LOCUS       AE015928               15101 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Bacteroides thetaiotaomicron VPI-5482, complete genome.
ACCESSION   AE015928
VERSION     AE015928.1
DBLINK      BioProject: PRJNA399
            BioSample: SAMN02604314
KEYWORDS    .
SOURCE      Bacteroides thetaiotaomicron VPI-5482
  ORGANISM  Bacteroides thetaiotaomicron VPI-5482
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 15101)
  AUTHORS   Xu,J., Bjursell,M.K., Himrod,J., Deng,S., Carmichael,L.K.,
            Chiang,H.C., Hooper,L.V. and Gordon,J.I.
  TITLE     A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis
  JOURNAL   Science 299 (5615), 2074-2076 (2003)
   PUBMED   12663928
REFERENCE   2  (bases 1 to 15101)
  AUTHORS   Mahowald,M.A., Rey,F.E., Seedorf,H., Turnbaugh,P.J., Fulton,R.S.,
            Wollam,A., Shah,N., Wang,C., Magrini,V., Wilson,R.K., Cantarel,B.L.,
            Coutinho,P.M., Henrissat,B., Crock,L.W., Russell,A.,
            Verberkmoes,N.C., Hettich,R.L. and Gordon,J.I.
  TITLE     Characterizing a model human gut microbiota composed of members of
            its two dominant bacterial phyla
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 106 (14), 5859-5864 (2009)
   PUBMED   19321416
REFERENCE   3  (bases 1 to 15101)
  AUTHORS   Xu,J., Bjursell,M.K., Himrod,J., Deng,S., Carmichael,L.K.,
            Chiang,H.C., Hooper,L.V. and Gordon,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2002) Department of Molecular Biology and
            Pharmacology, Washington University in St. Louis, 660 S. Euclid, St.
            Louis, MO 63110, USA
REFERENCE   4  (bases 1 to 15101)
  AUTHORS   Mahowald,M.A. and Gordon,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2009) Center for Genome Science, Washington
            University in St. Louis, 4444 Forest Park Ave., St. Louis, MO 63108,
            USA
  REMARK    Protein update by submitter
COMMENT     On or before Jan 5, 2006 this sequence version replaced AE016926.1,
            AE016927.1, AE016928.1, AE016929.1, AE016930.1, AE016931.1,
            AE016932.1, AE016933.1, AE016934.1, AE016935.1, AE016936.1,
            AE016937.1, AE016938.1, AE016939.1, AE016940.1, AE016941.1,
            AE016942.1, AE016943.1, AE016944.1, AE016945.1, AE016946.1.
FEATURES             Location/Qualifiers
     source          1..15101
                     /organism="Bacteroides thetaiotaomicron VPI-5482"
                     /mol_type="genomic DNA"
                     /strain="VPI-5482"
                     /type_material="type strain of Bacteroides
                     thetaiotaomicron"
                     /db_xref="taxon:226186"
     gene            complement(1..2271)
                     /locus_tag="BT_1032"
                     /old_locus_tag="BT1032"
     CDS             complement(1..2271)
                     /locus_tag="BT_1032"
                     /old_locus_tag="BT1032"
                     /note="alpha-1,2-mannosidase-like"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92"
                     /protein_id="AAO76139.1"
                     /translation="MRRILLTCTLAFTLLPVFGGEGKAPPMDKEKSLLIDYVDPFIGTT
                     NFGTTNPGAVCPNGMMSVVPFNVMGSADNTYDKDARWWSTPYEHTNCFFTGYSHVNLSG
                     VGCPELGSLLLMPTTGELNVDYKEYGSKYKDEQASPGYYSNYLTKYNIKTEVSATPRTG
                     IARFTFPKGESHILLNLGEGLTNESGAMLRRVSDSEIEGMKLLGTFCYNPQAVFPIYFV
                     MRVNKVPATTGYWKKQRPMTGVEAEWDRDQGKYKLYTRYGKEIAGDDVGAYFTFETEEG
                     EQVEVQMGVSFVSIENARLNLDKEQSGKNFEQVLSDARAQWNDDLSRITVEGGTDAQKT
                     VFYTALYHLLIHPNVLQDVNGEYPAMESDQILTTKGTRYTVFSLWDTYRNVHQLLTLVY
                     PERQMEMVRTMLDMYREHGWFPKWELYGRETLTMEGDPSIPVIVDTWMKGLRDFDVDLA
                     YEAMYKSATLPGAENLMRPDNDDYMSKGYVPLREQYDNSVSHALEYYIADFALSRFADA
                     LGKKKDAEMFYKRSLGYKHYYSKEFGTFRPILPDGTFYSPFNPRQGENFEPNPGFHEGN
                     SWNYTFYVPHDVYGLAKLMGGKKPFVNKLQMVFDEGLYDPANEPDIAYAHLFSYFKGEE
                     WRTQKETQRLLDKYFTTKPDGIPGNDDTGTMSAWAIFNMIGFYPDCPGLPEYALTTPVF
                     NKVTIRLDPKWYKENELVIESNRTGSETLYINKVLLDGKKFNKYRITHDELVHGKRLIF
                     DLK"
     gene            complement(2279..3247)
                     /locus_tag="BT_1033"
                     /old_locus_tag="BT1033"
     CDS             complement(2279..3247)
                     /locus_tag="BT_1033"
                     /old_locus_tag="BT1033"
                     /codon_start=1
                     /transl_table=11
                     /product="GH130"
                     /protein_id="AAO76140.1"
                     /translation="MNKIQIPWEERPVGCTDVMWRYSQNPVIGRYHIPSSNSIFNSAVV
                     PFKDGFAGVFRCDNKAVQMNIFTGFSKDGIHWDISHEPIQFKAGNTEMIESEYKYDPRV
                     TWIEDRYWVTWCNGYHGPTIGIAYTFDFVDFFQCENAFLPFNRNGVLFPQKIDGKYAML
                     SRPSDNGHTPFGDIYISYSPDMKYWGEHRCVMKVTPFPESAWQCTKIGAGSVPFLTDEG
                     WLLFYHGVITTCNGFRYAMGSAILDKDHPEKVLYRTREYLIGPAAPYELQGDVPNVVFP
                     CAALQDGERVAVYYGAADTVVGMAFGYIQEIIDFTKRTSII"
     gene            complement(3300..4631)
                     /locus_tag="BT_1034"
                     /old_locus_tag="BT1034"
     CDS             complement(3300..4631)
                     /locus_tag="BT_1034"
                     /old_locus_tag="BT1034"
                     /note="beta-lactamase-like induction signal transducer"
                     /codon_start=1
                     /transl_table=11
                     /product="putative signal transducer"
                     /protein_id="AAO76141.1"
                     /translation="MQQNKTASQGKTINPIYWVPTAYFAMGLPFIAINLVSVFMFKDLG
                     ISDTQITFWTSLIMMPWTLKFLWSPFLEMYRTKKFFVLVTELLSGILFGVVAFSLFFDY
                     FFAISISTMAVIAFSGATHDIACDGVYMAELNKEDQAKYIGVQGAFYNVAKLVANGGLV
                     ALAGMLAEYFGAIEGASIDANKGAYSSAWMIIFAVIAAVMVLLGLYHIKMLPSTQVPAT
                     GKKSTSEIMQDLVNVIGNFFTKKHIVYYIFFIILYRLAEGFIMKVAPLFLRASREVGGL
                     GLSLTEIGTLNGVFGSAAFVIGSLLGGIFVARYGLKKTLFMLCCVFNLPFLAYTFLAVV
                     QPTSLYLIGTCITMEYFGYGFGFVGLTLFMMQQIAPGKHQMSHYAFASGIMNLGVMLPG
                     MISGYFSDLLGYRSFFIYVLIATIPAFLMTYFIPFTYDDSKKKK"
     gene            complement(4730..6934)
                     /locus_tag="BT_1035"
                     /old_locus_tag="BT1035"
     CDS             complement(4730..6934)
                     /locus_tag="BT_1035"
                     /old_locus_tag="BT1035"
                     /codon_start=1
                     /transl_table=11
                     /product="GH163"
                     /protein_id="AAO76142.1"
                     /translation="MRIIRRIIFQLLCLLGACCYIPATAQVVLVDNGKTKSRIILSEND
                     QINQISANLFQLFLQRISGCTFPIVKGQNAKKGDIIISSKTPAGVTEDGFSLSTKDGIL
                     RISGSGNGTVYGVVTLLEQYLGVDYWGENEYSFNPAKTIELPLIDKIDNPAFRYRQTQC
                     YAIRTDSIYKWWNRLEEPNEVFAAGYWVHTFDKLLPASVYGKDHPEYYSYFKGKRHPGK
                     ASQWCLSNPEVFEIVAQRIDSIFKANPDKHIMSVSQNDGNYTNCTCDACKAIDDYEGAL
                     SGSIITFLNKLAARFPDKEFSTLAYLYTMNPPKHVKPLPNVNIMLCDIDCDREVTLTEN
                     ASGKEFVKAMEGWAAITNNIFVWDYGINFDNYLAPFPNFHILQDNIRLFKKNHATMHFS
                     QIAGSRGGDFAELRAYLVSKLMWNPEANVDSLMQHFLHGYYGEAAPYLYQYIKVMEGAL
                     IGSGQRLWIYDSPVSHKYGMLKPQLMRRYNQLFDDAEKAVAEDNKFLKRVQRARLPIQY
                     SELEIARTETGTDMNEISPKLALFEERVKEFNVPTLNERSNSPVEYCQLYRERYMPRAE
                     KSVAIGAKVTYLIPPTGKYAEIGKTALVDGLFGGSTFVESWIGWEGTDGAFVIDLGKEK
                     EIHSIDTDFLHQIGAWILFPLKVVYSYSEDGENYTHWGAHDMPENRSGKVEFRGVKTES
                     EMPVHARYVKVEVTGTKECPEWHYGVGHPSWFFIDEVTIK"
     gene            complement(7101..8450)
                     /locus_tag="BT_1036"
                     /old_locus_tag="BT1036"
     CDS             complement(7101..8450)
                     /locus_tag="BT_1036"
                     /old_locus_tag="BT1036"
                     /codon_start=1
                     /transl_table=11
                     /product="Coagulation factor 5/8 type, C-terminal"
                     /protein_id="AAO76143.1"
                     /translation="MKALFKYILYSTFFAMSLPLVTACDDDEATDPYDINYVYIYKPSE
                     TNATLEYKGDGTFLKEIATEHILSPVRCTKPAPQDLTIQLAIDRSLVDAYNSEYGTSYV
                     ALQNAELENATLYIKQGEYISVDTLKVHYTNMEEFKNGSENYILPIAITSINGTGVSAS
                     ESNSKIFLTFESTYKPNHVTLTSSKEYLLEYQYSQGFTNLSSEWKLDGILKSAWAADGD
                     TKVTLAINPALVGTYNALHGTDYSLLTSASLKQSTIMIKQGKTTPEESVALSFSDDMAS
                     VQLGTNYVIPVTITNVDGVGADIGENKVIYIVYKTALVGFLSCVDKPVGSVINDHSGWS
                     FTLNGQSSDLYDYVPDGSILDIDLGKQENIKTIALHFYEWFYSSESASIAISNDGEKYE
                     DLGVASGFANKTSYILLLVAKQAQYIRVTFHGALYYSPYINTVGIYTETE"
     gene            complement(8467..9654)
                     /locus_tag="BT_1037"
                     /old_locus_tag="BT1037"
     CDS             complement(8467..9654)
                     /locus_tag="BT_1037"
                     /old_locus_tag="BT1037"
                     /codon_start=1
                     /transl_table=11
                     /product="Concanavalin A-like lectin/glucanase"
                     /protein_id="AAO76144.1"
                     /translation="MAFGVLALVHTACENAKYDVIDNLVYINEASTSKTKELTLTEGTT
                     RTSLTVRLVNIINQTIKANLFIDESVLDAYNKKNETNYKMPPKEYISFPESVTIEAGSV
                     SADPVNVDIKSFEAEGGAQYAIPISIKNVEGGIEKSESSSSFLLVLVKPLKQAVPKLTW
                     YNGMHAAPEGAWGLALPNYTLEWWSKVTSKSGNGGYTKNNQAIINSGGLGTELYIRFGD
                     LIYSENGSYKNNFLQVKTMGSQFDTGDPTKGKGLEAQKWYHFAVSYDAASGTTLLYQNG
                     TVVASLSSSIGQPMNIDQFQMISSGEEYFPDFCEMCQVRFWKVTRTVNQIKKSMYTEVD
                     YTDKNLLLYLPMNEGEGATILHDVTGNGHDVEIGNSNLGNENRQKVTWETYSFAQ"
     gene            complement(9698..10720)
                     /locus_tag="BT_1038"
                     /old_locus_tag="BT1038"
     CDS             complement(9698..10720)
                     /locus_tag="BT_1038"
                     /old_locus_tag="BT1038"
                     /codon_start=1
                     /transl_table=11
                     /product="putative secreted endoglycosidase"
                     /protein_id="AAO76145.1"
                     /translation="MKTSKLKKIIYGIGISLFFSQGFLNIACSDWTDIEAKDYYEPPTQ
                     GYENNLKDYFNSPHKIMFGWFGNWAGKGGSSMQYALCGLPDSTDFVSLWLCWGNLTVEQ
                     QADLKDFQAKGSRAVLCWRAGDIGDNLTPGGNDDAVKEAFWGFDPKDEQSCIEAAKKYA
                     LAIVDTCNKYNIDGFDYDIEDWGTLMNSSMPSVPNAFMKTLREEFDKTGKMLVADIPGG
                     AGWLSFYEVLSEETVLSLDYIAWQTYELGHSGLDSFFEAVRRSHPNVFKEAMGKSIVTA
                     TFERAVDKHYFTEQQSYHPACGIEHAGMGAYHIEYDYPGNPDYPTVRAAIAAQNPPINN
                     "
     gene            complement(10747..12330)
                     /locus_tag="BT_1039"
                     /old_locus_tag="BT1039"
     CDS             complement(10747..12330)
                     /locus_tag="BT_1039"
                     /old_locus_tag="BT1039"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8A8X0|8.A.46.2.1"
                     /protein_id="AAO76146.1"
                     /translation="MKKNKIIKKFAKLSVYTLLVALGTGCTDKFEEYNTNPFGPKPDQM
                     LGDNAITGSLIKSMIPALVQGQQNNSQMLDQMIGSEYGGEITCIAQWGNGGNYYTYNPR
                     VGWYGNMFDTTMPQIYTGYFQIRDLSDGKGLAYQWAQILRVAASLKISDCYGPIPYSQI
                     TGTAFTVEYDNMEDLYKHMFDDLDEAISAFKVAVLGNEDMSSLSEYDLVFNGDFNKWVK
                     FANSLKLRMAMRISSVSPALAKEKAEEAVSDVIGVMTSASDAAYSKYNDGMNPYYRVTS
                     SWNEIRISANITSYLSGYNDPRLAKYASEADASIGGGQIGVRNGIYQSATTQANYTKFS
                     RLNIGIDDELLIMSASEAYFLRAEAALMYKWNMGGTPKELYDAGVTVSMEERKATIGDY
                     LKSEKVPAAYSDPSDSGKDIAAVSTVTPKYNESASVTENLERILIQKWIANFPNGWETW
                     ADIRRTGYPKLFPIVNNLNTDGVTVQRGMRRLPFPQSEYNTNNANVKAAVSMLGGADNS
                     ATDLWWAKKN"
     gene            complement(12339..15101)
                     /locus_tag="BT_1040"
                     /old_locus_tag="BT1040"
     CDS             complement(12339..15101)
                     /locus_tag="BT_1040"
                     /old_locus_tag="BT1040"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8A8X1|1.B.14.6.13"
                     /protein_id="AAO76147.1"
                     /translation="MGEDTQTLDEVVVTALGIKREQKALSYNVQQVKGDELTNIKDANF
                     INALSGKVAGVTINASSAGAGAAARVVMRGTKSLEKNDNALYVIDGIPMFNVNSGDNAG
                     GTMNKQPGSNSVADINPEDIESMTILTGPSAAALYGSDASNGVILITTKKGTVGKVQIS
                     YSNSTSFSSPMMMPKFQNIYGNREGELGSWGSLMDTPSNFDPSDFFNTGMTEMNGFTLT
                     TGTEQNQTYASVSTTNSTGILPNNAYNRYNFSIRNTAKFCDNKLSLDLGAQYIIQNNKN
                     MVGSGQYFNPLVSLYLFPRGENFQEVQMYERYSEARNLMVQYWPESIFGTDLDMQNPYW
                     IMNRMQNELSKRRYMFNASLKWDITDWVNVTGRVRVDNSDSDSYEKYYASTRGTFTESS
                     SKGYYGHTKQNDRSVYADVMASINKNFFDDKLSLNATVGASINDIQEDAMYLKGGLEQI
                     PNFFHYGNINVNTSKRNESKWHDQVQSVFASAELGWNHQLYLTVTGRNDWASQLAFTSK
                     GSYFYPSVGLSWLVSESVKLPKAISYLKVRGSWAEVASSPNRYLTQMQYTYNEQTNTYE
                     YPASHYNTNLKPENTKSWELGVNAKFLGNRINLDMTFYRSNTFNQTFYVDASASSGYKN
                     NIVQTGNIQNQGIELALGYSDTFDKVKVSTNFTYTLNQNKIVSLANGAINPETGEAIEM
                     EYYSKGTLGTSGGPTLRLYENGSMGDIYINQRLRQSPNGYIWKDPSNGSLAIENTEYRK
                     VGSILPKYYLGWNGSVAWKGWNLGFAFTGRFGGLVVSDTQAMIDKYGVSESSAVARQAG
                     GVWVGDSKVDAEEYYSKVTTAVGTYYTYSATNIRLSELSLSYQLPKTWFKNHVNMTLGL
                     TGKNLWMIYCKAPYDPESTSSVTSNFYQGVDYFQQPSLRSLGFNVKLTF"
ORIGIN
        1 ttatttcaaa tcaaatatca agcgtttacc atgaacaagt tcatcgtggg taatgcggta
       61 tttattgaac ttcttaccat ccaataacac cttatttata taaagagttt ccgatccggt
      121 acgattactc tcaattacca gctcattttc cttataccat ttaggatcca agcggatcgt
      181 tactttatta aataccggag tagtcaatgc atattccggc aatcccggac agtcgggata
      241 aaaacctatc atattgaaaa tagcccatgc agacatcgta cctgtgtcat catttccagg
      301 gataccgtcc ggtttggtcg taaagtactt atccagcagt cgctgtgtct ctttctgtgt
      361 acgccattct tcacctttaa agtaagagaa cagatgagcg taagcaatat ccggttcgtt
      421 agccggatca tatagtcctt catcaaacac catttgcagc ttattgacaa aaggtttctt
      481 tccacccatc agtttagcca atccatatac atcatgtggt acatagaaag tataattcca
      541 agaattacct tcgtggaaac cgggattcgg ttcaaagttc tctccctgcc tcggattgaa
      601 cggactgtag aaagttccgt ccggaagaat aggtcggaat gtaccgaact ccttactata
      661 ataatgctta tatcccaaag agcgtttata gaacatttcc gcatctttct tctttcctaa
      721 agcatccgca aaacgggaaa gggcaaagtc tgcgatataa tattccagtg catgagatac
      781 ggagttatca tattgttcac gaagcggcac gtatcctttt gacatatagt catcattgtc
      841 cggacgcatc agattttccg ccccgggtaa tgtagccgac ttgtacatag cttcataagc
      901 cagatctacg tcaaagtcac gcaatccttt catccatgta tccacaatca ctgggatact
      961 tggatcacct tccatcgtaa gagtctctct tccatacaat tcccatttag ggaaccaacc
     1021 atgttcacga tacatatcga gcatggtacg taccatttcc atctgacgtt cgggataaac
     1081 caaagtcaaa agctgatgta cgttacgata tgtatcccac aaagagaata cagtatatcg
     1141 ggtacctttc gttgtcagaa tctgatcgct ctccatagcc ggatattcac catttacatc
     1201 ctgcagaacg ttcggatgaa tcaacaaatg ataaagtgcc gtataaaaaa ctgttttctg
     1261 tgcatccgtt cctccttcta cagtgatacg tgacaagtca tcgttccact gtgcacgggc
     1321 atcggaaagc acctgttcaa agttttttcc cgactgttct ttatccagat tcaaacgggc
     1381 attctctatg cttacaaagg aaactcccat ctgtacttcg acctgttctc cttcttctgt
     1441 ttcaaaagtg aagtaagcgc ccacatcgtc acctgctatt tcttttccat agcgggtata
     1501 caatttatat ttgccttggt cgcgatccca ttctgcttcc acacctgtca tcggacgttg
     1561 ctttttccaa tatccggttg tggcgggaac tttgttcact ctcatcacaa aatagatggg
     1621 aaatacagct tggggattat aacagaaagt acccaatagt ttcattccct ctatttcgct
     1681 gtcacttaca cgacgaagca tggctccact ctcattggtc aggccttcgc ccaaattcag
     1741 aagtatatga ctctctcctt taggaaaagt gaaacgggca atacctgtac gcggagtagc
     1801 agagacttct gtctttatat tatacttcgt caaataattg gaataatagc cgggagaagc
     1861 ctgttcatcc ttatatttgc tcccatattc cttatagtct acattcagtt ctccggtagt
     1921 aggcatcagc aataaagaac ccagttcagg acaaccgaca ccactcagat tcacatgaga
     1981 atatcctgta aagaaacaat tggtatgttc ataaggcgtc gaccaccaac gtgcatcttt
     2041 atcgtatgta ttatcggcag aacccatcac attaaaaggt actacggaca tcattccatt
     2101 cgggcaaaca gctccgggat tggtggtgcc gaagtttgtc gttccaataa aaggatctac
     2161 atagtctatc aacagactct tttccttatc catagggggg gccttaccct ctcccccaaa
     2221 tacggggaga agggtgaaag ccagtgtgca agttaataat atacgtctca tatccttctt
     2281 agataatgct cgttcgtttt gtaaaatcaa ttatttcctg gatatagccg aaagccattc
     2341 ctacaacggt atctgcagct ccataataaa cagctacacg ctcaccatcc tgcaatgccg
     2401 cacatgggaa taccacattg ggcacatccc cttgaagttc ataaggtgca gccggaccta
     2461 tcagatattc acgggtacga taaagtacct tttcgggatg atccttatcg agtatcgccg
     2521 aacccattgc ataacggaaa ccgttgcaag tagtgataac accatgatag aaaagcaacc
     2581 agccttcatc agtaaggaaa ggtaccgaac ctgcaccaat cttggtacac tgccaggcac
     2641 tttcagggaa aggagttact ttcatgacac aacggtgttc accccagtat ttcatatccg
     2701 gactgtagct gatataaata tcaccgaacg gtgtatgtcc attgtcgctg gggcgactta
     2761 acatagcata tttgccatct atcttttgcg ggaaaagtac tccattacga ttgaaaggca
     2821 ggaaagcatt ctcgcattgg aagaaatcta caaaatcaaa tgtataggca ataccgatag
     2881 taggtccatg atagccgttg caccaagtta cccaataacg gtcttcaatc cacgtaacac
     2941 gcgggtcata tttatattcg gattcaatca tttccgtgtt accggctttg aactgaatcg
     3001 gttcatgact aatatcccaa tgaataccat ctttactgaa tcctgtgaag atgttcatct
     3061 gtacagcttt gttgtcacaa cggaatacgc cggcgaatcc atctttgaaa ggtacgacag
     3121 cactgttgaa aatactattg gatgaaggaa tatgatagcg tccgatgacc ggattttgcg
     3181 agtaacgcca cattacatct gtacatccga caggacgttc ttcccaggga atttgaatct
     3241 tattcataat aattatttat ttagtaattg gttatctatt atcactcaaa aatagcaatt
     3301 tattttttct tttttgaatc atcatacgta aaaggtataa aataggtcat caaaaaagca
     3361 ggaattgttg cgatcagtac atagataaag aaactacggt atcccagtaa atcactaaaa
     3421 tagccgctga tcattcccgg aagcataact cccagattca tgattcccga agcaaatgca
     3481 taatgtgaca tctgatgttt gccaggagca atctgctgca tcatgaacaa ggtcagtccg
     3541 acaaatccga aaccatagcc gaaatactcc attgtgatac atgttccgat cagataaaga
     3601 ctggtcggct ggactacagc aaggaaagta taagcaagga aaggaaggtt gaacacgcaa
     3661 caaagcatga ataaagtttt cttcaatcca tatctggcaa caaatattcc acccagcaat
     3721 gaaccgataa caaaggcggc agaaccaaag acgccattca atgttccgat ttctgtcaat
     3781 gacagcccca gacctccgac ctctctggag gcacgcagaa acaaaggagc aaccttcatt
     3841 ataaatcctt ccgccaatcg gtagagaata atgaagaaga tataatatac tatatgtttt
     3901 ttagtaaaaa agttcccaat cacatttacc aaatcctgca tgatttctga ggtagacttc
     3961 ttgccggtag cgggaacttg tgtagaaggc aacatcttta tatgataaag accgagcaat
     4021 accattactg cagcaattac ggcaaaaata atcatccatg cagatgaata cgcaccctta
     4081 ttggcatcta tcgaagctcc ttctatcgct ccgaaatatt cggccagcat acctgccaaa
     4141 gcaactaatc caccgttggc aaccaatttt gccacattat agaaagctcc ctgtactcca
     4201 atatatttag cctgatcctc tttattcagt tctgccatat atacaccatc gcaagcgata
     4261 tcatgtgtgg ctccactgaa cgcaatcacc gccatagtgg aaatactgat agcaaagaaa
     4321 taatcaaaga ataacgaaaa agctactact ccaaacaata taccactcaa cagttcggtt
     4381 accagtacaa aaaacttttt ggtccgatac atttcaagaa aagggctcca taagaatttg
     4441 agtgtccagg gcatcatgat aagagaagtc caaaacgtta tctgagtatc agaaataccc
     4501 aaatccttaa acatgaatac ggaaaccaaa ttgatggcaa taaagggaag tcccattgca
     4561 aaataagcgg taggtaccca ataaatcggg ttgatagttt ttccttgaga agcagtttta
     4621 ttctgttgca tagttcaata gtatatagat gaaagggtca tttttctgac ccatctatat
     4681 ataatacaac taagaagggc aaactactaa cgcttgcccc tacttttttt tattttattg
     4741 ttacttcgtc gataaagaac cacgaaggat gccctacacc ataatgccat tcgggacatt
     4801 ctttcgtacc ggtgacctca actttcacat aacgggcatg cactggcatt tccgattcag
     4861 tcttcactcc gcggaactcc actttccccg aacggttttc cggcatatca tgtgctcccc
     4921 aatgtgtata attctctcca tcttcagaat aggaataaac caccttcaga gggaaaagaa
     4981 tccaggctcc gatctgatgc aggaaatccg tatctatact atgtatttct ttctctttac
     5041 ccaaatctat aacaaaagca ccgtctgttc cttcccagcc aatccagctt tcaacgaaag
     5101 tagatcctcc gaatagtccg tccactaatg ccgtttttcc gatttctgca tatttaccgg
     5161 taggaggaat aagataagta accttcgctc ctatcgcaac acttttttct gcacggggca
     5221 tatatctctc ccgatacaac tggcaatatt ccacaggaga attggaacgt tcattcaatg
     5281 tcggtacatt aaattctttc acccgttctt caaaaagtgc caatttcgga ctgatctcat
     5341 tcatatccgt accagtctca gtacgggcaa tttccaattc cgaatactga atgggcaagc
     5401 gggcacgctg cacacgcttc aggaatttat tatcttcagc caccgctttc tctgcatcat
     5461 caaacagttg attataacgt cgcatcagtt gtggtttcag cattccgtat ttatgggaaa
     5521 caggagaatc ataaatccac aatctttgtc cgctgcctat caacgctccc tccatcacct
     5581 tgatatactg ataaaggtat ggcgcagcct ctccatagta tccatgcagg aaatgctgca
     5641 tcaaagaatc aacattcgct tcggggttcc acattaactt agataccaga taggcacgta
     5701 actcagcgaa gtctcctccc ctgcttcctg caatctgtga gaaatgcata gtggcatgat
     5761 tctttttgaa cagacggata ttatcctgca agatatgaaa attagggaac ggagccagat
     5821 aattatcaaa attaatacca taatcccaca cgaaaatatt attagtgatg gcagcccagc
     5881 cttccattgc tttcacaaac tctttacctg aggcattttc cgtcaaagtc acttcacggt
     5941 cacaatctat atcacaaagc atgatattca cattcggcaa tggcttcaca tgtttcggag
     6001 gattcatcgt atacagatag gcaagcgtgg aaaattcctt atcgggaaaa cgggcagcca
     6061 gcttattcaa aaaagtaatg atacttcctg agagtgctcc ttcataatca tctatcgctt
     6121 tgcaggcatc acatgtacaa ttggtataat taccatcatt ctgactcaca gacataatat
     6181 gcttatccgg atttgcctta aaaatagaat caatccgctg agccacgatt tcaaaaactt
     6241 ccgggttact cagacaccat tggcttgctt tcccgggatg gcgtttgcct ttaaaataag
     6301 aataatattc cggatggtct tttccatata cggaagcagg aagcaactta tcaaaagtat
     6361 gcacccaata accggcagca aacacttcgt ttggctcttc cagcctgttc caccatttat
     6421 atatggagtc tgtacgaata gcataacatt gtgtctggcg gtaacggaaa gccggattat
     6481 ctattttatc gataagcggc agttcgattg tcttcgcagg gttaaaagag tattcgtttt
     6541 ctccccagta atccactcca agatattgtt cgagtaaagt tacaactccg tagactgtcc
     6601 cattcccact gcctgaaata cgtaagattc catctttcgt agataggctg aaaccgtctt
     6661 ctgtcactcc agctggggtt ttgctactga ttataatatc tccttttttt gcattctgcc
     6721 cttttacaat gggaaatgta caacctgaaa ttctctgaag gaacaattga aataaatttg
     6781 ctgatatttg attaatctgg tcattttctg atagaataat cctggattta gtttttccat
     6841 tatcaactaa aacgacttgt gctgttgcag gaatataaca acatgctccc aacaaacaaa
     6901 gcagctgaaa aataatacgg cgaatgattc tcatagcatt tcctttaatt agtttttaga
     6961 taatacaatc caaaaatata agatactcaa gaaaaaaatc agttctaagt tttattaaca
     7021 aagaaaactt agaactgatc acaacatgat ataaacagca aatagcccaa gctcattcag
     7081 taataaactt gggccatttt ttattcagtt tcagtataaa tacctacagt attaatataa
     7141 ggagaataat aaagagctcc atggaaagtt actcttatat attgcgcttg tttagccaca
     7201 agaagaagaa tgtaacttgt cttatttgca aatcctgaag ctacaccaag atcctcatat
     7261 ttctctccat cattacttat cgctatactt gcactttccg aagaataaaa ccattcatag
     7321 aaatgtaaag caatagtttt tatattctct tgttttccca aatcgatatc aagtatgctg
     7381 ccatccggaa cataatcata caagtcgcta gattgtccat tcaaagtaaa actccaaccc
     7441 gaatggtcat ttattacaga acctaccggt ttgtctacac aagataaaaa tccgacaagt
     7501 gctgttttat aaacaatata tataacttta ttctcgccta tatctgctcc tactccatca
     7561 acattcgtga ttgtcactgg aataacatag ttagtaccca gctgcacaga agccatatca
     7621 tccgaaaaac tcaaggcaac actctcttcc ggagttgttt ttccttgttt aatcattatt
     7681 gtcgattgct tcaaacttgc actagtcagt aaagaataat ctgtgccatg caatgcatta
     7741 tacgttccaa ctaatgccgg attaatagca agagtaactt tggtgtcacc atctgcggcc
     7801 catgccgatt ttaagatacc gtcaagcttc cattcactgc ttaaatttgt aaatccttga
     7861 ctatactgat actctaacag atattcttta cttgaagtca gtgtgacatg atttggtttg
     7921 taagtcgatt caaatgtcaa gaatatctta ctattacttt cactcgctga tactcctgtt
     7981 ccattaatag aagttatagc aatcgggaga atataatttt ccgatccgtt cttaaattct
     8041 tccatattag tataatgcac ttttaaagta tctacagaga tatattcccc ttgttttata
     8101 tacaaagttg cattttccag ttctgcattt tgtaaagcta catagctcgt tccatattca
     8161 ctgttgtatg catctaccaa tgacctgtca atagctaatt ggatggtcaa atcttgtggt
     8221 gcaggtttag tacacctgac aggagacaaa atatgttcgg tggcgatttc tttcaaaaaa
     8281 gttccgtctc ctttatactc taaagtagca tttgtttcac ttggtttata aatatagaca
     8341 taattgatat catacggatc tgttgcttcg tcatcgtcac atgctgtgac taatggcaat
     8401 gacatagcaa aaaatgtact gtataatata tatttaaata atgctttcat atcatactgt
     8461 tttaaattat tgagcaaatg aatatgtttc ccatgtcacc ttttgacggt tttcgttacc
     8521 taggttagaa ttgccaattt ccacatcatg accattaccg gttacatcgt gtagtattgt
     8581 agctccttca ccttcattca ttggcagata caacaacaaa ttcttgtctg tataatcaac
     8641 ttcggtatac atagatttct ttatctgatt aactgtgcgt gtaactttcc aaaaacgaac
     8701 ctgacacatt tcacagaaat ccggaaaata ttcttctcct gaagaaatca tctgaaattg
     8761 atcaatattc atcggttgtc ctattgaaga agataatgag gcaactacag taccattttg
     8821 gtacaataaa gtagtaccgg atgctgcatc ataactcact gcaaaatgat accatttttg
     8881 tgcttctaaa ccttttccct tagttggatc acctgtatca aattgagacc ccatcgtttt
     8941 tacttgtagg aaattatttt tatagctacc attctcggaa tagattaagt caccaaaccg
     9001 tatatatagt tctgtcccta aacctcctga gtttattata gcctgattat tcttagtata
     9061 tccaccgttc cctgatttag aggtgacttt actccaccat tccaatgtat aatttggcaa
     9121 agctaacccc caagctcctt ccggggctgc atgcatacca ttataccatg ttaatttagg
     9181 aacagcttgt ttcaaaggct tcacaagaac caataaaaaa ctggaagagg attccgactt
     9241 ctcaatacct ccttccacat tcttaatact gatgggaatt gcatattgag caccgccttc
     9301 agcttcaaaa cttttaatat caacattcac aggatctgca cttacagaac ctgcttcaat
     9361 tgtcactgat tcaggaaatg atatatattc tttaggaggc attttataat tagtttcatt
     9421 cttcttatta taagcatcta atacagattc gtcaataaat aaattagctt ttattgtttg
     9481 attaataata ttcaccaaac gtacagttaa cgaagtacgc gtcgtaccct ctgtcaatgt
     9541 caattcttta gttttggatg tagacgcttc atttatatag actaaattat ctataacatc
     9601 atacttagca ttttcacatg cagtatggac cagtgccagt accccaaatg ccattatttt
     9661 aagtaaagat attctcttca ttgtttaacc ctttctttta gttattaata ggaggattct
     9721 gtgcagcaat agctgcacgc actgtgggat aatcaggatt tccaggataa tcatactcaa
     9781 tatgataagc ccccatacct gcatgttcta ttccacaagc cggatgatag ctctgttgct
     9841 cggtaaagta atgcttatcc actgctcttt caaaagttgc agtcacaata gatttcccca
     9901 tagcttcttt aaagacatta gggtgacttc tacgtacagc ttcaaagaaa gaatccaatc
     9961 cagaatgtcc tagttcatag gtctgccaag ctatataatc aagacttaga actgtttcct
    10021 ctgaaagcac ttcataaaag ctcaaccaac ctgcaccacc agggatatca gcaaccaaca
    10081 ttttccccgt cttatcaaac tcctcacgta aagtcttcat aaacgcattg ggtactgatg
    10141 gcatactgga gttcattaaa gtcccccaat cctcaatatc ataatcaaat ccatcgatat
    10201 tatatttgtt acatgtatct acaatagcaa gtgcatattt cttagcagcc tcaatgcaag
    10261 attgctcatc tttaggatca aagccccaaa acgcttcctt cactgcatca tcgttacccc
    10321 ccggtgtgag attatcacca atatctcctg cgcgccaaca aagcactgct ctggaaccct
    10381 tagcctgaaa gtcttttaaa tcagcctgtt gctcaaccgt cagatttccc caacagagcc
    10441 aaaggctcac aaaatccgta ctgtccggta atccacataa agcatattgc atggaagaac
    10501 ctcccttacc tgcccagtta ccaaaccagc caaacataat cttatgtgga gagttaaaat
    10561 aatccttcaa attattttca taaccttgcg taggaggttc ataataatct ttcgcctcta
    10621 tgtcggtcca atcactacat gcgatattta agaatccctg cgaaaaaaag agagaaattc
    10681 ctattccgta tattattttt ttcaatttgc tcgttttcat aataaaaatt attttaacgt
    10741 tctgatttaa tttttcttag cccaccaaag atctgtggca gagttatctg caccacctaa
    10801 cattgataca gctgctttca catttgcatt attcgtatta tattctgact gagggaaagg
    10861 caaacgacgc ataccacgct gcactgtcac cccatctgta ttcagattat tcacgatagg
    10921 gaatagttta ggataacctg tacgacgaat gtcagcccac gtttcccaac cattcggaaa
    10981 attggcaatc cacttctgaa tcaaaatacg ctccaaattc tctgtaacac ttgctgattc
    11041 attatatttc ggagttacag ttgacactgc tgctatatcc ttacctgaat ccgaaggatc
    11101 actgtaagca gcaggaacct tttcactttt caaataatcg ccaatagtag ctttacgttc
    11161 ttccatagac actgtcactc ctgcgtcata aagttctttg ggagttcctc ccatattcca
    11221 tttatacatc aatgcagctt ctgcacgtaa aaaataagct tcagatgcag acataatgag
    11281 caattcatca tctataccaa tattcaggcg ggagaatttt gtataatttg cctgagttgt
    11341 agcactttgg taaataccat ttcgcactcc tatttgtcct ccaccgatag aagcatctgc
    11401 ttctgatgca tatttagcca aacgaggatc attataaccg cttaaatatg aagtgatatt
    11461 agcactgata cgaatttcat tccatgaaga agtaacacga taatatggat tcataccgtc
    11521 attatattta ctatatgcag catctgatgc agatgtcatc acaccaatta catcagaaac
    11581 agcttcttct gctttctcct tggcaagtgc tggagaaaca ctagaaatgc gcattgccat
    11641 acgaagcttt aaagaattgg caaatttcac ccatttgtta aaatctccat taaatacaag
    11701 atcgtattct gataaagaac tcatatcttc attacctaac actgctactt taaaagcgga
    11761 aatcgcttca tccaaatcat caaacatgtg tttataaaga tcctccatat tgtcatattc
    11821 tacagtaaaa gcagttcctg taatttgaga ataaggaatc ggtccataac aatcactaat
    11881 tttaagtgaa gctgccacac gaagaatctg tgcccattga taagccaatc ctttgccatc
    11941 agaaagatca cgtatctgga aatatccggt ataaatctgt ggcatagtag tatcaaacat
    12001 atttccatac cacccaactc ttggattgta agtataataa ttacctccat taccccattg
    12061 ggcgatacaa gtaatttctc caccatattc agatccaatc atctgatcca acatctgtga
    12121 attgttctgt tgtccttgta ctaatgcagg aatcatgctt ttaatcaatg atccggtgat
    12181 tgcattatca cccagcattt ggtcaggttt aggtccaaag ggatttgtat tatactcttc
    12241 aaatttatcg gtacaacctg ttcctagtgc tactaacaaa gtatacacag acagttttgc
    12301 aaacttcttt attatcttat tctttttcat aatctaaact agaatgttag tttgacatta
    12361 aatccgagac ttctcaaact aggttgttga aaatagtcaa ccccctgata gaaattacta
    12421 gtgacagaag atgtactttc cggatcataa ggtgctttac aataaatcat ccataaattc
    12481 tttcctgtaa gccccagtgt catatttaca tgatttttga accatgtttt aggaagttgg
    12541 tagctcaagc tcagttcaga aaggcgaata ttcgttgcac tatatgtata ataagtacca
    12601 acagcagtag ttactttact ataatattcc tcagcatcca ctttactgtc tccaacccat
    12661 acaccgcctg cctgacgagc aactgcagaa ctttcagata caccatattt atcaatcatg
    12721 gcttgtgtat ccgatacaac taatcctcca aaacgcccgg tgaatgcaaa tccaagattc
    12781 catcccttcc aagcaacact accattccat cccaaataat atttaggaag aatagagcca
    12841 accttgcggt attccgtatt ttcaatagcc aaacttccat tagaggggtc tttccaaata
    12901 tatccattag gagactgacg caaacgctga ttgatataaa tatctcccat tgatccgttt
    12961 tcatagagtc ttaaagtcgg accaccacta gttcccaatg ttccttttga gtaatactcc
    13021 atttcgatag cttcgccggt ttccggattg atggcaccat tcgctaaact aacgatcttg
    13081 ttttgattaa gagtgtaagt gaaatttgta gataccttca ctttatcaaa tgtatcagaa
    13141 tatcctaaag ccagctcaat accctgattc tgaatattac cagtctgcac aatattattc
    13201 ttatatccag atgaagccga tgcatcaaca tagaatgtct gattgaaggt attagaacga
    13261 tagaaggtca tatctaaatt aatacggttg ccaaggaatt tagcattgac gcctagttcc
    13321 catgattttg tattttctgg tttcagatta gtattataat gacttgcagg atattcatat
    13381 gtatttgttt gctcattata agtatattgc atttgggtaa ggtatcgatt aggggaagaa
    13441 gcgacctccg cccacgaacc acgaactttc aaataagaaa tagcttttgg tagctttaca
    13501 gattcactaa caagccatga cagaccaaca gacggataaa agtaggaacc tttgctggta
    13561 aaagctaatt gagatgccca gtcattacgc ccagtgacag tcaaatacaa ttgatgattc
    13621 catcctaatt ctgcacttgc aaaaacactt tgtacttgat catgccattt tgattcatta
    13681 cgcttggaag tattgacatt aatattgcca taatggaaga aattaggaat ttgctccaat
    13741 cctcccttta gatacatagc atcttcctga atatcattaa tagaagcacc aacagttgca
    13801 ttcaatgaaa gtttgtcatc aaagaaattc ttatttatgc tagccattac atcagcataa
    13861 acagaccgat cattttgttt agtatgtcca taataacctt tagaactact ttctgtaaaa
    13921 gtacctcgtg tactagcata atacttttca taactatcgc tatctgaatt atccacacgt
    13981 actcgccctg ttacattcac ccaatctgtt atatcccatt tcagactagc attaaacata
    14041 taacgacgtt tagaaagctc attctgcatt cgattcataa tccaatatgg gttttgcata
    14101 tccaaatcag taccaaatat agattccggc caatattgta ccataaggtt tcgagcctca
    14161 ctatagcgtt catacatctg tacttcctga aagttttcac ctcgtggaaa aagataaaga
    14221 gataccaagg gattaaaata ttgtccacta cctaccatat tcttattatt ttgaataata
    14281 tattgagctc ccaaatcaag actcaactta ttatcacaga atttagcggt attacgaata
    14341 gagaaattat agcggttata agcattatta ggtaagatac ctgtagagtt tgtagtagag
    14401 acagatgcgt aagtttgatt ttgttcagta ccagtggtca acgtgaaacc attcatctcc
    14461 gtcattcccg tattgaagaa gtcagatgga tcaaagttgc taggagtatc catcaagctc
    14521 ccccaactgc ctaactctcc ttcacgatta ccataaatat tctgaaactt cggcatcatc
    14581 atcggagatg aaaaacttgt actattacta taagaaattt gcacttttcc tacagtacct
    14641 tttttagtag tgataagaat aactccatta gaagcatccg aaccatacaa ggctgcagcg
    14701 gaaggtcctg ttaaaattgt catgctctca atatcttcag gattaatatc agctacgcta
    14761 ttagatcctg gctgtttgtt catcgtacct ccagcattat ctcctgaatt tacattaaac
    14821 attggaatac catcaataac ataaagtgca ttatcatttt tctccaaaga ctttgtacca
    14881 cgcataacta cacgagccgc agccccagca ccggctgaag aagcatttat tgttacgcca
    14941 gctacttttc ctgataaagc attaataaag ttagcatcct ttatattagt caattcatct
    15001 ccctttactt gctgtacatt ataactcaac gctttttgtt cacgtttgat acccaacgca
    15061 gtaactacta cttcgtccaa ggtttgcgtg tcttcaccca t
//
