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CAZyme Information: MGYG000001299_02143

You are here: Home > Sequence: MGYG000001299_02143

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Amedibacillus dolichus
Lineage Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelotrichaceae; Amedibacillus; Amedibacillus dolichus
CAZyme ID MGYG000001299_02143
CAZy Family CBM32
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
2150 MGYG000001299_19|CGC1 240367.01 4.5373
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001299 2190453 Isolate not provided not provided
Gene Location Start: 38912;  End: 45364  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.50

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH89 254 908 5.9e-211 0.9728506787330317
CBM32 37 169 2.9e-16 0.9112903225806451

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam05089 NAGLU 4.91e-134 313 642 1 333
Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold.
pfam12972 NAGLU_C 6.14e-81 650 910 1 249
Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold.
pfam12971 NAGLU_N 2.37e-20 216 283 1 67
Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold.
pfam00754 F5_F8_type_C 9.23e-08 38 169 5 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
COG1511 YhgE 1.96e-06 1692 2132 95 527
Uncharacterized membrane protein YhgE, phage infection protein (PIP) family [Function unknown].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCT45696.1 0.0 1 1917 1 2007
AYE33274.1 0.0 30 2114 44 2134
QAS61445.1 0.0 30 2114 44 2134
AMN35090.1 0.0 30 1908 42 1931
ABG85709.1 0.0 51 1908 50 1922

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VC9_A 0.0 51 931 25 882
Family89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin [Clostridium perfringens],2VCA_A Family 89 glycoside hydrolase from Clostridium perfringens in complex with beta-N-acetyl-D-glucosamine [Clostridium perfringens],2VCB_A Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc [Clostridium perfringens],2VCC_A Family 89 Glycoside Hydrolase from Clostridium perfringens [Clostridium perfringens]
4A4A_A 0.0 16 931 13 905
CpGH89(E483Q, E601Q), from Clostridium perfringens, in complex with its substrate GlcNAc-alpha-1,4-galactose [Clostridium perfringens]
7MFK_A 0.0 51 931 33 890
ChainA, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124],7MFL_A Chain A, Alpha-N-acetylglucosaminidase family protein [Clostridium perfringens ATCC 13124]
4XWH_A 4.65e-84 218 877 9 665
Crystalstructure of the human N-acetyl-alpha-glucosaminidase [Homo sapiens]
4A3Z_A 8.74e-08 1242 1373 28 159
CpGH89CBM32-4(seleno-methionine labeled) produced by Clostridium perfringens [Clostridium perfringens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9FNA3 8.88e-86 236 915 64 794
Alpha-N-acetylglucosaminidase OS=Arabidopsis thaliana OX=3702 GN=NAGLU PE=2 SV=1
P54802 4.23e-83 218 877 32 688
Alpha-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=NAGLU PE=1 SV=2
A0A3R0A696 2.81e-06 1860 2123 750 1008
Alpha-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=blArafA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000206 0.999141 0.000167 0.000166 0.000155 0.000137

TMHMM  Annotations      download full data without filtering help

start end
2127 2144