LOCUS       FP476056               12241 bp    DNA     linear   BCT 27-MAR-2015
DEFINITION  Zobellia galactanivorans strain DsiJT chromosome, complete genome.
ACCESSION   FP476056
VERSION     FP476056.1
DBLINK      BioProject: PRJEB8976
            BioSample: SAMEA3315864
KEYWORDS    .
SOURCE      Zobellia galactanivorans
  ORGANISM  Zobellia galactanivorans
            Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
            Flavobacteriaceae; Zobellia.
REFERENCE   1
  AUTHORS   Thomas,F., Barbeyron,T., Tonon,T., Genicot,S., Czjzek,M. and
            Michel,G.
  TITLE     Characterization of the first alginolytic operons in a marine
            bacterium: from their emergence in marine Flavobacteriia to their
            independent transfers to marine Proteobacteria and human gut
            Bacteroides
  JOURNAL   Environ. Microbiol. 14 (9), 2379-2394 (2012)
   PUBMED   22513138
REFERENCE   2  (bases 1 to 12241)
  AUTHORS   Genoscope -,C.E.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUL-2009) Genoscope - Centre National de Sequencage :
            BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr -
            Web : www.genoscope.cns.fr)
FEATURES             Location/Qualifiers
     source          1..12241
                     /organism="Zobellia galactanivorans"
                     /mol_type="genomic DNA"
                     /strain="DsiJT"
                     /db_xref="taxon:63186"
     gene            complement(1..1590)
                     /locus_tag="ZOBELLIA_209"
     CDS             complement(1..1590)
                     /locus_tag="ZOBELLIA_209"
                     /note="Lipoprotein that probably is involved in the sugar
                     metabolism (possibly the polygalactoses or related sugars);
                     Contains a C-terminal carbohydrate binding module of the
                     family 4 (CBM4); Signal peptide cleaved between the
                     residues 26 and 27; Localized in the outer membrane;
                     Hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="CBM4"
                     /protein_id="CAZ94282.1"
                     /db_xref="GOA:G0L8Z4"
                     /db_xref="InterPro:IPR003305"
                     /db_xref="InterPro:IPR008979"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z4"
                     /translation="MKHILNFTHNRVAALLMVMAIMVFSSCNNDDDGAEEVSSSVRMKT
                     LPKVAYVLGEQLDLSDLVISMQKNGSMVDVPFASFGAENITTDPANGTVLDFSHQQLTI
                     TIGDSGKGLIQAISVTNNVVELEVKTKAKANYVDGQKIDLTGMVVTLVMEDGTKEDVAF
                     DDFGTEIQTVPMNGDIVSVDDSEVMVSYVSTKAKVAQDIEVVPFAPLSGVVTTPPTISE
                     YEIGERLDLEGMVLTFTMSDGQEVVVPFENFEAFELTATPANETKLIATDSEVQVSHAT
                     GLSLAVPITVNPLDVTGMAIETKPEKTLYKDGEVIALKGLTLRLSINGKEDLIVSSEDF
                     AIYEIVTTPAEGEVYVDGTTEIVVTYPDFVDTVSIPLGSETIYESDFTGGLDGWSANQN
                     GGGSVNISAEEGVLVAQDIVPGANPWDVQLFKPSIILEKGAKYKLTTVVKAYPGQGDFW
                     FTLSVGDGTGRDGWQAYDGGGGIWLAGDTEYQTYEKEFTMGSETTTGGRVLLDIGNQTN
                     GIMVQYVKLEKL"
     gene            complement(1600..2625)
                     /locus_tag="ZOBELLIA_210"
     CDS             complement(1600..2625)
                     /locus_tag="ZOBELLIA_210"
                     /note="Signal peptide cleaved between the residues 17 and
                     18; Localized in the outer membrane; Hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical lipoprotein"
                     /protein_id="CAZ94283.1"
                     /db_xref="InterPro:IPR013728"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z5"
                     /translation="MNTRYFIGILSVLFLVSCSNTEPEFDDFDTQTVYFPYQTPARTLI
                     LGNYDQGINEEDNAYRFEITALMTGVYSNDEERKIYFEVDNSLLANVANVKPLPADYYT
                     FESISPVTIASGDTKARIQVQLYDNFFNDTLSFGKVNTTNYVIPLRITQADNIDSVLSG
                     RSFDNVTNPDRANAAHWDILPKDYTLFGIKYMNRFHGNYLRRGRDMITTGTPILGREYN
                     AEFTIDDEIAFVETSGFNKVHLENIIGRGENSSPGNVALELSFDDDTCSISSYKDDPYN
                     VSGTGKFVEGGDTWGGKPRDVIYLDYTYTDVDNSETHAVKDTLVIRDRTAVFEEFEIEL
                     K"
     gene            complement(2689..4416)
                     /locus_tag="ZOBELLIA_211"
     CDS             complement(2689..4416)
                     /locus_tag="ZOBELLIA_211"
                     /function="Transporter activity"
                     /note="Protein probably involved in nutrient binding and
                     belonging to the SusD/RagB family; Gene very often
                     associated with a gene encoding for a TonB-dependent
                     receptor or transducer; Contains a lipoprotein signal
                     peptide cleaved between the residues 19 and 20; Probably
                     localized in the outer membrane; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family lipoprotein"
                     /protein_id="CAZ94284.1"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR012944"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z6"
                     /translation="MKNILKNITLFTLFSSIMACSLVEPVDENLLGEDRLNFDPAFAEG
                     VLLNAYEGLVNQLYFNDAATDDAVNNFLSSYRRMATGEWNAQNPFTNKWGMYEQVLYAN
                     KFITLIDQVEWKRDEETNELFKQRLYGEAVALRALRHFWILQEHGGRGVSGQLLGIPYI
                     SEFLEFDADFNTPRLGFEETVSRIVADFDEALEYLPMDYDGDLAKRPSRYNDTNDDTYQ
                     FVFGKDQDGRINGRIIKAFKAKLYLLAASPAFMNGQGGYYQEAADLLAELLNDIGGLGG
                     LDPNGYYNFYEFPVGTRNFPEVLWRSNASTDMTWVESQHFPPSLNGEGRLNPSQNLVEA
                     FPMLDGFPFSEAHPDYNPENPFENRDMRLQRYILYNGNDLNGRVVSITNDGGVDGIDQI
                     SQRSTRSGYYLKKLLDQKVVISADGSISSSEKINVYVRYTDLFLMLAEAANELGGPDQM
                     VGGMSARNIIGAIRQRAGIGLDNSDAYLSSISSQEDMRNLIRNERRLELCFEGHRLYDL
                     RRWNLFDQTPDAKGLQFDGTNYESFTVEPRLYNANANYAPIPQNEVVRFNLIEQNQGW"
     gene            complement(4436..7285)
                     /locus_tag="ZOBELLIA_212"
     CDS             complement(4436..7285)
                     /locus_tag="ZOBELLIA_212"
                     /function="Receptor and transporter activity"
                     /note="Protein localized in the outer membrane involved in
                     uptake of macromolecules that are too large to diffuse via
                     the outer membrane porins channels or are encountered at
                     very low concentrations; Contains a Plug module (60-151)
                     acting as a channel gate; The signal peptide is cleaved
                     between the residues 26 and 27; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="CAZ94285.1"
                     /db_xref="GOA:G0L8Z7"
                     /db_xref="InterPro:IPR012910"
                     /db_xref="InterPro:IPR023996"
                     /db_xref="InterPro:IPR023997"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z7"
                     /translation="MIRLNILTKLLLGGSLCMLCSLSVTAQTIDSTSTVILENAPNGLE
                     SYLNEDINLGFHTAEKQDIVGSSSTVKPGDFLKYDTTQWVRDALGGRLTGLSGGSSVRG
                     LGEALIVVDGIPGRSIDLLNMEEIEEITILKDANVSALYGSMARNGVIVVTTKRGSTQK
                     QFNISASTGVRLPIRMPNYLNSADYMEYFNEARVNDGLGELYSAEQIQNHRSGTNPYRY
                     PNVDFYDDGNFNPLTPYSNVTADFAGGSENTKFYINLGFKSDGSFQSVNPENDKGAKRF
                     NVRGNIDFKVNDWIKSSLDVVAIIDKNKTSLSNIYASGGLIRPNLYSPLLPISEIDFSA
                     NPELRGIVDAANQYDGFLLGGNQVYNGGAIASIYAGGYQTNMTRMSQVNNAIDFDLSAI
                     TKGLSAKSYVSFDFYNIYNLSVQNKYAVYQPTWNDQNKIVDLVNVRDNDLKDQVESVNT
                     NVFAIRYGFYGLLNYEKQIKDNHFIDASLIGFANNTYVKDEKQSAKNSHVALSLNYNYK
                     KKLYANLSGAYVNSVKLADGNRGKFAPSLGLAYVLSEESSLKESSWLDYLKIRSSIGVI
                     YTDLGIQDYFLYDAIYEQNGGGYNWGDTNGAGYYNASTKILRGQNLGLDFEKRTDYTLG
                     FEALMFKKLWLEANVFQSIMGEKVIRASTLYPDYYSSFRPYSNFNEDQYSGFEVGVNYH
                     TKTENSTFDIGARALYTKSKRTKVDEVYEDEYQNRKGTPVDAIWGLESLGLFGVDDFNE
                     DGSLKGDLPTQYGTVRPGDIKYKNQNGDDVINDQDMVQIGLYGAPWSFGSDFTWSYKAF
                     TLFALFTAEVGRDGILSGDYYRPQGDAKYSEVVKGRWTEATADTATFPRLSSIGNTNNF
                     DKTSTYWMYSNDNFRIQRVQLTFDLPSQLVDKLNMKDINLFTSVSNLAEFSKNKDIREL
                     QLGFDPMFRYFSFGARMKF"
     gene            complement(7323..9131)
                     /locus_tag="ZOBELLIA_213"
     CDS             complement(7323..9131)
                     /locus_tag="ZOBELLIA_213"
                     /function="Transporter activity"
                     /note="Protein probably involved in nutrient binding and
                     belonging to the SusD/RagB family; Gene very often
                     associated with a gene encoding for a TonB-dependent
                     receptor or transducer; Contains a lipoprotein signal
                     peptide cleaved between the residues 19 and 20; Probably
                     localized in the outer membrane; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family lipoprotein"
                     /protein_id="CAZ94286.1"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR012944"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z8"
                     /translation="MRKIFKLVLGICFLGIFASCEDYLDKSIETELTEEEVFKNFDSAQ
                     GFVEEMYAMIVDYSTAAHWQHFHCYAEDAVGIDTWQFDYAIDEGRYWEWQRSGPGSMFD
                     GPTNTNAELPFDRAKLWPSSWAGIRKSNIVIADADSLMTGANQVEKDVILGQAYFFRAF
                     FHHEIMKFWGSIPYIDRVLEDDWKLERPAQWSETALKIDEDFQRAVDLLPVDWDDPDFA
                     PGLKSRGENMFRLTKGAALSLKAKNLLYAASPLMQNSSSTYDYDKELAKRAADTFAEVL
                     KMSRYSLTPWDEYESVFYSTQGRYPYSSEYIFSQAGSVGWFQNFLSTNWQLGAIGQNNL
                     ASFPTHNYIEDNFGMSDGLSCEDSPLYDPANPWENRDPRLYKWIVLDGDQMVENLGAAT
                     GENEVHRYAQFFREGAHRYPNKGNGTRTGYVAKKWFPIGFNNFDNQGVFAWRLHVRLTD
                     VYLMYAEAALVAYGINGKPQGFELSALDAINKIRERAVPDGSLNVRPEYLTSDNAFMDE
                     IRRERAVELSYESHRWMDIRRWKLGTQEKYKLKTEIIFDRNAEGKPINFVERVLRTKVF
                     EDKHYWLPFPKNDTEIYEGFPQNPGW"
     gene            complement(9143..12241)
                     /locus_tag="ZOBELLIA_214"
     CDS             complement(9143..12241)
                     /locus_tag="ZOBELLIA_214"
                     /function="Receptor and transporter activity"
                     /note="Protein localized in the outer membrane involved in
                     uptake of macromolecules that are too large to diffuse via
                     the outer membrane porins channels or are encountered at
                     very low concentrations; Contains a carboxypeptidase
                     regulatory domain (25-99) and the Plug module (115-223)
                     acting as a channel gate; The signal peptide is cleaved
                     between the residues 17 and 18; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="CAZ94287.1"
                     /db_xref="GOA:G0L8Z9"
                     /db_xref="InterPro:IPR000531"
                     /db_xref="InterPro:IPR008969"
                     /db_xref="InterPro:IPR012910"
                     /db_xref="InterPro:IPR014766"
                     /db_xref="InterPro:IPR023996"
                     /db_xref="InterPro:IPR023997"
                     /db_xref="InterPro:IPR027804"
                     /db_xref="UniProtKB/TrEMBL:G0L8Z9"
                     /translation="MRLLVAFILFFPIALTANEYQQELITVSGNVSEADTGLPIIGASI
                     LQQGTTKGVMTDFDGNYSIDVPQDAVLVFSYIGFAKQTVNVDSRTEIDVFMVVEASELD
                     EVVVVGYGTQTKESVVGSISQVTGADLMQSGGVSTVGQALTGRLPGVTTVSSTGRPGDE
                     SPQIFIRGQSSWNGGGQPLILVDGIERSMNDIDSGDIESLSVLKDASATAVFGVKGANG
                     VILITTKRGKEGKAQLSLTASSAIKTLSRIPEKYDSYNSLMVANEAIERTVPVREEAWR
                     NYTPVDIIEKYRNPANDLERSIYPDVDWVDVMQKDFATDYRLNFSVAGGTKSVKYFGAL
                     SYQHVGDIFDAGSFNNGRDYTPNFNYDRFNYRSNIDFDITPTTRLSVNLSGYYGLQNSN
                     QADPQLLYSSIYSLAPNLYTPIYEDGTYGRAITENFELSNPAVILTAKGFTKNHRVQVN
                     SDFVLDQKLDFLLKGLSFTGRLSYDNNFRGGGGVVEENPGGMDNVVYKIYDQDGSAQLV
                     SPVGTNQFDFVLNPWERNGLTIQDWETSRRLFYQLSFNYNRTFAEKHNTTILMLMNREE
                     YAIGSMFPRYREDWVARATYNYDGRYFIDVNGAYNGSEKYGPGYKFELFPSVALGWMVS
                     NEPFMESATWLDKFKIRGSYGVVGDDSAGERWAYLSQWSSGGSAFMNNVSPYGTRSPYT
                     FRMESIIGNPNLQWETSEKANIGFELSVLKNSLSLEVDLFKEDRHDIIVPADSRSVPSF
                     FGFQPADFNIGETTVEGIEISLDYKKQLTQNWDVWSNFAFTKARDEIIYKEDPLLKQSY
                     QKEEGFAIGQPRVNIRGDMLQSWDDVYGATPQENSQETRRPGYYDEIDYNGDGVVNSDD
                     AVPFGYTVRPQNTYNLTLGTGYKNFSFMVQFYGVNNATKNFTDRTFMLETPLFFEYKSD
                     YWSVDNPDGEEVLPAWLGTGGGTDPYRNWYDASFVRLKNIELAYTFKTGKGSSYKVYVS
                     GNDLAYWSDLPDDRQDNTGSTASEYRGDYPTFKRYNIGLNINF"
ORIGIN
        1 ctataatttt tctaacttca cgtactgtac cattataccg ttggtctggt ttccgatatc
       61 caataagacc cggcctccag ttgtggtttc gctacccatg gtaaactcct tttcataagt
      121 ctggtactcg gtatcaccgg ccaaccatat accgccacca ccgtcgtatg cttgccagcc
      181 gtcccttcct gtaccgtcgc ctaccgatag ggtaaaccag aagtctcctt ggccaggata
      241 ggcttttact accgtggtaa gtttatactt ggctcctttt tccaatatta tggaaggctt
      301 gaacaactga acatcccatg gattggcccc tggcacaatg tcttgggcta caagaactcc
      361 ctcttccgcg gagatgttta ccgagccgcc accattttga ttggcgctcc aaccatcgag
      421 tcctcctgta aaatcggact cataaattgt ttcggaacct agcggtatgg aaacggtatc
      481 gacaaaatct ggataagtaa ccactatttc ggtggtgcca tctacatata cttccccttc
      541 ggcgggtgtg gtaacaatct catagatagc aaaatcctca ctcgaaacga taagatcttc
      601 cttcccgttt atcgacaacc ttagggtcaa gcctttaagg gctattacct ccccgtcttt
      661 atacaaggtt ttctccggtt tcgtttctat ggccattccg gttacatcaa gaggattgac
      721 cgtaatagga accgctaagg aaagtcccgt tgcatgcgaa acctgaacct cgctatcggt
      781 agctatcagt ttcgtttcat tggcgggagt ggccgtaagt tcaaaggctt caaaattttc
      841 gaagggaaca accacctctt gaccgtctga catagtaaag gtcaaaacca taccttccaa
      901 atcaagcctt tccccgattt cgtattcgct tatggtcggt ggtgttgtaa caacgccact
      961 taaaggcgca aacggaacca cttctatgtc ttgtgcaacc tttgccttgg tagacacata
     1021 gcttaccata acttcagaat cgtctacgga aacgatatca ccattcattg gaaccgtttg
     1081 aatttccgta ccaaaatcat cgaatgccac atcttccttg gttccgtctt ccattaccaa
     1141 ggttacgacc ataccggtca aatcaatttt ttgaccgtct acataattcg ctttagcctt
     1201 cgttttcact tcaagttcga cgacgttatt ggtaacgctg atggcctgta tcaagccttt
     1261 tccggagtct ccaatggtta tggtaagctg ttgatgtgaa aaatcaagta cggtaccatt
     1321 tgcagggtcg gtagtgatat tttcggcccc aaaggaagca aagggaacat ctaccatact
     1381 gccattcttt tgcatggaaa taacaagatc ggaaaggtcg agctgctcgc ccaatacata
     1441 ggccactttc ggcaaggttt tcatgcgtac gcttgatgat acctcctctg ccccgtcatc
     1501 gtcgttattg cacgaagaaa ataccatgat ggccatgacc atcagtaagg ccgcgactct
     1561 gttatgtgta aaatttagaa tatgtttcat tttccaattt tattttagtt caatttcaaa
     1621 ctcttcaaaa accgccgttc tatccctgat gaccaaggta tccttaactg catgtgtttc
     1681 tgaattgtcg acatccgtat aggtataatc caaataaatg acatctcttg gttttcctcc
     1741 ccaagtatcc ccaccttcga caaatttacc ggtaccactt acgttgtagg ggtcgtcttt
     1801 atagctggaa atagaacagg tatcatcatc gaaggaaagt tccaatgcta cgttaccggg
     1861 gctggagttt tcgcctcgcc caatgatatt ctctaggtgc actttattga atccgctggt
     1921 ttcaacaaag gcgatttcat catcaatggt aaattccgca ttatactccc tacccaatat
     1981 cggtgtaccg gtggtaatca tatccctacc ccttcgcagg tagttgccat gaaatcggtt
     2041 catgtattta ataccgaaaa gggtataatc tttaggaaga atatcccaat gcgcagcatt
     2101 ggccctatcg ggattggtca cgttatcaaa gctacggccc gaaagcacgc tgtcgatatt
     2161 atcggcctgg gtaattctaa gggggatgac ataattcgtc gtattgacct ttccaaaaga
     2221 taaggtatcg ttgaaaaaat tgtcgtacaa ctgcacttgt atgcgagcct tggtatcacc
     2281 ggaagcaatg gttaccggac ttatgctttc aaaagtgtag taatccgctg gtaggggctt
     2341 tacattggcc acgttagcca ataggctgtt atctacttca aaataaattt ttctttcttc
     2401 atcgttcgaa taaacaccgg tcatcaaggc cgtaatttca aaacgatagg cattatcctc
     2461 ctcgttgatt ccttgatcat aattaccaag aattaatgtt ctggcaggcg tttggtatgg
     2521 aaaatagacg gtttgcgtat caaaatcatc aaattcaggt tctgtattgc tacacgatac
     2581 caagaataag actgaaagta taccaataaa atatcttgtg ttcataaaat gaaaaaatta
     2641 aattaacatt ttggccgaag cttaaattta tatcttttaa aaatacccct accaaccttg
     2701 gttttgctca attaaattga accttaccac ttcgttttgt ggaataggcg catagttggc
     2761 attcgcatta tagagccttg gttctaccgt gaaactttca taattagttc catcaaattg
     2821 caatcctttg gcatccgggg tttgatcgaa aagattccac cttcttaaat cgtacaaacg
     2881 atgtccttcg aaacaaagtt ccaaacgacg ctcgttacgg attaaattcc tcatgtcttc
     2941 ttgagagcta atactactca aataggcatc tgaattatca aggccaatac ccgctctttg
     3001 ccttatggcc ccaatgatat ttctagcgga cataccacct accatttggt ctgggcctcc
     3061 caattcatta gctgcttcgg ccagcataag gaacagatcc gtataccgta cataaacgtt
     3121 tattttttct gaactggaaa ttgaaccatc agcacttatt accacttttt gatccaataa
     3181 tttttttaaa taataccctg atcgtgttga acgttgggaa atctgatcaa taccgtcaac
     3241 acctccatcg ttagtaatgc ttaccactct tccatttaga tcattgccgt tatagagtat
     3301 gtagcgctgc aatctcatat ccctattttc aaaaggattc tccgggttat agtcaggatg
     3361 ggcttccgaa aaaggaaaac cgtctaacat tggaaaagct tccactaaat tttgagatgg
     3421 attcagcctg ccttctccat taagagaagg agggaaatgc tggctttcta cccaagtcat
     3481 atcagtagaa gcattgcttc tccaaagtac ttctggaaaa tttcgcgtac ctaccggaaa
     3541 ttcatagaag ttataatacc cattggggtc aagtccgcca aggccaccga tatcatttaa
     3601 aagttccgca agaagatcag cagcttcttg atagtacccg ccttgtccgt tcataaaagc
     3661 aggactggcc gccaacagat acaacttggc cttaaaagct ttgataatcc tgccgtttat
     3721 tctaccgtct tgatctttac cgaaaacaaa ttggtatgta tcgtcatttg tatcgttata
     3781 tctggaaggt ctttttgcca aatcaccatc ataatccatt ggtaaatatt cgagtgcctc
     3841 atcaaaatcg gccacaattc tggaaaccgt ttcttcaaaa cccaacctag gcgtgttgaa
     3901 atcggcatca aattcaagga actcggaaat atatggtata cccaataatt gtcctgaaac
     3961 accacgcccc ccgtgttcct gtaaaatcca aaaatgtcta agggccctaa gggcaaccgc
     4021 ttcgccatat aagcgttgct taaaaagctc attggtctct tcgtccctct tccattctac
     4081 ctgatctatc agggtgatga acttattggc atagagcacc tgctcataca taccccactt
     4141 atttgtaaaa gggttttggg cgttccattc gccggttgcc atcctacggt agctactcaa
     4201 gaagttgttt acggcatcat ccgttgcggc atcattaaaa tagagctgat tcaccagtcc
     4261 ctcatatgca ttgagcaata ccccctcggc aaatgcagga tcaaaattca gacggtcttc
     4321 ccctaacaaa ttttcatcaa cgggttccac caagctacac gccataattg atgaaaataa
     4381 cgtgaaaagg gttatatttt ttagtatgtt cttcatttca attttatttt tcacattaaa
     4441 acttcattct tgccccaaaa gagaaatagc ggaacattgg atcaaaacct agctgtaatt
     4501 ccctaatatc cttgtttttc gaaaattccg ccaaattaga cactgaagta aaaagattga
     4561 tatccttcat attcaatttg tctaccaatt gggaaggtag gtcaaatgtt aactgcactc
     4621 gctgtattct aaagttgtca ttactgtaca tccaataggt agaggtctta tcaaaattgt
     4681 tcgtgttacc aatggaagat agtcttggga acgtagctgt atcagctgta gcttcggtcc
     4741 atctgccctt taccacttcg gagtacttcg cgtctccctg tggtctgtaa taatctccgg
     4801 acaaaatgcc gtccctacct acttccgcag taaagagagc gaacaaagta aatgccttgt
     4861 aagaccacgt aaaatcagac ccaaaactcc aaggcgctcc gtacaatcca atttgcacca
     4921 tgtcttgatc gtttataaca tcgtctccgt tttggttctt atatttaata tcaccaggtc
     4981 gtaccgtacc gtattgtgtt ggcaaatcgc cttttaagct accatcttca ttaaaatcgt
     5041 ccacaccgaa caatcctaaa gactcaagac cccagatggc atctacaggc gtgccttttc
     5101 tattttgata ttcgtcttcg taaacctcat ctacctttgt tctctttgat ttggtgtaca
     5161 atgccctagc ccctatatca aaagtagagt tctccgtttt tgtgtggtag tttacaccga
     5221 cctcaaaacc tgaatactga tcctcgttaa agttactgta aggtctaaac gagctgtaat
     5281 aatcagggta taaggtagag gccctaatta ctttttctcc catgatggac tgaaaaacat
     5341 tggcctctaa ccaaagtttt ttgaacatta atgcttcaaa acctaaggtg taatccgttc
     5401 ttttctcgaa atccaaacct aaattctgac cccgtaagat ttttgtagat gcattgtagt
     5461 aacccgcacc attggtatca ccccaattgt atccccctcc gttttgctca taaatggcat
     5521 catacagaaa ataatcttga atacctaggt ctgtatatat cacaccaatg gatgatctta
     5581 tcttcagata atctaaccaa gacgattctt ttaaagaaga ctcttctgac aatacatatg
     5641 ccaagcccaa ggacggggca aatttacctc tattgccatc ggccaatttt acggagttca
     5701 cgtaggcccc gcttagattg gcgtataatt ttttcttgta attgtaatta aggctaagcg
     5761 ctacatggct gtttttagcg gactgttttt catcctttac ataggtatta ttggcaaatc
     5821 cgattagtga tgcatcgata aaatggttgt ccttaatttg tttttcatag ttcaaaagac
     5881 cataaaaacc atatctgatg gcaaaaacgt tggtgttcac actttcaacc tggtccttaa
     5941 ggtcattatc ccttacgttg accaaatcga caattttatt ttgatcgttc caagtcggtt
     6001 gatacaccgc atacttattc tgaacactta agttataaat gttgtaaaaa tcaaaactca
     6061 cgtagctttt tgccgacagc cctttggtaa tggcactcaa gtcgaaatct atagcattgt
     6121 tcacctgact catacgggtc atgttcgttt ggtagccccc tgcataaata ctagctatgg
     6181 cccccccgtt atacacttgg ttccctccga gaagaaagcc atcatactgg ttggccgcat
     6241 caacaatgcc gcgtaattca ggatttgccg aaaaatctat ctcacttatg ggcaataatg
     6301 gggaatacaa gttaggtcta ataaggcctc ccgaagcgta aatattacta agcgatgttt
     6361 tattcttatc aataatagcc acaacatcta agctactttt gatccaatcg tttactttaa
     6421 aatctatatt accccgtaca ttgaaccgtt tggctccttt gtcattttca ggatttaccg
     6481 actgaaaact accgtctgac ttaaacccta agttaatata gaacttggta ttttcagagc
     6541 cccccgcaaa atctgcggtt acattggaat aaggtgttaa tgggttaaaa tttccatcgt
     6601 cataaaaatc aacatttgga tatctatacg gattagtacc gcttctgtgg ttttgtattt
     6661 gttccgcaga atatagttcg cccaaaccgt cgttgacacg ggcctcgtta aaatactcca
     6721 tataatctgc cgagttcaaa taattgggca tacgaatagg caaccttacc cctgtactgg
     6781 cactaatatt aaactgtttt tgagtggaac ctcgttttgt ggttaccact atgaccccgt
     6841 ttctggccat ggaaccatag agggcggaaa catttgcatc ttttaatatg gttatctcct
     6901 ctatttcctc catattcaat aggtcaatac tacgacccgg gatgccatca accacgatca
     6961 aggcctctcc taatccgcgg acactgctac ctcccgataa acccgttagc cttcccccaa
     7021 gggcatcgcg tacccattgc gttgtatcat actttaaaaa gtcacccggt tttacggtag
     7081 acgaagaccc tacaatatct tgtttttccg cggtgtggaa acctaagttt atatcttcat
     7141 ttaaatagga ctccaaccca ttaggtgcgt tctctaaaat aaccgtactg gtcgaatcta
     7201 ttgtttgcgc cgttaccgat aggctgcata gcatacagag ggatccaccg agcaggagtt
     7261 ttgtaagtat attcaatcgt atcataaaat atggtattgt ctagtggtga aaacagtttt
     7321 aattaccaac ctgggttttg tgggaaacct tcatatattt ctgtatcgtt tttagggaag
     7381 ggcaaccaat agtgcttatc ctcaaaaacc ttggttctta agaccctttc tacaaaattt
     7441 atgggtttgc cttcggcatt ccggtcaaaa attatctcag ttttaagctt gtacttttct
     7501 tgagttccta atttccatct tctaatatcc atccaacgat gcgattcata ggataattct
     7561 accgcccgtt cccgacgtat ttcatccata aaagcgttat cgctggtaag gtattcaggc
     7621 cgcacgttta agctgccatc gggcactgcc ctttctctaa ttttgttaat ggcatcaagt
     7681 gcggatagtt caaaaccttg tggttttcca ttgattccat aagcaaccaa tgccgcttcg
     7741 gcatacatta agtacacatc tgttaatcgt acgtgcagac gccatgcaaa tacaccttga
     7801 ttatcaaaat tgttaaatcc tattggaaac cattttttag ctacgtaacc cgttcttgtt
     7861 ccatttcctt tgttaggata gcggtgtgcg ccttccctaa agaattgggc ataacgatgc
     7921 acctcgtttt cgccggtggc ggcaccaagg ttctctacca tttggtcccc atccaaaaca
     7981 atccatttgt acagccttgg atccctattc tcccaaggat tggccgggtc gtatagcgga
     8041 ctatcttcac aggacaaacc atcactcata ccaaaattgt cttcaatata attatgggta
     8101 ggaaacgaag cgaggttatt ttgaccaatc gcccccaact gccagttggt cgacagaaaa
     8161 ttttgaaacc agccaacaga acctgcctga ctaaaaatat attccgaaga ataagggtat
     8221 ctcccctgcg tagaatagaa aacactttca tactcgtccc aaggggttaa actgtatctt
     8281 gacattttaa gaacctcggc aaaggtatcc gccgcgcgct ttgccaattc tttatcatag
     8341 tcataggtac tactgctatt ttgcatgagc ggactggctg catacagaag gttctttgct
     8401 tttaaggaca aggccgcccc ttttgtaagc ctgaacatat tttcgcctct cgattttagt
     8461 ccgggcgcaa aatcgggatc gtcccaatca accggcagta aatcaacagc tctttgaaaa
     8521 tcttcgtcta ttttaagtgc ggtttccgac cattgcgcag gtctttccaa tttccaatca
     8581 tcctcaagaa cacggtctat atatggaatg cttccccaaa acttcatgat ttcatggtga
     8641 aaaaatgccc taaaaaaata ggcttgcccc aaaatcacat ctttctctac ctggttggcc
     8701 cccgtcatta gactatccgc atcggcaata acaatatttg atttacgaat accggcccag
     8761 ctactcggcc ataatttagc tctgtcaaaa ggtagttccg cattggtatt ggtcggtccg
     8821 tcaaacatac ttcccggacc acttctttgc cattcccagt atcttccctc atcaatagcg
     8881 taatcaaatt gccacgtatc gatacccacg gcatcttcgg cataacaatg aaaatgttgc
     8941 cagtgtgcgg ccgtactgta atctacgatc atggcgtaca tttcttctac aaaaccttgg
     9001 gcactatcaa agtttttaaa gacttcttct tctgtgagtt ccgtctctat tgatttatct
     9061 aggtaatctt cacaagaggc gaatattccc agaaaacata ttcctaatac cagtttgaat
     9121 atcttacgca ttgtctacta tattaaaagt taatgtttag ccctatgtta tatcttttga
     9181 acgtagggta atcacctcta tattcagagg ccgttgaacc tgtgttatcc tgtctatcgt
     9241 caggtaagtc tgaccagtat gccaagtcgt taccgctaac ataaacctta taactacttc
     9301 ctttcccggt tttaaaggtg taggccaact caatattttt aagtcgcacg aaagaagcat
     9361 cataccagtt cctatatgga tcggtgcccc cacctgtacc caaccaggct ggaagtactt
     9421 cctcgccatc gggattatct acactccaat aatcggattt gtactcaaag aaaagcgggg
     9481 tctcgagcat gaacgtccta tctgtaaagt ttttggtagc attgttcacc ccataaaact
     9541 gaaccataaa ggaaaagttc ttatacccgg ttcccaaggt gaggttatag gtgttctgtg
     9601 gccttacggt ataaccaaaa ggaaccgcat catcactgtt tacaaccccg tcaccgttat
     9661 aatctatttc atcataatag ccagggcgtc tggtttcttg actgttctct tgaggggttg
     9721 caccgtagac atcatcccaa gattgtaaca tatcgcccct gatgttgacc ctgggctgcc
     9781 caatggcaaa cccttcttcc ttttgatagc tttgctttaa aaggggatct tctttataga
     9841 tgatttcgtc ccttgccttg gtaaaagcga aattcgacca tacatcccaa ttttgcgtca
     9901 actgtttttt atagtccaag gatatttcaa ttccttcaac cgttgtctcc ccaatattga
     9961 aatctgcagg ctgaaagccg aagaagctgg gaacacttcg ggaatcggcc ggaacgatga
    10021 tatcgtgccg gtcttcctta aaaaggtcca cctctaagga aaggctgttt ttaagtaccg
    10081 atagttcaaa acctatattg gccttttccg atgtttccca ttgcaaattg gggttaccta
    10141 taatactttc cattctaaag gtatatgggg aacgtgttcc gtagggactc acattgttca
    10201 taaatgcact accgccacta gaccattgcg aaaggtaggc ccatctttca ccggcactgt
    10261 catcaccaac aactccgtaa gaccccctaa ttttaaactt gtccaaccaa gtcgccgatt
    10321 ccataaaagg ctcgttgctc accatccaac ccaaggctac ggaagggaaa agctcaaatt
    10381 tatagcccgg cccatatttc tccgacccgt tgtaggcacc gtttacatca ataaaataac
    10441 gtccgtcata attgtaggta gcccgggcca cccagtcctc acgatatctg ggaaacatgc
    10501 ttcctatggc atattcctcc ctgttcatca acattaatat ggtcgtatta tgcttctctg
    10561 caaacgttct gttatagttg aatgaaagct gatagaacaa tcgtctgctc gtttcccaat
    10621 cttgtatggt aagtccgtta cgctcccaag gattcaagac aaaatcgaac tgatttgttc
    10681 caaccggcga aaccaattga gcggacccgt cttggtcgta aattttataa actacgttat
    10741 ccataccacc gggattctcc tctacaactc cgcccccacc tctaaaatta ttgtcataag
    10801 acaggcggcc cgtaaaactc aaccccttaa gaaggaagtc cagtttctgg tctaggacaa
    10861 aatcactgtt cacctgcacc ctatggtttt ttgtaaaacc ttttgccgtt aatattacgg
    10921 cagggttgct cagttcaaaa ttttcagtaa tcgccctacc gtaagtacca tcttcataaa
    10981 taggggtata taggtttggt gccaatgaat aaatactgct gtacaatagc tgtgggtccg
    11041 cttggtttga attctgaaga ccgtagtaac ccgacaagtt aaccgacaag cgtgttgtag
    11101 gcgtaatatc aaaatctatg ttacttctat aattaaatct atcatagttg aaattgggcg
    11161 tataatcgcg tccgttatta aaacttcccg catcaaaaat atcgcctaca tgctgatacg
    11221 aaagtgcacc aaaatattta accgactttg ttccccccgc tacggaaaaa ttcaatctat
    11281 aatctgttgc aaaatccttt tgcatcacat ctacccaatc tacatctgga tagatacttc
    11341 tttccaaatc attggccgga ttacggtatt tttcaataat atctaccggg gtgtaatttc
    11401 tccaagcctc ttcccgaaca ggaaccgttc tttcaatggc ctcattggct accattaaac
    11461 tattgtagga atcatatttt tcaggaattc tagataaggt ctttatggcg gaactggccg
    11521 taagtgaaag ttgggccttt ccctccttcc cccttttggt cgtgatcaat attacaccgt
    11581 tggctccttt tacaccgaat accgcagtgg cagaggcatc ttttaaaacg gacagacttt
    11641 ctatgtcacc agagtctata tcattcatac tccgttcaat gccatcaacc aagatcaaag
    11701 gttgcccccc accgttccaa gaactttggc ctcggatgaa aatttgaggg gattcatccc
    11761 ctggtcgacc tgttgaagag accgtggtca caccgggcaa acgccccgtt aaagcttgac
    11821 ccacagtaga taccccgccc gattgcatta aatcggcacc ggtaacctgt gaaatggagc
    11881 ccacaacact ttccttggtc tgggttccgt aacctacaac gaccacctcg tcaagctcag
    11941 atgcctcaac gaccataaat acatcgattt ccgttctgga atctacatta acggtctgct
    12001 tggcaaaacc gatataactg aataccaaga ccgcgtcttg gggaacgtca atactatagt
    12061 taccatcaaa atccgtcatt acccctttgg tcgttccttg ctgcaatata cttgcaccga
    12121 taatgggcag ccccgtatcg gcttcagata catttccact taccgtaata agttcttgct
    12181 gatactcatt tgccgtaagt gcaataggga aaaacaaaat aaacgctacc aataacctca
    12241 t
//
