LOCUS       AB812045               20808 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: H509a.
ACCESSION   AB812045
VERSION     AB812045.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20808)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20808
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H509a"
                     /db_xref="taxon:562"
                     /note="serogroup:O100"
     gene            518..1909
                     /gene="wcaM"
     CDS             518..1909
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ01447.1"
                     /translation="MLKKITRRSFVSSLSVLAAMPLLSPRVARAATGKTVSVNQYTNND
                     WIAAFKQAFNEGDTVVVPAGLTCKNINTGIFIPDGKTLLIRGALTGNGRGRFVLQEGSK
                     VIGEGEGRTENITLDVRGSDCVIKGLAMSGFGPVTQIYIGGKKPSVMRNLVIDNIRVSQ
                     ANYAILRQGFHNQVDGARITNSKFSHLQGDAIEWNVAINDRNILISDHVIDNINCTNGK
                     INWGIGIGLAGSTYDNDYPEKQTVKNFVVANITGSNCRQLVHVENGKHFIIRNIKAKNI
                     TPDFSKKAGIDNATVAIYGCDNFVIDNVDMVNSAGMLIGYGVIKGDYLSIPQNFKLNDI
                     RLDNSQLAYKLRGIQISSGNATSFVAITNVEMQRATLELHNKPQHLFLRNINVMQEAAI
                     GPALKLNFDLRKDVRGKFMAKDETLLSLANIKAVNEKGQSSVDIDRVDQHVVNTERLNF
                     ALPHR"
     gene            2085..2981
                     /gene="galF"
     CDS             2085..2981
                     /gene="galF"
                     /note="O100_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ01448.1"
                     /translation="MINLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIV
                     AAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQSICPPGVTIMNVRQ
                     AQPLGLGHSILCARPVVGDNPFIVVLPDIIIDTASADPLRYNLAAMVARFNETGRSQVL
                     AKRMKGDLSEYSVIQTKEALETEGQVSRIVEFIEKPDQPQTLDSDLMAVGRYVLNADIW
                     AELGKTKPGAWDRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKLGYMQAFVNYGLRNL
                     KEGAKFRSRIEKLLAND"
     gene            3321..4403
                     /gene="rmlB"
     CDS             3321..4403
                     /gene="rmlB"
                     /note="O100_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ01449.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIKNTQDEVVNVDKLTYAGNLESLTE
                     VSDSARYVFEHADICDKSAMDRIFAEHKPDAVMHLAAESHVDRSITGPAAFIETNIVGT
                     YVLLEAARAYWSTLDDVAKKAFRFHHISTDEVYGDLPHPDEHPVSTDLPLFTETTAYAP
                     SSPYSASKASSDHLVRAWLRTYGFPTIVTNCSNNYGPYHFPEKLIPLVILNALDGKPLP
                     IYGKGDQIRDWLYVEDHARALYTVVTQGKPGETYNIGGHNEKKNLEVVHTICDLLDEIV
                     PKEGSYRDQIMYVADRPGHDRRYAIDAHKIAAELGWKPAETFESGIRKTVEWYLSNQDW
                     VNNVKSGAYKTWIEQNYGER"
     gene            4406..5305
                     /gene="rmlD"
     CDS             4406..5305
                     /gene="rmlD"
                     /note="O100_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ01450.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSKEYCGDFSNPEG
                     IAETVRAIKPDVIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKEAAKIGAWVVHYST
                     DYVFPGDGDKPWRETDATAPLNVYGQTKRDGEKALQAYCPNHLIFRTSWVYAGKGNNFA
                     KTMLRLAKERKELSVINDQVGAPTGAELLADCTAHAIRVAMVKPEVAGLYHLVASDTTT
                     WYDYAALVFDEARKAGIELAIEKLNAVPTSAYPTPARRPQNSRLSTEKFQHNFGLVLPA
                     WDVGVKRMLAELFTTKSL"
     gene            5358..6236
                     /gene="rmlA"
     CDS             5358..6236
                     /gene="rmlA"
                     /note="O100_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ01451.1"
                     /translation="MATRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLM
                     LAGIKDILIISTPQDTPRFEQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGNDS
                     CALVLGDNIFYGHDLPKQLEAAVSKGNGATVFAYHVNDPERYGVVEFDKNGTAISLEEK
                     PLEPKSNYAVTGLYFYDNDVVEMAKNLKPSARGELEITDINRIYLEQGRLSVAMMGRGY
                     AWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKKLAEPLKKNAY
                     GQYLLKMIKGY"
     gene            6240..6788
                     /gene="rmlC"
     CDS             6240..6788
                     /gene="rmlC"
                     /note="O100_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ01452.1"
                     /translation="MNVIKTDIPDVLIFEPKVFGDDRGFFFESFSQKVFEEAVGRKVEF
                     VQDNHSKSCKGVLRGLHYQLEPYAQGKLVRCVAGEVFDVAVDIRKSSPTFGKWVGVNLS
                     AENKRQLWIPEGFAHGFLVLSNIAEFVYKTTNYYHPESDRGLIWNDRDIGIVWGDTDNV
                     LLSEKDQKQPSLTELLNQQ"
     CDS             6790..7194
                     /note="O100_06"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerol-3-phosphate cytidyltransferase"
                     /protein_id="BAQ01453.1"
                     /translation="MCCTMKRIITFGTFDVFHVGHINIIERAKKLGDYLIVGVSSDELN
                     FSKKQRYPIYNQTDRLKIISSMKCVDEVFIEESLELKLEYIKKYKADILVMGDDWTGRF
                     DWVKTDCEVIYLPRTPSVSTTEIIEIVKSI"
     gene            7207..8448
                     /gene="wzx"
     CDS             7207..8448
                     /gene="wzx"
                     /note="O100_07"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ01454.1"
                     /translation="MPKKNVVENIIFLSIIQFANYLAPLMVLPFLSRTLGVEGFGLIMV
                     AFSACTLCFLLTDFGFNLSAPYWIARNSNYRNRVSRTIGAIFLIKFIILLIIGLILFLY
                     VLFLTSNTMHMRLMYTIIYCIAIAQAFQPVWFFQGVEKMKNVTIFMVTAKLSYLILIFL
                     FVRNKEDDLLVLLCFFISNFIATIIGVGLIWGAGYKIMIPTKKIIADTFKASSSFFLSR
                     LAVGVYTNASTLIVGAASGVVQAGLYSSAEKLYQAGQNLTSPISQALYPYVARTGNKNI
                     LFKTILLLLIPMILGCSICFIYAAEIIKLIYGASFVNAQHVLRIFLIISIITFVSINLG
                     YPAFAAMGRVNLANYTVMLGGIVQVLLLAILYTINSINAVNVALSVLTTEIIVLAVRIL
                     LLIKPNINTHEEYR"
     CDS             8432..9628
                     /note="O100_08"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycerophosphotransferase"
                     /protein_id="BAQ01455.1"
                     /translation="MKNIVKIPVKFVAVCARMLSITLACLIPKEKKLWVFGGWYGQRIS
                     DNPKYLLQYVNKYHAKNIRAVWIYKNANVKAEALKLGIEAYHYKSIKGKLIQLRAGLVL
                     FTHTIHTDLNSKCISWNTKRIQMWHGIPLKKIGFDDNFTASKLKKSKLYRFTLNDINSY
                     VLSSGNAVSKIFQSAFDESLGKMAETGFPRNDVFFNKQHQKISGKYNVLYMPTLRAGYG
                     ATFNLLDKRYDFQFEEIDSFLKEHDITLTLRIHPANNPDAKMVELIAASDSIKMSSSDD
                     VYDEIGMYDCLITDYSSIMFDFALSHKPIIFAAFDIKDYLRDDRGMYFNYEDIASNNIA
                     FSWQDVMFSLKENINVREHQDYKFLLQFHDDQNLLGKEHYYSRKVYEFLIEKLNIHVS"
     gene            9662..10831
                     /gene="wzy"
     CDS             9662..10831
                     /gene="wzy"
                     /note="O100_09"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="BAQ01456.1"
                     /translation="MAFIRFVNFLIIFFISIDMGGELGIRNVSFLLLVLLIAYYIVTCK
                     KIKFRLPYVLLIILFLGYPVASLFIGMSNNFDADTGISQISIFVFAFLYFLKRIIEEDN
                     NLPLMPIQYFNNAMLIISLFYVLMLISYQFFPSIFNSIALYIHDRGAGFAGVRTENGVG
                     FANIYLKSSLFLIFTYCCFLKRNTIKAAIIILATVITTSKALLLTEVLLLVTKLKGRLI
                     SVVVFVSALLLFIAIYFDEIMVVFNYMNETLQGNSETYLVRVHHFEDLVALFSENPINF
                     LFGFGAGSSFFSSYYGKYIFNIELDHLNAIRKFGLIWFLSFMWLVFFNIIQLVRLKRNE
                     LALGLFLSFVLAGTNPVLLSPIFFILLIECHLLTLKVPCSTSGLHNSKV"
     CDS             10840..11781
                     /note="O100_10"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01457.1"
                     /translation="MFNKSKKLAILLSSYNGEQFIEQQLQSLIDMKADFIFDIHIRDDG
                     SSDKTCETIKKFSQKHANIHLYEENNVGVIASFLWLVEKVSGYDYYAFCDQDDFWQPLK
                     ALAAIDKFEKHEEITPLVYCSAYDYVDQNLNFIGRFTSKSNFSPSNLLIENCAPGCTML
                     FNSALREKYLSISAANISNRVVMHDWLFLLLGLHFGMVIYDRNSYLLYRQHANNVIGKK
                     SGLLPIFRSKYKQFIKECKRPQHLLYLQNELFSDITSGQVNSLTHKLSCSFVSAQRNFY
                     SRAKFAFSGKIKRIRKVDDLIFKILFVFGYYK"
     CDS             11788..12936
                     /note="O100_11"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ01458.1"
                     /translation="MESMSQLKKLHIVLVGNTLWSVYNFRRGLIQSFMSNGHRVTIVGP
                     KDEFTEKLEGLGCDVVDIPISSQGKNPFIDMLLINRLRVVYKRIKPDFVFHYTIKPNIY
                     GSIAAGLSRTKSIAITTGLGYVFNNSSFFTHIISHLYCFAFKFAKEVWFLNEDDRNVFI
                     QRGIISPGKTHILDGEGVDTSFFIPRAKPISHKKSKVTFLLVARMLWDKGVGIYVDAAR
                     KLKEQYPDTEFQLLGACDVDNPSAIPRDIIDNWHEEGVVNYLGMTNDVRTVVSQADCIV
                     LPSYYREGVPRTLMEAASMGKPVLTTDNVGCRNVVIEAQTGFLCKTKDVDSLVDAMNKI
                     LHLTPEERSEMGLNGRDYMISRFDERVIIADYYNAIQKYVEV"
     gene            13083..14489
                     /gene="gnd"
     CDS             13083..14489
                     /gene="gnd"
                     /note="O100_12"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ01459.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSRDKTEEVIAE
                     NPGKKLVPFYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLEKGDIIIDGGNTF
                     FQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVA
                     EDGEPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAETFTEW
                     NKGELNSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLIT
                     ESVFARYISSLKDQRVAASKVLSGPQAKPAGDKAEFVEKVRRALYLGKIVSYAQGFSQL
                     RAASDENNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPYFKKIADE
                     YQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRTDK
                     EGVFHTEWME"
     gene            14713..15879
                     /gene="ugd"
     CDS             14713..15879
                     /gene="ugd"
                     /note="O100_13"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ01460.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQSKVDMLNQKKSPI
                     VDKEIQDYLTHKELNFRATTDKEDAYRDADYVIIATPTDYDPKTNYFNTSTVEAVIKDV
                     IAINPNAVMVIKSTIPVGFTKSIKEELGIDNVFFSPEFLREGRALYDNLHPSRIVIGER
                     SERAESFAALLQEGAIKKDIPVLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLG
                     LNTRQIIEGVCLDPRIGNHYKNPSFGYGGYCLPKDTKQLLANYQAVPNNLISAIVDANR
                     TRKDFISDSILARQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVQVIIYEPAMQ
                     EDEFFHSRVIRDLDAFKQEADVIISNRMAEELADVADKVYTRDLFGSD"
     CDS             complement(15931..16992)
                     /note="O100_14"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotide sugar epimerase"
                     /protein_id="BAQ01461.1"
                     /translation="MPVHLSLRHRQERRVNEEDMKFLVTGAAGFIGSHVSKRLLDAGHQ
                     VVGIDNLNDYYDVNLKLARLDLLKSGTFTFHKMELADREAMAALFASEKFERVIHLAAQ
                     AGVRYSLENPHAYADANLDGHLNVLEGCCHNKVQHLLYASSSSVYGLNRKMPFSTDDSV
                     DHPVSLYAATKKANELMSYTYSHLYNLPTTGLRFFTVYGPWGRPDMALFKFTKAMIEGK
                     SIDVYNYGKMKRDFTYIDDIAEAILRLQDVIPQADENWTVETGSPATSSAPYRVYNIGN
                     SSPVELMDYITALEEALGKEAEKNMMPIQPGDVLETSADTKALYDVIGFKPQTSVKDGV
                     KNFVEWYRAFYKV"
     CDS             complement(17020..17838)
                     /note="O100_15"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase of IS600"
                     /protein_id="BAQ01462.1"
                     /translation="MCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETY
                     GTRRLQTELAENGIIVGRDRLARLRKELRLRCKQKRKFRATTNSNHNLPVAPNLLNQTF
                     APTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMALR
                     SQRPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNES
                     LSHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
     CDS             complement(17923..19074)
                     /note="O100_16"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase of IS30D"
                     /protein_id="BAQ01463.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDTG
                     GIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRRYY
                     KAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQKTLR
                     ISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPIHERS
                     RNVDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALTDKFLS
                     LPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIRQYFPKK
                     TCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
     gene            19617..20597
                     /gene="wzz"
     CDS             19617..20597
                     /gene="wzz"
                     /note="O100_18"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ01464.1"
                     /translation="MTQNNNTPVNSSNGPEQIDLLDLVLQLWRGKWVIGAFVAVFIIIA
                     GIYIIVAKEKWTSSAIISQPDAAQITTYANALNILYGSAAPSMQDIQNRAIGRFNSSFS
                     ALAWALENQEMPEKLTIDTTVKGQALPLSVTYQGESAEAAQKQLAQYIQQVDEQTAKEL
                     ALDLKDNIKQQITSLNDSLENQEKVAQEQKDLRIKQISEALKNAEAAKITTPQIQQTQD
                     VTQETMFLLGSEALKSMIDNEASRPLVFSGTYYQTKQNLLDIEKLNVKPDTIHVYRYVM
                     KPDLPIRRDSPKKAIALILAVLLGAIIGSGVVLGRNALRNYKPKV"
     gene            complement(20636..>20808)
                     /gene="hisI"
     CDS             complement(20636..>20808)
                     /gene="hisI"
                     /codon_start=3
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ01465.1"
                     /translation="QKVGEEGVETALAATVHDREELTNEASDLMYHLLVLLQDQELDLT
                     AVIENLRKRHK"
ORIGIN
        1 ggcgattgaa gcctgccgcc agctcaaggc gcgcggggtg gatttccgtt atcgcattct
       61 cggtatcggc ccgtgggagc gtcgtctgcg tacgcttatt gaacagtatg agctggaaac
      121 gcacgtggag atgccgggct ttaagccgag ccacgaggtg aaggccatgc tcgatgaagc
      181 cgacgtgttt ctgctgccgt ccgttaccgg cgccgatggc gacatggaag gcataccggt
      241 ggcgctgatg gaggcgatgg cggtggggat tccggtggta tcgacgctgc acagcgggat
      301 ccctgagctg atcaagtcag atcattccgg ctggctggtc cccgaaaata acgccatggc
      361 cctggccgat cggctggccg cgtttagcga tatcgaccag caggcgctgg agcccgtgct
      421 gcacaatgcc cgacaaaaag tcgaggcaga ttttaaccag caggtgatca atcgccagtt
      481 agcgagcctg ctgcaaacgt tgtaacgccg aggttgtatg ctgaaaaaga ttacccgacg
      541 cagctttgtc tcttctctgt ccgtcctggc ggcaatgccg ctactgtcgc cccgcgttgc
      601 gcgggcggca accggcaaga cggtctctgt aaatcagtac actaacaacg actggatcgc
      661 cgcctttaag caggcgttta acgaaggcga caccgtcgta gtgcctgcag ggctcacctg
      721 caaaaacatc aacacgggca ttttcattcc tgacggcaaa acgctgctga ttcgcggggc
      781 gttaaccggc aatggccggg ggcgctttgt cctgcaggag ggcagcaaag tcatcggtga
      841 gggcgaaggc cgtaccgaaa acattaccct tgacgttcgt ggctctgact gtgtcatcaa
      901 agggctggcg atgagcggat ttggcccggt aacgcaaatc tacattggcg gcaaaaagcc
      961 cagcgtgatg cgtaatctgg tcattgataa catccgcgtg agccaggcca attacgccat
     1021 cctgcgccag gggtttcaca accaggtgga tggcgcccgc atcaccaaca gcaaattcag
     1081 ccacctgcag ggcgatgcga tcgagtggaa tgtggccatc aatgaccgca atattctgat
     1141 ctccgaccat gtgatcgaca acatcaactg caccaacggg aagattaact gggggattgg
     1201 tattggcctt gcgggcagta cctacgacaa cgactacccg gaaaagcaga ccgtgaagaa
     1261 ctttgtggtt gccaatatca ccggcagcaa ctgccgccag ctggtgcacg ttgagaacgg
     1321 taaacacttt attatccgca atattaaggc caaaaatatt acgcctgatt tcagtaaaaa
     1381 ggcgggaata gacaatgcca cggtagcaat ttatggctgt gataatttcg ttattgataa
     1441 tgtcgatatg gtcaatagtg ccggcatgtt aatcggttac ggcgtgatta aaggtgacta
     1501 cctgtcgatt ccgcagaact tcaagcttaa cgatattcgt ctggataata gccagcttgc
     1561 ctataagctg cgcggcatac aaatttcatc cggtaatgcg acctcgtttg tggccatcac
     1621 caacgtcgag atgcagcgcg cgacgcttga actgcataac aaacctcagc accttttctt
     1681 acgcaatatc aacgtgatgc aggaagcagc aatcggaccc gcgctgaagc tgaacttcga
     1741 cctgcgtaag gatgtgcggg gtaagtttat ggcgaaagac gagacgttgc tgtcactggc
     1801 aaacatcaaa gcagtgaatg agaaagggca gagctcggtg gatattgacc gggtggatca
     1861 gcatgtggtg aatacggaac ggctgaattt tgcgctgccg cacagataat cgttagtggg
     1921 ctttttgcga ctattcctgg cacggaatcg cattctattc agattacaac tactgtaatt
     1981 tgtggtgcta aggcgtaata tcattacagg attacggcaa atcatactgg cgaaaacagg
     2041 tttaagagct ataattcgtc aaccatttta aggtggaaga aataatgatt aatttgaaag
     2101 cagtcattcc ggtagccgga ctgggcatgc atatgctgcc agccacaaaa gccattccta
     2161 aagagatgct accgatcgtc gacaagccga tgattcaata catcgtcgac gagattgttg
     2221 ctgcagggat caaagaaatc gttctggtta cgcactcgtc caagaatgcg gttgaaaacc
     2281 acttcgacac ctcttacgaa ctcgaagcgc tgctggagca gcgtgttaaa cgtcaattgc
     2341 tggcggaagt gcagtctatt tgtcctcctg gcgtgaccat catgaacgtc cgtcaggcgc
     2401 aaccgctggg cctgggtcac tccatcctgt gtgctcgtcc ggtcgtgggc gacaacccgt
     2461 tcatcgtggt cctgcctgat atcatcatcg ataccgcttc tgcggatccg ctgcgctaca
     2521 acctggcggc gatggtggcg cgtttcaacg aaacaggccg cagccaggtg ctggcgaaac
     2581 gcatgaaagg cgatctctct gagtactctg taatccagac taaagaagcg ctggagacag
     2641 aagggcaggt gagccgcatc gttgagttta tcgaaaagcc ggatcagcca cagacgctgg
     2701 attccgacct catggcggtt ggccgttatg tcctgaacgc ggatatctgg gccgagctgg
     2761 gaaaaaccaa accaggcgcc tgggaccgta tccagttgac cgatgcgatt gccgagctgg
     2821 cgaaaaagca gtctgttgac gcgatgctga tgaccggtga gagctacgac tgcggtaaaa
     2881 agctgggcta tatgcaggca tttgtgaact atggactgcg taacctgaag gaaggggcga
     2941 agttcagaag ccggattgag aagttgttag ctaacgactg attttatctt acttgattta
     3001 cgcaagcggc agtcatcatt gggtatgttg caacataacc aaaatgatga ctgccgtttt
     3061 tcgttattaa ttctaatgat aacatggatt ttggtcagat ttgtgacgat ttgtgcttgt
     3121 ttctgaggtc atttaggacg acaattaacg ccagtttttg tctgaatcca gaccagaaaa
     3181 atcatttatt caaacttcgc tcagtgcact ggtagctgtt aagccagcgg cggtagcgtg
     3241 caaaatttct gaagccgata ttaattaccc ggtatcagaa cgccaatatc tcgacaaatt
     3301 caatagacgg aacagatcac gtgaaaattc ttgtgacggg cggggccggc tttatcggct
     3361 cagcagtggt acgacatatt attaaaaata cccaggatga agtcgtcaat gtggataaac
     3421 tgacgtatgc cggtaacctt gagtcgctta ccgaagtgag tgatagcgcc agatatgtct
     3481 ttgagcatgc ggacatttgc gacaagagtg ccatggatcg tatctttgct gagcataagc
     3541 cggatgccgt tatgcacctg gcggctgaga gtcatgtcga tcgttccatc accggcccgg
     3601 ccgcgtttat tgaaaccaat atcgtcggta cctatgtatt gcttgaagcg gctcgtgctt
     3661 actggtccac tttagatgat gtagcgaaga aggcgtttcg tttccatcat atctcgaccg
     3721 atgaagtgta tggcgatttg ccgcacccgg acgagcatcc ggtttctacc gatctgccgc
     3781 tctttaccga aaccacagct tatgcgccaa gcagcccgta ttctgcttca aaagcttcca
     3841 gcgatcatct ggttcgcgcc tggctgcgta cctatgggtt cccaaccatc gtcactaact
     3901 gctccaataa ctacggcccg tatcatttcc ctgagaaact gatcccgctg gtcatcctga
     3961 atgcgctcga tggcaaacca ctgccaattt atggcaaagg tgaccagatc cgcgactggt
     4021 tgtatgttga agatcatgct cgtgcgctct acaccgtcgt aacccagggt aagccgggtg
     4081 aaacttacaa cattggtggt cataacgaga agaaaaacct cgaggtggtt cataccattt
     4141 gcgatctgct ggatgaaatt gttccgaaag agggctctta tcgcgaccag atcatgtatg
     4201 ttgccgatcg tccaggccac gatcgccgct atgctatcga cgcacataag attgccgctg
     4261 aattgggttg gaagcctgca gaaacatttg aaagtggcat tcgtaagaca gtggaatggt
     4321 atttgagtaa ccaggactgg gttaacaacg ttaaaagcgg tgcctataag acctggatcg
     4381 aacagaacta cggagaacga taactatgaa tattcttctg ttcggcaaga cagggcaggt
     4441 gggttgggaa cttcagcgcg cactcgctcc attaggtaat ttaattgccc ttgatgtgca
     4501 ttccaaagag tattgtggtg attttagcaa tccggaaggg attgctgaga ctgtccgtgc
     4561 tatcaaacct gatgtgatcg ttaacgcagc agctcacact gctgtagata aagcagaatc
     4621 tgagccagag tttgcgcagt tactgaacgc aaccagcgtt gaagctattg cgaaggaagc
     4681 tgcaaaaatt ggggcctggg ttgttcatta ttcaacagat tacgtttttc cgggcgatgg
     4741 cgataaacca tggcgtgaaa cggatgcaac agcgcctttg aatgtttatg ggcagactaa
     4801 acgtgatggt gaaaaagcgc tgcaagcata ttgccctaac catcttattt tccgtaccag
     4861 ctgggtctac gcgggtaaag gtaacaattt cgcgaaaacc atgctgcgtc tggcgaaaga
     4921 gcgtaaagaa ctttctgtta tcaacgatca ggttggtgca cctacaggtg cagaattact
     4981 ggcagactgt accgcgcatg ctattcgtgt agcgatggta aaaccagaag tggctggtct
     5041 ttatcacttg gtagcatccg atacgacaac ctggtatgac tatgcagcac tggtatttga
     5101 tgaagccaga aaggcaggca tcgaactggc gattgaaaag ctcaacgctg tgccgacaag
     5161 cgcttacccg acacctgctc gtcggccgca gaattcgcgg ttaagtacag agaaattcca
     5221 gcataacttt ggtctggtat tgcccgcatg ggatgttggc gtgaagcgca tgctcgctga
     5281 gctttttacc actaaatcac tttaaccatt agataaatgc ccggattcgg gcattttgcg
     5341 tttacagaga aattataatg gctacgcgta aaggtattat tcttgctggt ggatccggca
     5401 ctcgtctcta ccctgtgacc atggcggtga gtaaacaact gctgcccatt tacgacaaac
     5461 caatgattta ctatccgctg tctacgctga tgctggcagg gattaaagac attctgatca
     5521 tcagtacgcc acaggatacc ccgcgctttg aacagcttct gggcgacggc agtcagtggg
     5581 ggttaaacct tcagtataaa gtacagccaa gccctgatgg actggctcag gcctttatca
     5641 ttggcgaaga gttcattggt aacgacagct gtgcgttagt gctgggcgat aatattttct
     5701 acggccatga cctgcctaaa cagctggaag ccgcagtgag taaaggcaac ggtgcaactg
     5761 ttttcgccta tcacgtcaac gatcctgaac gttatggtgt ggtcgagttc gacaaaaatg
     5821 gtacggccat cagtctggaa gagaagccgc tggaacctaa aagcaactat gctgtaacgg
     5881 gtctctattt ctacgacaat gatgtagtgg aaatggcgaa gaaccttaaa ccttcagcgc
     5941 gcggtgagtt ggaaattacc gatattaacc gtatctacct ggagcagggg cgtctgtccg
     6001 ttgcgatgat ggggcgtggc tatgcatggc tggatacggg tactcatcag agccttattg
     6061 aggcaagtaa ttttattgcg acgattgaag agcgtcaggg gcttaaggtt tcttgcccgg
     6121 aagagattgc gtatcgcaaa gggtttattg atgcggagca ggtgaagaag ctggctgagc
     6181 cgctgaagaa aaatgcctat ggtcaatacc tgcttaagat gattaaaggt tactaagaca
     6241 tgaatgttat taaaacagat atcccagatg tacttatttt tgagccaaaa gtttttggtg
     6301 acgatcgtgg ttttttcttt gagagtttca gccagaaagt attcgaagag gcagtagggc
     6361 gaaaagttga gtttgtacag gataatcatt ctaaatcctg caagggtgtg cttcgcggtt
     6421 tacattatca actggaaccg tatgcgcagg gaaaactggt gcgctgtgtt gctggtgaag
     6481 tatttgatgt tgcggtcgat attcgtaaat cctctccgac ttttggaaaa tgggttggcg
     6541 tgaatctttc cgctgagaat aaacgtcagt tgtggatccc agaagggttt gctcatgggt
     6601 ttcttgtgct gagtaatatt gctgaatttg tatataaaac tacaaattac taccaccctg
     6661 aaagcgatag ggggcttatc tggaatgatc gtgatatagg tattgtatgg ggtgatacag
     6721 ataatgtcct actttcagaa aaagaccaaa aacagccttc tcttactgaa cttttaaacc
     6781 aacaatagga tgtgctgcac tatgaaacga attattactt ttggcacatt tgatgtattt
     6841 catgtaggcc acatcaatat tattgagaga gcgaaaaagc taggtgatta cttaattgta
     6901 ggggtctctt cagacgagct taattttagc aaaaaacagc gatatccaat atataaccaa
     6961 actgatcgtt taaaaataat tagttcaatg aaatgtgttg atgaggtttt cattgaggaa
     7021 tctttggagt tgaaattaga gtacataaaa aaatacaaag ctgacatttt ggttatggga
     7081 gatgattgga ctggaaggtt tgattgggta aaaacagatt gcgaagtgat ttatttacca
     7141 agaacacctt cggtttcaac cacagaaatt atagaaatcg ttaaatccat ttagtggaag
     7201 acaattgtgc caaaaaaaaa tgttgtagaa aatattattt ttttatcaat aattcaattc
     7261 gccaattatc ttgcaccttt gatggtctta cctttcctca gtcgcacttt gggcgtggag
     7321 gggtttgggc tcattatggt agcattttct gcatgtacat tatgttttct cctcactgat
     7381 tttggcttta atttatctgc tccatattgg atagctagga attcaaatta taggaataga
     7441 gtgtcgcgaa caataggcgc tatattttta attaaattta taatattact aattatagga
     7501 ttaatacttt tcttgtatgt attattctta acgagtaaca cgatgcatat gagattaatg
     7561 tatacaataa tttattgtat agctattgca caagcattcc aaccagtatg gttttttcag
     7621 ggggttgaga aaatgaaaaa tgtgaccata tttatggtca ctgcaaagtt atcttattta
     7681 atacttatat ttctctttgt gagaaataaa gaagatgacc ttctggttct gttatgcttc
     7741 tttataagta attttattgc aacgattatt ggtgtcgggc ttatctgggg ggcaggttat
     7801 aaaatcatga ttccgacaaa aaaaatcatt gccgatactt tcaaagcaag ttcctccttc
     7861 ttcctttcaa gattggcagt cggtgtttat acaaatgcta gcacactgat tgttggtgca
     7921 gcttcgggtg tggttcaagc gggtttgtat tcaagtgcgg aaaaattata tcaagcaggt
     7981 caaaatttaa catctccaat aagccaagca ttgtatccat atgttgcaag aacaggaaat
     8041 aaaaatattc ttttcaaaac gatcttacta cttttgattc caatgatatt gggctgctca
     8101 atctgtttta tttacgcagc cgaaataatc aaattaatat atggtgccag ttttgttaat
     8161 gcacaacatg tattaagaat atttttgata atatcaataa ttacttttgt tagtataaat
     8221 ttgggttatc ctgcctttgc ggcaatgggg agagttaatc tggctaatta tacagtaatg
     8281 cttggtggga tcgtgcaagt tttactgtta gcgatacttt atactataaa tagtattaat
     8341 gctgtgaatg ttgctttgtc tgtacttacg acagaaatta tagttttagc cgtaagaata
     8401 ttattactta taaaaccaaa tattaatact catgaagaat atcgttaaaa taccggttaa
     8461 atttgtggct gtatgcgctc ggatgctatc aataactttg gcatgtctta taccaaaaga
     8521 aaaaaaactc tgggtttttg gtggatggta tggacaacga atttctgaca acccaaaata
     8581 cttactccaa tacgtaaata aatatcacgc gaaaaatatt cgagctgttt ggatttataa
     8641 aaatgctaat gttaaagcag aggcattgaa gcttggtatc gaagcgtatc attataagag
     8701 tattaaagga aaactcatac aacttcgtgc tggtctggtt ttatttacac atacaataca
     8761 cacagattta aattcaaagt gtatctcctg gaatacaaaa cgtatacaaa tgtggcacgg
     8821 tatacctctt aaaaaaatag gatttgatga taacttcaca gcttcaaaac ttaagaaaag
     8881 taagctgtat agatttacac tcaacgacat taattcttat gtgttaagtt caggaaacgc
     8941 cgtatcgaaa atctttcaat ctgcttttga tgaatcactt ggaaaaatgg ctgaaactgg
     9001 ctttccgaga aatgatgttt ttttcaataa gcaacaccag aaaataagtg gtaaatataa
     9061 tgtcttgtat atgccaacct taagggctgg ttatggagca acgtttaatt tattggataa
     9121 aagatatgat ttccagttcg aagaaataga ttctttttta aaggagcatg atataacact
     9181 gacattgaga attcaccctg caaataatcc tgatgctaaa atggttgaac tgatagcagc
     9241 aagtgacagt ataaaaatgt catcgtcgga tgatgtttat gatgaaattg ggatgtatga
     9301 ttgtttgatt accgattatt caagtataat gtttgatttt gcactgagtc ataaaccaat
     9361 tatctttgct gcttttgata ttaaagatta tctcagagac gacagaggta tgtattttaa
     9421 ttacgaagat attgctagta ataacatcgc ctttagttgg caagatgtta tgttttcatt
     9481 aaaagaaaat ataaatgtac gagaacatca agattataaa tttcttttac aattccatga
     9541 cgatcaaaat ttactcggta aagaacatta ttactcacgt aaggtttatg aattcttaat
     9601 tgaaaagtta aatattcatg tttcttagtc caaatgagct acttcacgag tctctattaa
     9661 aatggcattc attagattcg ttaattttct gattatcttt ttcatttcta tcgatatggg
     9721 gggcgaatta ggtattagga atgtttcatt tctcttgttg gtattattaa ttgcctatta
     9781 tatcgtcact tgcaaaaaaa tcaaatttag gctgccttac gtactcctta ttatattgtt
     9841 tttaggatac cctgttgcat ctttatttat tgggatgtct aataattttg atgcagatac
     9901 tggcatatca caaatcagta tatttgtttt tgcattttta tactttctaa aaaggataat
     9961 cgaagaggat aataatttac ctctgatgcc gatacaatat tttaataatg cgatgctgat
    10021 tatctctttg ttctatgtct taatgcttat ttcgtatcaa tttttccctt ctattttcaa
    10081 tagtattgct ctttacatac acgatagagg tgctggtttt gctggcgtaa gaactgaaaa
    10141 tggagttggt tttgctaata tttatcttaa atctagcctt tttttaatat ttacttattg
    10201 ctgttttttg aagagaaata ccattaaggc tgctattata atattggcta ctgtgattac
    10261 gacatctaaa gcgcttctat taacagaagt attacttctt gtaaccaaat taaagggtag
    10321 attgatttct gttgttgttt ttgtttcggc tttgttgtta tttattgcaa tttatttcga
    10381 tgaaatcatg gttgtattca actacatgaa tgaaacattg caaggcaata gcgaaacata
    10441 tttggttaga gtgcatcact ttgaagatct agttgcgctt ttctcggaaa atccaattaa
    10501 ttttcttttt ggttttggtg caggaagttc atttttctca tcgtattatg ggaagtacat
    10561 atttaatata gaattagacc atctaaacgc gattagaaag tttggcctca tctggttttt
    10621 atcttttatg tggcttgtat tctttaatat tatccaactt gttagattaa aaagaaatga
    10681 attggctctt gggctttttc tttctttcgt cctggcaggt accaacccag tattactgag
    10741 ccctatattc tttatattat taatcgaatg tcatttattg acacttaaag taccatgttc
    10801 aactagtggg ctacacaata gtaaggtgta attcttttta tgtttaataa atctaaaaag
    10861 ttagctattt tactttccag ttataatggc gagcaattta tagaacaaca actacaatct
    10921 cttatcgaca tgaaggctga tttcattttc gatattcata ttagagatga tggttcaagt
    10981 gataaaactt gtgaaactat taagaagttt tcccagaaac atgctaacat tcatttatac
    11041 gaagagaata atgttggagt tattgcaagt tttctttggc ttgtagaaaa agtatcaggc
    11101 tatgattatt atgctttttg cgatcaagat gatttttggc aaccattgaa agccttggca
    11161 gcaattgata aatttgaaaa acacgaggaa ataactccgc tggtgtattg ctcagcttat
    11221 gattacgtcg atcaaaatct taactttatt ggtcgcttta cttccaaaag taatttttcc
    11281 cctagtaatc tgttaataga aaattgtgct cctggttgta cgatgttatt caattcagcg
    11341 ctgcgagaaa aatatttaag cataagtgct gcaaatataa gtaatcgagt tgtgatgcat
    11401 gattggcttt ttttattatt gggccttcat ttcggaatgg taatttatga cagaaattcc
    11461 tatttattat ataggcaaca tgcaaacaat gttataggta aaaaatctgg gttgctgcct
    11521 atctttagat ccaagtataa gcaattcatc aaagaatgta aaagaccgca gcatttactt
    11581 tatcttcaaa acgaattgtt ctctgatatc acctctggac aagtaaattc cttaacgcat
    11641 aaactaagtt gtagtttcgt ttccgctcaa agaaattttt actctagagc taaatttgcc
    11701 tttagcggga aaataaagcg tatccgaaaa gttgatgatt taatatttaa gattttattt
    11761 gtttttggat attataaata atatggtttg gaatcaatga gtcaacttaa aaaattacat
    11821 attgtccttg taggtaatac attatggtca gtttataatt tccgtagagg tctaattcaa
    11881 agctttatga gcaatggtca tagagtgaca atagttggac ctaaggatga gtttactgag
    11941 aaattagagg gattaggctg tgatgttgtt gatattccta tttcatcgca aggtaaaaat
    12001 ccttttattg acatgctact tataaatcga ctgagagttg tttataaaag gattaaaccg
    12061 gattttgttt ttcactatac tataaagcca aatatatatg gctcgattgc tgctggcttg
    12121 tctcgaacaa aatcaatagc tattactacc gggcttggtt atgttttcaa taactcttca
    12181 tttttcactc acataatttc acatttgtac tgctttgcat ttaaattcgc aaaagaagtc
    12241 tggtttttga atgaagatga tagaaatgtg tttatacaaa gaggtattat ctcacctggc
    12301 aagactcata ttcttgatgg cgaaggtgtc gatactagtt tcttcattcc tagggcaaaa
    12361 cctatttcgc ataaaaaatc aaaagttacg tttttgctcg ttgcaaggat gctgtgggac
    12421 aaaggtgttg ggatatacgt tgatgcggct cgtaaactaa aagaacagta cccagatact
    12481 gaatttcagt tgttaggggc ctgcgatgtc gataatccga gcgcaattcc acgtgatatt
    12541 atagataatt ggcatgaaga gggtgtagtt aattatttgg gaatgacgaa tgatgtgcgc
    12601 accgttgtat cccaagccga ctgtattgta ttgccttctt attatcgcga gggagttcct
    12661 cgaacattga tggaagcagc atcaatgggc aaaccagtac ttacgaccga taatgtcgga
    12721 tgtagaaatg ttgttataga agcgcaaaca ggttttttat gcaagacaaa agatgtcgat
    12781 agtttagttg acgctatgaa taagattctc catttaaccc ctgaggaacg tagcgaaatg
    12841 ggtctaaatg gtcgggatta tatgataagc cgcttcgatg aaagggttat tattgctgat
    12901 tattataatg ctattcaaaa atatgttgaa gtatagttgc ccctaaggat ttgtttatct
    12961 actgaccatc cgtatttgta taaagcatct tccgctatcc atgatgactt aacctgagtt
    13021 aacatcaggt atacattcaa gccgcgcaca gttacggcga acacacctga caggagtatg
    13081 taatgtccaa gcaacagatc ggcgttgtcg gtatggcagt gatggggcgc aacctggcgc
    13141 tcaacatcga aagccgcggt tataccgtct ccgttttcaa ccgctcccgt gataagaccg
    13201 aagaagtcat cgctgagaat ccgggtaaga aactggttcc tttctatacg gttaaagagt
    13261 ttgttgaatc tctggaaacg cctcgtcgta tcctgttaat ggtgaaagcg ggcgcaggta
    13321 ccgatgcagc catcgattcc ctgaaacctt atctggaaaa aggagacatc atcattgatg
    13381 gtggcaacac cttcttccag gacaccattc gtcgtaaccg tgaactctct gctgaaggtt
    13441 tcaacttcat cggtaccggt gtctccggtg gtgaagaggg cgccctgaaa ggcccatcta
    13501 tcatgcctgg tggccagaaa gaagcgtatg aactggttgc gccaatcctg accaaaatcg
    13561 ctgcggttgc ggaagatggt gagccgtgtg tgacctatat cggtccggac ggtgcaggcc
    13621 actatgttaa gatggttcac aacggcatcg aatacggcga tatgcagctg attgctgaag
    13681 cttactctct gctgaagggc ggcctgaacc tttccaacga agaactcgca gagaccttca
    13741 ccgagtggaa caaaggcgag ctgaacagct atctgatcga catcaccaaa gatatcttca
    13801 cgaagaaaga tgaagagggt aaatacctgg tcgatgtgat ccttgacgaa gcagcgaaca
    13861 aaggtaccgg caaatggacc agccagagct ctctggacct gggcgaaccg ctgtctctga
    13921 tcaccgaatc cgtattcgct cgctacatct cttctctgaa agatcagcgc gttgcggctt
    13981 ccaaagtgct gtctggtccg caggctaaac cagctggtga caaagcggaa ttcgttgaga
    14041 aggttcgtcg tgctttgtac ctgggcaaaa tcgtctctta cgcacaaggt ttctctcagt
    14101 tgcgcgcggc ttctgacgaa aacaactggg atctgaacta cggtgaaatc gcgaagatct
    14161 tccgtgcagg ttgcatcatc cgcgcccagt tcctgcagaa aatcaccgat gcctatgctg
    14221 aaaatgcagg tatcgcgaac ttgcttctgg caccttactt taagaagatt gctgacgaat
    14281 accagcaggc gctgcgtgat gttgtagcat acgctgtaca gaatggtatt cctgtgccga
    14341 ccttctccgc tgcagtagcg tactacgaca gctatcgcgc tgccgtactg cctgccaacc
    14401 tgattcaggc gcagcgtgac tacttcggtg cgcatacgta taaacgtaca gataaagaag
    14461 gtgtgttcca taccgaatgg atggaatgaa gtaacgcttt gtaatcacaa cccggagctt
    14521 gtctccgggt tttttttacg cgaaatctgg ctcctgatat tcgaagtagt ctgaatgtca
    14581 tcctgagtac agggattact cctggtttgc cttgacagtt ccgttggcca ggaggtacaa
    14641 agcccaacag tcatgtttat cgcgatggtc tggcggccat cactacagtt aactcacaga
    14701 agtcattagc gaatgaaaat aacaatctcc ggaacaggct atgttggact ctcgaacggt
    14761 attctgattg cccagaacca tgaagtggtt gcgctggata tcgtgcagtc caaagtggat
    14821 atgctcaacc agaagaaatc gccaattgtt gacaaagaaa tccaggatta tcttactcac
    14881 aaagaactga atttccgcgc tactacggat aaagaagatg cctaccgcga tgcggattac
    14941 gtcatcattg ccactcctac cgactacgat ccgaaaacga attacttcaa cacatccact
    15001 gtagaagcgg tcattaaaga cgttatcgca atcaacccga acgcggtgat ggtgattaag
    15061 tcaaccattc cggtaggttt cactaaatcc atcaaagaag agttgggcat cgataacgtc
    15121 ttcttctcgc cagagttcct gcgcgagggc agggcgttat acgataacct gcatccttcc
    15181 cgtatcgtga ttggtgagcg ttctgaacgt gctgagagct ttgctgccct actgcaggaa
    15241 ggagcaatta agaaagatat tccggtactg tttaccgact ccactgaagc ggaggcgatt
    15301 aagcttttcg ctaataccta cctggcaatg cgtgtcgctt acttcaacga actggacagc
    15361 tatgcagaga gcctggggtt aaatacccgc cagattatcg aaggtgtttg tctcgatccg
    15421 cgcattggta accactataa aaacccgtcg tttggctacg gtggttactg cctgccaaaa
    15481 gataccaagc agctgctggc aaactatcag gcggtgccaa acaacctgat ttccgcgatt
    15541 gtcgatgcca accgcacgcg taaagacttc atctctgatt cgatccttgc gcgtcagccg
    15601 aaagtggtgg gcgtctatcg tctgatcatg aagagcggtt ccgataactt ccgcgcctcg
    15661 tccattcagg ggatcatgaa gcgtattaaa gcgaagggtg ttcaggtcat tatttatgaa
    15721 cctgcaatgc aggaagatga gttcttccat tcacgcgtga ttcgcgatct ggatgcgttc
    15781 aagcaggaag cggacgtgat tatctctaac cgcatggcgg aagagctggc ggatgtggcg
    15841 gataaagtct atacccgcga tctgttcggt agcgattgat tattttaacg cgcgtaaaaa
    15901 acccggccat gttgccgggt ttttttattt tcagaccttg tagaaagcgc gataccactc
    15961 cacgaagttt ttcaccccgt ctttaactga ggtctgcggt ttaaagccaa taacgtcata
    16021 caacgctttc gtgtccgcgc tggtttccag cacgtcaccc ggttgaatcg gcatcatgtt
    16081 tttctctgct tctttgccga gtgcttcttc cagcgccgta atgtaatcca tgagctcaac
    16141 cggagagctg ttaccaatgt tgtaaacccg ataaggcgcg gaactggtcg ccggcgaacc
    16201 ggtttcgaca gtccagtttt catcagcctg agggatgaca tcctgtaggc gcagaatagc
    16261 ttcggcgatg tcatcaatat aggtaaagtc gcgcttcatc tttccgtagt tgtaaacatc
    16321 aatgcttttg ccttcgatca ttgcctttgt aaacttaaac agcgccatgt ccggacgtcc
    16381 ccacgggcca tacacggtaa agaaacgcag accagtggtc ggcaggttat acagatggga
    16441 ataagtatac gacatcagct cattggcttt tttggtcgcc gcgtacagtg acaccgggtg
    16501 gtctaccgag tcgtcagtag agaagggcat cttacggttg aggccataaa ctgaacttga
    16561 tgacgcatac agcaggtgct gtaccttgtt atggcaacaa ccttccagca cgttaaggtg
    16621 accgtccagg ttagcatccg catacgcgtg cggattttcc agcgagtagc gcacacctgc
    16681 ttgtgcggcc agatgtatca cgcgctcaaa cttctcagag gcaaacagcg ctgccatggc
    16741 ttcacgatcg gctaactcca tcttgtggaa ggtgaaagtc ccggatttca gtaaatccag
    16801 acgtgccagc ttgagattga cgtcgtagta gtcgttcaga ttatcaatac cgactacctg
    16861 gtgtccggca tccagcaagc gtttgctgac atgcgatccg ataaatcctg ccgcgcccgt
    16921 aaccaaaaat ttcatatctt cctcgttaac tcttcgttct tgtcgatgcc tgagactgag
    16981 gtgtactggc aatagcggac actaccattt gttctttttt taagcagcca tctgatgata
    17041 tttttccctg aaggctgccg gggagatatt ccccagacga gagtgacgac gctgacgatt
    17101 gtagaaaatc tcaatgtatt cccgtattac tgagatggct tcatcccggt tattaaaacg
    17161 atagtggctc aggctctcat ttttcagcgt tccccagaag ctttccatcg gagcgttgtc
    17221 gtaacagtta cctttacgcg acattgatgt tttcagacca aactgctcct gtatgacccg
    17281 gtaatcgtat gcgcagtatt gtgaacctcg atcagagtgg tggattagcc cggcaggtgg
    17341 gcgctggctc ctgagcgcca taaacagggc tttacctgtc agctcttttg tcatgcgctc
    17401 tcccatggcg tagccgacaa tttcgcacgt ataaacatct ttgatgccag cgaggtacaa
    17461 ccatccctcc tgtgtggcaa catacgtcag gtccgccacc cagacctgat ttggtgctgt
    17521 aggagcgaac gtctggttca gcagatttgg cgcaactggc agattgtggt tcgagttcgt
    17581 agtcgctctg aacttgcgtt tctgcttaca gcgtagcctt agctccttac gaagacgtgc
    17641 cagtcggtca cgaccaacga tgatgccatt ctctgccagc tccgtctgga gccgccgggt
    17701 tccatatgtt tcgcgagtgc ggatatgtgc caccttaatc tccagtttta gccgctcatc
    17761 actttgtttt ctgtctgagg gttcatgctg tacccagttg taataaccgc tcctggatac
    17821 accaaatacc tgacacatcg cttcaatggg aaattgttgt cgccattgtt cgattaacgc
    17881 gtatttttca gcgactcctg tgcaaaatac gctgttgtag attcaatctg tcaatgcaac
    17941 acccctttca attatctctt tcggtgtttt gaacttcagt gtctttctcg gtctgttgtt
    18001 tagctgagca gcaaccagat ctagttcatg ttgagtatat tgggcaagac atgtcttttt
    18061 aggaaagtac tgccgaatta gcccatttgt gttctcattt gttccccgct gccaaggact
    18121 ctgaggatcg cagaagtaaa ctttaacgcc ggtgctgaca gtaaattcta gatgtctggc
    18181 cagttccatt cctctgtccc atgtcagtga ttttctgagt tctgacggta aactcaggaa
    18241 tttgtcggta agagcctgat ttactgagac agaatctttg cccctgagtc taaggatgat
    18301 cgtataacgt gattttcggt ctacaagtgt ggctatatga gagttttttg tacctgagac
    18361 taaatcgccc tcccaatgcc ccagagagcg tctgttatcg acatttcggg aacgttcgtg
    18421 aattggtgtt ccgttcacta tgttaatcgt acctctttcg cctttgcggg tatgacgcct
    18481 gccatggcga aggctatgcg accgtcgcag atgctgtata ttcaggtggt gtagcgcttc
    18541 acggctacga aagtacagcg ttttataaat tgtctcaggt gatattcgca gcgttttttg
    18601 acgtggtttt gttcgcctta accatcctga tatttgctct ggagaccatt tcatctccag
    18661 cttttccaga acaagctttc gcaatggcaa attttgatcc agtaagcacg gttttggcct
    18721 tttcgccatt ctgttggctc ggttattagc atcaacagct ttgtaatagc gtctgccccg
    18781 attacgctga acttcacgtg agatcgtcga aggactgcga ttcagcgcag tagctatcgc
    18841 acgaatgctc attttggctg acaaaccagc tcgtatctcc tcgcgctcag acagtgtcag
    18901 gtgagctaca gcccgcttac gctcatgggg ttttatgccg ccagtatccc ttaacatagt
    18961 gaagatcgtt ccgggttttg aacccaggat attcgctatt tcactgaagc ctgttccgtt
    19021 cttccatagt tcaaaaacag aggctttttc ctctgctgta aatgttcgtc tcattcaaaa
    19081 aacctccgca accccatgtt ttcacataac tgttgcgttg accaattgaa tctacagttg
    19141 ctttttttaa tatatctcgc tcaaggcgag cttcatttaa cgccttacgc agttgcagaa
    19201 tttcagattc cagttcagcc accgtgcggg aaccaggagt accgagccct tttctggcag
    19261 cggtaaccca ttgtcctaaa gtgccttcag gaagagataa tcgggaagcg ccttcactga
    19321 tcgaaagttg attttcaaga accgttctga cagcttcggc tttgaactct ttagagtaac
    19381 gttgggtttt tctgctcatt attagctcct tctgatgcca ttctatttca ggaaggagtg
    19441 tccgttaaac tcaggctacc tcagacatca gaattactat atgatagcgc gttggccgcg
    19501 agttatataa cccatctttc cgatataact catcggattc tgatagaaaa atcgctggca
    19561 acagatacac aatgtagaca tcactttttt gccctttttc atctgttagg gattgtatga
    19621 cgcagaacaa caatactccg gttaatagca gtaatggtcc ggagcaaatt gatttacttg
    19681 atttagtgct acagctgtgg cgtggaaagt gggtaattgg cgcttttgtt gctgttttta
    19741 tcatcattgc gggtatttac atcatcgttg caaaagaaaa atggacctcg tccgccatta
    19801 tttcccagcc ggatgcggcg cagattacca catacgcgaa tgcactgaat atcctttatg
    19861 gtagtgccgc tccttcaatg caggatatcc aaaaccgtgc cattggtcgt ttcaattcct
    19921 cattttctgc tttagcctgg gcgcttgaaa accaggaaat gccagaaaaa ctgaccattg
    19981 ataccaccgt taaaggtcaa gcgttgccgt tgagcgtcac ctatcaaggt gaatctgctg
    20041 aagcggcaca aaagcagctg gcgcaataca ttcagcaggt agacgaacaa acggcgaagg
    20101 aacttgcgct cgaccttaaa gataacatta agcagcagat caccagcctc aatgactccc
    20161 ttgaaaacca ggagaaagtt gctcaggagc agaaagatct gcgcattaaa cagatttctg
    20221 aggcgcttaa gaacgcggaa gcggcgaaaa ttaccactcc gcagatccag caaactcagg
    20281 acgtgactca ggaaaccatg ttcctgctgg gaagcgaagc gctgaaatcg atgattgata
    20341 acgaagcgtc tcgtccgctg gtcttctccg gtacgtatta tcagaccaaa caaaacttgc
    20401 tggatattga gaagctaaac gtgaagccgg acaccattca tgtctatcgt tacgtcatga
    20461 agccggatct tcctatccga cgtgacagcc cgaaaaaggc catcgcgttg attctggcag
    20521 tcttgctcgg tgcgattatc ggttctggtg tggttctcgg ccgcaacgcg ttgcgtaact
    20581 acaaaccaaa agtctgactt gcagataaaa aaaccgggga aattccccgg tttttttatt
    20641 tatgccgctt acgaagattc tcaatcaccg ccgttaaatc cagctcctga tcctgcagaa
    20701 gtaccagcag gtgatacatc aaatcagacg cttcgttggt cagctcttcg cggtcatgca
    20761 ccgtcgcggc cagcgcggtc tcaacgcctt cttcacccac tttctgcg
//
