LOCUS       CR626927               15347 bp    DNA     linear   BCT 06-FEB-2015
DEFINITION  Bacteroides fragilis NCTC 9343, complete genome.
ACCESSION   CR626927
VERSION     CR626927.1
DBLINK      BioProject: PRJNA46
            BioSample: SAMEA1705957
KEYWORDS    complete genome.
SOURCE      Bacteroides fragilis NCTC 9343
  ORGANISM  Bacteroides fragilis NCTC 9343
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 15347)
  AUTHORS   Cerdeno-Tarraga,A.M., Patrick,S., Crossman,L.C., Blakely,G.,
            Abratt,V., Lennard,N., Poxton,I., Duerden,B., Harris,B., Quail,M.A.,
            Barron,A., Clark,L., Corton,C., Doggett,J., Holden,M.T., Larke,N.,
            Line,A., Lord,A., Norbertczak,H., Ormond,D., Price,C.,
            Rabbinowitsch,E., Woodward,J., Barrell,B. and Parkhill,J.
  TITLE     Extensive DNA inversions in the B. fragilis genome control variable
            gene expression
  JOURNAL   Science 307 (5714), 1463-1465 (2005)
   PUBMED   15746427
REFERENCE   2  (bases 1 to 15347)
  AUTHORS   Cerdeno-Tarraga,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2004) Cerdeno-Tarraga A.M., submitted on behalf of
            the Pathogen Sequencing Unit, Sanger Institute, Wellcome Trust
            Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: amct@sanger.ac.uk
COMMENT     Accession number for plasmid pBF9343 in this genome project:
            CR626928.
FEATURES             Location/Qualifiers
     source          1..15347
                     /organism="Bacteroides fragilis NCTC 9343"
                     /mol_type="genomic DNA"
                     /culture_collection="ATCC:25285"
                     /culture_collection="NCTC:9343"
                     /type_material="type strain of Bacteroides fragilis"
                     /db_xref="taxon:272559"
     misc_feature    <1..>15347
                     /note="PS_8/PS_C non-variable operon; lipopolysaccharide
                     biosynthesis locus; label: PS_C"
     gene            1..888
                     /gene="rmlA2"
                     /locus_tag="BF9343_0968"
     CDS             1..888
                     /gene="rmlA2"
                     /locus_tag="BF9343_0968"
                     /old_locus_tag="BF1011"
                     /note="Identical to previously sequenced Bacteroides
                     fragilis glucose-1-phosphate thymidyl transferase RmlA
                     SWALL:Q9XDK6 (EMBL:AF048749) (295 aa) fasta scores: E():
                     1.5e-114, 100% id in 295 aa, and similar to previously
                     sequenced Bacteroides fragilis glucose-1-phosphate
                     thymidyltransferase RmlA SWALL:Q9RGK4 (EMBL:AF125164) (294
                     aa) fasta scores: E(): 5.4e-106, 92.17% id in 294 aa, and
                     to Bacteroides thetaiotaomicron glucose-1-phosphate
                     thymidylyltransferase BT0463 SWALL:AAO75570 (EMBL:AE016927)
                     (295 aa) fasta scores: E(): 7.8e-102, 88.81% id in 295 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidyl transferase"
                     /protein_id="CAH06749.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0968"
                     /db_xref="EnsemblGenomes-Tr:CAH06749"
                     /db_xref="GOA:Q5LGJ0"
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5LGJ0"
                     /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG
                     IREILIISTPDDLPGFQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCL
                     VLGDNIFYGQGFTRMLNEAVRIAESESKATVFGYWVSDPERYGVAEFDENGNVFSIEEK
                     PQKPKSNYAVVGLYFYPNKVVEVAKSIRPSSRGELEITTVNQNFLSDKELRVQLLGRGF
                     AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIALRKGWISPEKMKALAQPMLKNQY
                     GQYLLKVIDELYVK"
     misc_feature    4..729
                     /gene="rmlA2"
                     /locus_tag="BF9343_0968"
                     /note="Pfam match to entry PF00483 NTP_transferase,
                     Nucleotidyl transferase, score 360.8, E-value 1.3e-105"
     gene            904..1452
                     /gene="rmlC1"
                     /locus_tag="BF9343_0969"
     CDS             904..1452
                     /gene="rmlC1"
                     /locus_tag="BF9343_0969"
                     /old_locus_tag="BF1012"
                     /note="Identical to previously sequenced Bacteroides
                     fragilis dTDP-6-deoxy-D-glucose-3,5 epimerase RmlC
                     SWALL:Q9XDK5 (EMBL:AF048749) (182 aa) fasta scores: E():
                     1.8e-74, 100% id in 182 aa, and to Bacteroides
                     thetaiotaomicron dTDP-4-dehydrorhamnose 3,5-epimerase
                     BT1338 SWALL:AAO76445 (EMBL:AE016931) (182 aa) fasta
                     scores: E(): 7.1e-62, 84.09% id in 176 aa, and to
                     Bacteroides thetaiotaomicron dTDP-4-dehydrorhamnose
                     3,5-epimerase BT0464 SWALL:AAO75571 (EMBL:AE016927) (189
                     aa) fasta scores: E(): 9.7e-60, 82.38% id in 176 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-6-deoxy-D-glucose-3,5 epimerase"
                     /protein_id="CAH06750.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0969"
                     /db_xref="EnsemblGenomes-Tr:CAH06750"
                     /db_xref="GOA:Q5LGI9"
                     /db_xref="InterPro:IPR000888"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI9"
                     /translation="MNIIKTAIEGLVILEPQLFKDDRGYFFESFNQREFEEKVCKTTFV
                     QDNESKSSYGVIRGLHFQKPPFAQSKLVRVIKGAVLDVAVDIRKGSPTFGKHVSVELTE
                     DNHRQFFIPRGFAHGFSVLSEEVIFQYKCDNFYHPEAEGAIAWNDPDLGIEWRVPCKSI
                     ILSKKDRVHPLLKYIILFK"
     misc_feature    910..1437
                     /gene="rmlC1"
                     /locus_tag="BF9343_0969"
                     /note="Pfam match to entry PF00908 dTDP_sugar_isom,
                     dTDP-4-dehydrorhamnose 3,5-epimerase, score 352.9, E-value
                     2.9e-103"
     gene            1471..1992
                     /gene="wcfA"
                     /locus_tag="BF9343_0970"
     CDS             1471..1992
                     /gene="wcfA"
                     /locus_tag="BF9343_0970"
                     /old_locus_tag="BF1013"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative acetyl transferase WcfA SWALL:Q9XDK4
                     (EMBL:AF048749) (173 aa) fasta scores: E(): 4.5e-69, 100%
                     id in 173 aa, and to Lactococcus lactis acetyltransferase
                     Ynca or ll1287 SWALL:Q9CG23 (EMBL:AE006361) (203 aa) fasta
                     scores: E(): 1.1e-14, 41.09% id in 146 aa, and to
                     Pasteurella multocida hypothetical protein Pm1056 pm1056
                     SWALL:Q9CLZ3 (EMBL:AE006146) (203 aa) fasta scores: E():
                     4.3e-14, 46.45% id in 127 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyl transferase"
                     /protein_id="CAH06751.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0970"
                     /db_xref="EnsemblGenomes-Tr:CAH06751"
                     /db_xref="GOA:Q5LGI8"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI8"
                     /translation="MKKLVYDVRKDIIPWNSRITRILFFLNKIPYLRLFSKPLLRKQFN
                     LSNTVQFNSGFFCHAPKLKCGNYVGLSDTFILAYADVVIGNNVSFSFRNMLITSTHDVN
                     DFNKIIASSIVIGNNVWITSNVIILAGVKIGDNTIIGAGSVVTHDIPANVFAAGNPCRV
                     IKSIRFNKNE"
     misc_feature    1711..1734
                     /gene="wcfA"
                     /locus_tag="BF9343_0970"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 2.2, E-value
                     12"
     misc_feature    1807..1860
                     /gene="wcfA"
                     /locus_tag="BF9343_0970"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 11.9,
                     E-value 1.3"
     misc_feature    1861..1914
                     /gene="wcfA"
                     /locus_tag="BF9343_0970"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 19.9,
                     E-value 0.005"
     gene            1985..3520
                     /gene="wzx2"
                     /locus_tag="BF9343_0971"
     CDS             1985..3520
                     /gene="wzx2"
                     /locus_tag="BF9343_0971"
                     /old_locus_tag="BF1014"
                     /note="Similar to Escherichia coli O-antigen flippase Wzx
                     SWALL:AAO39697 (EMBL:AY208937) (464 aa) fasta scores: E():
                     0.00079, 19.65% id in 468 aa, and to previously sequenced
                     Bacteroides fragilis putative flippase Wzx SWALL:Q9XDK3
                     (EMBL:AF048749) (511 aa) fasta scores: E(): 8.6e-198, 100%
                     id in 511 aa, and to Bacteroides thetaiotaomicron putative
                     flippase BT1354 SWALL:AAO76461 (EMBL:AE016931) (513 aa)
                     fasta scores: E(): 2.5e-110, 52.83% id in 511 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative O-antigen flippase"
                     /protein_id="CAH06752.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0971"
                     /db_xref="EnsemblGenomes-Tr:CAH06752"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI7"
                     /translation="MNNSRTAKGLKNAQVALLFYFINLILSFLSRKAFIEHLGAEVLGL
                     NTTLTNILVYLNLAELGIGYAISYALYKPLYEGDKQAVNEIISIQGWLYKRIAIIVIIM
                     SGVILLFFPLFFAKIEIPIWYVYATFLVLLSSSIFSYFFNYKQFVLTADQKEYKLITNV
                     QGFKVVKTILQIVVIVYFCNGYVWWLLLELLMGVITVFVLNSIVRKEYPWLQTSPKIGK
                     DVKDKYPYIIKKTKQLFFHKIANVVLNQTSPIIIYSYTNLTMVAVYGNYMLIISGISLL
                     INSVFSSIGAGIGNLVAEGNQAKIIQVFNELLSSRIWIVSILCFGVYQMSRPFIVLWVG
                     DRFVLDDFYLLLMLLIAFISLTRLVDLFIAAYGLYQDVWAAILEAFLNLGLSILFGYYW
                     GLSGILGGVIVSLVIIALLWKPFFLFKYGFNKNCLNFYFVYMKCVAFALITFYFSIRVI
                     DYIGIGMCTDYSSWILISMLNIFVYTIISFPIFFFFSDGTNRFIKRVINIVFN"
     misc_feature    order(2021..2089,2132..2200,2273..2332,2345..2413,
                     2459..2527,2537..2605,2696..2764,2807..2875,2933..3001,
                     3029..3097,3116..3184,3194..3253,3290..3358,3401..3469)
                     /gene="wzx2"
                     /locus_tag="BF9343_0971"
                     /note="14 probable transmembrane helices predicted for
                     BF1014 by TMHMM2.0 at aa 13-35, 50-72, 97-116, 121-143,
                     159-181, 185-207, 238-260, 275-297, 317-339, 349-371,
                     378-400, 404-423, 436-458 and 473-495"
     gene            3524..4387
                     /gene="wcfB"
                     /locus_tag="BF9343_0972"
     CDS             3524..4387
                     /gene="wcfB"
                     /locus_tag="BF9343_0972"
                     /old_locus_tag="BF1015"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative fucosyl transferase WcfB SWALL:Q9XDK2
                     (EMBL:AF048749) (287 aa) fasta scores: E(): 1.3e-119, 100%
                     id in 287 aa, and to Vibrio cholerae WblA protein
                     SWALL:O87157 (EMBL:AB012957) (281 aa) fasta scores: E():
                     5.7e-19, 32.74% id in 281 aa, and to Escherichia coli
                     putative fucosyltransferase WbgN SWALL:Q8VQ46
                     (EMBL:AF461121) (290 aa) fasta scores: E(): 6.4e-12, 37.01%
                     id in 181 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT11"
                     /protein_id="CAH06753.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0972"
                     /db_xref="EnsemblGenomes-Tr:CAH06753"
                     /db_xref="GOA:Q5LGI6"
                     /db_xref="InterPro:IPR002516"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI6"
                     /translation="MLYVILRGRLGNNLFQIATAASLTQNFIFCTVNKDQERQVLLYKD
                     SFFKNIKVMKGVPDGIPYYKEPFHEFSRIPYEEGKDLIIDGYFQSEKYFKRSVVLDLYR
                     ITDELRKKIWNICGNILEKGETVSIHVRRGDYLKLPHALPFCGKSYYKNAIQYIGEDKI
                     FIICSDDIDWCKKNFIGKRYYFIENTTPLLDLYIQSLCTHNIISNSSFSWWGAWLNENS
                     NKIVIAPQMWFGISVKLGVSDLLPVSWVRLPNNYTLGRYCFALYKVVEDYLLNILRLIW
                     KRKKNM"
     misc_feature    3524..4282
                     /gene="wcfB"
                     /locus_tag="BF9343_0972"
                     /note="Pfam match to entry PF01531 Glyco_transf_11,
                     Glycosyl transferase family 11, score 34.4, E-value
                     1.1e-10"
     misc_feature    3947..3970
                     /gene="wcfB"
                     /locus_tag="BF9343_0972"
                     /note="PS00017 ATP/GTP-binding site motif A (P-loop)."
     gene            4363..5523
                     /gene="wcfC"
                     /locus_tag="BF9343_0973"
     CDS             4363..5523
                     /gene="wcfC"
                     /locus_tag="BF9343_0973"
                     /old_locus_tag="BF1016"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative glycosyl transferase WcfC SWALL:Q9XDK1
                     (EMBL:AF048749) (386 aa) fasta scores: E(): 1.5e-151, 100%
                     id in 386 aa, and to Clostridium acetobutylicum
                     glycosyltransferase CAC2313 SWALL:Q97GQ3 (EMBL:AE007732)
                     (377 aa) fasta scores: E(): 7.1e-24, 32.44% id in 336 aa,
                     and to Bacillus halodurans hypothetical protein BH3712
                     BH3712 SWALL:Q9K6L7 (EMBL:AP001519) (395 aa) fasta scores:
                     E(): 4.8e-10, 23.75% id in 362 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="CAH06754.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0973"
                     /db_xref="EnsemblGenomes-Tr:CAH06754"
                     /db_xref="GOA:Q5LGI5"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI5"
                     /translation="MEKKEEYVKKKMTLIVNHPWNDVFEGKDVFLVPCYIGKIYHYDVK
                     IVFPSNYLYEAKTIRDVELVPVSYIKKLRPFSFVFGFKLMRYLFCNARKIDLFMRFHVT
                     ITTAIMIIIYKMLNRNGIAYIKLDSNGVMNFEYKNNLKSLFRKLLYRRMFELVDFVSYE
                     TKMGLENITQQTIGIDISSKLFYMPNGFDEDMIKHLDINVKEYSDKENVMITVGRLGTN
                     QKNTELFLKAVENIDLKDWVIYLIGDIDPQNITFLEFVSNFFSNHPEKKKSVIFTGAIS
                     DKRHLWEYYNKSKVFVLTSRCESYGLVLNEAKRFRNFIVSTNVGAFEDLVESGKYGCEI
                     PQDNTDYLACILEKIILGQLDIDVYNDFSPESLSYYYQVKRMKLNN"
     misc_feature    4651..4704
                     /gene="wcfC"
                     /locus_tag="BF9343_0973"
                     /note="1 probable transmembrane helix predicted for BF1016
                     by TMHMM2.0 at aa 97-114"
     misc_feature    4948..5487
                     /gene="wcfC"
                     /locus_tag="BF9343_0973"
                     /note="Pfam match to entry PF00534 Glycos_transf_1,
                     Glycosyl transferases group 1, score 50.4, E-value 3.5e-12"
     gene            5541..6197
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
     CDS             5541..6197
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /old_locus_tag="BF1017"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative acetyl transferase WcfD SWALL:Q9XDK0
                     (EMBL:AF048749) (218 aa) fasta scores: E(): 2.5e-87, 100%
                     id in 218 aa, and to Aeromonas hydrophila acetyl
                     transferase SWALL:Q8KXE9 (EMBL:AF343089) (199 aa) fasta
                     scores: E(): 5.1e-21, 45.34% id in 161 aa, and to Aeromonas
                     hydrophila O-acetyl transferase SWALL:Q8KNM6
                     (EMBL:AF148126) (199 aa) fasta scores: E(): 6e-21, 45.34%
                     id in 161 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="CAH06755.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0974"
                     /db_xref="EnsemblGenomes-Tr:CAH06755"
                     /db_xref="GOA:Q5LGI4"
                     /db_xref="InterPro:IPR001451"
                     /db_xref="InterPro:IPR011004"
                     /db_xref="InterPro:IPR018357"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI4"
                     /translation="MIYYLFRPCLYVCKMFLNYFVCFTSKICTENRYNYFKRIKPFLFS
                     RIVRTWFGHVGDKISIVPPFYIRGGKYIQLGTNFRALSGLRLEAIDFYNNSSYHPSIVI
                     GDNVVFNNSCHIGATNRIIIGNDVVVASRVFITDHFHGNTTYNDLQIPVRNRLLYSKGP
                     VVIGNNVWIGEGASILPNVTIGDNSIVAAHAVVTKNIPANSIAVGCPARIIRTIN"
     misc_feature    5841..5894
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 15.8,
                     E-value 0.091"
     misc_feature    5901..5954
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 11.5,
                     E-value 1.8"
     misc_feature    6027..6080
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 14.7,
                     E-value 0.19"
     misc_feature    6054..6140
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /note="PS00101 Hexapeptide-repeat containing-transferases
                     signature."
     misc_feature    6081..6134
                     /gene="wcfD"
                     /locus_tag="BF9343_0974"
                     /note="Pfam match to entry PF00132 hexapep, Bacterial
                     transferase hexapeptide (three repeats), score 15.7,
                     E-value 0.094"
     gene            6198..7304
                     /gene="wzy2"
                     /locus_tag="BF9343_0975"
     CDS             6198..7304
                     /gene="wzy2"
                     /locus_tag="BF9343_0975"
                     /old_locus_tag="BF1018"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative polymerase Wzy SWALL:Q9XDJ9 (EMBL:AF048749) (365
                     aa) fasta scores: E(): 1.9e-133, 99.18% id in 368 aa, and
                     to Clostridium perfringens capsular polysaccharide
                     biosynthesis protein CPE0478 SWALL:Q8XN60 (EMBL:AP003186)
                     (355 aa) fasta scores: E(): 0.00013, 24.8% id in 379 aa,
                     and to Shigella boydii O-antigen polymerase Wzy
                     SWALL:Q93CS5 (EMBL:AF402314) (350 aa) fasta scores: E():
                     0.00029, 23.67% id in 376 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide polymerase"
                     /protein_id="CAH06756.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0975"
                     /db_xref="EnsemblGenomes-Tr:CAH06756"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI3"
                     /translation="MNLFVLLFVFVFGIIGSYSSKFSEKNLFWLFVIVLAIIIGGRSIS
                     VPDTDQYLEFYQLTLSSSILDIPLYSYEIGFQLLTKILKLITNGSSFFYFGIIVLINSY
                     FLFKSFSCFTDQSYPSKKSSGTLINQIKLQEFLLLYFSYWGLYYTGIVLRAGIAMSILI
                     YLSTLLCSPYISLKKWSAIFLLAIISCSFHITALLGIIALIIFYISKKMTMRSYLLLFL
                     LICIILFGKVSFWIVDMLDRNMPMIFSLIEDTDFAKLQAYSNIDASIKISFRFLFCLLI
                     GLFFIICKRMPLYYYKYLNVYIVGLFLGALFSAIEAFSRIMDFFVIYSFILISMRLSTI
                     NSFKIRFSIMFSIVLIQLLFVYRIIIGL"
     misc_feature    order(6207..6257,6276..6335,6450..6518,6603..6671,
                     6741..6809,6846..6914,7008..7061,7080..7148,7158..7217,
                     7236..7295)
                     /gene="wzy2"
                     /locus_tag="BF9343_0975"
                     /note="10 probable transmembrane helices predicted for
                     BF1018 by TMHMM2.0 at aa 4-20, 27-46, 85-107, 136-158,
                     182-204, 217-239, 271-288, 295-317, 321-340 and 347-366"
     gene            7301..8176
                     /gene="wcfE"
                     /locus_tag="BF9343_0976"
     CDS             7301..8176
                     /gene="wcfE"
                     /locus_tag="BF9343_0976"
                     /old_locus_tag="BF1019"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative glycosyl transferase WcfE SWALL:Q9XDJ8
                     (EMBL:AF048749) (291 aa) fasta scores: E(): 3.3e-118, 100%
                     id in 291 aa, and to Methanosarcina acetivorans
                     glycosyltransferase ma2170 SWALL:Q8TNV8 (EMBL:AE010903)
                     (350 aa) fasta scores: E(): 6.5e-08, 27.1% id in 214 aa,
                     and to Archaeoglobus fulgidus glycosyl transferase af0321
                     SWALL:O29924 (EMBL:AE001082) (324 aa) fasta scores: E():
                     8.2e-08, 26.8% id in 235 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2|GT2_Glycos_transf_2"
                     /protein_id="CAH06757.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0976"
                     /db_xref="EnsemblGenomes-Tr:CAH06757"
                     /db_xref="GOA:Q5LGI2"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI2"
                     /translation="MNNHIKRKAVSVVIVTFNSENLIMDCLDSIFKYNDISDDLEVVLV
                     DNCSKNYLSMFGSIEEKYGNKVVLINNKVNGGYGQGNNLGVEVAKAPIILIMNPDVRLV
                     KPIFKRILSLFERRNIAIAGMQQYESLLKRSQSFLMLREDLCSLFLYAVYTKINKFNEK
                     YFCISGACFAVRKSVFTKVGMFDEQMFLYGEERMLHYKILRLGNYHIVYDSTIGYLHPK
                     ENREFSSKNFLLGYHSFIYTCDKLGLDLHRSRNKMLNMYRFLEFYSWARGDKLKVKYYK
                     EIIKLIKNNI"
     misc_feature    7331..7849
                     /gene="wcfE"
                     /locus_tag="BF9343_0976"
                     /note="Pfam match to entry PF00535 Glycos_transf_2,
                     Glycosyl transferase, score 80.4, E-value 3.1e-21"
     gene            8185..9462
                     /gene="wcfF"
                     /locus_tag="BF9343_0977"
     CDS             8185..9462
                     /gene="wcfF"
                     /locus_tag="BF9343_0977"
                     /old_locus_tag="BF1020"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative UDP-glucose-6 dehydrogenase WcfF SWALL:Q9XDJ7
                     (EMBL:AF048749) (425 aa) fasta scores: E(): 4.5e-161, 100%
                     id in 425 aa, and to Escherichia coli putative
                     udp-glucose-6-dehydrogenase wbqA SWALL:AAO39690
                     (EMBL:AY208937) (426 aa) fasta scores: E(): 4.4e-92, 53.27%
                     id in 428 aa, and to Shigella sonnei ORF1s wbgt or ORF1G
                     SWALL:Q9S0U5 (EMBL:AB028135) (437 aa) fasta scores: E():
                     1.1e-91, 56.6% id in 424 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative UDP-glucose-6 dehydrogenase"
                     /protein_id="CAH06758.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0977"
                     /db_xref="EnsemblGenomes-Tr:CAH06758"
                     /db_xref="GOA:Q5LGI1"
                     /db_xref="InterPro:IPR001732"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR014026"
                     /db_xref="InterPro:IPR014027"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR017476"
                     /db_xref="InterPro:IPR028359"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI1"
                     /translation="MEELKIAVIGLGYVGLPLARLFSTKYECIGFDLNQSRVDALNSGH
                     DMTLEVSDDLLRKALENGFKCTSNIDEISNCNFYVVAVPTPVDLNNRPDLTPLIGASTT
                     VGKVISKGDIVVYESTVYPGVTEEECLPVVEEVSGLTYNVDFYAGYSPERINPGDKEHT
                     VEKIKKVTSGSTPEIADIVDSVYNSVLVNGTHKAPSIKVAEASKIIENSQRDVNIAFMN
                     ELSKIFNAMGIDTNDVIEAASSKWNFIKLKPGLVGGHCISVDPYYLIQKAQVYGVLPRI
                     MSAARRLNDGMGDYVANQVIRLMNKKGILVKDSKILLLGFTFKEDCPDIRNTKVIDIYS
                     TLHEYTSDITVYDAWANSAKVAHEYGISILTAGLDNLVGQFDAVVLCVGHKEFRHMNIR
                     GFLRSDMGVVYDVKAVLSKDIIDGRL"
     misc_feature    8194..8757
                     /gene="wcfF"
                     /locus_tag="BF9343_0977"
                     /note="Pfam match to entry PF03721 UDPG_MGDP_dh_N,
                     UDP-glucose/GDP-mannose dehydrogenase family, NAD binding
                     domain, score 199.6, E-value 4.2e-57"
     misc_feature    8782..9066
                     /gene="wcfF"
                     /locus_tag="BF9343_0977"
                     /note="Pfam match to entry PF00984 UDPG_MGDP_dh,
                     UDP-glucose/GDP-mannose dehydrogenase family, central
                     domain, score 129.9, E-value 4.1e-36"
     misc_feature    9133..9420
                     /gene="wcfF"
                     /locus_tag="BF9343_0977"
                     /note="Pfam match to entry PF03720 UDPG_MGDP_dh_C,
                     UDP-glucose/GDP-mannose dehydrogenase family, UDP binding
                     domain, score 63.8, E-value 3.2e-16"
     gene            9449..10582
                     /gene="wcfG"
                     /locus_tag="BF9343_0978"
     CDS             9449..10582
                     /gene="wcfG"
                     /locus_tag="BF9343_0978"
                     /old_locus_tag="BF1021"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative glycosyl transferase WcfG SWALL:Q9XDJ6
                     (EMBL:AF048749) (377 aa) fasta scores: E(): 3.9e-157, 100%
                     id in 377 aa, and to Bacteroides fragilis putative
                     glycosyltransferase wcgE SWALL:Q9RGJ7 (EMBL:AF125164) (363
                     aa) fasta scores: E(): 5.9e-09, 29.68% id in 219 aa, and to
                     Bacteroides thetaiotaomicron putative glycosyltransferase
                     BT2938 SWALL:AAO78044 (EMBL:AE016938) (408 aa) fasta
                     scores: E(): 6.9e-08, 26.1% id in 249 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="CAH06759.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0978"
                     /db_xref="EnsemblGenomes-Tr:CAH06759"
                     /db_xref="GOA:Q5LGI0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q5LGI0"
                     /translation="MADYNSSICCIFNIGTHYRNPIYSKMSSELPCDFYFGDRLLTPIK
                     KMDYTQLNHFRSELHNKYLFSQFYWQSKSVRLVFKPYTYYVLDGEPYCLSSWVILFWAK
                     LLNKRTVAWTHGWYGRESIVKKVIKKLFYSLFSELMVYGEYAISLMSKEGFDKSKMVCI
                     ANSLDYDNQLKIRLNLSPSSIYSTHFSNSYPVLFYIGRVQKSKKLEYIIQAMDILKQKG
                     FPVNLVVVGKDVDGVHLDCEIAKYNLGSHVWLYGPCYDEMRIGEMFYNADVCVSPGNVG
                     LTAIHSLTYGCPVITHNNFPFQGPEFESIIQGKTGDFFQENDVNSLADTIQKWLSQNLH
                     SREAIRQFAYQTIDTKWNLYYQMNILKQVFLKQAKDE"
     misc_feature    9986..10504
                     /gene="wcfG"
                     /locus_tag="BF9343_0978"
                     /note="Pfam match to entry PF00534 Glycos_transf_1,
                     Glycosyl transferases group 1, score 58.4, E-value 1.4e-14"
     gene            10575..11354
                     /gene="wcfH"
                     /locus_tag="BF9343_0979"
     CDS             10575..11354
                     /gene="wcfH"
                     /locus_tag="BF9343_0979"
                     /old_locus_tag="BF1022"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative deacetylase WcfH SWALL:Q9XDJ5 (EMBL:AF048749) (259
                     aa) fasta scores: E(): 1.9e-113, 100% id in 259 aa, and to
                     Leptospira interrogans polysaccharide deacetylase-like
                     protein la1638 SWALL:Q8F5M9 (EMBL:AE011341) (287 aa) fasta
                     scores: E(): 6.7e-08, 26.8% id in 235 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="CE4|CE0"
                     /protein_id="CAH06760.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0979"
                     /db_xref="EnsemblGenomes-Tr:CAH06760"
                     /db_xref="GOA:Q5LGH9"
                     /db_xref="InterPro:IPR002509"
                     /db_xref="InterPro:IPR011330"
                     /db_xref="UniProtKB/TrEMBL:Q5LGH9"
                     /translation="MNDFRSLIRNSVLDILGIFSRPQNGIHILNGHMICRGVANDQAKY
                     YFSYQLKELSRHVRFIRVEEATSLILNHESVDEPLVAFTFDDGFMECHSMIAPVLEQFG
                     VNAAFFINPNFANGDDVYIQNFTNNIVLTPGKTPMRWKEIRDLHERGHIIGAHTMDHYM
                     INDSNWVELDKQIGCCKSVIEQELSTSCEYFAFPYGRLEHANQSSIDIACKYYKYVFSQ
                     SDYKHYFSFGGRVINRRHFEPFWPVKHVSYFLSCHKK"
     misc_feature    10791..11231
                     /gene="wcfH"
                     /locus_tag="BF9343_0979"
                     /note="Pfam match to entry PF01522 Polysacc_deacet,
                     Polysaccharide deacetylase, score 124.2, E-value 2.1e-34"
     gene            11394..12632
                     /gene="wcfI"
                     /locus_tag="BF9343_0980"
     CDS             11394..12632
                     /gene="wcfI"
                     /locus_tag="BF9343_0980"
                     /old_locus_tag="BF1023"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative glycosyl transferase WcfI SWALL:Q9XDJ4
                     (EMBL:AF048749) (407 aa) fasta scores: E(): 3.2e-164, 99.5%
                     id in 407 aa, and to Vibrio cholerae O37
                     glysosyl-transferase SWALL:Q8L354 (EMBL:AF390573) (409 aa)
                     fasta scores: E(): 4.7e-22, 27.07% id in 325 aa, and to
                     Rickettsia prowazekii hypothetical protein Rp336 rp336
                     SWALL:Q9ZDJ2 (EMBL:AJ235271) (407 aa) fasta scores: E():
                     7.6e-20, 27.81% id in 338 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT4"
                     /protein_id="CAH06761.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0980"
                     /db_xref="EnsemblGenomes-Tr:CAH06761"
                     /db_xref="GOA:Q5LGH8"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q5LGH8"
                     /translation="MITTIVKTLFQINVVANSGSTGHIAEELGRLVIASGWKSYIAYGR
                     WACPSQSMLIRVGTRFDLFVHGLKSMFFDRHGFGSRRATLHLISKIEKIKPDIIHLHNL
                     HGYYLNCEVLFDYLSTAKIPVVWTLHDCWSFTGHCVHFQNIGCEKWKTGCFACPNIRDY
                     PKALGCDNSRMNFIEKKRLFTSVERMMIVPVCNWLSDMLSKSYLSQIKRQTIVNGIDLE
                     MFTPKGNRDVIKSNLGVGTRYMILAVATVWGITKGFDDLIYLNSLLPDKSVIVVVGVTT
                     KQIKKLPGNMIGIERTENTSQLVEIYSAADIFINPTYQDTLPTVNIEALACGTPVITYD
                     TGGSADIVDSDTGMVLKRGDIHTLLEKILEIRERGKESYIIKCRQRALQFFDKSKQLSY
                     YLSLYDQLLNKER"
     misc_feature    11940..11969
                     /gene="wcfI"
                     /locus_tag="BF9343_0980"
                     /note="PS00339 Aminoacyl-transfer RNA synthetases class-II
                     signature 2."
     misc_feature    12078..12563
                     /gene="wcfI"
                     /locus_tag="BF9343_0980"
                     /note="Pfam match to entry PF00534 Glycos_transf_1,
                     Glycosyl transferases group 1, score 63.1, E-value 5.2e-16"
     gene            12649..13413
                     /gene="wcfJ"
                     /locus_tag="BF9343_0981"
     CDS             12649..13413
                     /gene="wcfJ"
                     /locus_tag="BF9343_0981"
                     /old_locus_tag="BF1024"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative glycosyl transferase wcfJ SWALL:Q9XDJ3
                     (EMBL:AF048749) (254 aa) fasta scores: E(): 2.6e-99, 100%
                     id in 254 aa, and to Helicobacter pylori J99 putative
                     jhp0094 SWALL:Q9ZMX1 (EMBL:AE001448) (260 aa) fasta scores:
                     E(): 1.4e-42, 47.6% id in 250 aa, and to Helicobacter
                     pylori hypothetical protein Hp0102 hp0102 SWALL:O24928
                     (EMBL:AE000532) (259 aa) fasta scores: E(): 7e-42, 46.98%
                     id in 249 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="GT2|GT2_Glycos_transf_2"
                     /protein_id="CAH06762.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0981"
                     /db_xref="EnsemblGenomes-Tr:CAH06762"
                     /db_xref="GOA:Q5LGH7"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q5LGH7"
                     /translation="MKISLVTVTFNSAKTLCDTIHSVLSQSYTNIEYIIVDGLSNDETV
                     TLIKEYEPLFQGRLKWISEKDKGLYDAMNKGIRMSTGDIVGIINSDDFYHRGDVLEKVA
                     ESFEAGETEAIYGDVRFVNPDNLDRTVRYYSSKRFVPSLFRFGFMPAHPTFFTYRKYFD
                     QFGYYKTNYKIAADYELLVRFLYVHRLKSKYLPLDFMKMRTGGASTASIKSNILLNKEI
                     VRACKENGIWTCYPLLLLKYLVKVFELIFIKK"
     misc_feature    12658..13134
                     /gene="wcfJ"
                     /locus_tag="BF9343_0981"
                     /note="Pfam match to entry PF00535 Glycos_transf_2,
                     Glycosyl transferase, score 114.4, E-value 1.9e-31"
     gene            13410..14429
                     /gene="wcfK"
                     /locus_tag="BF9343_0982"
     CDS             13410..14429
                     /gene="wcfK"
                     /locus_tag="BF9343_0982"
                     /old_locus_tag="BF1025"
                     /note="Similar to previously sequenced Bacteroides fragilis
                     putative epimerase/dehydratase WcfK SWALL:Q9XDJ2
                     (EMBL:AF048749) (339 aa) fasta scores: E(): 5.1e-135, 100%
                     id in 339 aa, and to previously sequenced Bacteroides
                     fragilis putative dehydratase WcgW SWALL:Q9F749
                     (EMBL:AF285774) (335 aa) fasta scores: E(): 1.7e-112,
                     84.07% id in 339 aa, and to Pseudomonas aeruginosa protein
                     similar to NAD dependent epimerase/dehydratase family
                     SWALL:Q8KHX6 (EMBL:AF498401) (317 aa) fasta scores: E():
                     7.1e-10, 28.57% id in 343 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="putative epimerase/dehydratase"
                     /protein_id="CAH06763.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0982"
                     /db_xref="EnsemblGenomes-Tr:CAH06763"
                     /db_xref="GOA:Q5LGH6"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q5LGH6"
                     /translation="MNILISGIHGFVGSNFIRALKDKHTLYGLDIVSPAKEGVVTTFSW
                     QDFEPTSFPFQTLPQFDAIIHLAGKAHDTKKQSAAQSYFDINTGLTQKIFDFFLESSAK
                     KFIFFSSVKAAADSVVGDVLTEDVIPTPVGPYGESKIKAEEYIKNHFMFPTSSISEDRS
                     LRLEKEKGRIPKNKQVYILRPCMIHGPGNKGNLNLLYNVVKKGIPWPLGDFDNRRSFTS
                     IDNLCYVIEGLLNQDVPTGIYHMGDDEALSTNELIGIMCEAMGKKPHIWKMNKRVMEGC
                     AGLGTLMHLPLNTERLRKLTENYVVSNAKIKAALGIDKLPVTAKEGLMKTIRSFEETK"
     gene            14433..>15347
                     /gene="wcfL"
                     /locus_tag="BF9343_0983"
     CDS             14433..>15347
                     /gene="wcfL"
                     /locus_tag="BF9343_0983"
                     /old_locus_tag="BF1026"
                     /note="Similar to Bacteroides fragilis putative
                     UDP-GlcNac:undecaprenylphosphate GlcNac-1-phosphate
                     transferase WcfL SWALL:Q9XDJ1 (EMBL:AF048749) (318 aa)
                     fasta scores: E(): 3.8e-130, 100% id in 318 aa, and to
                     Bacteroides fragilis putative undpp-quinac-p-transferase
                     wcgX SWALL:Q9F748 (EMBL:AF285774) (316 aa) fasta scores:
                     E(): 4.7e-111, 85.62% id in 313 aa, and to Bacteroides
                     thetaiotaomicron putative udp-glcnac:undecaprenylphosphate
                     glcnac-1-phosphate transferase BT0396 SWALL:AAO75503
                     (EMBL:AE016927) (329 aa) fasta scores: E(): 7.5e-68, 55.34%
                     id in 318 aa"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P0AC78|9.B.146.1.7"
                     /protein_id="CAH06764.1"
                     /db_xref="EnsemblGenomes-Gn:BF9343_0983"
                     /db_xref="EnsemblGenomes-Tr:CAH06764"
                     /db_xref="GOA:Q5LGH5"
                     /db_xref="InterPro:IPR000715"
                     /db_xref="UniProtKB/TrEMBL:Q5LGH5"
                     /translation="MYYLIILVLLFLAELFYFRIADKCNIIDKPNERSSHTRITLRGGG
                     IIFYFGALAYFLTNHFEYPWFMLALSLITFISFIDDIRSTSQGLRLVFHFTAMALMFYQ
                     WGLFSLPWWTILVALIICTGIINAYNFMDGINGITGGYSLIILIALAYINRIYVPFVEP
                     DLIYTMLCAVLVFNFFNFRKQARCFAGDVGSVSIAFVILFLIGSLIIKTENFGWLILLA
                     VYGVDSVLTIVHRLMLHENIGLPHRKHLYQIMANELRIPHVVVSLVYMIAQIIIIIGYL
                     YCRNYGYWYLLGCILLLSGIYIVFMHKYFHLHLLSKR"
     misc_feature    order(14442..14495,14553..14606,14616..14669,14703..14756,
                     14766..14825,14844..14912,14922..14975,14994..15062,
                     15075..15143,15210..15278,15288..15347)
                     /gene="wcfL"
                     /locus_tag="BF9343_0983"
                     /note="11 probable transmembrane helices predicted for
                     BF1026 by TMHMM2.0 at aa 4-21, 41-58, 62-79, 91-108,
                     112-131, 138-160, 164-181, 188-210, 215-237, 260-282 and
                     286-305"
     misc_feature    14619..15053
                     /gene="wcfL"
                     /locus_tag="BF9343_0983"
                     /note="Pfam match to entry PF00953 Glycos_transf_4,
                     Glycosyl transferase, score 8.6, E-value 2.2e-08"
ORIGIN
        1 atgaaaggta ttgttttagc aggtgggtcg gggacacggt tatatcctat aactaaagga
       61 gtgagtaagc agttgcttcc tatctttgat aaacctatga tttattatcc tatttctgta
      121 ctaatgttgg caggtatacg ggaaattctc attatttcta ctccagatga cttgccggga
      181 tttcaacgtt tattgggtga cggatctgat tttggggtga ggtttgagta tgcagagcaa
      241 ccttcacctg atggtttggc acaagctttt atcataggag aaaaatttat aggggatgat
      301 tctgtctgtt tggttttagg tgataatatt ttttatggcc aaggatttac gcgaatgtta
      361 aatgaggctg ttcgtattgc agaatcagaa agtaaagcaa ccgtttttgg ctattgggta
      421 agtgatcccg aacgctacgg tgtagcggag tttgatgaga acgggaatgt tttcagcata
      481 gaggaaaaac ctcagaagcc aaaatctaat tatgccgttg taggattata tttttatcct
      541 aataaggtgg ttgaagtcgc taagagtatt agaccctctt ctcgtggtga gttagaaata
      601 acgactgtca atcagaactt tttatcagat aaggagttga gggttcaatt attaggtcgg
      661 ggatttgctt ggcttgatac aggtacacat gattctttat ccgaagcaag tacttttatt
      721 gaagttattg agaagcgtca aggcttaaaa gttgcgtgtt tagaggggat tgctttaaga
      781 aaaggctgga tttctccgga aaagatgaaa gcattggcac agccaatgct taagaatcaa
      841 tatggacaat atctgttgaa ggttatagat gaattgtatg taaaataaaa ctactttctt
      901 ccaatgaata taataaaaac agctattgaa ggacttgtga tccttgagcc acaactcttc
      961 aaagatgatc gtgggtattt ctttgaatct ttcaatcaga gagaattcga agaaaaagtc
     1021 tgtaaaacta cttttgtaca ggataatgaa tctaagtcaa gctatggcgt tattcgtggt
     1081 ttacattttc agaaaccccc ttttgcccag agcaagttag tgcgggtgat taagggagct
     1141 gttcttgatg tagctgttga tattcgtaag ggttcaccta catttggaaa acatgtatct
     1201 gtagagctta cagaagataa ccaccgtcag ttctttattc cacgtggctt tgcgcatggt
     1261 tttagtgtgc tgagcgaaga agtaattttt cagtataagt gtgataactt ttatcatccg
     1321 gaagcagaag gagctattgc ttggaatgat ccggatttag gaatcgaatg gagagttcct
     1381 tgtaaaagta taattctttc taagaaggat agggtacatc cgttattgaa atacattata
     1441 ttgtttaaat aatatttttg gagtatatct atgaaaaagt tagtttatga tgtacgaaaa
     1501 gatataattc catggaattc tcgtattact agaattttat tttttttgaa taaaataccg
     1561 tatttgagac ttttttcgaa acctttgttg aggaaacagt ttaatttatc aaatacagtt
     1621 caatttaatt cgggattttt ttgtcatgct ccgaaattga agtgtggaaa ttatgtagga
     1681 ttatctgata cttttatttt ggcttatgca gacgtcgtta ttggtaacaa cgtatctttc
     1741 tcttttagga atatgttaat tacgtcaaca catgatgtta atgattttaa taaaataata
     1801 gcttcctcaa ttgttatagg caataatgtt tggataacat caaatgtaat aatactggct
     1861 ggtgttaaaa taggagataa tacaataata ggagcaggga gtgttgttac acatgatatt
     1921 cccgcaaatg tatttgcggc aggtaatcca tgtcgtgtaa taaaaagtat aagatttaat
     1981 aagaatgaat aattctagaa ctgctaaagg attaaaaaat gcacaagtag ctttattgtt
     2041 ctattttata aatcttatct tgagttttct ttctcgtaag gcatttatag aacatttggg
     2101 agcagaggta cttggtttaa atacaacatt aactaatata cttgtctatt taaatttagc
     2161 agaacttggc attggctatg caataagtta tgctttatat aagcctttgt atgagggaga
     2221 taaacaagct gttaacgaaa ttatttctat tcaggggtgg ctgtataaaa gaattgcgat
     2281 aattgtgatt ataatgtctg gagtcatatt attgtttttt cctttatttt ttgctaagat
     2341 agaaattcct atatggtatg tatatgcgac atttttagtt ttattatcta gttctatttt
     2401 tagttatttt tttaattaca agcagtttgt acttactgct gatcaaaaag aatataagtt
     2461 gatcactaat gtgcagggat ttaaggtggt aaaaactatt ttacagattg ttgtaatagt
     2521 atatttttgt aatggatatg tttggtggct gctacttgaa ttgttaatgg gtgttattac
     2581 ggtattcgta ttgaattcta ttgtaagaaa agaatatcct tggcttcaaa cttcacctaa
     2641 gataggaaaa gatgttaaag ataagtatcc ctatataata aaaaaaacga aacaactttt
     2701 ttttcataaa atagcaaatg ttgttttgaa tcaaacaagt cctattatta tttattcata
     2761 tactaatttg acaatggtag cagtatatgg aaattatatg ctcataatat ctggaatttc
     2821 tttattgata aattcagttt tcagtagtat tggtgctggt attggtaatt tagttgcaga
     2881 aggaaatcaa gcaaagatta tacaagtttt taatgagttg ctttcttcaa gaatttggat
     2941 tgtttcaatt ttgtgttttg gtgtttatca aatgtctaga ccgtttattg tactttgggt
     3001 aggtgatcgt ttcgtgttag atgattttta tttattgttg atgcttttaa ttgcctttat
     3061 ttctttgact cgtttagttg atctatttat tgcagcttat ggactctatc aagatgtatg
     3121 ggctgctata ttggaagcct tcttgaattt aggactttca attttatttg gttattactg
     3181 gggactttct gggattctag ggggagtaat agttagtttg gtaataattg ctttattatg
     3241 gaaaccattt tttttattta aatatgggtt taataaaaat tgcttgaatt tttattttgt
     3301 ttacatgaaa tgcgttgctt ttgctttgat aacattttat ttttctatca gagttattga
     3361 ttatattggg attggtatgt gtactgatta tagcagttgg atactaattt caatgttgaa
     3421 tatttttgtt tatactataa ttagtttccc tattttcttc tttttttctg atggtactaa
     3481 tagatttatt aagcgagtta taaatatagt ctttaattga tatatgttat atgtaatttt
     3541 acgtggacga ttaggtaata atctttttca gatagcaact gccgcttcgt tgactcagaa
     3601 ttttatattt tgtacagtaa ataaggacca agagagacag gtccttttgt ataaggattc
     3661 tttttttaaa aatataaaag ttatgaaggg ggttcctgat ggcataccat attacaaaga
     3721 accattccat gaatttagca gaattcctta tgaagaagga aaggatctca ttattgatgg
     3781 atatttccaa tcagaaaagt actttaaaag aagtgtcgta ttagatcttt atagaataac
     3841 tgatgagcta aggaagaaaa tatggaatat ttgtggaaat attttagaaa agggagaaac
     3901 tgtgagtatt catgttagaa gaggtgatta cttgaagctg ccacatgcat taccattttg
     3961 tggaaagtca tactataaga atgctattca atatattggt gaggataaaa tattcattat
     4021 ttgtagtgat gatatcgatt ggtgtaaaaa aaactttata ggaaaaagat attacttcat
     4081 agagaacact actcctttac tagatttata tatccaatcc ttgtgcactc acaatattat
     4141 aagtaatagc tcttttagtt ggtggggagc atggcttaat gaaaatagta ataaaattgt
     4201 tattgcacct caaatgtggt ttggcatttc tgtgaagttg ggtgttagtg atttattgcc
     4261 tgtcagttgg gttcgacttc ctaataatta tactttagga agatattgtt ttgctctata
     4321 taaagtagtt gaggactatt tattaaatat tctgcgatta atatggaaaa gaaagaagaa
     4381 tatgtgaaaa agaaaatgac tcttattgtg aatcatccat ggaatgatgt ttttgagggt
     4441 aaagatgttt ttttagttcc atgttacatt ggtaaaattt atcattatga tgttaagatt
     4501 gtttttcctt cgaattattt gtatgaagca aaaacaataa gagatgttga acttgttcct
     4561 gtatcatata ttaaaaaact tcgtcctttt tcttttgtgt ttggttttaa actaatgaga
     4621 tatttgtttt gtaacgctag aaaaatagat ttatttatgc gctttcatgt tacaattaca
     4681 actgctatta tgattattat ttataaaatg ctaaatagaa atggaatagc atatataaaa
     4741 ctagatagta atggggttat gaattttgaa tataaaaata atttaaaaag tctattcagg
     4801 aaattattgt ataggaggat gtttgaattg gtggattttg tatcatatga aacaaaaatg
     4861 ggactcgaaa atattaccca gcaaacaata ggaattgata tcagttcaaa gctattctat
     4921 atgcctaatg gctttgatga agatatgata aaacacttgg atattaatgt gaaagaatac
     4981 tctgataaag agaatgtaat gattacggtt gggcgtttag gaacaaatca aaaaaacaca
     5041 gaattatttt taaaggctgt ggaaaacatc gacttgaaag attgggtaat ttatttgatt
     5101 ggagatattg atcctcagaa tattactttt ttagagtttg tttcaaactt cttttctaat
     5161 catcctgaga aaaaaaagtc tgtaattttt acaggagcaa taagtgataa aaggcattta
     5221 tgggaatatt acaataaatc taaagtgttt gtattgactt ctcggtgtga aagctatggt
     5281 ttagtattga atgaagcaaa acgatttcga aactttatag tttctactaa tgtaggagct
     5341 tttgaagact tagttgagtc tggcaaatat ggatgtgaga ttcctcaaga taatacggac
     5401 tatttggctt gtattttaga aaaaataatt ctcggtcagt tagatataga tgtatataat
     5461 gatttttctc ctgaatctct ctcctattat taccaagtaa aaagaatgaa attaaataat
     5521 tagttgttat tatcattgga atgatttatt atctatttag gccttgttta tatgtttgta
     5581 aaatgttttt aaattatttc gtttgtttta cttctaaaat ttgtacagag aatcgttata
     5641 actattttaa aagaataaag ccttttcttt tttctcgaat agttcgtaca tggtttggac
     5701 atgtaggtga taaaatatct attgtccctc ctttttatat acgaggggga aagtatattc
     5761 aattaggtac taattttagg gcattaagcg ggcttcgttt ggaagcaatt gatttttata
     5821 ataatagttc ttatcatcca agtatagtaa ttggggataa tgttgttttt aataatagtt
     5881 gtcatattgg agctactaat agaattatta ttggtaacga tgtagtggtg gcaagtcgag
     5941 ttttcataac agatcatttt catggtaata caacgtacaa tgatttacaa attccagtaa
     6001 gaaacagact actatattct aaaggtcctg ttgttatagg taataatgta tggattggag
     6061 aaggagcttc aattttgcca aatgttacaa ttggagataa ttcgatagtg gctgcacatg
     6121 ctgttgttac aaaaaatatt cctgccaatt caattgcagt tgggtgtcct gcaagaatta
     6181 ttcgaaccat aaactaagtg aatttatttg tcctactttt tgtttttgta tttggtatta
     6241 ttggatctta ttcctctaaa ttttctgaga agaatctgtt ttggcttttt gtaatagttt
     6301 tggctattat aataggaggt cgtagtatat ctgtacctga tacggaccaa tatttagaat
     6361 tttatcagct aacactttcc tcttctatct tagatattcc tttatactct tatgaaatag
     6421 gatttcaatt attgactaag atattaaagc tgataacgaa tggttcttct ttcttttatt
     6481 ttggaataat tgttcttata aattcatatt ttctttttaa atctttcagc tgttttacag
     6541 atcagtctta cccctcaaaa aaatcttctg gtactctaat taatcaaatt aaattacaag
     6601 agttccttct gttatacttt tcatattggg gattgtatta tacaggtatc gttttaaggg
     6661 caggaattgc tatgtctatt ctaatttatc tatcaacttt attgtgttcc ccttatatct
     6721 ctttaaaaaa atggtcagcg atatttttat tagcaattat atcttgttct ttccatatta
     6781 ctgccctttt aggaattatt gctcttatta ttttttatat atcaaagaaa atgacaatga
     6841 gatcgtattt gttacttttc ttgttgatct gtataatttt atttggaaag gtaagctttt
     6901 ggattgtaga tatgttagat aggaatatgc ccatgatatt ttcattgata gaggatactg
     6961 attttgctaa attgcaagca tacagtaata ttgatgcttc tattaaaatt tcatttcgtt
     7021 ttttattttg tttgcttata ggcttgtttt ttataatatg taaaaggatg ccgctatatt
     7081 attataaata tttgaacgtt tatattgttg gtttattttt gggggcactt tttagtgcta
     7141 ttgaagcgtt ctctagaata atggactttt ttgttatata ttcttttatc cttatttcaa
     7201 tgcgtttgtc tactataaat agttttaaaa tacgctttag tataatgttt tctattgtat
     7261 taatacaatt attgtttgtc tatagaatta ttattggttt atgaataatc atattaagag
     7321 gaaagctgta tcagttgtta tagttacttt taattcggaa aatttaataa tggattgtct
     7381 ggattcaatt tttaagtata atgatatttc tgatgatttg gaagtagtgc tagttgataa
     7441 ttgtagtaaa aattatttgt ctatgtttgg ctctattgaa gaaaagtatg gcaataaagt
     7501 tgttcttata aataataaag ttaatggtgg ttatgggcaa ggcaataatt taggggtaga
     7561 ggttgcaaaa gcaccaataa ttctaataat gaatcctgat gttagattgg ttaagcctat
     7621 ttttaaaaga attttgtctt tatttgaaag gaggaatatt gcaatagctg gtatgcaaca
     7681 atatgaatca ttgttgaaaa gaagccaatc atttttaatg ttgagagagg atttgtgtag
     7741 cttattttta tatgcggtat acactaagat aaataagttt aatgaaaaat atttttgtat
     7801 atctggtgct tgttttgctg ttagaaaatc tgtttttact aaagtaggaa tgtttgatga
     7861 acaaatgttt ctttatggtg aggagcgaat gttacattat aaaattttac gtttaggaaa
     7921 ttatcatatt gtatatgata gtacaattgg atatttacat cctaaggaga atcgggaatt
     7981 ttcttctaaa aatttcttgc ttggttatca ttcatttata tatacatgtg ataaattagg
     8041 attagacctg catagatctc gtaataagat gttaaacatg tatagattcc ttgaatttta
     8101 ttcatgggct agaggggata agttaaaggt taagtattat aaagaaataa ttaagttgat
     8161 aaaaaataat atatagaaat tgaaatggaa gaattaaaga ttgccgtaat aggtcttggt
     8221 tatgttgggc tacctttggc tcgattgttt tcgacaaaat atgaatgtat tggttttgat
     8281 ctgaaccagt ctcgtgttga tgctttaaat tccggtcatg atatgacttt agaggtttct
     8341 gatgacttac ttcggaaagc gttagaaaat ggtttcaaat gtaccagtaa tattgacgaa
     8401 ataagtaatt gtaactttta tgttgtagct gtaccaaccc ctgtggattt gaataatcgc
     8461 cccgatctta cacctttgat tggtgcgagt acaacagtcg gaaaagttat ttcaaaaggg
     8521 gatattgttg tgtatgaatc tactgtatat ccgggagtaa cagaggaaga atgtcttccg
     8581 gtagtcgaag aggtgtctgg gttaacatac aatgtagatt tttatgcagg ttattcacca
     8641 gaacgtataa acccgggtga taaagagcat actgttgaaa agattaagaa agtaacttcc
     8701 ggttcgactc ctgagattgc tgacattgtt gattctgttt ataattcagt gttggttaac
     8761 ggtactcata aagccccttc tatcaaagtg gctgaagctt ccaaaataat agagaactcc
     8821 cagcgcgatg tgaatattgc cttcatgaat gaactctcaa agatcttcaa tgcaatgggc
     8881 attgatacca atgatgttat tgaggctgca tcttccaaat ggaattttat caagttgaaa
     8941 cctggcttgg tcggtggtca ctgtattagt gttgatcctt attatcttat tcagaaggcc
     9001 caggtttatg gggtactccc acgaatcatg tctgcagcaa ggcgcttgaa tgatggtatg
     9061 ggagactatg tcgctaatca ggtgattaga ttaatgaata aaaaaggtat tcttgtcaaa
     9121 gattcaaaga ttctgcttct gggttttact tttaaagaag attgccctga tattcgaaat
     9181 accaaggtga tagacattta ttctacctta catgagtata cttctgacat taccgtttat
     9241 gatgcttggg ctaattcggc taaagtggca catgaatatg gtatatcgat cctgactgct
     9301 ggtcttgata atttggttgg acaatttgat gcggtggtgt tgtgtgttgg acataaagag
     9361 ttccggcata tgaatattcg cggctttctc cgttctgata tgggtgttgt ttatgatgtt
     9421 aaagctgtat tgagtaaaga tataatagat ggcagattat aattcttcta tttgttgtat
     9481 ttttaatata gggactcact atcgcaatcc tatatattca aaaatgtctt cggagcttcc
     9541 ctgcgatttt tattttggcg atcgtttatt gacaccaata aagaaaatgg attataccca
     9601 attgaaccat tttcgctcag aattgcataa caaatattta ttttctcagt tttattggca
     9661 atctaaatct gtccggttag tctttaaacc ctatacttat tatgtattgg atggagaacc
     9721 ttattgtttg tcttcatggg ttatcctttt ctgggcaaaa cttttaaata agagaacagt
     9781 agcttggact catggttggt atggcagaga aagtattgta aagaaggtta taaaaaagtt
     9841 gttttattct ttgttttctg agttgatggt ttatggcgaa tatgctattt ccctgatgtc
     9901 aaaagaaggc tttgataaat caaagatggt ttgtattgca aactctttgg attatgataa
     9961 tcagttgaaa attagactca atttatcgcc ttcttctatt tattctactc atttttccaa
    10021 ctcctatcct gtattattct atatcgggcg tgtgcaaaaa tcgaagaagt tggaatatat
    10081 aatccaagct atggatatct tgaaacagaa agggtttccg gtaaatcttg ttgttgtcgg
    10141 taaagatgtg gatggggttc atcttgattg tgaaatagct aaatataatc ttggctctca
    10201 tgtctggtta tatggacctt gttatgacga gatgcgcata ggagagatgt tctataatgc
    10261 ggatgtctgt gtgtctccag ggaatgttgg cttgactgct atccattctc tgacttatgg
    10321 ttgtcctgtt ataacccata ataattttcc ttttcagggt cctgaatttg agtctataat
    10381 tcaggggaaa accggtgatt tttttcagga aaatgatgta aatagcctgg ctgatactat
    10441 tcagaaatgg ttaagtcaga atttgcatag tcgagaggct attcggcagt ttgcctatca
    10501 gacaattgat accaaatgga acttgtatta ccagatgaat attctcaaac aagtttttct
    10561 taaacaagct aaggatgaat gactttcgga gtttaataag gaatagtgtt ttggatattt
    10621 tagggatatt ttcccgtcct caaaatggta ttcatatatt gaatggacat atgatatgtc
    10681 gtggagtggc taatgatcaa gcaaaatatt atttttctta tcaattaaaa gaactttccc
    10741 gacatgtacg tttcataagg gtggaggagg ccacttctct aattctcaat catgaaagtg
    10801 tcgatgaacc tttggttgcc tttacatttg acgatggttt tatggaatgt cattcaatga
    10861 tagcacctgt tttggaacag tttggggtga atgcggcttt ttttatcaat cccaattttg
    10921 cgaatgggga tgatgtgtat attcaaaatt ttacaaataa catagttctc actcccggta
    10981 aaactccaat gcggtggaaa gagataaggg atttgcatga gaggggacat attattggtg
    11041 cacatacaat ggatcattat atgattaatg atagtaattg ggtggaatta gacaagcaaa
    11101 taggttgttg taaatcggta atagaacagg aactctctac ttcttgtgaa tactttgcct
    11161 ttccatatgg acgcttggaa cacgctaatc aatcttcgat tgatattgca tgtaagtatt
    11221 acaaatatgt gttttctcaa tcggactata aacattactt ttcttttggc ggtcgcgtaa
    11281 ttaacagacg gcattttgag cctttttggc ccgtgaaaca tgtttcttat tttttgagtt
    11341 gccataaaaa ataggggact ttaattagtc ttttcgatct tgttctcttc tatttgatca
    11401 ctacgatagt gaaaactctc tttcaaataa atgttgttgc taactctggt tccaccggcc
    11461 atattgcaga ggagttaggg cgtttggtta ttgcttctgg ctggaaaagt tatattgctt
    11521 acggtcgttg ggcctgtccc agccaatcta tgttgattcg ggttggaact agatttgatc
    11581 tctttgtcca tggcttgaaa tccatgtttt ttgacaggca tggttttggt tcacggagag
    11641 ctaccttgca cttaatctca aaaatagaga aaataaaacc ggacataatc catttgcata
    11701 atcttcatgg ctattattta aactgtgagg ttttatttga ctatctatct acagctaaaa
    11761 tacctgttgt ttggactttg catgattgtt ggagtttcac gggacattgt gtccattttc
    11821 agaatatcgg gtgtgagaag tggaagacag gttgttttgc atgtcccaat atacgagatt
    11881 atcccaaagc tttaggttgt gataactctc gtatgaactt tatagaaaag aagagattgt
    11941 ttacttcggt tgaacgtatg atgattgtac ctgtttgcaa ttggctaagt gatatgttga
    12001 gtaagtcata tctttctcaa ataaaacggc agactattgt taacgggatt gatttggaaa
    12061 tgtttactcc caaaggtaat cgtgatgtga taaaaagtaa tttaggggta gggacacgat
    12121 atatgatttt agcagtcgct acggtttggg ggattacgaa ggggtttgat gatcttatat
    12181 acctcaactc tttattacca gataagagtg taattgtagt ggtgggggta accacgaaac
    12241 agataaaaaa attacctggt aatatgattg gtatagagag aacggaaaat actagtcaat
    12301 tggttgaaat atattctgct gcagatattt ttataaaccc gacatatcaa gatacattac
    12361 ctacagtcaa tattgaagcg cttgcttgtg gtactcctgt tataacttat gataccggag
    12421 gcagtgctga tattgtagat tctgatacgg gaatggtttt aaaacgtggg gatattcata
    12481 cgttattaga aaagatttta gaaataagag aaagaggtaa agagtcttat ataataaaat
    12541 gtcgtcagag agcattgcaa ttttttgata agtcaaagca gttgagttac tacttgtctc
    12601 tttatgatca attactaaat aaagaaagat agtttttctt tcatagttat gaaaatatcc
    12661 cttgttactg tcacttttaa tagtgctaag acgctttgtg atacgattca ttctgtcctt
    12721 tcacagtctt atactaatat agaatatata atagtggatg gtttgtctaa tgatgaaacc
    12781 gttacactta ttaaagaata tgagcctctg tttcaaggtc gtttgaaatg gataagtgag
    12841 aaagacaagg gactctatga tgctatgaat aaaggaattc gaatgtctac cggggatatt
    12901 gtcgggatta ttaattcgga tgatttttat catagaggag acgttttaga aaaagttgct
    12961 gagtcgtttg aagctggtga gacagaggct atttatggag atgtacgttt tgtaaatcct
    13021 gataatttgg ataggacagt tcgctattat tcctctaaaa ggtttgtccc atccttgttt
    13081 cgatttggat ttatgcctgc tcatccaact ttttttactt atcgaaaata ttttgatcag
    13141 tttggctatt ataaaacaaa ttataaaata gctgctgatt atgagttgct tgttcgtttt
    13201 ttatatgtac accggttaaa gagtaaatat ttacctttgg attttatgaa aatgaggaca
    13261 ggaggtgcga gtacggcttc tattaaaagt aatatcctat tgaataaaga gatagtcaga
    13321 gcctgtaagg agaatggaat atggacttgt tatcctttgc ttctattaaa atatttagta
    13381 aaagtatttg aactgatttt tataaaaaaa tgaatatact tatttctgga attcatggtt
    13441 ttgtaggctc taattttatt agggctttga aagataaaca tactttgtat gggcttgata
    13501 ttgtttctcc tgctaaagag ggagtcgtaa ctactttttc ttggcaagac ttcgaaccca
    13561 catcttttcc ttttcaaact cttccccaat tcgatgccat tattcatctt gccggaaagg
    13621 cccatgatac gaaaaaacaa tcagccgctc agtcctattt tgacatcaat accggtctga
    13681 ctcaaaagat attcgacttc tttttggagt cttctgccaa gaaattcatt ttctttagtt
    13741 cggtgaaagc tgctgccgat agtgtagtag gagacgtgct tactgaagac gtgattccta
    13801 ctccggttgg tccttatggg gagagtaaga ttaaggcgga agaatatata aaaaatcatt
    13861 ttatgtttcc aacttcttct attagtgagg atcggtcttt gcggttggaa aaagagaagg
    13921 ggaggatacc caagaataaa caggtgtata ttcttcgtcc ctgcatgatt cacggaccgg
    13981 gaaataaagg gaatctgaat ttattatata atgtagtgaa aaaaggaatc ccttggcctc
    14041 ttggcgattt tgataatcgc cgttcgttta cttcaatcga taacctttgt tatgtgattg
    14101 aggggctttt gaatcaggat gtgcctacgg gcatctacca tatgggagat gatgaagctc
    14161 tttcaacgaa tgaactgatt ggcatcatgt gtgaagcaat gggaaaaaag ccgcatatct
    14221 ggaaaatgaa caaaagggtt atggaaggat gtgccggcct gggtactttg atgcatttac
    14281 ctttgaatac ggaaagactt cgtaaactga cggaaaatta tgtggtaagc aacgctaaga
    14341 tcaaggccgc tttgggcatt gataaattac ctgtaacggc taaagaagga ttgatgaaga
    14401 ccattcgttc atttgaagaa actaaataac ttatgtacta tctaataatc ttagttctgc
    14461 tattcctggc agaacttttt tatttccgta ttgcggataa gtgtaacatt atcgataagc
    14521 ctaacgaacg tagttcacat acccggatta cactgcgtgg tggagggatc atcttttatt
    14581 ttggggcgtt ggcttatttt ctgacaaacc actttgaata tccatggttt atgctggctt
    14641 tgagtctgat aacctttatc agttttatag atgacatccg ttctacttcg caaggacttc
    14701 gtctggtctt tcattttacg gcaatggctt tgatgtttta tcaatggggg ctgtttagct
    14761 tgccttggtg gacgatcctt gttgccctga tcatttgtac tgggattatc aatgcttaca
    14821 actttatgga tggcattaat ggcataacag gcggatattc attgatcatt ctgatagcat
    14881 tggcctacat aaataggata tatgtcccat ttgttgaacc ggaccttatt tatactatgc
    14941 tttgcgcagt attggtcttt aattttttta atttccgcaa acaagcgaga tgttttgccg
    15001 gtgatgtcgg ttcggtcagt atagcttttg taatcctgtt cctgatcgga agtttaatta
    15061 tcaaaacaga gaattttggc tggcttatat tgcttgctgt atatggagta gatagtgtgt
    15121 tgacgatcgt tcatcgattg atgcttcacg aaaatattgg tttgcctcac cggaaacatt
    15181 tatatcagat aatggctaat gaactgagaa taccgcacgt agtagtatcg ttggtgtata
    15241 tgattgcgca aattataatt atcatcggat atttatattg ccggaattat ggttattggt
    15301 atttattggg ctgtatcctc ttgctgagtg gaatatatat tgttttt
//
