcctttcgg atatggttta
     2041 agctatacaa ccttcggata ttcagacttg aaaatatcta aaccggtgat cggtccgcag
     2101 gaaaatatca ctctttcatg tactgtaaag aatacaggaa agaaagcagg ggacgaagta
     2161 gtccagcttt atatccggga tgatttcagc agcgtaacca cctacgataa agtattgcgt
     2221 ggctttgaac gtattcactt gcaaccggga gaagaacaaa cggtcaactt tacccttacg
     2281 cctcaagact tgggattatg ggacaagaat aatcagttta cagtagagcc gggaagtttc
     2341 tcggttatgg tgggagcttc ttcacaggac atacggctga aggggagttt tgaggtccaa
     2401 taaataaatc caagacagtc actaaaagca atgtgaggca gcctcttact atttaggcca
     2461 cctcacattc tttttatttc tctttcgtca actaggatag agttataagt tatacttaat
     2521 aacacaaata aaactggcat ctttataagt tatgcttaat aaaactgcca tatctgtttt
     2581 gtatatcaac tataactata aaaagatgaa acttatcaat agccctattt atacagagcg
     2641 tattcgtcgg ttcactgtaa aaggggagga tgtcaaccaa agatattgcg cagttcacca
     2701 atcttactat tcgtggagta gaaacagccc gttaccgaat aagaaagaaa cttgccattc
     2761 ccggaaatat aaatcttgtt gatttcctga ttgactttac ataggaacat ttactgaata
     2821 ttccttctaa tttcacaccc ctattctgtt gggattttct aaagaaactt tatctttgta
     2881 atgtcaacaa ttaaaagaat atggttcgtt ttaatcttgt tatcacctta ctactaatga
     2941 taagcatagc tgtcaaagcc gaactgacca accggatgtt cgatgtcagg catgtaggct
     3001 atgcagaagg ccttagtagc caacgcgttt tttcgattgt cgaggatgga gacggtgcta
     3061 tgtggattgc tacaaaaacc ggaatagaca gatacaacgg tcatacggta aagaactatg
     3121 atttgccggg cagtttctat tatggtgatc ttgccggacg caggctttac ttattgtacg
     3181 acgcacaaca aggactgttc gcctacgacc acaccggacg aatctaccga tattccacca
     3241 tcctggatca ttttgaacaa gtcctccacc tgggacaatt gattcaggaa gaagtcatct
     3301 tgaacaaact ctgtttggat agtgacggaa cctggtggat gggggcggat aaaggactat
     3361 acaagcaaga agcggaccat cgtatagttg ccgtgttgaa aggacaatat gtcaacgaca
     3421 tcgcatttgc cggcgagtcg ctttttgtgg gcacttctaa cggagtctgg caactgtcac
     3481 acgccctgcc ggataagaaa cgccagctgc tggaggggtg gaatgtacaa acattgttct
     3541 gcgacaaacc gaaaaaagaa ctctggatag gcacatttgg cagcggtttg tctgtgatga
     3601 acctcgacac ttccaaagtg cttgcgctgg agggacaagg gagcacgttc cttcatccga
     3661 tacgggcaat tacagactat gatgtacata ccatactcat aggcgtggac ggtggcggtg
     3721 tgtatgcgat agacaaggac accaagaaag cccgtttact gatgaatacc aaagatgaca
     3781 cagatactta cctgcgcgga aacggcgtat atgccgtaac cagagacgat cagggcaaca
     3841 tctggatagg tagttatacg ggaggtgtat ccgtggctat cctgctgaaa catcccattt
     3901 cgatattagc acacgaaaag ggaaataccc attctctcat cagcaacaac gtgaatgata
     3961 tcgaagaaaa cccggatggc aaccaatggt tcgctaccga tgatggaatc agcatccgaa
     4021 acaccctgtc aggcacttgg aaacacgtgc tgaaagaaat cgtaaccatt tctctttgca
     4081 catccggaaa tgggaacgta tgggtaggaa cgtacggaga cggagtgtat ctattggata
     4141 acaacggacg cgtgttacgc catctcacca agcaacaagg gcaattgacc accaattata
     4201 ttttctccgt cagacaagac atggagggag acttatggat aggaggtctg gacggatgcc
     4261 tgatcatgtt tgaaaaagaa aaaggcagca gacagtcttt cgacgtgaat tgggtacagt
     4321 ccattgaacc tatcgaccga aaccgggtag cggtggctac cgtcaacggt tttttcctag
     4381 tggacaaaca tacagggaat atacagcact atgccaattc ccaggaattt cacaatcaga
     4441 atgtcagtgc ttatatcatc tctatgctgt tcaatgacga cggaaccgtg tggctgggaa
     4501 ccgaaggggg aggattgaat ctatatgata tgaaaaaccg gacggtaaag actttcaccg
     4561 ttcaagaggg attgccgtcc aacgatatat atagtttgca gcgagacgac aagaaacgct
     4621 tgtgggtcag caccggaaaa ggaattgcct tgatagacag cctgcgcgtg tcgaacctca
     4681 actatgcagg caatatagac aaggaatata acaaatcctc atttgcccgg ttgatgaacg
     4741 gcgagtttgt gtatggcagc acggatggcg ctgtctttat catgccactc gacatctcaa
     4801 ccgtagacta ctggacgctc ctgcgtttca cggggctgac ggttgattat caaaacgtcc
     4861 aggaagaaga atcgttgaga cccgccatcc atgatatgct tgccgaccgt gcggtacggc
     4921 tcggctataa atacaactcg tttaccgttt cttttgaatc tatcaactat cgtttccagc
     4981 gcgatattgt ctatcagcat attttagagg ggtatgacaa tgactggagc aaaccgtctg
     5041 ccgagggcaa ggcatcctac accaaggtat cgccgggcac ttatcttttt aaagtgcgca
     5101 gcctgcgacg cagcgacgga aagactatct ccgaaagcac cttagaagtg aaagtgagcc
     5161 agccatggtg gaactcgtgg tgggcttgga ctatttacct atttataata ggcttcgttt
     5221 tctatttcat cctgcgctat aagagcaacc agctccaaaa gaaatacgac gaagacaaaa
     5281 tacgtttctt catcgacacg gcgcacgaca ttcgcacgcc ggtaacgctt atcatggcgc
     5341 cactggagga tttgaaccgg gaacaggatc tctcggacaa agcccgttat tacctgaatc
     5401 tggcccatga aagtacccag aaactccatt cgctcatcac acagttgctc gaatttgaaa
     5461 aggtagacgc ccacaagcca tcctcttcat cggttccgct ttgtctgaat gaagttttgc
     5521 tgaaagaagt ctccgtcttc cggtcttttt gcgagaagaa gcagttgaca ctgaatctga
     5581 cccaacccga cgaatccgtt ttcgtttcgg ccgacaaaca cctgatagag atgttactcg
     5641 acaatcttct ttccaatgcc tgcaaataca ccatgcccca gggagaaatc agtctggatt
     5701 tgaaagccac gaaacgcaaa gccatccttt cgttgaaaga taacggaata ggcataccga
     5761 agaaagcgaa aaagcatatc ttctccgata tttacagagc cgaaaatgcc cggcagtcac
     5821 aggaagaagg aaccggattc ggactgttgc aggtgcaacg cattgtaaag atgctgcatg
     5881 gaaaaatcac tttctgttcc gaggagggca agggaactac tttcatcgta acattgccgc
     5941 gaaccaccac cgtagccgaa cccgtgtcgc acgaatcatc cctcgaacac cttgccggca
     6001 catcggataa taacagcccc gaaacggata aaatgaaaga tccggacgac cggaatacat
     6061 tgctcattgt agaagaccac gaaactctcc gtcactacct ccgccagacc tttgaacacc
     6121 tctatcgggt gattgatgtt gccgacggac acgaagctat cgcctgtctc gccaatgaat
     6181 atccggacat catcctctcc gacgtcatga tgcccggcat acggggtgac gagctttgca
     6241 gaatggtcaa ggaaaatcct gacacatcag gtattcccgt cgttctgctg acggcaaagg
     6301 ctaaccacga agcaatagtg gaaggattga agaaaggcgc ggatgattat atccccaaac
     6361 catttagtac agagatactg aaattgaaag tacaaggatt gattgacaat cgaaacaggc
     6421 aacggcagtt tttcatgcgg caagccatcg ctcaagtaga ggcgggcggc aaacgtgacg
     6481 acaatgaaag caatgaaaac aatgaaagta tcgacaacaa aaacgtaacg acagcaagcg
     6541 aaacaatggc cgagggcgac cgccggttta tcatgcaagc tacccggttt gttcttgaac
     6601 atttggatga acccgatttc aacatcaatc tcttatgcca tgaaatggca atgagccgaa
     6661 cactattcta cagtcgcctt aaatcactga cgggaaaagg gccgcaagag tttattcgta
     6721 tcatccggct acaaaaagct gccgaactgc tgaaagaagg taaaagcgta accgatgtcg
     6781 ccaccgaaac cggatttgtc aacacgaagt atttcagttc attgttcaag aaacaattcg
     6841 ggatgcaacc gagtaaatat agtggtaaat agacaagtat taaaggtata gaaatgagct
     6901 aaacgatcat ttgtttttag acataagaac aaaagaacat aaatgctgcg ctttgaaaat
     6961 tatttctgtt gcttattgaa cggctatttt attttttgtt cttatgttct tatgtctgaa
     7021 ttaaattcct aactaaaaac cgcatggttt ggaatcaatt gccactaatg attttattag
     7081 ttatttttaa gcaatcgttt acctattgat agttatttca ttgcctaagg agttttcgtt
     7141 tgactatagt caagcgatag ttcaacatat gtcaagcgtt cgttcaacaa ctgtcaaacg
     7201 aaaactcctt aggcaattga aaaaataata taagcaagag aaagaaataa aaactgcata
     7261 ttgacgagtt attgtcagca atagtatctt gggatcattc cgtacagcaa caatcttcga
     7321 aaaagaatgg gtaagataac gtccgttcga taaaaatcag cagatttgtc agcaatcaaa
     7381 cctaatatgt cagcaatctg accatcgttt cagccggata ttagcatctt tgcaccaagc
     7441 tttacaagta taaagcacat attacgttta acctttaaaa tgctaaaacg atgaaaaaag
     7501 tagcactatt cctattttta tccgtttgct tcgcgcaaca atcctgttcg tcggattctg
     7561 ttggaacgga accggaagaa aatccacaag acattctttt taaagacgat ttcaactttt
     7621 tcgacgaaaa agtatggacg aaagaaactc atgaacccgg ttggaccaac caagagctac
     7681 aggcatacga tgccgctcat gtatcggtag gaaaagacgg ggataaatcg gttctgattc
     7741 ttaccgccga acgcaaaggg aataaaatct attcaggcag gatcaattca aaaggaaaaa
     7801 agagtttcaa gtatcgcaag atagaagcaa gcatcaagct tcccaagact aacggcggac
     7861 tatggcctgc tttctggatg atgggagaca acgacaaaca gtggccggca tgcggggaga
     7921 ttgatattat ggaaatggga gaacagagcg gaatggctgc gggcgattcg gaaaaacaag
     7981 tgaacaccgc cattcactat ggccccagcg cagcggctca cgaacagcaa tactacaaag
     8041 ccaatgttgc caacagccta caagacggca attatcacac ctactccctg gattgggatg
     8101 aaaacaacct gacaatatcc attgacaacg tcaagtttca tacgttcgac attagctcga
     8161 acacatactt tcatgacaac ttctacatcc tgttcaacct cgccgtggga ggtgcgttta
     8221 caggaattac cgatattaat aaactgacgg gcctgaaaga cggtcagaaa gtgaatatgt
     8281 acatcgactg ggtgaaaata ttataggaat cttaaatata catgctatga atatggaaaa
     8341 atgtaagtat ctactgtttt gcggaacact cgccctttgg atggcgggaa gtttccagca
     8401 agtgtatgca gcaacggaac caagttccca agctattcaa caacaaagca acaaggtaac
     8461 cggaaaagtg agcgatgcca caggtcccat cattggggct tccgtagtgg agaaaggaac
     8521 tgccaacgga acgattaccg atctggatgg aaatttcagt ttgaatgtaa aagcgggagc
     8581 tacgctcgtt gtcagctacg tgggttataa atccgaagaa gtaaaagcgg gaagaggtcc
     8641 tttgaacatc accttgaaag aggatgccaa agcattggat gaagtggtag ttaccgccct
     8701 tggcatcaag agagagcgca aagcgttggg ctacggcatt gatgaagtga aaggtgaagc
     8761 cttgaccaaa gcgaaagaga cgaatctcat caactccatg gcaggacgtg tgccaggctt
     8821 ggtagtcagc cagaccgccg gtggtccttc cggttctacg cgcgttattc tgcgaggcag
     8881 taccgaaatg accggcaata accagcctct ttatgtagtg gacggtgtac ctttggacaa
     8941 cactaatttc ggcagtgccg gcacaaacgg aggcttcgac ttgggcgacg gtatttcgag
     9001 catcaatgcc gatgacgtag aaaacatgtc ggtattgaaa ggccctgcgg catctgcact
     9061 ttatggtagc cgtgccagcc acggtgttat cttgattaca accaagcgag ccaacaagga
     9121 taaaatcagc gtggaatata acggaacgct gactttcgac acccaacttg ccaaatggga
     9181 tgaagtgcaa cagatatatg gtatgggaag caacggtact tatagctatg atgccatatc
     9241 caacacaaac aaaagttggg gccccaaagc ggacggttca aacatgttga agtatttcga
     9301 cggcgtagaa cgccctttcc tcattgtccc cgacaatacg tccaacttct tccgcacagg
     9361 tatcaccgcc accaactccg ccatcatagg tgtgaacagc ggaaaaaccg gaattcgctt
     9421 tacctatacg gatatgcgca ataaagacat tgttccccag acgcacatga gccgtgacat
     9481 tttcaacctg cgcgccaata cgtctgcagg aaaggtagac ttggatttca gtgtcaacta
     9541 tacacgggaa gacgtgaaga accgtccggc tctgggcgac agcaagtcca atatcggtaa
     9601 aaacctgatg acccttgcca ccacctacga ccaggaatgg ttgcaaacct atcagactgc
     9661 cgacggcgaa tattccaact ggaacggcat ggatccctac aacgtgaatc cgtactggga
     9721 tatctataag aacttcaaca aatccaagaa agacttgttc cgcatgaacg gcaaggccgt
     9781 atggaacatc gacccacatc tgaaacttca ggcaacgctg ggtgccgaac tcaactggtt
     9841 cacgttcgat gattacaaag cacctaccac tcccggattc gaagccggaa gacttcaaaa
     9901 cagtgctttc cgcaaccgca tgtacaactt tgaagcgttg gctctctaca acaaccattg
     9961 gggtgatttc gatttcaatg ctacattagg cggcaatgta tataaggtga acaaccagac
    10021 caccgttacc accgctcaag acatgaagat acgcgatgtc ccttcattga cgagcttcaa
    10081 cgagatcagt gtagtgcccg gcagttaccg caagcagatt aattcggttt acggagcagt
    10141 gaacgtggga tggaaacaca tgctttacct cgatgctacg ttgcgtggcg accaatcgtc
    10201 tacccttccc actggcaaca acatgtatgt gtatccttct ttctccggta gctttgtatt
    10261 ctccgagctg acaaaactgg gcgacctcct gccttacgga aaggtgcgta tgtcatgggc
    10321 ccaagtaggt agcgataccg atccttatca attgggactc gtctatacga aatccaaata
    10381 tgcttatccc ggatatacca tcggatatat cgataacgga accatcccca acaaagactt
    10441 gaaaccaacc aaaacaaact ccgtggaaat gggattggaa ttgaaattcc tgaagaaccg
    10501 tatcggactg gatttcacct actattctca aatcagtaaa aaccagatta tgggaatggc
    10561 aagttcctgg acaaccggtt acaactatcg cttgattaat gccggcaaga tagaaaacaa
    10621 aggtattgag attgccctta gcacacgacc gattcaaaca cgcgattttt cctgggacat
    10681 taatctgaac ttctccaaaa acagcaacaa agtaaaagaa ctggatggcg aatcagatat
    10741 gtttgaactg gaaaaggcgt cttggctcga cgttcaggtg gccgctaagg taggcgagaa
    10801 ctttggttct attgtaggcc cggacttcca acggaacgaa aagggagata ttctgattga
    10861 cccgcaaacc ggtctgccgc aatatgacaa gagcaaccat gtattaggta atgcctcttg
    10921 ggactggaca ggtggattac tcaccaactt tacctacaag aatctctcgc tggtagcagt
    10981 attcgatgtg aaagtaggcg ccgacctcta ttctatgtct gcccgtgctg cttacgaatc
    11041 gggtaaaagt ccggaaacat tggcaggacg cgacgcctgg tatcgctcgg aagaagaaag
    11101 attggcagcc ggcattgcaa aaggagccga taactggaag ccgacaggcg gattcgttgc
    11161 tccgggtgtc atcgacaacg gtgatggaac atatcgtccc aacgacatct acatcaatcc
    11221 ggaagactac tggatgagcg tttgccgtaa tgcaccttct atgtttattt acgacaactc
    11281 atacgtgaaa tgccgtgagc tgacgttgag ttacaatgta cccaaatcct ggctgaagaa
    11341 tgtagtaagc ggactgaccg tttcgttcgt tgcccgcaat ccgttcatcg tatggaagaa
    11401 tatcccgaat atcgacccgg attccaacta caacaatacc accggtatgg gacttgaata
    11461 cggttcgttg ccttcacgca gaagctatgg ttttaatgta aatgtgaaat tctaaaaaga
    11521 tatatcatga gacaatctaa atacatcaca atcatcacga tggcatgtgc cctgtttttc
    11581 gcttcttgca gcgatgaata catggaaaac atgaataccg acccttccaa ggccgctacc
    11641 atcgacccga atgcgcagct caccactgcc caactgcaaa cgtacggaga ccttagtatg
    11701 atggaaatct accgtaacta ccattatgca ttcacccaac aactgatggg atgttggaac
    11761 accaccaact acggcggacg ccatacgcta gacaataatg aaatgagccg tatctggaca
    11821 tcgttctaca ctcaatccct gaagaatatc attgatgctc aatatcgcac agccgaagat
    11881 gcagagaaag tgaatatcaa ctctgtactc cgcatttatc gggtttatct tatgtctatc
    11941 atcaccgaca cttacggaga cgctcctttc agtgaagccg gcctgggatt cctcgaagga
    12001 aagttcaatc cgaagtatga caaacaggaa gatatttaca acgctttctt tctggagctg
    12061 gaagatgccg tcaataaaat cgatccgacc aaagataaag tgacaggtga cctcatctat
    12121 gccggtgatg taactaaatg gcaacaactg gcaaactcgc ttcgcctacg ttttgccatg
    12181 cgaatatcca gtgtcaatcc tacaaaggca caaacggaat ttgaaaacgc tttggctgcc
    12241 aatgggggtg tgataacgga cgcctcaagc gatgcgctca tcaaatacat gacaatcgca
    12301 tttagtttcg gacaagaagc ttactctgat tatcgcggaa attcattgtc acagttgttg
    12361 ttcggcaacg accccgctaa taatccaagt tacctctgtt ccactttctt taatcagtta
    12421 tacaattccg gtgacccccg tacattcaaa atttcccgtt gttattatga cgggctgatg
    12481 agtgccacca gtcccgacaa tcgtgtcgac atcacccaag agatgattga aaaagggatt
    12541 gctttcagtc cgcgcgaccc aggtgcctac tcgtgggaac catggcctac agggtacgac
    12601 agcgatattt gtgcggaatt agccgttaac aacccttccg ttacagcaac catggctcgt
    12661 gaagtggaac ccaaacttgc caataatttc ctaaaaagcg acaatccggg cgtagtgatg
    12721 acctctgcag aagtgaagtt cctgatggcg gaagctaccg tgaaaaaatg gaatgtcggc
    12781 agtgtgtcag cagaagatct ttacaagcaa ggagtacgtg ctgctattga tttcctgaca
    12841 gacaactacg gttgcacggc tactactgat gcagagtttg atgcattcat tcaagataaa
    12901 ggggcgttcg gacatacgga caatcagaaa cttgaagcta tcaatacaca ggcctggatt
    12961 cttcacttca ccaatcctgc cgaatgttgg gcaaacgtgc gtcgttccgg ttatccgaag
    13021 ttgaaatcac cggcagaata tgggttcgga caatacctca ccggtggaac ggaaattccg
    13081 gtacgtctat gctatcctgt attggaatct tcctataata aaaagagcta caatgaagcc
    13141 atcgagcgca tgggaggaac agacaattgg cacagccttc tgtggtggga tactgaaaac
    13201 taactattaa acaatcatcc attatgaaaa agatatatat tgcactattt gccctactcg
    13261 ctgtaggctc cacatttact gcatgcaccg aggaagaacc gttcgctacg gtgacagaaa
    13321 atgatgatcc gcatatcctt gccccggtat tccctgacag aacgaacggc caattggcta
    13381 cattcgccaa catcagtcgg gatgcgaact tatccatcgc gctgaccgtg actccgaaag
    13441 attacaccac agtaacctgg ttcattgatg ggcaggaagt agaatcgggt accgactccg
    13501 acaaagaaat caaccgtagt ctgaaagccg gtacgtataa tttgaaaata gaagtggaaa
    13561 ctgtgaaagg gaagaagact tcccgtgaag gattggtggt ggtcaatccg ttggctgatg
    13621 accctcaatc gaaagaagta gcctttgaga gaattgtatc tcccggtaag actgcccgtt
    13681 tatatggcag taatttacag aacgtaacag ccatcctctt gggaggaaac acgatcaccg
    13741 atcctactta tgttgaatcg gcagacgaga attatctgga atacaccatt ccgacaggcg
    13801 taagcgaagg cgattaccgt atcgttctgc aagatgccga cggcaatcaa tatggagccg
    13861 acatggtgaa agtaaccaat gcttcccttg tcatttcggg agctaaccgg gctactgcca
    13921 acgtggattg gaccatttcc ggcatcaatc tcgaaaacat cgcttctcta accattggcg
    13981 ggcaaacggt atctcaattc agcaaccaat cttctacaga gattacgctg acttgtccgg
    14041 atttgtctga tggaagctat acgatgacag gcaagacccg cagcggagag gctgtgcagt
    14101 tcttgaacga taatattacg actaccgaac agactgtgac cgtatctacc gaaataacgc
    14161 tttggtcagg acaccattac gtttcgtggg ataagccgga cggtgatccc aacaaaactt
    14221 ttggtttgat tccaatggat gtatttgctg gtatcacagc cgggtcgaca ctgaaagtag
    14281 tctactccat agaacctact gccgaatatc ataaaatgca gcttgccaca ggctattgga
    14341 caggcttggc aagtgagatg gaatttacgg aaaacggtga atatacactg atactaacac
    14401 aagacatgtt gaataagatt caagctgaag ccggattctt atgtgtagga catggctatt
    14461 atgtagattt ggtaaccgtg aaataatgtt cctaagtaag tttaaaaatc attcatacca
    14521 taagtatctg tcattcttcg ggttaaagcc ctctgaatga cagattacat aaacgatgct
    14581 acttaaaaac aaatcataat gaaactaaga aatattatat taatgaccgc atctatcgca
    14641 atgactgcct gttccaaaca ggcagttccc actgccattc ctgaagacgc taaaatagaa
    14701 caacaagtgg aagagcttct atcaaagatg gatcttgacg ccaagatagg gcaaatgacc
    14761 gagcttgcta ttgatgtatt aggagagacg ataaatggag aattccaatt ggacgaggca
    14821 aaactccaca aagcgattgc tgaatacaag gtaggttcgt ttctcaatgc tcccggcccg
    14881 gtagcacaaa gccctgaaaa gtggaacgag attatcggtc gaatacaaga actgtcgatg
    14941 gcggagattg gtattccatg tatctacggc ctggatcaga atcatggtac tacctataca
    15001 ttgggcggca cgctctttcc tcaaaatatc aatatgggtg ctgccttcaa tccggatttg
    15061 acctacgaag cggcacgtgt aacggcttat gaaacaaggg ctagcaattg tccctggaca
    15121 tactccccca ctgtcgatat ggcacgtgat ccccgttggc cgcgtgtatg ggaaaattat
    15181 ggagaagact gtttagtcaa tgccattatg ggcagcactg ctgtccgagg cttccaagga
    15241 gatgatccta accatattcc cgccgaccga atcgccacct ccgtgaaaca ttacatggga
    15301 tacagcatgc cacgtaccgg caaggaccgc acaccggctt atatatctgt ttccgaactg
    15361 cgtgaaaaat gttttgcacc gttcagggct tgtgtggaag caggtgcact gactataatg
    15421 gtcaacagtg gttccatcaa cggaaagcct gtgcacgccg accgcgaact ccttacacaa
    15481 tggctgaaag aagacttagg atgggacgga atgttaatca ccgactgggc ggacatcaac
    15541 aatctttata cccgcgaaca tgtggcagca aacaagaaag aagccatcga aatggcaatc
    15601 aatgcaggta tagacatggc tatggaaccg tatgatctca attattgtac actactaaaa
    15661 gagttagtgc aagagaagaa aatacccatg agccgtattg acgatgccgt ccgccgggtg
    15721 cttagactta aattccgtct gggtctgttc gatcatccga acactttatt gaaagattat
    15781 cctctcttcg gcagcaagga gcatgcactt atcgcacttc atgcagctga agaatcggaa
    15841 gtattgctaa aaaataaaga taatattctt ccgcttcctc aagggaaaaa gctactggta
    15901 accggtccga acgccaactc tatgcgttgc ttgaacggcg gttggagcta ttcgtggcaa
    15961 ggacatctga ccgatagatt tgccgacaaa tataacacca tttacgaagc aatctgcaac
    16021 aaattcggag ccgatcatgt ccgtctggaa cagggcgtaa cctacaaacc cgaaggtgct
    16081 tacatggaag aaaatgaacc ggagattgag aaagctgtgg ccgccgcccg caacgtggat
    16141 attattatcg cctgcatcgg tgagaattca tattgcgaaa cacccggtaa tctttccgaa
    16201 cttgccatct ctgccagcca aagcaaactg gtaaaggcac ttgccgctac aggaaaaccg
    16261 atcatcctga tactcaatga gggtcgtccc cgcattatca acgagttgga gccattggct
    16321 gatgcagtta ttgacattct attacccgga aactatggtg gcgacgcatt ggcgaacatt
    16381 ctggcaggag acgtgaaccc cagtgccaag atgccttaca catatccgcg acacgaagca
    16441 gcactgacta cctacgatta tcgggtgagt gaagaaatgg acaaaatgga aggagcttat
    16501 gactacaatg cagtagtctc cgttcaatgg cctttcggat acggattgag ttacaccact
    16561 ttcgagtaca gcaacttcca aacggacaaa tcttcgttta ccgcaggaga tgatttgcac
    16621 ttttccatag atgtaaccaa taccggtaaa tatgccggaa aagaagttgt catgctattc
    16681 agcagtgatc ttgtggcttc gcttactccc gaaaaccgcc ggttacgagc cttcaaaaag
    16741 gtggaactgc aaccgggcga aacccagact atcactctat ccatcaaagg cagcgacttg
    16801 gcttttgtca attccgacgg gcaatgggta ctggaacaag gggatttccg tatgcaatgc
    16861 ggaaatcaaa cactgaatat tatatgcaag taa
//
