CAZyme Information: MGYG000000289_01167

Basic Information

• Species: Prevotella buccae
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella buccae
• CAZyme ID: MGYG000000289_01167
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
847	MGYG000000289_13|CGC1	96830.23	7.1928

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000289	3001000	MAG	Sweden	Europe

• Gene Location: Start: 50027; End: 52570 Strand: -

Full Sequence      

MVRRLFLKDSSPIFIYMKTSIYLLLLLLFSLQLSAADRFVNFDSGDVLLNDGGGVSICLD
ARDLKGVAIAARNLAADIRKVCGAEAVVGTDERAGILIGTLGHSATIDRLVKRRLLDGGL
LRGRREKYIITLVGRQLVIAGSDRRGTIYGIYELSRQMGVSPWYDWADVPVARHDRIYIS
RGIYTDGEPAVRYRGLFLNDEAPCLTSWVKHTYGTGYGDHRFYARVFELILRLKGNMLWP
AMWGWAFYADDPENSRTADEMGVIMGTSHHEPMARNHQEWARRRKDYGAWNYQTNRTVLD
RFFREGIERMNGTEDIVTIGMRGDGDEAMSEEADTRLMQRIVENQRRIIADVTRRPAKET
PQVWALYKEVLDYYDKGMRVPDDVTMLLCDDNWGNVRRVPAAKERNRAGGWGLYYHVDYV
GAPRNSKWLNVTPTQNMWEQLQLAYNYGIDRLWILNVGDLKPMEYPISLFMDMAWNPRRY
DAATLTDHTLGFCREQFGEEQAPEAARILNLVGKYNGRITAEMLDASTYNVATGEWRRVA
DDYMRLEAEALRQYLSLRPEQRDAYRELVLFPLQAMSNVYQMYYAQAMNHFLYERNDPDA
NLWADHVAEAFRRDSLLCAAYNHDIAGGKWNGMMTQKHIGYTSWNDDFPRDKMPEVHRVE
TDGRPGGFVFEARDSVVAMEAEHFFACLPSSGARWTVIPYMGRTRSGLTLMPNTAPVAGA
SLSYRFSLGALRPSEVNVRVMVKSTLDFLNRGGLRYTVSLDGGQEREVNFNARLNERKEN
IYTVYYPTVARRVVESVVTLPVPPSPDGYHTLTIRPLDPAIVFEKVLVDAGGYKPGYLMM
EESPCRR

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	49	826	6.4e-274	0.9899569583931134

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	187	523	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	5.20e-42	667	842	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	0.007	67	154	33	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCS85271.1	0.0	17	843	3	828
CCG34758.1	0.0	47	843	1	798
AGB29053.1	0.0	35	844	28	832
QNT66545.1	0.0	27	834	16	846
QCD34650.1	0.0	48	847	39	846

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	30	847	25	853	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	48	847	19	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	48	847	18	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	2.39e-174	43	742	2	716	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	3.07e-111	64	647	29	648	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.009082	0.990122	0.000222	0.000185	0.000169	0.000167

TMHMM  Annotations     

start	end
13	35