LOCUS       MN148383               25336 bp    DNA     linear   BCT 18-JAN-2020
DEFINITION  Acinetobacter baumannii strain BAL_309 KL74 capsule biosynthesis
            gene cluster, complete sequence.
ACCESSION   MN148383
VERSION     MN148383.1
KEYWORDS    .
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Kenyon,J.J., Hall,R.M., Holt,K.E. and Baker,S.
  TITLE     Sequence of the Acinetobacter baumannii KL55 capsule biosynthesis
            gene cluster
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25336)
  AUTHORS   Kenyon,J.J., Hall,R.M., Holt,K.E. and Baker,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2019) School of Biomedical Sciences, Queensland
            University of Technology, 300 Herston Rd, Herston, QLD 4006,
            Australia
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="BAL_309"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /country="Viet Nam"
     misc_feature    1..25336
                     /note="KL74 capsule biosynthesis gene cluster"
     gene            complement(1..2184)
                     /gene="wzc"
     CDS             complement(1..2184)
                     /gene="wzc"
                     /note="protein tyrosine kinase; involved in capsule
                     export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzc"
                     /protein_id="QHE90341.1"
                     /translation="MNQNTNTEDTIDLKELFFSLIAQWKLIALCIILSLVCALLYLRV
                     TPDTYSVDALVQVEDSKGASAALLGDLSQMIEQKSPAQAEIEILKSRLVLGSVIKDLH
                     LNIQISSTENTLTHQLLSNTEYKTEYTKKSVLFQDDFKSFEVREFEVPNYYLDKNLLL
                     NFDKQSLTLTDPETEEVILTVPLNQANHVTGPHGLWKVAIFTKDQLDATYNITNLSLP
                     AAVNALSVNYSVAERGKLTGVLGLNYQGQDKEHITKVLNAILATYSAQNIERRSAESA
                     QTLKFLDEQLPDLKKQLDDAERQFNKFRQQYNTVDVTKESELYLTQSITLETKKAELE
                     QKQAEMAAKYTAEHPAMREINGQLAAINKQIGELNSTLKQLPDVQRQYLQLYREVEVK
                     TQLYTALLNSYQQLRIAKAGEIGNVRIVDTAVEPVEPIKPRKLLVLILSVFVGGFIGT
                     LIALLRNMLRTGIKDSGQIENELDLPVYATVPRSPIQESRIKILKKKKSIPILAVKNS
                     DDIAIESLRSIRTAIHFALANAKNNIIMIAGPSPEVGKSFISTNLATIFAQGDKRVLL
                     IDADMRRGYMHKYFDVDVKPGLSELLSGQADLSQVLHKTQVTNLDVITRGKSPTNPSE
                     ILSSNQFKELLEQLQSQYDHIIIDTPPVLAVTDGIIISQYTGVNLIVARYAKSQMKEL
                     ELTVNRFEQAGVKVNGFILNDIQRASAGYGYGYNYAYAYKAQKED"
     gene            complement(2203..2631)
                     /gene="wzb"
     CDS             complement(2203..2631)
                     /gene="wzb"
                     /note="low molecular weight protein tyrosine phosphatase;
                     involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzb"
                     /protein_id="QHE90342.1"
                     /translation="MQINNILVVCVGNICRSPMAEYFLKQQYPQLNIESAGISGLVGH
                     QADNKAQLCMQRLGIDMQPHIARKLNASHIKKADLILVMSNNQLKHIEQTWPFAKGKT
                     YRLGHWQNKNVPDPYQHDQTVFDETCQLIQQCIADWKPYI"
     gene            complement(2636..3736)
                     /gene="wza"
     CDS             complement(2636..3736)
                     /gene="wza"
                     /note="outer membrane protein; involved in capsule export"
                     /codon_start=1
                     /transl_table=11
                     /product="Wza"
                     /protein_id="QHE90343.1"
                     /translation="MKYCQFFSVLALSLSAASCAVTSGLQTYDIPSEGVYKTDLGTTV
                     NVVKISQETLPAIQPAQIDYQRDYASLFKNQQSIYRLSPGDVLSIQLWAYPEITPPVN
                     NISNEQSIQANGYPIDQSGYIQFPLVGRYKAAGKTLAQVNRELRSQLARFLKNPDVVV
                     RVVSYEGQRFSVQGSVTKGGQFYLSDQPVSIYTALGMAGGVTTTGDNTYIQLIRNGRT
                     YNLNTIDLEKAGYSLHKLLIQPNDTIYVSTRENQKIYVMGEAGKSQALPMRDQGMTLS
                     DALGESLGINPTSGSASKIYVVRSNPNDRTTEIYHLNLMSIGDFGLANQFRLRSNDIV
                     YVDATGLTRWQRVINQIIPFSNALYNIDRLGQ"
     gene            4092..5366
                     /gene="gna"
     CDS             4092..5366
                     /gene="gna"
                     /note="UDP-N-acetyl-galactosamine dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gna"
                     /protein_id="QHE90344.1"
                     /translation="MQIAKLKIAIIGLGYVGLPLAVEFGKKVPVVGFDIYQKRIDELK
                     NGQDHTLEVSPEELKQAVHLNYTAHLDDLQDSNFFIVTVPTPIDDFKQPDLTPLIKAS
                     TSIGRVLKKGDVVVYESTVYPGATEEVCIPVLEKVSGLKFNQDFFAGYSPERINPGDK
                     QHRVTNILKITSGSTPEVADYIDEVYNLIIEAGTHKAPSIKVAEAAKVIENTQRDVNI
                     ALINELALIFNKLDIDTEDVLKAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSIG
                     LHPEIILAARRLNDRMGEHVATQLIKEMVKQRIQVVGARILVMGLSFKENCPDIRNTK
                     IVDFINALKEYDLDLDIYDPWVNDTEVQHEYGLAPIKELQQGLYDAIVIAVAHNQFKS
                     MSVEEFHTLGKEKYVLYDLKYVLDKADSNLRL"
     gene            5396..6259
                     /gene="gtr110"
     CDS             5396..6259
                     /gene="gtr110"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr110"
                     /protein_id="QHE90345.1"
                     /translation="MNNNKIALVVIVYGKALEDALTIQSLLGFERKLDHLLIVNNGPT
                     VIDENSAVLSALAQKHHHVVLENQVQNKPLSWIYNDFIQQYNADYYVLFDDDTEINPE
                     YQRKIFIMQGVDIELPKIISMNDKAQYYPLVDGVIEQKDGIISNAKEIFSIGSGLVIS
                     KDIKQYFIENKIELFDSHFALYGVDFSFFRKINHIAKQKNIIFSISSNTYIKHSLSRT
                     EKETNAWRDKERLYDLVLTLKYYYSYAELRILKLFFKKILGGKIKDALLILSTTFNGA
                     HPRCMNKVLND"
     gene            6252..7205
                     /gene="gtr79"
     CDS             6252..7205
                     /gene="gtr79"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr79"
                     /protein_id="QHE90346.1"
                     /translation="MIEVSKVLEDRIDIALATYNGEKYITELLDSLDQQTYQNFIVHV
                     CDDGSKDRTIAICEAHSLFKKGKLEIHEKTGGNGASRNFIRTLSYCKNPYIALCDQDD
                     FWIPTKLEKMLVKTQHEEGSEKKPTLIFSDLQIVDEKLHILSPSYFAVSSKSNQCSTP
                     FDFLLSNHVPGCTMMFNQSLKQVFEPIPQEFRMHDWWIILIAAFWGRVIYLDESLIQY
                     RQHGNNTVGAVGMDKPTLIQKLRTVLLYKTILLKVDMVRKSFLPYIQQKEIQQEKLSL
                     EQKKFIDLLQRRLPLSKRLQIFSKTVTGEDRLLSFLVWCLL"
     gene            7202..8449
                     /gene="wzx"
     CDS             7202..8449
                     /gene="wzx"
                     /note="oligosaccharide-unit translocase"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzx"
                     /protein_id="QHE90347.1"
                     /translation="MSKAINKEVFYLYIIQIANMVIPLLSFSYMANILGLVGFGQVSF
                     YQTVSFLAAFFIDFGFNMSAAQKMSISLDDKSKMDELYSNVQSAKFFIFLIVSVLGGI
                     GVLLLPLSHIDATLLFIGILSAFSTILLSGWVFQGLGRNSVLAFFSVIGRVVSVGLIF
                     WLIHQKSDVLLAVIIQVAISFSIGLAAIIYFYRKNVVTFRFKSISIYKIKQLSEDSYH
                     NFTASLFTLGFTYLNPIIVKFCFGDAFLGLYAMADKLAVVIKQLFTPVTQAYYSRMCI
                     LSHEKKYQELIQNAKKVAIFFAGISIVAFAGNLLIGKYIYSFLFGPEYKITSLLSIMI
                     MTQFVVSMAMVLVNLIIIPTENSRILKKYYLIGLIFHFGYFYFFVKYLHIYGVASAIL
                     LTETILTLSFFMYVRKYFSKVLT"
     gene            8466..9629
                     /gene="ugd4"
     CDS             8466..9629
                     /gene="ugd4"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd4"
                     /protein_id="QHE90348.1"
                     /translation="MKITVVGTGYVGLSNAMLFSKQHEVTALDIDATKIDKLNQGISP
                     IHDDLIQEYLIDNSNFKATLDKNSAYVDAEVIIIATPTNYDEASNYFDTSSIESVLED
                     LNHLKSDAIIVVKSTIPVGFTERMKETFSALKVVFSPEFLREGKALYDNLYPSRIVVG
                     NTSEVGALVGQLFKNASLRPDVDVLQMDATEAEAVKLFSNTYLAMRVAYFNELDSYCA
                     SRGLNSKDIIQAVGLDPRIGAHYNNPSFGYGGYCLPKDTKQLLANYQDVPQNLIGAII
                     QSNTTRKDFIAEQILARKPKVVGVYRLVMKQGSDNFRQSAIQGVMKRLKAKGVEVIVF
                     EPSLNESTFFNSRVLTDFDSFKQESDVIIANRMVSELEDVIDKVYTRDLFGEN"
     gene            9648..10715
                     /gene="rmlB"
     CDS             9648..10715
                     /gene="rmlB"
                     /note="dTDP-D-glucose-4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlB"
                     /protein_id="QHE90349.1"
                     /translation="MKILITGGAGFIGSAVVRHIIQNTEDEVLNVDKLTYAGNLESLI
                     SVENNPRYQFSQTDICDRAALDKLFETFQPDAVMHLAAESHVDRSITGPYAFIETNVI
                     GTYQMLEASRAYWLSLSDEKKAAFRFHHISTDEVYGDLEGTTDLFTETTSYSPSSPYS
                     ASKASSDHLVRAWNRTYGLPVLVTNCSNNYGPFHFPEKLIPLMILNALQGKSLPVYGN
                     GQQIRDWLFVEDHARALYTVVTQGTVGETYNIGGHNEKANLDVVHAICDLLEELAPHK
                     PEGVAQYKDLITYVKDRPGHDVRYAIDATKIKEELNWVPKESFETGLRKTVEWYLNNK
                     EWVEHVQSGEYQSWLNKQYQG"
     gene            10718..11611
                     /gene="rmlD"
     CDS             10718..11611
                     /gene="rmlD"
                     /note="dTDP-6-deoxy-L-lyxo-4-hexulose reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlD"
                     /protein_id="QHE90350.1"
                     /translation="MKILLLGKNGQVGWELQRALAPLGDVIALDRHGLDSLSGDMTQP
                     QAIYDTILAVQPDVVVNASAYTAVDLAETEQELADIINHQTVKAAAEACQETNALLVH
                     YSTDYVFEGTGTTAFVETDVIAPLNIYGKTKALGEQAIVDSGCRYLIFRTSWVYASRA
                     KNFLKTMLSLAQQREELSIIDDQIGAPTSAELIADITAQAIPQTVADANKVGIYHLVA
                     SGETSWFGYANYAFTQARTLGQELAIQKVNPIPTSAYPTPATRPHNSRLDNQKIQRTF
                     GLTLPVWQEGVKRALMELLNK"
     gene            11608..12498
                     /gene="rmlA"
     CDS             11608..12498
                     /gene="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlA"
                     /protein_id="QHE90351.1"
                     /translation="MSLKRKGIILAGGSGTRLHPITKGVSKQLLPIYDKPMIYYPLSV
                     LMLAGIREVLIISTPEDLPNFEKLLGDGSQFGIELSYKVQPSPDGLAQAFLIGEEFIG
                     QDNVCLILGDNIYHGQHFSHQLEAASAREHGATVFGYHVTDPERFGVVEFDKTGKVLS
                     IEEKPAQPKSPYAVTGLYFYDNRVVEFAKQVKPSARGELEITDINNAYLQDGSLNVEL
                     LGRGFAWLDTGTHESLLEAGHFIYTIEKRQSFKVACLEEIGFHQGWISKEQLLDSAEA
                     LKKTEYGQYLKKVWEESNEG"
     gene            12488..13039
                     /gene="rmlC"
     CDS             12488..13039
                     /gene="rmlC"
                     /note="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlC"
                     /protein_id="QHE90352.1"
                     /translation="MKVETTKIEGLLILHPSVFGDDRGWFMESFNQQRFAQALEDLNL
                     PVPTFVQDNHSLSQKGVLRGLHYQNAPYAQGKLVRVVQGRVWDVAVDIRPDSKTYGEW
                     VGVELSAENKTMFWIPEGFAHGFISLEDNTQFLYKTTNYYNKESEGAIIWNDPTLAID
                     WPLAEVDEVLVSDKDQVAKEFKK"
     gene            13043..14128
                     /gene="gtr145"
     CDS             13043..14128
                     /gene="gtr145"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr145"
                     /protein_id="QHE90353.1"
                     /translation="MKKVFFLTNAVDLANSSDGLAKKIHAQTKAFQDCGYVTELAGCS
                     EDFYKIGEHQFSIQESGVFKKTDEILKKVEKYILEQESYEILYIRKFYFTPRFLSFLK
                     NIRQKFKSILLELPTYPYYGELQTTKAKIGFWIEYFLVIRKLYKYIDKVITFSSDKKI
                     YDIDCIKISNGIDASEQIYFEEPSRDVIHFISVSSISFWHGIDRFILALKNHEEDNVH
                     FHVVGGDNEVSLSLQNMVSEYSLKDKVTFHGHKSGDELKAIYAMSHIGVGSLGRHRSN
                     IYYLNSLKNREYIAKGLPVIYSEIDDGLENLFYVYKVSPNEEPIIISDIITWFKTSDI
                     NRMDVLRDSDKFLWKSQIQAILRNLEK"
     gene            14157..15395
                     /gene="wzy"
     CDS             14157..15395
                     /gene="wzy"
                     /note="oligosaccharide-unit polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzy"
                     /protein_id="QHE90354.1"
                     /translation="MYAELRYDIRNIGFYFVSIIFIVVAFFAIGFSPVFGFIYCLIAL
                     SLGIGKTLIVRSFYSLGAVFSCAVVAASKNYATYNPSDDFSNNYWPVYQDLVNSKSFF
                     DNVFADNYEYFLGFYLKILTYINGTPFNQAQLMFVICFSVLVLFYIWLEALGLKRVAS
                     DKKSLCVAMSIGLFQFLITLQYVRQIFALVFILYAVTFLLEKNKRKALIFFFLACISH
                     TTSIILFPLYILIMKKGKRVTINIAILGGVIAVLFFGIVNFLSALSFGAQFFYKLSYY
                     LQVGDRSNSLAGFKFLIPSLILSKFFFSKNEYLESWKAFQINGAILFSALFFIPELPL
                     RLFGLLIMILPGYLFFLSSYRIGNFFRVIIILYFIFYGYRLIIRDYISLSGTEGDFMG
                     LWYSYPWMGDHLFYYMRSLF"
     gene            15433..16332
                     /gene="gtr112"
     CDS             15433..16332
                     /gene="gtr112"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr112"
                     /protein_id="QHE90355.1"
                     /translation="MNSAIIVLFNPDLIHLNNFIGQLSGQIDKIILVDNTPNSLRKYG
                     DDEFSEENIIYVDLKDNLGIATAHNAGIKKAIEINSEYVIIFDQDSSVPEGFVNSLVC
                     VDKILRSEGKKIAAVGPSYIDIKTNTMAPVIQFNGLKVNRITPKEEELYTSADYIISS
                     GTLIHVDAFKIVGLMMEELFIDYVDLEWGLRAKKMGYQCFVANHVIMKHSIGDRSIKV
                     PFSNKHVNIHSDFRKYFIIRNAFFLILYSNLQANWRIVQIPKTFMYFGFLCLFVSPRL
                     NNVKIFFQAFRDAVTKKMGKGSM"
     gene            16344..17150
                     /gene="gtr82"
     CDS             16344..17150
                     /gene="gtr82"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gtr82"
                     /protein_id="QHE90356.1"
                     /translation="MPKTIASIVLYKHSYAELKATLDSLFATPSIEKVILVDNHSSNW
                     AATFQHPKVVYEKSEGNFGFGYGHNIAIRKYAPKSDYFLICNPDIYFDAEQFAQLLDF
                     AQSRPEGLFLPKIVYDNGEDQHGARLLPTPLNLFARRFSPSFAKKLDQQYLLKDYSLD
                     QPCFVPYLSGCFMLFDAEKLLAIKGFDERFFMYMEDVDLSRRCAEQFGTVYYPLAQVV
                     HVHEQASYKNKQLLKAHLKSAIQYFNKWGWIYDMGRSRLNAKCLDQISKF"
     gene            17191..17793
                     /gene="itrA3"
     CDS             17191..17793
                     /gene="itrA3"
                     /note="initiating transferase for oligosaccharide-unit
                     synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ItrA3"
                     /protein_id="QHE90357.1"
                     /translation="MLKRLVDIIIALSALILLMPVFLIVIYKVRKNLGSPVFFLQERP
                     GKDGKLFKMIKFRSMKDAVDQYGNILPDEERITPFGQKLRSTTLDEMPQLINVLKGDM
                     SIVGPRPQLPDFLQYYTPEQMRRHEVRPGMTGLAQVSGRNNLSWEEKFELDVQYVDTQ
                     SLWLDFKIMFKTAEVMLKKEGINAPDQAVGASRFTGSRDN"
     gene            17824..18699
                     /gene="galU"
     CDS             17824..18699
                     /gene="galU"
                     /note="UTP-glucose-1-phosphate uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GalU"
                     /protein_id="QHE90358.1"
                     /translation="MIKKAVLPVAGLGTRFLPASKSIPKEMVTVVDRPAIEYVVREAV
                     EAGIKQIIFVTHSAKVAIEDYFDHDFELETTLEQKQKFDLLKEITDILPKDVSIVSVR
                     QPKPLGLGHAVLCAKSIVGDNDFAVLLPDVLVKNKSGKNDLARMIERYETVHAAQIMV
                     EAIPDNLVNQYGIVDVPHSPAAGESIAMQGIVEKPAIGSAPSNLSVVGRYILPAKIMQ
                     LLEQTPKGAGNEIQLTDAIALLQQTDAVEAYCMRGQTFDCGSKLGYLKAVLHYGVEHP
                     QLGQAFKMMIAELEQ"
     gene            18717..19979
                     /gene="ugd"
     CDS             18717..19979
                     /gene="ugd"
                     /note="UDP-glucose 6-dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Ugd"
                     /protein_id="QHE90359.1"
                     /translation="MKIAVFGATLHAGVMAALLAEYGNQIYWCTSVTCEENFSILSYQ
                     DQEVNTYLNKQRKAGFLEECSFSGIPLDAEVYLFCYSPTQLQLALNTVEKLSQRPIIH
                     PRLMINGSTFGLQGTQKLKQYLPKDEWVYFPDVIQEGNAINSVLNVKHVIVGAETENA
                     CDIMRELLRPFFRFSYQYLFMPILDAEFTKLSISGMLATRVSYMNDLAMVAEKLGIDI
                     ANVKHGIAADTRIGAAYLSPGVGFGGENFSHDILTLSSTVSETGAKSRLLEQVWEINE
                     QQKEILFRKLWNYYHCDLSGKIVAIWGASFKENTSSIHNSPIHVLLAALWAQGVTVRL
                     HDPQALGEIAKIYGTRDDLILCDDQYDAVTGAQALCVVTAWKQYWGPDFKRLQQSMAH
                     PLILDGRNIYDPAYVKARGFAYEGVGRL"
     gene            19976..21655
                     /gene="gpi"
     CDS             19976..21655
                     /gene="gpi"
                     /note="glucose-6-phosphate isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gpi"
                     /protein_id="QHE90360.1"
                     /translation="MSKNIEQFPKEKLQGSTFASQLRSLGQQYENLHLNELFAAEPER
                     FQKYSVHFDQLFFDYSKHRVNQSVLDQLVTLANAKQLKQWIVRLFSQEKVNCTEQRAA
                     IHWALRLPAGHTQFPELTEQVHTQLQRMYALVEKIHAGQYRGATGEVIQDVVNIGVGG
                     SDLGPLMVTHALSDFKVQTVKPLNVHFVSTMDGSQLSEKLHKLRPETTLFIISSKSFG
                     TIDTLSNAQTVRQWLEKALGKHDRVVKSHFIGVSTKADKMTDWGIAPENQLLLWDWVG
                     GRYSLWSCIGFPIALTIGVKGFQQLLAGAHAIDEHFQHTSFEQNIPVLMALLGIWNNN
                     FLNIQTHAVLPYDGRLKYFAAYLQQLEMESNGKSVQRDGQKVELNTCPIVWGEVGPNA
                     QHAFYQLLHQGTQAVSCDFIAPIQRYNADHFTYVENAKALIEQHHLALSNCLAQSRLL
                     AFGNEALDSTELKNLPIYKQYEGNQPSSTLLLKELNPYSLGMLIALYEHKVFVQSVIW
                     NINPFDQWGVEKGKQIADQLLPILNGAQNDLSSLDASTRGLIKILLGKVDG"
     gene            22097..23938
                     /gene="pgt1"
     CDS             22097..23938
                     /gene="pgt1"
                     /note="predicted phosphoglycerol transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgt1"
                     /protein_id="QHE90361.1"
                     /translation="MIFLRQQLLFILIAFLSISISVYIAWDMNITWYQFYTYLISEKA
                     IFSILFNYAVIQLFFIILGRKYTALCLSQLFVIFLNFINKKKQQYLFSNLSPEDIFLL
                     PEAMTATPWHLQLIFFTLIIFSLIILLIAVRQESKATFHTYVPNIIIFGLISSGLIYL
                     NFIRSPTGACFSENKPMICASLQEFPNTRNDWIGDYRKIQDYGFVTFYVSKVLDNVTS
                     VLLPSRKISEQDIQQILQRHYLVQPLEKNEREYPNIVIVMEESFWDSHHLEIGLPKDL
                     LSFVHQNQVSNLLSPSFGGGTANVEFEVLTSLNTTFFPNELLYVSKLKKPIYALPYYL
                     NSIGYQTFAMHNNYSYYYNRNKVYPDLGFEKFISLENMIAKKDLGKVVNLGGWTTDDL
                     IFDSIKSILKENELQPKFIYAITVENHPMYNDDRFGKQNYKFNKELSETEKQKLSTYT
                     AGTVRANQKLKELAEYLKTVDRPTILVVFGDHLPNLQEVYDSYGFFKDDPERTNLKNY
                     QTPFVVWSNYKLDKKPLKQPYLAASFVAPKLLKLVGLPLSDYYQFVDDVSSCYSVIHQ
                     KFINENLTCNFDKKALLKGYENLNKDVLDGYNHTYKIMQNNQKEMEQ"
     gene            complement(23966..25336)
                     /gene="pgm"
     CDS             complement(23966..25336)
                     /gene="pgm"
                     /note="phosphoglucomutase/phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Pgm"
                     /protein_id="QHE90362.1"
                     /translation="MTTLTCFKAYDIRGKLGTELNEEIAYKIGRAYGQIYKPTTVVVG
                     CDIRLSSGALKQATIRGLNDAGVNVLDLGMTGTEEVYFAAFHLDVQGGIEVTASHNPM
                     DYNGMKLVRENARPISADTGLKEIQSLAETNNFEEVSQKGTTQSYNILPEFVDHLLTY
                     IEPAKIRPLKLVVNAGNGAAGHVIDAIEEKFKALNVPVEFTKIHHEADGTFPNGIPNP
                     ILIENRDSTRNAVLEHKADMGIAWDGDFDRCFLFDEKGQFIEGYYIVGLLAQAFLIKQ
                     SGEKIVHDPRLVWNTFDIVDEYKGVAVQSKSGHAFIKDVMREHNAVYGGEMSAHHYFR
                     DFAYCDSGMIPWLLTIALLSETGQSLSTLVENMIAKFPCSGEINFKVADTQTTIQKIF
                     DFYADQNPQIDRTDGVSLDFGAWRFNVRASNTEPLLRLNIESRADRQAQPMQHYVDEL
                     TGLIQS"
ORIGIN      
        1 ttagtcttct ttttgtgcct tataggcata agcatagtta tagccataac catagccagc
       61 gctagcacgt tgaatatcat tgagaataaa gccgttgact ttaacacccg cctgttcaaa
      121 acgattaaca gttagttcaa gctctttcat ttgtgacttc gcgtagcgtg caacaattaa
      181 gttcacacca gtatattgcg aaataataat accatcggtt accgcaagca ctggtggagt
      241 atcaataatg atgtggtcgt actggctttg tagctgctca agtaattcct taaactggtt
      301 tgagcttaaa atctctgaag gatttgttgg actcttacca cgagtaatca catctagatt
      361 cgttacctga gttttatgta atacttgtga caaatctgcc tgcccactta acaattctga
      421 tagacccggt tttacatcaa catcgaaata tttatgcata taaccacggc gcatatcggc
      481 atcgatcaat agtactcgtt tatcgccttg tgcaaaaata gtcgccaagt tagttgaaat
      541 aaacgatttt cctacctcag gagagggacc agcaatcata atgatattat tttttgcatt
      601 tgctaatgca aagtgaatag ctgtacggat actacgtaag ctctcaatgg caatatcatc
      661 actgttttta accgcaagaa taggaatact cttcttcttc tttaaaatct tgatgcggct
      721 ttcttgaatt ggagaacgag ggacagttgc ataaactggt aaatccaatt cattttcaat
      781 ttggccagaa tctttaatac ctgtacgtaa catattacgt aatagggcaa tcagcgtacc
      841 aataaaacca cccacaaata cagataaaat aagaactaac agttttctag gcttaatagg
      901 ttcaacaggt tcaactgcag tgtcgacaat acgtacatta ccaatttcac cggctttggc
      961 aatacgaagt tgttggtatg aatttaaaag ggctgtatag agctgtgttt taacttcaac
     1021 ttcacgataa agctgtaaat actggcgctg aacatcgggt aattgtttta aagtactatt
     1081 gagttcacca atttgcttat tgatcgcagc gagctggcca ttaatttctc gcattgctgg
     1141 atgttcagcc gtatatttag ctgccatttc agcttgtttt tgttcaagct ctgctttttt
     1201 agtttccaaa gtaatacttt gggttaagta aagctcagat tctttagtca catcaacggt
     1261 gttatactgt tgacggaatt tattaaattg acgctctgca tcatctagct gttttttcag
     1321 gtcaggtagt tgttcatcta aaaattttaa ggtttgagca gattctgccg aacgacgttc
     1381 aatattttgt gcactataag ttgccagaat tgcatttaaa actttagtaa tatgttcttt
     1441 atcttgccct tgatagttaa gacctaaaac acctgtaagt ttgcctcgtt ctgcgacaga
     1501 ataatttacg ctaagggcat ttacagcagc aggtaaagac aaattagtaa tattataggt
     1561 cgcatcgagt tgatctttag taaaaattgc aaccttccag agtccatgtg gcccagtaac
     1621 atgattagct tggttcaacg gaactgttaa tattacctct tcagtttctg gatcagttaa
     1681 agttaaagat tgtttatcaa aattaagaag taagtttttg tctagataat aattcggaac
     1741 ttcaaattca cgcacttcaa aacttttaaa gtcatcttga aataacacag atttttttgt
     1801 gtactcggtt ttatattcgg tgttgcttaa taattggtga gtaagcgtat tttcggtact
     1861 agaaatttgt atatttagat gtaagtcttt aatgacagaa cctaaaacca aacgtgattt
     1921 taaaatttca atctcagctt gagctggtga tttttgctca atcatctgcg ataaatcacc
     1981 tagcagggca gcagaggctc ctttactgtc ttcaacttga accaaagcat caaccgagta
     2041 ggtatctggt gttacacgta aatagagtag agcacacaca aggctcaaaa taatacagag
     2101 cgcaatcagc ttccactgag caatcagtga gaaaaacaat tcttttaaat cgattgtatc
     2161 ttcggtattg gtattttggt tcataagctt aaaatcttgg cgttaaatat aaggtttcca
     2221 gtcagcaata cactgttgaa ttagttgaca ggtttcatca aaaacagttt gatcatgctg
     2281 gtagggatca ggcacattct tattttgcca atgtcctaag cgataggttt taccttttgc
     2341 aaagggccag gtctgctcaa tatgctttag ctggttatta ctcatcacta aaataaggtc
     2401 ggctttttta atatgcgaag cattaagttt tctcgcaata tgaggctgca tatcgatacc
     2461 taagcgttgc atacaaagtt gtgctttatt gtctgcttga tgccctacaa gtccagaaat
     2521 gccagcagac tcaatattta attggggata ttgttgcttc aagaaatatt ctgccatggg
     2581 actacgacag atatttccca cacagacaac taaaatatta ttaatttgca taatattatt
     2641 gtcccaaacg gtctatgtta tataaagcat ttgagaacgg aataatctgg ttaattacac
     2701 gttgccagcg tgttaagcca gtcgcatcga cataaacaat atcattacta cgtaacctaa
     2761 attgattcgc taaaccaaaa tctccaatac tcattaaatt taaatgataa atttcggttg
     2821 tgcggtcatt tgggttactc cgtactacat aaatcttgct agcactaccc gaagttggat
     2881 taatacctaa actttcccct aaagcatcgc ttaaagtcat accttgatca cgcattggta
     2941 atgcttgact ttttccagct tcgcccatca cataaatttt ttgattctca cgtgtgctca
     3001 cataaatagt gtcgtttggt tgaatcaata gcttatggag tgaatagcca gctttttcta
     3061 aatcaatagt atttaagtta taagttcgac catttcgaat aagttgaata taagtgttat
     3121 cacctgttgt agtgacaccg cctgccatac ctaatgcagt ataaatactc accggttgat
     3181 cgcttagata aaattggcca cctttggtaa cactaccttg aacagagaag cgttggcctt
     3241 cataagacac tacacgcact accacatccg gattttttaa aaagcgggct aattggcttc
     3301 gtaactcacg gttgacttga gcaagcgttt taccggcagc tttgtagcgt ccaaccaacg
     3361 gaaactgaat ataaccactt tggtcaatcg ggtaaccatt cgcttgaata gattgttcat
     3421 tactaatatt gtttacagga ggcgtaattt ccggatacgc ccagagctga atagaaagga
     3481 catcgccagg acttaaacgg taaatagatt gttggttttt aaataatgat gcatagtcgc
     3541 gttgataatc gatttgagct ggttgtattg ctggtaatgt ctcttgagaa attttaacta
     3601 catttacggt ggttccgaga tctgttttat aaactccctc acttggaata tcataagttt
     3661 gtaaaccgga agtaaccgca cagctggcag cacttaaact taaggcaaga acagagaaaa
     3721 actggcaata cttcacacgc gaccctttgt gtatttatct ttaattgata ttgtccactg
     3781 catagcgaca agtgtctatt aaacgcaggc tgaactgatt ctagctgaaa agaaatgaaa
     3841 aaacatagaa aaatcgcaag gctttgtatg tttagtttat ctaggctagg cttttaagcg
     3901 gtggtcacag tgtagaaata ttaaaaatgt ataattttgg ctcaattaga aaaggttact
     3961 tataaatgtt gtaaacacat ttatacaatt gacgtacggc gataaatgaa aatctgatat
     4021 agtacgctgc actgttagtg ccaaaagcat gatttattag atataaactc taaggaaaaa
     4081 ggctcgttta tatgcaaatt gccaaattaa aaatagcaat tattggttta ggctatgttg
     4141 gcttgccgtt ggcagttgag tttggaaaaa aggtgccggt tgttggcttt gatatttatc
     4201 aaaaacgtat agatgagctt aagaatggtc aagatcatac cttagaagtt tcacctgaag
     4261 aattaaagca agctgttcac ctcaactata ctgcccattt agatgattta caggactcta
     4321 atttttttat agtcactgta ccaaccccaa ttgatgattt taaacagcct gatttgactc
     4381 ctttaattaa agcctcgacg agtattgggc gggttttaaa aaaaggtgat gtagtggtat
     4441 atgagtccac cgtatatcca ggtgcaacag aagaggtatg tattcctgta ttagaaaaag
     4501 tatctggact caagtttaat caagatttct ttgcaggtta tagtccagag cggattaacc
     4561 ctggtgataa gcagcaccgt gtaactaata ttttaaaaat cacatcgggt tctacacctg
     4621 aggtggctga ttatattgat gaagtttata atttaattat tgaagcgggg acacataaag
     4681 cacctagtat taaagtagca gaagcggcta aagtaatcga aaacacacaa cgtgatgtca
     4741 atattgcttt gattaatgaa ttggctctta tttttaataa attagatatt gataccgaag
     4801 atgtactcaa ggctgctggc acgaaatgga actttctacc attccgacct ggattggttg
     4861 gagggcattg tataggtgta gatccctatt accttactca taaagcccag tctatcgggt
     4921 tgcatcctga aattatttta gcagctcgcc gtttaaatga tcgtatgggt gagcatgtgg
     4981 cgactcagct tataaaagag atggtcaagc aacgtattca ggtggttggt gctcgtattt
     5041 tagttatggg acttagtttt aaagaaaact gtccagatat tcggaataca aaaattgtcg
     5101 actttatcaa cgccttgaaa gagtatgact tagatttaga tatctatgac ccgtgggtga
     5161 atgatacaga agtacaacac gaatatgggt tagcgccaat taaagaatta cagcaaggct
     5221 tgtatgatgc gatcgtcatt gcagtagcac ataaccaatt taaatctatg agtgttgaag
     5281 agtttcatac gttgggtaaa gaaaagtatg tgctatacga tttaaaatat gttttagata
     5341 aagcagattc aaatcttaga ttgtaatcac gatttcatag gtcatcttat ttagtatgaa
     5401 taataataaa attgcgttgg tagtcattgt gtatggcaaa gcattagaag atgctttgac
     5461 tatacaaagc ttgctaggct ttgagcgaaa actggatcat ttacttattg taaataatgg
     5521 tcctacagta atagatgaaa atagtgcagt gttgtctgca ttggcacaaa aacatcacca
     5581 cgttgtttta gaaaatcagg tgcaaaataa gcctttgagt tggatttata atgactttat
     5641 ccagcaatat aatgctgatt attatgtttt atttgatgat gatactgaaa taaatcctga
     5701 gtaccaaaga aaaatattta ttatgcaagg ggtagatata gagttaccta aaatcatttc
     5761 tatgaatgat aaagcacaat attatccctt agttgatggg gtgatagagc aaaaggatgg
     5821 aataatctct aatgcaaaag aaatattctc aattggctca ggtttggtga tttctaaaga
     5881 cataaaacaa tattttatag aaaacaaaat tgagttgttc gattcacact ttgctctcta
     5941 tggggtagat tttagtttct tcagaaagat taatcatata gcaaaacaaa aaaatataat
     6001 tttttcaatt tcttccaata catatattaa acactcttta tcacgtactg aaaaagaaac
     6061 aaatgcatgg cgtgataaag aaagattata tgacttagtc ttgacactaa aatactatta
     6121 ttcttacgct gaattacgaa ttttaaagtt atttttcaag aaaatattgg gtggaaaaat
     6181 aaaagatgca ttgctcattt taagcactac atttaatggt gctcatccaa gatgtatgaa
     6241 taaagtattg aatgattgag gtctccaaag tgttagaaga taggatagat attgcattag
     6301 ctacatacaa tggagaaaaa tatattacag aattattgga ctctcttgat caacagactt
     6361 atcaaaattt tattgtacat gtttgtgatg atggttccaa agatcggaca atagctattt
     6421 gtgaagcgca ttctttattt aaaaagggca aactagagat ccatgaaaaa actggaggaa
     6481 atggtgcttc aaggaatttt attcgaacac tttcctactg taaaaatcca tatattgctt
     6541 tgtgtgatca ggatgatttt tggatcccta ccaaacttga gaaaatgttg gttaagaccc
     6601 aacatgaaga aggatcagaa aaaaagccaa cattaatttt ttcagatcta caaatagtgg
     6661 atgaaaaatt acatatactt tcaccttctt actttgcggt ttcttctaaa agtaatcaat
     6721 gttccactcc atttgatttt ttgttgagca accatgtgcc tggttgtacc atgatgttta
     6781 accaatcact aaagcaagta tttgaaccta ttcctcaaga attcaggatg catgattggt
     6841 ggattattct catagcagct ttttggggaa gagtcattta tttagatgaa agcttaattc
     6901 aataccgcca acatgggaat aatactgtag gtgcggtagg aatggataaa cctactttaa
     6961 tacaaaagct tcgtacagta ttgttatata aaacgatact attaaaagta gatatggtga
     7021 gaaaaagttt cttaccttat atccagcaaa aagagattca acaagaaaaa ctttctttgg
     7081 agcaaaaaaa atttatagat ttattgcaaa gacgacttcc gctttcaaag agactccaga
     7141 tttttagtaa aacagtaaca ggcgaagatc gtttactcag ttttttagtt tggtgtttat
     7201 tatgagtaag gcaataaata aagaagtttt ttatttatat attattcaaa tcgccaatat
     7261 ggttattcca ctgttgtcat tttcctatat ggccaatatt ttaggattgg taggatttgg
     7321 gcaagttagc ttctatcaaa cagtaagttt cctagcagca ttttttattg actttggttt
     7381 caatatgtct gcagcgcaga agatgagtat cagtctcgat gataaatcga aaatggatga
     7441 gctttatagc aatgtgcaaa gtgcaaagtt tttcattttt ttaattgtat cagtactggg
     7501 cgggataggg gtgttgttgt tacctttgtc tcatatagat gcaaccttat tatttattgg
     7561 tattctttca gctttcagta caattttgct gtctggctgg gtttttcaag gacttgggcg
     7621 taactcagtt ttagctttct tttctgttat tggacgggtt gtctcagttg ggttaatttt
     7681 ttggttaatt catcaaaaaa gtgatgtgtt gcttgcagtt ataattcaag ttgcaattag
     7741 tttttcaatt ggtttggcag caattatcta tttttatcga aaaaatgtag taacttttcg
     7801 gtttaaatct atttctatct ataaaataaa acaactgtca gaggacagct atcataactt
     7861 tactgcatca ctttttactt tgggatttac ctatttaaat ccaataatcg tgaaattctg
     7921 ttttggtgat gcttttttag ggttgtatgc tatggctgat aagttggcgg tagttattaa
     7981 acagcttttt actccggtta cacaggctta ttatagtcga atgtgtattt tgagccatga
     8041 aaaaaaatat caagagttaa tacaaaatgc aaagaaagtt gctatctttt ttgctggcat
     8101 tagtattgtg gcctttgccg gcaatctatt gattggtaaa tatatttata gttttttatt
     8161 tggaccagaa tataaaatca caagtttatt aagtattatg attatgacgc aatttgttgt
     8221 gtctatggcg atggtacttg ttaatttaat tattattcca acagaaaata gtagaatttt
     8281 gaagaaatac tatcttatag gtttaatttt tcacttcggc tatttttatt tctttgttaa
     8341 atatttacat atttatggag ttgctagtgc tatcttgcta accgaaacaa ttcttacact
     8401 gtcattcttt atgtatgtaa gaaaatactt ttcaaaagtt ttaacgtaaa tctaaaggtt
     8461 attttatgaa aataacagta gttggtacag gctacgtggg tttatcaaat gcgatgttgt
     8521 tttctaaaca gcatgaagtg actgccctcg atattgatgc cacaaaaatt gataaactta
     8581 atcaaggcat atctcctatt catgatgacc ttattcaaga atatttgatt gataattcaa
     8641 attttaaagc aacattagat aaaaattctg catatgtaga tgcggaagtc attattattg
     8701 ctacacccac caattacgat gaagcaagca attatttcga tacgagttcg attgaatctg
     8761 tgcttgaaga tttaaaccac ttaaaaagcg atgcgattat tgtggtgaag tctacaattc
     8821 ctgtcggttt tactgagcgt atgaaggaga ctttttcagc attgaaagtt gttttttctc
     8881 cggaattttt acgtgaaggc aaggcattat acgacaactt gtatccgtca aggatcgtgg
     8941 tgggtaatac ctcggaagtt ggtgcattag ttggacaatt atttaaaaat gctagtttaa
     9001 gacctgatgt agatgtacta caaatggatg caacggaagc tgaagctgta aagcttttct
     9061 caaatactta tttggcaatg cgtgttgctt attttaatga gttagactca tattgtgcat
     9121 cacgtggact aaactcaaaa gatattattc aggctgtagg tttagatcca cgtattggag
     9181 cacattataa caatccatca tttggttatg gtggatactg tttaccaaaa gacacaaagc
     9241 aattgctagc caattatcaa gatgtcccgc aaaatttgat cggagcaatt atccagtcaa
     9301 atacaacacg aaaagatttt attgccgagc aaattttggc aagaaaacca aaagtggttg
     9361 gtgtatatcg tttagtaatg aaacaaggtt cagataactt tagacaatct gcaattcaag
     9421 gtgtaatgaa gcgtctaaaa gccaaaggtg tagaagtcat tgtgtttgag ccgagtttaa
     9481 atgagtcaac attttttaac tcacgtgtgt tgaccgattt tgatagtttt aaacaagagt
     9541 cggatgtaat tattgcaaac cgtatggtga gtgagctcga agacgtcatt gacaaagttt
     9601 atactcgtga tttatttggt gaaaattaat tatacttagg tagttgtatg aaaattttaa
     9661 ttactggtgg cgctggtttt attggttcag cggtcgttcg tcatattatc cagaatacag
     9721 aagatgaagt attaaatgtt gataaactga cctatgcagg aaatttagaa tctttaattt
     9781 ctgtggaaaa taatccacgt tatcagtttt ctcaaacaga catttgtgat cgagctgctt
     9841 tagataagct atttgagaca ttccaaccag atgcagttat gcatcttgcg gcagagtcac
     9901 atgtagaccg ttctattact ggtccttatg cttttatcga gactaacgtg attggtactt
     9961 accaaatgtt ggaggcgagc cgtgcttact ggttaagtct aagtgatgaa aagaaagcag
    10021 ctttccgttt tcaccacatt tcaaccgatg aagtttatgg tgatttagaa ggaactaccg
    10081 acttatttac tgaaactaca tcatactcgc caagctcacc atattcagca agtaaagcaa
    10141 gttcagatca tttagttcga gcatggaatc gtacgtatgg tttgccagtg ttagtaacta
    10201 actgttcaaa taactatggc ccattccatt tccctgaaaa acttatccca ctcatgattt
    10261 taaatgccct acaaggcaaa tcattgccag tatatggcaa tggtcaacaa attcgtgact
    10321 ggttgtttgt agaagatcat gcacgtgcgc tttatacagt ggttacgcaa ggtactgtag
    10381 gtgaaacata taatattggt ggacataacg aaaaagctaa ccttgatgtt gtacatgcaa
    10441 tttgtgatct acttgaagaa cttgcaccac ataaaccgga aggtgtagca cagtataaag
    10501 atctgattac atatgtgaaa gatcgtccag gccatgacgt gcgttatgca attgatgcga
    10561 ccaaaattaa agaagaactc aactgggtac cgaaagagtc atttgaaact ggtttacgta
    10621 aaacagttga atggtattta aataacaaag agtgggttga acacgtccaa agtggtgaat
    10681 accaatcttg gttaaacaag caatatcaag gataactatg aaaatcttat tgcttggaaa
    10741 aaatggacaa gtggggtggg agctgcaacg cgcgcttgca cctttaggtg atgtcattgc
    10801 tttagatcgt catggtttag atagcttgtc tggtgatatg acccaaccac aggcgattta
    10861 tgacacgatt ttggcagtac agccagatgt tgttgtcaat gcttctgcat atacagccgt
    10921 tgatttggca gaaactgagc aagaactagc tgatattatc aatcaccaaa ctgtaaaagc
    10981 ggcagcagaa gcctgtcagg aaacaaatgc tttattggtg cattattcaa cagactatgt
    11041 ttttgaaggt acaggaacga ccgcttttgt tgaaactgat gtaattgcgc cattaaatat
    11101 ttatggaaaa accaaagctt tgggtgagca agcgattgtt gatagtggct gtcgctattt
    11161 aatattcaga acttcgtggg tatatgcttc aagagcgaaa aattttttga aaactatgtt
    11221 gagcctagct caacaacgcg aagaattgtc aattattgat gatcagattg gtgcaccaac
    11281 ttcagctgaa ttgattgcag acatcaccgc gcaggctatt ccacaaactg tggcagacgc
    11341 aaacaaagtt ggtatttatc acttggtagc aagtggtgag acttcttggt ttggctacgc
    11401 aaactatgca tttacacaag cacgtacttt ggggcaagag ttggcgatac aaaaggttaa
    11461 cccgatccca acaagtgctt acccaacgcc tgcaacacga ccacacaatt cacgattaga
    11521 taatcagaaa atacaacgca cttttggatt gactctacca gtctggcaag aaggtgttaa
    11581 acgcgcatta atggagcttt taaacaaatg agcttaaaac gtaaaggtat tattttagcg
    11641 ggcggttcag gtacacgctt gcacccaatt actaaaggtg tgtcaaaaca gcttttgccg
    11701 atttacgata aaccaatgat ttactatccg ctttcagtac ttatgctcgc gggtattcgt
    11761 gaagtattga ttatttcaac tccggaagac ttaccaaact ttgaaaaact tttgggtgat
    11821 ggttcgcaat ttggtattga actcagctat aaagtgcaac cttctccaga tggcttagct
    11881 caagctttct taattggtga agagtttatt ggtcaagaca atgtttgctt gatcttggga
    11941 gataatattt accatggtca gcacttcagt catcaattag aggctgcttc tgcacgtgaa
    12001 catggagcaa cggtgtttgg ctatcatgtg acagatcccg agcgttttgg tgttgttgaa
    12061 tttgataaaa ctggtaaagt gctaagtatt gaagaaaagc cagcccagcc aaaatcgcct
    12121 tatgcagtaa caggtttata tttctatgat aaccgtgtcg ttgagtttgc aaaacaggtg
    12181 aaaccatctg cacgtggtga gctggaaatt acagatatta ataacgctta cttacaagat
    12241 ggttcactta atgttgaatt acttggccgt ggttttgcat ggttagatac aggcacacat
    12301 gaatctttgc ttgaagctgg tcattttatt tataccattg aaaagcgtca gtcttttaaa
    12361 gtggcatgtt tggaagaaat tggcttccat caaggctgga ttagtaaaga acagctttta
    12421 gatagtgcgg aagcattgaa aaaaaccgaa tatggtcaat atttgaaaaa agtttgggaa
    12481 gaatcaaatg aaggttgaaa cgactaaaat tgaagggctt ttgattcttc atccaagtgt
    12541 ttttggtgat gaccgtggtt ggtttatgga aagttttaac caacaacgct ttgctcaagc
    12601 acttgaagat ttaaatttgc cagttccgac ttttgtgcaa gataaccatt cattgtcaca
    12661 aaaaggtgtg ttgcgtggtt tacactatca aaacgcaccc tatgcacaag gaaaactggt
    12721 acgtgttgta caaggtcgcg tttgggatgt ggctgtagat attcgcccag actcaaaaac
    12781 ctatggtgaa tgggttgggg tagaactcag tgcagagaac aaaactatgt tttggattcc
    12841 tgaaggattt gcccatggtt ttatctcttt agaagataat acccagttct tgtataaaac
    12901 cacaaactac tacaacaaag aaagtgaagg ggccattatt tggaatgacc caacacttgc
    12961 aattgactgg cctttggcgg aagttgatga agtattggtg agtgataaag atcaggttgc
    13021 aaaggaattt aagaaataaa caatgaagaa ggtcttcttt ttaaccaatg cggtagattt
    13081 agctaattca agtgatggat tggctaaaaa gatacatgca caaactaaag cctttcaaga
    13141 ctgtgggtat gtaacagaac tagcgggttg ttcagaagac ttttataaaa ttggagagca
    13201 ccagttttca attcaagaat ctggtgtttt taagaaaact gatgaaatat taaaaaaagt
    13261 tgagaaatat attcttgagc aagagagtta tgagatcctc tatataagga agttctattt
    13321 tactccgaga tttttatcct ttttaaagaa tattcgacaa aaattcaaat ctattttatt
    13381 agagttgcca acttatccat attatggtga attacaaacg accaaagcaa aaattggatt
    13441 ttggatagag tattttttag tcattagaaa actatataaa tatattgata aagttataac
    13501 cttttcaagt gataagaaaa tatatgatat tgattgtata aaaatatcta atggtattga
    13561 tgcttcagag caaatatatt ttgaagaacc aagtagagat gtaattcatt ttattagtgt
    13621 atcttctatt agcttttggc atggaataga tcggtttatc ttggcactaa aaaatcatga
    13681 agaagataat gtacattttc atgtggtggg tggagataat gaagtttcgt tatcactgca
    13741 aaatatggtg agtgaatata gtttaaaaga taaagtaact tttcatgggc ataaaagtgg
    13801 ggatgagtta aaagctatat atgctatgag ccatattggt gtaggaagtt tagggcgcca
    13861 tagaagtaat atttattatt taaattccct gaaaaataga gaatatattg caaaaggttt
    13921 gcctgttatc tactcggaaa tagatgatgg tttggaaaat cttttttatg tatataaggt
    13981 tagtccaaat gaagaaccta ttatcattag tgatattatt acatggttta aaacttcaga
    14041 tattaatcga atggacgttt taagagattc agataagttt ctatggaaaa gtcaaataca
    14101 ggctattcta agaaatttag aaaaataagc ttttaaggaa ttattggtat ctgattatgt
    14161 atgctgaatt acgatatgat attagaaata ttggatttta cttcgttagt ataatattta
    14221 ttgttgttgc cttttttgca attggctttt ctcctgtctt tggctttatt tattgtttaa
    14281 ttgcattatc tctaggaata gggaaaacgt taattgtaag aagcttttat tcattagggg
    14341 ctgtatttag ttgtgcagtg gtggcagctt caaaaaacta tgctacttat aatccatctg
    14401 atgatttttc taataattat tggcctgtat atcaagactt ggtaaacagt aagtcttttt
    14461 ttgataatgt atttgcagac aactatgagt attttcttgg tttttattta aaaattttaa
    14521 cctatataaa tggtacaccc tttaaccaag cccaattaat gtttgttatt tgtttcagtg
    14581 ttctcgttct tttttatatt tggcttgaag ctttaggttt aaaaagagta gcttctgata
    14641 agaaatcttt atgtgttgca atgtctatag gtcttttcca attcttaatt acattgcagt
    14701 atgttaggca aatatttgca ttagttttta tactatatgc tgtaacattt ttattagaaa
    14761 aaaataaaag aaaagcttta attttcttct ttctggcatg tatttctcat actacttcta
    14821 ttatattgtt tcctctgtat attttgataa tgaaaaaagg aaaacgagtt actattaata
    14881 tagctatttt aggaggtgta atagctgttt tattttttgg tatcgtaaat tttttatcag
    14941 ctctgtcttt tggtgcgcaa tttttttata agctcagtta ttatcttcaa gtcggtgata
    15001 gatcaaattc tcttgctgga tttaaatttt tgataccaag tttaattcta tctaaattct
    15061 ttttttctaa aaatgagtat ttagaatctt ggaaagcatt tcaaataaat ggagcaatat
    15121 tattttcagc attatttttt atacctgaat tacctttaag gctctttggg cttttaatta
    15181 tgattcttcc tggatattta ttttttcttt cttcatatag gattggtaat ttttttagag
    15241 ttattataat tttatatttt attttttatg gttatagatt aattatccga gactatatta
    15301 gtttaagtgg tacggaaggt gactttatgg gcttgtggta cagttatcca tggatgggag
    15361 atcatttatt ctattatatg cgtagtctgt tttaagtaat acttttttct tttactaatt
    15421 tagagttctt ttatgaatag tgcaataata gttttattta atcctgattt aatacatctt
    15481 aataacttta taggccagct aagtgggcaa atcgacaaaa ttattttagt tgataataca
    15541 ccaaattctt taagaaaata tggtgatgat gagttttctg aagaaaatat tatctatgtt
    15601 gatttaaaag ataatttagg tattgccact gcacataatg caggtattaa aaaagcaata
    15661 gaaattaatt ctgaatatgt cattatattt gatcaggatt catctgtacc agaaggcttt
    15721 gtcaactctt tagtttgtgt tgataaaata ttaaggagcg aagggaaaaa aattgcagca
    15781 gttggcccct cttatattga tattaaaact aatacgatgg ccccagtaat tcagtttaat
    15841 ggtttgaagg ttaatagaat aactcctaaa gaagaggaat tatatacttc agcagattac
    15901 atcatctcgt ccggtacact catccatgtt gatgctttta aaatagttgg attgatgatg
    15961 gaagagttgt ttattgatta tgttgatttg gaatgggggt tacgtgccaa gaaaatgggt
    16021 tatcagtgct ttgtggcgaa tcatgttatt atgaaacatt ccattggtga tcgttcaata
    16081 aaagttcctt tctcaaataa acacgttaat attcattctg attttagaaa gtattttatt
    16141 attagaaatg catttttttt gattctatat tcaaatttac aagcaaattg gcgtattgtg
    16201 caaataccga aaacatttat gtactttggt ttcttatgtt tatttgtgtc accgagattg
    16261 aataatgtga agatattctt tcaggcattc agagatgcag taacaaaaaa aatgggtaaa
    16321 ggaagtatgt aatggtcgat aacatgccta aaaccattgc ttcgatcgtt ttatataaac
    16381 atagctatgc tgagttaaaa gcaacactcg acagtttatt tgccacgcca agcattgaaa
    16441 aagttatttt ggtagataac cattcaagta actgggctgc aacatttcaa catcctaaag
    16501 ttgtttatga aaaatcagag ggtaactttg gttttggtta tggacataat atcgccatcc
    16561 gtaaatatgc gccaaaaagc gattattttc tcatttgtaa cccagatatt tactttgatg
    16621 ctgagcaatt tgcccaattg ttagactttg ctcaaagccg acctgaaggt ttgtttttac
    16681 caaaaattgt ctatgataat ggtgaagacc aacatggtgc acgcttatta cccacccctt
    16741 taaatttatt tgctcgtcgt ttttcacctt cttttgctaa aaagcttgat caacaatatt
    16801 tgttaaaaga ttactcactt gatcagccat gtttcgtacc ttacctttca ggttgcttta
    16861 tgttatttga tgcagaaaaa cttttagcaa ttaagggatt cgatgaacgt ttctttatgt
    16921 atatggaaga tgtggattta tctcgtcgtt gtgcagagca atttggtact gtgtactatc
    16981 cattagcaca agtagtccat gttcacgaac aagcatcata taaaaacaaa caattactta
    17041 aagcacactt aaaaagcgcg atacaatact ttaataaatg gggatggatt tatgacatgg
    17101 ggcgtagtag gcttaacgca aaatgtttag accaaatctc taaattctaa ataatgaagc
    17161 ttttaaaatg aaattagtag gtatatccag atgttaaaaa ggcttgtaga tattatcatt
    17221 gccctatctg ccttaattct tctaatgcct gtttttttga ttgtaattta taaagttagg
    17281 aaaaacttag gttcccctgt ctttttctta caagaacgtc cgggcaaaga cggtaaatta
    17341 tttaagatga ttaaatttcg ttctatgaag gatgcggttg atcaatatgg caatatttta
    17401 ccagatgaag agcggattac cccttttggg caaaagttac gttctactac actcgatgaa
    17461 atgcctcagc tgattaatgt acttaaaggc gatatgagta ttgtaggacc acgcccacag
    17521 ttacctgatt ttttacaata ttacacgcca gaacaaatgc gccgtcatga agttcgtcct
    17581 ggtatgactg gacttgccca agtgagtggc cgcaataatt tgagttggga agaaaaattt
    17641 gagctagatg ttcagtatgt tgacacgcag agtttatggc tcgattttaa aattatgttt
    17701 aaaacagcag aagtcatgtt gaaaaaagaa ggaattaacg caccggatca agcagtaggc
    17761 gctagtcgtt tcaccggttc aagagataat taagttttgt aaataatagt tggtaacagt
    17821 tcaatgatta aaaaagcagt tttaccagtt gcaggtttag gcacccgttt tttaccagca
    17881 agtaaatcga tacccaaaga aatggttaca gttgttgatc gtcctgctat cgaatatgta
    17941 gtacgtgagg cagttgaagc aggtatcaaa cagattattt ttgtgactca ctctgctaaa
    18001 gttgctattg aagattattt tgaccatgac tttgagctag aaactacatt agaacaaaaa
    18061 caaaaatttg acttacttaa ggaaattact gacattttac ctaaagatgt gagtatcgta
    18121 agtgtacgcc aaccgaaacc tctaggctta ggacatgccg tactttgtgc taaaagtatt
    18181 gtcggtgata atgactttgc tgtgctttta cccgatgtac tagttaagaa taaatcaggg
    18241 aaaaatgatt tagcccgtat gatagagcgt tatgaaacag tacatgctgc tcagattatg
    18301 gttgaagcta taccagataa cttagttaat caatatggta ttgttgatgt gccccattca
    18361 ccagccgctg gtgaaagtat tgccatgcaa ggcattgttg aaaagcctgc tataggttct
    18421 gcaccgtcaa atttatcagt agttggacgt tatattttac cagcaaaaat tatgcaactt
    18481 ttagaacaaa ctcctaaagg tgctggtaat gaaattcaac ttaccgatgc aattgcccta
    18541 ttacagcaaa cagacgccgt agaagcttac tgtatgcgag gtcaaacttt tgactgtggt
    18601 agtaagttag ggtatttaaa ggcggtatta cattatggtg ttgagcaccc gcaattaggg
    18661 caagcattta aaatgatgat tgccgagtta gaacaataag atattgtagg tgtaaaatga
    18721 aaattgcagt ttttggtgca actttacatg ctggtgtaat ggcagcatta ttggctgagt
    18781 atggtaatca aatctattgg tgtacaagtg taacctgtga agaaaatttt tctatacttt
    18841 cttatcaaga tcaggaagtt aatacttatt tgaataagca gagaaaagca ggttttttag
    18901 aagaatgttc tttttcaggg atccctttag atgctgaagt ttatttattt tgttatagtc
    18961 caacgcaatt gcaacttgca ttaaatacag tagaaaaact tagccaacgg ccaattattc
    19021 accctcgttt aatgattaat ggttcaactt ttggtttaca gggaacccaa aaacttaaac
    19081 agtatttacc aaaagatgaa tgggtttatt ttcctgatgt tattcaagaa ggaaatgcta
    19141 ttaatagtgt cctcaatgtg aaacatgtga ttgttggagc ggaaacagaa aatgcatgtg
    19201 atatcatgcg tgagttacta cgaccatttt tccgtttcag ttatcagtat ttatttatgc
    19261 caatattaga tgctgaattt accaaattaa gtatttcagg catgttggca acacgtgtca
    19321 gctacatgaa tgatttagca atggtagctg aaaaactcgg gattgatatt gctaatgtaa
    19381 aacatggtat tgctgctgat acacgtattg gcgcagctta tctatcgcct ggtgtgggct
    19441 tcggcggtga aaatttttca catgatattt taacactttc gagtactgtg tctgaaacag
    19501 gagctaaaag tcggttatta gaacaggttt gggaaattaa cgaacaacaa aaagaaattt
    19561 tattccgtaa gttatggaat tattatcatt gtgacttgag cggcaaaatt gttgcaattt
    19621 ggggtgcttc atttaaggaa aatacctcca gtattcataa ttcccctatt catgttttgt
    19681 tagctgcttt atgggctcag ggagtaacag tgcgtttaca cgacccacaa gctttaggtg
    19741 aaattgcaaa aatatatggt acacgtgatg atttaatatt atgtgatgac caatatgatg
    19801 cagttacagg tgctcaagcg ctttgcgtag taaccgcatg gaagcagtat tgggggccgg
    19861 attttaaacg tttacaacaa agtatggctc atcctctaat tttggatgga cgtaatattt
    19921 atgaccctgc atatgttaaa gctcgaggtt ttgcatatga aggagtaggt cgtttatgag
    19981 taaaaatata gaacaattcc cgaaagagaa gctgcagggc tcaacatttg cctcacagtt
    20041 aagatcatta gggcaacaat atgaaaatct tcatttaaat gagctatttg ctgcagaacc
    20101 agagcgcttt caaaagtatt ctgttcattt tgatcaactt ttttttgatt atagtaagca
    20161 ccgtgtaaat caatctgttt tagatcagtt ggtgactttg gcaaatgcca aacaattaaa
    20221 acagtggatt gtacgtttat tttcacaaga aaaagtaaac tgtacggaac agcgtgcagc
    20281 aatacattgg gcattacgtt taccagcagg acatacccaa tttcctgagc tcactgaaca
    20341 ggtacataca caattacaac gtatgtatgc attggttgaa aaaattcatg ctggtcaata
    20401 tcgtggtgct acgggtgaag tgattcaaga tgtagtaaat attggagtgg ggggatctga
    20461 tttaggtcca ctcatggtca ctcacgcatt gtctgacttt aaagtacaga cagtaaagcc
    20521 tttaaatgta cactttgttt ctacaatgga cggcagtcag ctttctgaaa aactacataa
    20581 gctgcgcccg gaaacaactt tatttattat ttcctcaaag tcatttggta ccattgatac
    20641 tttatcaaat gcacaaacag ttcgtcagtg gcttgaaaaa gctttaggaa agcatgaccg
    20701 agttgtaaaa agtcacttta ttggtgtgtc tacaaaagct gataagatga cagactgggg
    20761 aattgcccct gaaaaccagt tgctactttg ggattgggtg ggtggtcgct attctctctg
    20821 gtcttgtatt ggtttcccta tcgctttgac aatcggcgtt aaaggtttcc aacagctttt
    20881 agctggagcc catgctattg atgaacattt tcaacataca agttttgagc aaaatatacc
    20941 ggttctcatg gcattattgg gaatctggaa taataatttt ttaaatattc agacccatgc
    21001 agtattaccc tatgatggga gattaaagta ttttgctgct tatttacagc agcttgaaat
    21061 ggagtctaat ggtaagtcgg tacaacgtga tggtcaaaaa gttgaattaa atacttgtcc
    21121 aattgtatgg ggggaggttg gtccaaatgc gcaacatgcc ttttaccaac tcttacatca
    21181 agggactcag gcagtaagtt gtgatttcat tgcaccgata caacgttata atgcggatca
    21241 ttttacctat gtagaaaatg ctaaagcatt aattgagcaa catcatttag cgttatcaaa
    21301 ttgtttggca caatcacgtt tattggcttt tggcaatgag gctttggatt caactgaatt
    21361 aaagaatctg ccaatttata aacaatatga aggtaaccag ccaagctcca cattattatt
    21421 aaaagaactt aatccatata gcttgggtat gctgattgct ttatatgaac ataaagtatt
    21481 tgttcagtct gtgatttgga acattaaccc atttgatcaa tggggtgttg aaaaaggtaa
    21541 gcagattgct gatcagttac ttccaatttt aaatggtgct caaaatgatc tttcatcgct
    21601 tgatgcttcg acgcgtggtt tgattaaaat tttattagga aaagttgatg gttaatattc
    21661 taaccactgg cgttgcgggt atacttcgct tctactgaag ctacccatag ctatgctatc
    21721 caataactat gagtatacaa agctgattgt cgagcaaata ttgtaaaaaa attaatggct
    21781 aactctaaat agtcatttgt tttactcgac tatttcaata ctataggagt atataagtga
    21841 acaagatata ctccggtttt gagtatgctt cagcgggggg cagctctttt gctaaaaaat
    21901 gctcttgcag ttctgagttg ttgtgataga aacctttata gggcttaaaa gatctgctta
    21961 aggatagttg gagatgtaag aattgttcaa ctcgatataa aaattgatta tttaattttt
    22021 ctgaaagcgg ctacagttat agtgaatgct tccatgctag tatttgccac aatcctgtta
    22081 gcctcttttt gtagtcatga tttttctacg tcaacaactg ctatttatcc ttattgcctt
    22141 cttatccatc agcataagtg tatatatagc atgggatatg aatataactt ggtatcagtt
    22201 ttatacttat ttgatttcag aaaaggctat tttttcaatt ctttttaact atgcagtcat
    22261 tcagttattt tttattattc ttggacgtaa atatactgca ctgtgtttaa gccaattatt
    22321 cgttatattt ttaaatttta ttaataaaaa gaagcaacaa tatttattta gtaatttaag
    22381 tcctgaagat attttcttac ttccagaagc aatgacggcc accccttggc atttacagct
    22441 tatctttttt accctcatta ttttttctct tatcatactc ctcattgctg tacgccaaga
    22501 aagtaaagcg acttttcata cttatgtccc taatattatt atctttggat taatcagtag
    22561 tggtttaatt tacttaaatt ttattaggag ccctacaggc gcttgttttt ccgaaaataa
    22621 acctatgatt tgtgccagct tacaggaatt cccgaatacc agaaatgact ggatcggtga
    22681 ttaccgaaaa attcaagatt atgggtttgt gactttttac gtttctaaag tattggataa
    22741 tgtaaccagc gtattgttac ctagtcgtaa aatatctgag caagacatac agcaaatttt
    22801 gcagcgacat tacttggttc aacctttaga aaaaaatgag agagaatatc cgaatattgt
    22861 tattgttatg gaggagtctt tttgggactc tcatcattta gaaattggat tacctaaaga
    22921 tttattatct tttgttcacc aaaatcaagt ttctaattta ttgtcgcctt catttggtgg
    22981 aggtacagcg aatgtcgagt ttgaagtact tacgagcctc aatacaactt ttttcccaaa
    23041 tgaattgtta tatgtttcta agctaaagaa gccaatttat gctctacctt attatttaaa
    23101 ttcaattggt tatcaaacat ttgcaatgca taataattat agttactact ataatcgtaa
    23161 taaggtatat ccagatttag ggtttgagaa atttatatcg cttgaaaata tgattgctaa
    23221 aaaagatctt gggaaagtgg ttaatttggg tggttggacg acagatgatc ttatttttga
    23281 ttcaattaag tctattttaa aagagaatga gctacagcca aagtttattt atgcaattac
    23341 tgtcgaaaat catccaatgt ataatgatga ccgatttggc aaacaaaatt ataaatttaa
    23401 taaagagttg tctgaaactg aaaaacaaaa gctaagtact tatactgctg gaactgtgcg
    23461 tgctaaccaa aagttaaaag aactcgctga atatttaaag acagtagatc gaccaacaat
    23521 tttagtagtt tttggtgatc atttgcctaa tttacaagaa gtttatgata gctatggttt
    23581 ttttaaagat gatcccgagc gaactaatct aaaaaattac cagactccgt ttgtagtgtg
    23641 gagcaattat aaattagata agaagccttt gaagcaacct tatcttgctg caagtttcgt
    23701 tgctccaaaa ttattaaagt tagtaggact accgttgtca gattactatc aatttgttga
    23761 tgatgtctcg agttgttata gtgtcattca ccaaaaattt atcaatgaaa atctaacgtg
    23821 taattttgat aagaaagcgc tgttaaaagg ttatgaaaat ctaaataagg atgtattaga
    23881 tggatataat catacttata aaattatgca gaataaccaa aaagagatgg aacaataatg
    23941 ttccatctct ttgagatgaa ccctattaag actgaattaa tccagtcaat tcatctacat
    24001 aatgttgcat tggctgagcc tggcggtctg cacggctttc aatattaaga cgtagtaaag
    24061 gctcggtgtt tgacgcacgg acattaaaac gccacgcacc aaagtcgagg cttaccccat
    24121 cggtacggtc aatttgtgga ttttgatcgg catagaagtc gaaaatcttt tgaatcgtag
    24181 tttgtgtatc ggctacttta aagttgattt caccactaca agggaacttg gcaatcatat
    24241 tttcaacgag tgttgagaga gattgtcctg tttcagagag tagagcaatg gtgagtaacc
    24301 agggaatcat accactgtca cagtaagcga aatcacggaa atagtggtga gcactcattt
    24361 caccgccgta tacggcattg tgttcacgca taacatcttt aataaatgca tgccccgatt
    24421 ttgactgtac agcaacacct ttatattcgt cgacgatatc aaatgtgttc cacactaaac
    24481 gtgggtcatg cacaattttt tcgcctgact gtttgattaa gaaagcttga gccaataggc
    24541 caacaatata gtagccctca atgaattgtc ctttttcatc gaacaagaaa cagcggtcaa
    24601 agtcgccgtc ccatgcaata cccatatctg ctttatgctc aagaacagca tttcgggtac
    24661 tgtcacggtt ttcaattaaa attgggttag ggatgccatt tgggaaagta ccatctgctt
    24721 catgatgaat tttagtaaat tcaaccggta cattaagtgc tttaaatttt tcctcaatgg
    24781 catcaattac atgaccagct gcaccattgc ccgcgtttac cactaacttt aagggacgga
    24841 tttttgcagg ttcaatataa gtcagtagat ggtcaacgaa ctcaggcaaa atattatagc
    24901 tttgagttgt gcctttttgg ctaacttctt caaagttatt ggtttctgct aaggactgaa
    24961 tttcttttaa accggtatcg gcactaattg gacgagcatt ttctcgaacc aatttcatac
    25021 cgttatagtc cattgggtta tgactcgcag ttacttctat accaccttgt acgtctaaat
    25081 gaaaagctgc aaagtaaact tcttcagtac ccgtcatacc tagatcaagc acattcacac
    25141 ccgcatcatt taatccacgg atggtcgctt gttttaaagc cccactgctt aggcgaatat
    25201 cacaacctac aaccacagtc gttggtttat agatttgtcc gtaagcgcgg ccaattttat
    25261 aggcgatttc ttcattcaat tcggtgccga gtttacctcg gatatcataa gctttaaaac
    25321 acgttaaagt agtcat
//

