LOCUS       AE015928               15539 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Bacteroides thetaiotaomicron VPI-5482, complete genome.
ACCESSION   AE015928
VERSION     AE015928.1
DBLINK      BioProject: PRJNA399
            BioSample: SAMN02604314
KEYWORDS    .
SOURCE      Bacteroides thetaiotaomicron VPI-5482
  ORGANISM  Bacteroides thetaiotaomicron VPI-5482
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 15539)
  AUTHORS   Xu,J., Bjursell,M.K., Himrod,J., Deng,S., Carmichael,L.K.,
            Chiang,H.C., Hooper,L.V. and Gordon,J.I.
  TITLE     A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis
  JOURNAL   Science 299 (5615), 2074-2076 (2003)
   PUBMED   12663928
REFERENCE   2  (bases 1 to 15539)
  AUTHORS   Mahowald,M.A., Rey,F.E., Seedorf,H., Turnbaugh,P.J., Fulton,R.S.,
            Wollam,A., Shah,N., Wang,C., Magrini,V., Wilson,R.K., Cantarel,B.L.,
            Coutinho,P.M., Henrissat,B., Crock,L.W., Russell,A.,
            Verberkmoes,N.C., Hettich,R.L. and Gordon,J.I.
  TITLE     Characterizing a model human gut microbiota composed of members of
            its two dominant bacterial phyla
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 106 (14), 5859-5864 (2009)
   PUBMED   19321416
REFERENCE   3  (bases 1 to 15539)
  AUTHORS   Xu,J., Bjursell,M.K., Himrod,J., Deng,S., Carmichael,L.K.,
            Chiang,H.C., Hooper,L.V. and Gordon,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2002) Department of Molecular Biology and
            Pharmacology, Washington University in St. Louis, 660 S. Euclid, St.
            Louis, MO 63110, USA
REFERENCE   4  (bases 1 to 15539)
  AUTHORS   Mahowald,M.A. and Gordon,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2009) Center for Genome Science, Washington
            University in St. Louis, 4444 Forest Park Ave., St. Louis, MO 63108,
            USA
  REMARK    Protein update by submitter
COMMENT     On or before Jan 5, 2006 this sequence version replaced AE016926.1,
            AE016927.1, AE016928.1, AE016929.1, AE016930.1, AE016931.1,
            AE016932.1, AE016933.1, AE016934.1, AE016935.1, AE016936.1,
            AE016937.1, AE016938.1, AE016939.1, AE016940.1, AE016941.1,
            AE016942.1, AE016943.1, AE016944.1, AE016945.1, AE016946.1.
FEATURES             Location/Qualifiers
     source          1..15539
                     /organism="Bacteroides thetaiotaomicron VPI-5482"
                     /mol_type="genomic DNA"
                     /strain="VPI-5482"
                     /type_material="type strain of Bacteroides
                     thetaiotaomicron"
                     /db_xref="taxon:226186"
     gene            complement(1..1179)
                     /locus_tag="BT_1712"
                     /old_locus_tag="BT1712"
     CDS             complement(1..1179)
                     /locus_tag="BT_1712"
                     /old_locus_tag="BT1712"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="AAO76819.1"
                     /translation="MKKVDIIHGGWLKAPNGASSVLRTLAESTSKFEEYGIQLSVYSMD
                     LIVLKSFENIAAINQRKGLRYFIKKNANANSILAFISIYAIYLRHARKIVKYYFDQGLE
                     ESRILFIHDIFTCYYYLKYRSRRQKTVLVLHNNGDTFNMLRQYYPVLNKSRLYSILLYI
                     ERKVLSEVDKVLFVAENPKDTFVQLHPDIPIEKVGFVYNGILSKEMHICPEKHLGPLEI
                     CCVGSVSKRKGQDMIVEALVKMSPVQREKVHFTIVGDGTLRGELEKLCFEKGISKYIDF
                     IGVSNQVENYLLRSDIFMLPSRDEGFPISILEAMRAGLPIISTNIAGIPEMVFSGINGI
                     VISPCLEDIYDILCHIESYNWSAMGKLSYELYQQKFTLDSMIESYANILNAI"
     gene            complement(1192..1686)
                     /locus_tag="BT_1713"
                     /old_locus_tag="BT1713"
     CDS             complement(1192..1686)
                     /locus_tag="BT_1713"
                     /old_locus_tag="BT1713"
                     /note="acylneuraminate cytidylyltransferase-like, with
                     haloacid dehalogenase-like hydrolase domain"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acylneuraminate cytidylyltransferase"
                     /protein_id="AAO76820.1"
                     /translation="MKEIKLILTDIDGVWTDGGMFYDQTGNEWKKFNTSDSAGIFWAHN
                     KGIPVGILTGEKTEIVRRRAEKLKVDYLFQGVVDKLSAAEELCNELGINLEQVAYIGDD
                     LNDAKLLKRVGIAGVPASAPFYIRRLSTIFLEKRGGEGVFREFVEKVLGINLEDFIAVI
                     Q"
     gene            complement(1779..2819)
                     /locus_tag="BT_1714"
                     /old_locus_tag="BT1714"
     CDS             complement(1779..2819)
                     /locus_tag="BT_1714"
                     /old_locus_tag="BT1714"
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid synthase (N-acetylneuraminate
                     synthase)"
                     /protein_id="AAO76821.1"
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
     gene            complement(2819..3568)
                     /locus_tag="BT_1715"
                     /old_locus_tag="BT1715"
     CDS             complement(2819..3568)
                     /locus_tag="BT_1715"
                     /old_locus_tag="BT1715"
                     /note="homolog of spore coat polysaccharide biosynthesis
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="AAO76822.1"
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     gene            complement(3577..4836)
                     /locus_tag="BT_1716"
                     /old_locus_tag="BT1716"
     CDS             complement(3577..4836)
                     /locus_tag="BT_1716"
                     /old_locus_tag="BT1716"
                     /codon_start=1
                     /transl_table=11
                     /product="putative teichoic acid biosynthesis protein B
                     precursor"
                     /protein_id="AAO76823.1"
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     gene            complement(4790..6274)
                     /locus_tag="BT_1717"
                     /old_locus_tag="BT1717"
     CDS             complement(4790..6274)
                     /locus_tag="BT_1717"
                     /old_locus_tag="BT1717"
                     /note="homolog of lipopolysaccharide biosynthesis protein
                     involved in export"
                     /codon_start=1
                     /transl_table=11
                     /product="putative lipopolysaccharide biosynthesis protein"
                     /protein_id="AAO76824.1"
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     gene            complement(6617..7738)
                     /locus_tag="BT_1718"
                     /old_locus_tag="BT1718"
     CDS             complement(6617..7738)
                     /locus_tag="BT_1718"
                     /old_locus_tag="BT1718"
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate pyruvate
                     aminotransferase"
                     /protein_id="AAO76825.1"
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     gene            complement(7748..8872)
                     /locus_tag="BT_1719"
                     /old_locus_tag="BT1719"
     CDS             complement(7748..8872)
                     /locus_tag="BT_1719"
                     /old_locus_tag="BT1719"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfopyruvate decarboxylase subunit beta"
                     /protein_id="AAO76826.1"
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     gene            complement(8889..10190)
                     /locus_tag="BT_1720"
                     /old_locus_tag="BT1720"
     CDS             complement(8889..10190)
                     /locus_tag="BT_1720"
                     /old_locus_tag="BT1720"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate phosphomutase precursor"
                     /protein_id="AAO76827.1"
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     gene            complement(10211..10930)
                     /locus_tag="BT_1721"
                     /old_locus_tag="BT1721"
     CDS             complement(10211..10930)
                     /locus_tag="BT_1721"
                     /old_locus_tag="BT1721"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glucose-1-P-cytidylyltransferase"
                     /protein_id="AAO76828.1"
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     gene            complement(10994..12142)
                     /locus_tag="BT_1722"
                     /old_locus_tag="BT1722"
     CDS             complement(10994..12142)
                     /locus_tag="BT_1722"
                     /old_locus_tag="BT1722"
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein involved in capsular
                     polysaccharide biosynthesis"
                     /protein_id="AAO76829.1"
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     gene            complement(12153..14522)
                     /locus_tag="BT_1723"
                     /old_locus_tag="BT1723"
     CDS             complement(12153..14522)
                     /locus_tag="BT_1723"
                     /old_locus_tag="BT1723"
                     /codon_start=1
                     /transl_table=11
                     /product="polysialic acid transport protein kpsD precursor"
                     /protein_id="AAO76830.1"
                     /translation="MLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQKQLASELARKGVTK
                     EQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLEDHPTTQDLARGDQVF
                     GRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIRQQISPEGTINIQKI
                     GPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNIRTIQINVMGEVVQP
                     GTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVYEFIMKGNTQDDIRL
                     QEGDVVIVPAYDVLVKISGKVKRPMRFEMKKEENLATLIKYAGGFEADAYTRSLRVVRQ
                     NGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAVYRPGIYQLSGKLNT
                     IRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLALMKNDILYI
                     PSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDISRRIKN
                     PRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPGYQAQQNVAIEGEIL
                     FGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLG
                     EAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMV
                     PNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIV
                     PGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     gene            complement(14582..14950)
                     /locus_tag="BT_1724"
                     /old_locus_tag="BT1724"
     CDS             complement(14582..14950)
                     /locus_tag="BT_1724"
                     /old_locus_tag="BT1724"
                     /note="Bacteroides fragilis UpaZ homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="AAO76831.1"
                     /translation="MDAIILQENIEGLLSLVRMLLPGGGSAGCVYLDDLSALQRSIHEK
                     INDLYSQRGETPEQDATLCLAILQGYNVSMYANPEDEERKQAVLTRSLSLLDVLPPSLL
                     KQQLSAVCHGMQELCEIN"
     gene            complement(14961..15539)
                     /locus_tag="BT_1725"
                     /old_locus_tag="BT1725"
     CDS             complement(14961..15539)
                     /locus_tag="BT_1725"
                     /old_locus_tag="BT1725"
                     /note="Bacteroides fragilis UpcY homolog"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transcriptional regulator"
                     /protein_id="AAO76832.1"
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSEESISMNSSPLARGEKVRVIKGPLTGLVGELVNVDGK
                     SKIAVRLNMLGCACVDMPVGYVEPIMAAV"
ORIGIN
        1 tcatatagcg ttcaaaatat tagcataaga ttcaatcatt gaatcaagcg taaatttctg
       61 ttgatatagt tcataagaga gtttacccat tgcactccaa ttataagatt caatatgaca
      121 caagatatca tatatatctt caagacatgg cgaaattaca attccattga tcccggaaaa
      181 aaccatttcc ggaatacctg caatattagt agatataata ggaagtcctg ctcgcatagc
      241 ctccaaaata gaaataggga atccttcatc tctactaggt aacataaaaa tatcactcct
      301 caacaaataa ttttctactt gattcgaaac acctataaaa tctatatatt tagagattcc
      361 tttctcaaaa cacaactttt ctaattcccc ccttaatgta ccatcaccta caatggtaaa
      421 atgcactttc tctctttgaa caggagacat cttcacaaga gcttcaacaa tcatatcttg
      481 ccctttacgt tttgaaacag atcccacaca gcagatttca agtggcccta gatgtttttc
      541 cggacatata tgcatttctt tgctcaaaat gccattataa acaaatccta ctttttcaat
      601 aggaatatct ggatgtaatt gtacaaaagt atctttagga ttctcagcaa caaacaacac
      661 cttatccact tcagataaaa ccttcctttc aatgtataat aatatactat aaagccttga
      721 tttattaagc acaggataat attgtctaag catattaaaa gtatcaccat tattgtgtaa
      781 taccaacacg gttttttgtc ttctagatcg atacttcaaa tagtaataac atgtaaaaat
      841 atcatgtata aacaagattc tcgattcctc aagcccttga tcaaaataat atttaacaat
      901 cttacgagca tgccgcaaat atattgcata aatagaaatg aatgctagta tagaatttgc
      961 attagcattc tttttaataa agtaccgtaa tcctttccgt tgatttatag ctgctatatt
     1021 ttcaaatgac tttaacacaa tcaaatccat tgaataaacc gaaagctgaa taccgtattc
     1081 ttcaaatttt gaagtagatt cagctaaagt cctaagaaca gaactagccc cattaggagc
     1141 cttaagccat ccaccatgaa ttatatctac ctttttcatc ttttacaaca actattgaat
     1201 cacagcaata aaatcttcca aatttatacc aagaactttt tcaacaaatt ctctaaaaac
     1261 accttcacca cctctttttt ctaagaatat agtagacaat ctacgaatat aaaatggagc
     1321 acttgcaggt actccagcta tacctacacg cttaagtaat ttagcatcgt tcaaatcatc
     1381 ccctatatag gccacctgct ccaaattaat ccctaattca ttgcataatt cttctgcagc
     1441 agacaattta tccactactc cttgaaataa ataatcaact tttaacttct ctgctcttcg
     1501 tcgcactatc tcagtttttt cacctgttaa aatacccaca ggaatacctt tattatgtgc
     1561 ccaaaaaata ccagcactat cagatgtatt gaattttttc cattcattac ctgtttgatc
     1621 ataaaacatt ccgccatcag tccaaacgcc atcaatatct gtaagtataa gctttatctc
     1681 tttcattttt ttagtatttt acccttattt attaatcact acttagctta tagcaggcag
     1741 tactctatac cgtaatacaa gttgcagtag gaatatatct attcaataaa atcaggatat
     1801 attatttcat tcgctgatat atcttgttta gcaaaatgac caattacatt ttttttatct
     1861 atccatttat aaccatcacc aggactcagt aaatgaatgt ccgactcttg aataatacta
     1921 cctgctggaa tatattttcg agtggcaata gaacgttcaa gttttatctt agacttctcc
     1981 accccttttt ctatataaag atcttcagta ccaagccaac actctgctat gcgaatatct
     2041 cgaatcatac gattaacccc atctggacct aaagagccaa gctggtctgt tcctttcata
     2101 tgccgatcaa ttgttacatg cttttctata atttccgctc ccatcgctac agcagctgta
     2161 gcagcagaaa tacctattgt atgatcagaa aaacctatct caaacttatt gtaatgcttc
     2221 ttcaaatatg ttattgtacg tagattcaaa ttatttggat gagttggata ctgagataca
     2281 caatgtagaa tagctatatt actatgatat ctcgttatca catctaatgc attgtcaagt
     2341 tctctttgac cagccattcc tgtcgataat ataataggaa tatgagtttc tgctaatgct
     2401 tcaagcaatg gtaagttagt caaatcacga ctagcaactt ttagcctatc cggtgtgaac
     2461 agtttaagca aagacagaca tcctttggca cataacgtct cgataaaatc taatcctaat
     2521 gacttagcat atttataaat ctcaaaatgc gcttgatcat caagctcaag aaaagcacga
     2581 tgttcaccat aagtacgccc aaaagaatta ggattgtcat atatttgatt catttgagaa
     2641 acagccaatt cttctgataa atctctttta gtcattttaa cagcattcat tggcatgaaa
     2701 tccataccaa aaacatcctc atgtacaggt cgtgagatta attcaataat caacttagcc
     2761 aagtcaacag aaccattatg attctgccct atttcaccaa taatataagt attcttcatt
     2821 atttagaatt tttttttatt tgttgtttca tcagttgaat gtattctgca tgtcttcgaa
     2881 catagtctac aatcacttct atcgatattt ccactctttt ttcttgtaaa tccctatata
     2941 ttctctgtgc tacagaaaaa tcttctaacg tatcaatcgt gagtcgaata ttatgatgtt
     3001 ttgacacgac tggagatcct gaaatccatt gaatattaaa aagttcagga tgactatata
     3061 tataattagt aacatgttca cgatacaata aatcatcagt aaatcctata actcgcttca
     3121 gcgcatcaag cgttacaaat tctccccaaa aaccgaaatg agttttaatt gatggagtac
     3181 catcaatatc aaaacttata taatcgttac aagatttcat tgctatttcg accaattgcc
     3241 ttgccgcatg tacatctaaa aatggattat cagaacatat tcggaatata ccctgtatat
     3301 caaaatattc agcaacatca atgaatcgtt ttaaaacatc attctcctca cctctgaagc
     3361 actttacccc taatgcaagt gccttctttt caataggttc attgataaca gaatttgttg
     3421 tagcaataat tactggaata ttcgatatag cagaaagctt atgaaccatt aagtcaagaa
     3481 tcgattgatt accatagaaa ggtttcaata tttttccagg caaacgtgta gaacctaaac
     3541 gtgcctgcac cacaaatgca taattcattt tatttattat atttcattta aaaatatgtc
     3601 acatattctc tttgttgaat tatcatcttg aaattgattc atcaataaag aaatatgacg
     3661 tcgatgttca gcatgaatat ctttcccagc cagaagtccc atcacagcat ctatcaattc
     3721 attataattg taaacaatat cacctgcaca aaaaaattct attggctcaa atgagaaacc
     3781 tcttactcta cgatattctt caatatcgta gaaattaaat atgactggct tatttaccaa
     3841 taaaaaatca aaataggtag aagtataatc agtaatcatt ccatctgaaa atgacaaaag
     3901 atcatacaat ccatatttat atgtttgttc aaaaacaagt atacctttgg gtaaatcttt
     3961 ttttaagact gttttattct gcaaaggatg taatttaaga attaaagccg cattaaactt
     4021 caatagtatt ttcgataact tcaacaaatc acaatcaaca tatccgagta ttgaacgcaa
     4081 attaccttca gtaacagtct cataatcacg aaaagttgga gtataaacta tatatttagt
     4141 tacatcatat cccgcaaatt tcgaaatttc tcttttaata acattgcaat tatttttcga
     4201 tatcaacaaa tcatttctgg gaaatcctaa gactttgaat ttatcatatg agattccaca
     4261 atctattgaa attattctag cacttaaaca agaagtagca atagagtaat caaatgagtt
     4321 acatgttgta ttacgaaatt tatcataaga atgatctccc atatgataat catctttgaa
     4381 tggagtataa taccccaaac aaataatctg ttgagagcgt tttttaaatg aaaaatcata
     4441 ataaaaagta gctgtaaaac atttacttgc tctacaaaaa caaaaaaagg catacaacat
     4501 atccttaaaa gatactttat taaagaaaaa acgtccaaca catgcacata aaaaagtaca
     4561 cctaatatta ggatttatgc cataaatata ttcttgatat tctgaaatac gagaagaatc
     4621 ataaatttca acatatattt tataatattc agcactatct ttttttagca aataatttaa
     4681 cagaacgaga acattatctg acgaataatt tataatatca tatttatctg ttctacaatt
     4741 aggatgagga ataaaataca atgatctact atcaactggc acacaatggt taattatctt
     4801 tactattact tgaaaaatct tttttaatat tttcatctat gtttttagtt ttaatgatca
     4861 atgttaaaat acaaaaaaaa gaatctagct taaaaagaaa agaaagtaaa atatagaagg
     4921 acatcccagt aatacatcca atcacaattt ttactatatc agtttcaaag aaagaaatac
     4981 atataaaaac gatccccccc attatgaaag agagtattaa acttggaaat acatctttaa
     5041 cttgcaactt taaggtcaaa tcaataagag aattagtata atatgtattc aaatatgtcg
     5101 ctatcagaga gtaaataact ctaccccaac acatcacctc aagcccaaat ggaattgaca
     5161 caaaaagaat gaatatagca atcgtctttt ttattatttc aagacgtaac gacagatcag
     5221 atcttccttt aacccataat aaattcaaat taatttggct caaatgatca aacatccaat
     5281 ccaaacataa tatctgtaaa agaataacaa ccccagacca tttatctgtt aacaatagac
     5341 taataatagg attagccaaa acaagtaaac ctaccattaa aggaaaaatt atatatgagg
     5401 ataatctgat ataatttcga tatgcgtttg ttaaacattt atcatcatct tgaatggaac
     5461 ttaaaatagg atacgctact ctagaaacta aagcatttaa attattggaa ggaaaaatag
     5521 caaattgttc tgctcttgta tagtaaccaa gctctacaac agaaaacttt tttcctatta
     5581 caatggtata cagattacga tatactgtat tgataagact tgagatcaat aatttagatc
     5641 cgaaattgaa taatctttca aaagaacttt tggagaaagt atgtaaaggt ttccaatgaa
     5701 ctaaacagta aaacaaaatt gtcaaaatta tactatttaa gagagtttgc caaactaaag
     5761 cccaaacccc gcaaccgaca taagccatcc atattccaat cacgcctgat ataaaagctg
     5821 cacctaatga aattttagat tgagttttaa agtttacaga aataattaat ttcgttctgt
     5881 gaatagccga taaagcattt attatcaacg acaatgctat aaaacgaatt acaagaacta
     5941 aagtcggcat attataaaag tctgcaatca aagaagccga aaaaaacaat ataccataga
     6001 ataatactgc gacaagaata ttaaaataaa agacagtggc aaaatcctct tcagttctat
     6061 cttttttctg gattaaagca tttgtaaaac cgctatctat aaatacttga gcgacttgaa
     6121 gaaaaatagc taacatcccg atcataccat aatccgatgg tagtaacaaa cgagctaata
     6181 ttatttgaat tataaactgt actccttgta aagagaaacg ttctatagcg ctccacatta
     6241 ttcctgatac agttttctgc tttagatttt ccattactta aatacagtat aaaaacaact
     6301 acatttaccg atatcaatta tatttttcca atattctcac taattggtta ttatcttctt
     6361 cgccccttac cgcaattcta atatggtctc tcccactaaa agcaaattac cctacacaaa
     6421 cattatctcc tataactacc gatgcctttt tataagaata aagaactcct aatgcatcac
     6481 ctcaaattaa tattgccata tttgcctact aagcgaaagc tacgaatagg cactccagaa
     6541 ataacacttt ccggatggaa gtgtatacca cgaagggaaa aataaaaatg acgaatcttc
     6601 aataatattt ctgcaatcat gacatcggta atgtgacgtt ataatgattt aatgcagctt
     6661 ttagtacttt aaagaagttc tcaatatcat ctacttctat ctctcctaaa gcacagattc
     6721 taaaagtatc ctcagttgat atcttacctg gataaatcgt aaatccacgc tcataacaat
     6781 aatcatgtat tttctcaaaa tcccagttgg gatcttctgg gtattgaact gagacaacca
     6841 gtcctgactg ccattcacgc tttattacac ttttaagacc aatttcattt atacctgaat
     6901 gaatagcctc aaaaactctt ttgtgacggg caaacttagc ttcttcaccc acttcaaaat
     6961 attcatttaa tgcctgacga gtggcgtaaa tagtttgtac cggtggagta aaatgcattt
     7021 cacctgttct ctcaaaattc tcatactgca aataaagatt acaatagtaa gaacgcttgg
     7081 gatatttttt tgaaaactta atctgttcct cattgcctat aataaaagaa agacctgtca
     7141 tcgcttgaag tcctttttga gcagatgcca tacaaaaatc cacattatct ttctctatat
     7201 caaaaggaat catgcccaaa gaagaagtag tatcgacgac aaatttagcc tgatatttat
     7261 gagctatagc gcccatctcg cgaatagggt tcagaattcc tgtacccgtc tcgtgatgag
     7321 tagtataaac catagctata tcaggatttt cttgcaacac attttccacc accgataaat
     7381 caggacgttc gtaaacggaa aattccaaat taatatgagg caaaccataa tattgacaca
     7441 cttctacagc acgggtacta tatgccccat tattcactat aagcaccctt ttgtcttcag
     7501 gaagaagaga atttagacat atatcaatat tgatggttcc tgagccacaa aataatacag
     7561 cggtatgttt ttccaaattc ccatgagcaa ctctgaccaa atcgtcccga agttgtttca
     7621 tcatacctgc gaattctttc tcgcgaggac aaatatccgg aacaacttgt gccattttta
     7681 cactgtcagt agtagtggca ggcccaggat ttaataatat ttttctttct attttcatcg
     7741 aatatattta ttttaaaaaa tccataaaat gctccttatt ctctatagga gtagtcgtgg
     7801 gacgtcccaa attctcccga gaatctattt taacctttat ttccaacaaa acaggaccac
     7861 ataactttgg aagctgcttc attgcttctt caatttcaac ttttgtacaa acagtataag
     7921 tatgcttata tccgctcccc cggacaatag ccggaatatc taaactaaat cctaaagtag
     7981 gctgtcctcc tacagactcg tgagcaccat tgttaaacaa aatatgataa tagtttttag
     8041 gagataaatc gccaatgtta ctaattgccc ctaaatgcat aataaatgct ccatcaccat
     8101 ccaagcaata aacaggtcta tcttgctttg ctatagcaat acccaaagag attgatgaac
     8161 tatgtcccat agagcctacc gtgagaaaat catgttcatg accttgctct ttcatttctc
     8221 gatattcaaa taactcacga gaaagcttgc cagtagtaga aacgaccact gaattttcag
     8281 gcagataatc cacaactatt tgcaaagcat cctcacgaga taaaggataa ttacatccga
     8341 actctttttg aagtttatat ttgccaaaaa catctttccg aataattatt gcatgaggaa
     8401 tattcttagt ttttgctgat tgtatgatat catggagctg aataaatgca tcattctcat
     8461 ttgaatcaag aattatataa ggaatccgca ttgctttcaa caaatctaaa gttacctcac
     8521 cctgtttttt atgctgaggt tcatcttttg ttcccggttc accacgccag ccaatcatca
     8581 aaagcattgg aaaactgtat acttgttcat ctgcaagaga cagcagagga ttaacagtat
     8641 tacccaagcc ggaattttgc atataaacca caggaacctt acctgatgcc atataataac
     8701 ctgaagcaat tcctacagcc gcaccttcat tagcagctat gatatgtttc tcacgtgaag
     8761 tatggtctgt gatataggca caaatatttt ttagtaatga gtctggaact cctgtaaaaa
     8821 aatcaacgtc atgactcaga aacgtttcat aaactttttc tacgcttaac ataatgatat
     8881 tcctcttttt atttagtacc tggaatcagt tccaatattt cttttatggg catacacagt
     8941 tcgcgcacct ctaaagcacg ttcattctct aatattatct ttgcgacatt catcatagca
     9001 ggataagcgg cacgaagcat atgattagca taaataatta tattcacacc ccaatcacac
     9061 aattcagact cataaatatg atcatatgta gtaggcacaa ccacgatagg tacatgagca
     9121 tactgttttc gaaacgccaa acaaaattct tttatatctt cacccgactt atttttgcta
     9181 tgtatcataa taccgtccgc tcccgcttgg acatatgcaa aagctctctc taaagcatca
     9241 cttaccggct ttcccgctat aaggctctca atacgagcga taatcataaa atcatcagta
     9301 atctgagatg cctttcctgc tttgatctta ttacagaaac cttcgattgt atcttgagtt
     9361 tgaataacat ctgtaccaaa caatgaattc ttttttaatc caactttatc ttcaattatt
     9421 atagctgaaa ttccatgacg ttctaaagtg cgtactgtaa atacgaaatg ttcaatttta
     9481 ccacctgtat ctccatcaaa aataataggt ttagtagtac actccagaat attattcaaa
     9541 tcttgcaatc gggtagttaa atcaaccgcc tcaatatcag gtttaccttt actggttgaa
     9601 tccgtaaggc tactagacca cattccgtca aatacttccc tcttatcccc ttttaatatt
     9661 tcctgatttt caattatcaa gccacatagt ccatcatgag cttccaaaat acgaactacg
     9721 ggtttggcat ttatcaaacg acgaagtgat tttaaacgta catcaggggt tgtacctata
     9781 gccttaatat ctttatccaa agaagatgaa ttaattccca aagtatatgg aatttcgata
     9841 acctttcctc cctgttcatt catcacttca aatacgcgca cacgttcttc acgtaaaggc
     9901 ccggttttcc agtcgtcacc atgaattata tagtcaggtt taatgcgttt gagattctca
     9961 acatagctcc attcttcttg aggaacaact ttacatacgc ctttaatatt ctgaactacc
    10021 tcttttcgtt gttcataggt cagataagga aggcgtttat gctccgcaat agctttatct
    10081 gtaagaagac caattataac atcaccgtat ttagtagcct cattaataat gcggataagt
    10141 cctggatgca taatatccgc agtcatccca atataaactg tcttactcat aatttgatat
    10201 attattttaa ttaacaatac ggaacaatat atttctctgc atattccaaa tctgatatgt
    10261 catcgatttc ataccatttc agcccttcta ctttatgcac ataaacagga gattgagaac
    10321 aagatattcg tagtaattca tactcatatc ccaaattggg ttgttcatca acaatactcg
    10381 cataatcagc acacattatt ttgtaaaagg aaccggatag tttatggatg ccgaccaatt
    10441 cgcctttagc gtttagttta ttcttattga cagaacatga agaaaggcga aaattatcat
    10501 catgttccac ataatactga tcttgaaact ttgtcactgg agttattagc attgcatctg
    10561 ccgcaggaca ctccaataag ctcattattg cttgtttctc aaaaatcaaa tctgactcta
    10621 acaataaaaa atcatcattg cccagaatct cccgcgtatt atataaagta tacatactat
    10681 ttgtttcagc ataacgagga ctaaaacagg tttcaagcat aggatagtct gtcttcaatt
    10741 cttcataaac ttcttgttta tatcctgtac cgattacaat tcgctcaatg tcacatgata
    10801 acaaagtatc aatagaacga actatcattg gaatacctcc cactttgacg aaccctttag
    10861 gtatcaattc tgtatattgg ccaaaacggg ttcccatgcc cgcagccatt atcatagctg
    10921 tacgtatcat tcgtttaata atatagtaag tgaatttaat tgatgtaaga atgttgtaaa
    10981 cgacgtttta gcatcattta tcctgttcta tctccttatt tttcagttct tttctcaagc
    11041 tagccagcag acttttgcca aaaaacaccc acacgagagt accagatacg gacaggaaca
    11101 caaataataa aatataaatt ttgagtccca tacctgaagg tttcaaaggt acaacggcag
    11161 gctcaactac tgcaaagact ggcttttcct cctgtacttt ggctctggat acctgcaact
    11221 gattagcaac ctgactatat atctgataag ccaaactcat gtcgttctgt aaacgctcct
    11281 gctcagcacg tacactttga agaaccacat tatcatgggc gtctacataa tccgcatatt
    11341 ttctttgagc agcataatat tcctgctgac gttctttaaa caaccgttcc aaatacgcac
    11401 agtcttcttt tacttttgaa gttcgatacc caataatata ttcctgtaat ttatgaacga
    11461 cagaatctgc tataaccgca gtgatctgcg gattttgtaa ggtgaccgta atgctcgtta
    11521 tggcggtttt cttatcaatg gatgcactaa tcttcttttt aagaaaatta atcttctcat
    11581 ttacttcttt cgtcaattcg atagttcctt gccgccctcc actggcagga accgtatctt
    11641 ctccgaataa tgatttaact cctcctatta ctatgcccgg aaaacctata agataatccc
    11701 accaaggaga tgactcttca tcgagataag accccaaagt cattttatca tcctttttag
    11761 aaacggagac ttccatttct aaaagttcca ataaaaaagg agttgaagaa acaatatctg
    11821 ctgaaagaga agcgttcaag gcatctgtgc tttcccctat tagagcccca tctcccaaaa
    11881 acgaggcagc aagtccggct aaaccattac ttcccttcgc attacccatt tcaggagaaa
    11941 gggtaacctt tactgtatat tgcttgggaa tgctcaatgc caccactata gcaattatta
    12001 ctcccactcc agcagctttg catagtactc cacgaacagt aataatctta taaaaaatag
    12061 ccatcaagtc tatttccatt tcatcatctt tccttttatc cacttcagaa aacggttctt
    12121 gataagattg cttttcaatc ataataggtc atttatttct ttatcaaatt agcaatagaa
    12181 gcaatcatca ttcccaaaga actgaaggaa gtagcataac ctaaaatatt agctatgttc
    12241 cctttcttct tagccttacc aggcacaata atctcacacc ccggctcaat ctgtttctta
    12301 ccactaccct taaccttcgt cacctgacca ttcatgtaaa caatgaactt cttactcttc
    12361 cttgcattat cagaacagcc accggcctga ttcaggtaat aatccacatt ctttcccttc
    12421 atataagaaa ccgtattcgg aaccatgaca gcaccattga tagttacagt attagtattc
    12481 ttaggtatgg agatcacatc accttcacgt aagacaagat cggcattact tttaggattg
    12541 ctcaaggctt tttccaaatc tattccaacc gtaaaagtat cttcaacacg aatacccaaa
    12601 gagtcaatca tggcttcgcc caattgcctg ctcataaggc gaattacatc acccatacgt
    12661 ttcttttcac tagcgttagc cacacgggtc agtttcgcac cacgcagata ggcataattg
    12721 gtcggaccac cggctttatt cactaaatcg gaaagacgtt cctcacggct ggtcatggcg
    12781 taatttcctc cgaaaaggat ttcaccttca atggctacat tctgttgtgc ctgatagccc
    12841 ggactgcgac ggacataaac ctgatcataa ggctcaagga taaaaccggg ctgaccatct
    12901 attacaaaac catcctttaa agagaaggta tacatctgac caatcgtatc attatccgca
    12961 gtactacgag gattcttgat tcgtctcgat atatcaatac ggacagtaga ggcggcttct
    13021 ttcaagccac cggcctgaat gatcagatcc tcaagtgtca tgttatccgc ataaggatag
    13081 gaatcagggt gggcaacctc accgtgaact gtgacattac cccggtcttc caggtcatgg
    13141 atacttggaa tgtagaggat gtcattcttc attagggcaa ggtttgggga agtgccgtcc
    13201 atgatagact taatgtctat ctgaacaact tcactggtca ggtcttcacg ctggcgatag
    13261 aggacggcac gattcaggaa agcgtcaccg gtcagaccct gagcttcatg gacaagttcg
    13321 cggatcgtgt tcagtttacc gctgagctgg tagataccgg gacgatagac agcgccacgg
    13381 atttccagtt tgtttgtgaa gcggttaagg atggcttcgg cggttactac gtcaccgtta
    13441 cgcattttat aaatgttgta atctatatct ttgactgtgt tgacttcgta ttcctcacca
    13501 ttctgacgga caacacgtaa tgaacgggtg taggcatcgg cttcaaagcc gccggcatat
    13561 ttgattaaag tggcaaggtt ctcttctttc ttcatttcaa aacgcatagg acgttttacc
    13621 ttgccgctga tctttaccaa tacatcataa gcgggaacaa tcacgacgtc accttcctga
    13681 aggcggatgt catcctgtgt gttgcctttc atgataaatt cgtagacgtc gatggtggca
    13741 atattctttc cgttgcgtac caactgaacg tttcggaggc taccgatatc actcacaccg
    13801 cctgcacgat aaagcgcatg gaagacggta gagaaggaag aaagggcgta ggtaccgggc
    13861 tgtacgactt ctcccatcac attaatctga atagtacgga tattacctaa cgtcagacgg
    13921 atgtcggaag ttggatcggt cgtgttgttc agaccgttat atattttatt cagggcgttc
    13981 ttcagatagt cattggcggc agagactgtc ataccgctaa ggttgacagg gccgatcttc
    14041 tgaatgttga tagtaccttc aggagagatt tgctggcgga tcgtgttctg gctcgcaccc
    14101 cagatatcaa tgatgacttc atcaccggga ccaagacggt aattggcagg agtggcaagg
    14161 ttgacactag gctcgaacgt caggttgcgg gtattgaaga tgttacgtcc gaagacctga
    14221 tcaccacggg caaggtcctg agtagtcgga tgatcctcca gcatatcgga agtattcttc
    14281 ttagtctctt cacgcaggcg ggattcgttg atgtccgtgc ccgttgattt cgaggtattt
    14341 acattgttct gctgctcgta tagctgcttc acacgcattg cctgttcttt ggttacaccc
    14401 ttacgggcta gttcggaagc aagctgcttc tgttccttgc cttggcggat gccgtctttt
    14461 acatattcca gtacctgtga gtcactcatg gactgagcca taagcgagcc acttcccagc
    14521 atcaaacaga agagtagaat gctaaaaagt cgttgtattt tcattgacaa ataaaaaagt
    14581 ttcagttgat ttcacacagt tcctgcatcc catgacagac ggcagataac tgttgcttaa
    14641 gaagagaagg gggaagaaca tcgagaagag acagagaacg ggtcaaaaca gcctgttttc
    14701 tttcttcgtc ttccggattg gcgtacatcg acacattata tccctgaagg atggccaaac
    14761 acagggtagc atcctgctcc ggtgtctccc cccgttgaga atataaatcg ttaatctttt
    14821 cgtggatgga tcgttgtaat gctgaaagat catccaaata cacgcagcct gcactccccc
    14881 caccaggaag cagcatacgt accaaactta ataaaccctc tatattttct tgtaaaataa
    14941 tagcatccat atcccttgcc ttaaacagcc gccataatcg gctctacata accgacaggc
    15001 atatcaacac aggcgcatcc cagcatattc aagcgaacag caatcttact tttaccatcc
    15061 acattgacca gttcgccaac aagacccgtc aacggacctt tgatcacgcg aaccttttcg
    15121 ccacgagcca aaggagaact gttcatgctt atcgattctt ccgaataatc aagcatgaaa
    15181 cggaaacgag ccatctgctc gtcaggaatt acagcaggac tactctcgcc gcgcatcacc
    15241 atgtaacggc tgacagtaga aaaactcagg acttccatgc gttccttagg gtcaacgtgt
    15301 acgaagacca tcataggaag caagacggag gtgaccagct tgcgacggtc gctccattgg
    15361 tggaattcct gttgaacggg aacgaaattc tcgataccca tcttgtccag atgctcggaa
    15421 accttctttt catggtgcat ccgaaccaaa gcaacatacc agcgttttga gtgtgctacg
    15481 ccttcccctg tcccattaat aggcccagca tttagtgatt tcttttttct taaaatcat
//
