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CAZyme Information: MGYG000001543_02131

You are here: Home > Sequence: MGYG000001543_02131

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Lachnoclostridium sp900078195
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium; Lachnoclostridium sp900078195
CAZyme ID MGYG000001543_02131
CAZy Family GH5
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
658 MGYG000001543_7|CGC6 74536.75 4.7672
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001543 4599950 Isolate not provided not provided
Gene Location Start: 525949;  End: 527925  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.4 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH5 65 344 3.3e-83 0.9927536231884058
CBM46 373 458 2.2e-25 0.9885057471264368

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam00150 Cellulase 2.36e-43 61 345 12 271
Cellulase (glycosyl hydrolase family 5).
pfam18448 CBM46 6.00e-29 463 562 2 102
Carbohydrate binding domain. Carbohydrate active enzymes (CAZYmes) that target recalcitrant polysaccharides are modular enzymes containing noncatalytic carbohydrate-binding modules (CBMs) that direct enzymes to their cognate substrate, thus potentiating catalysis. The structure of Bacillus halodurans endo-beta-1,4-glucanase B (Cel5B) reveals that CBM46 is tightly associated with the catalytic module and, dependent on the glucan presented to the enzyme, can contribute directly to substrate binding or play a targeting role in directing the enzyme to regions of the plant cell wall rich in the polysaccharide hydrolyzed by the enzyme. The CBM46 domain displays a classic beta-sandwich jelly roll fold. Against beta-1,3-1,4-glucans CBM46 domain participates in productive substrate binding and thus plays a direct role in the hydrolytic activity of the enzyme.
COG2730 BglC 2.50e-28 44 354 51 371
Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism].
pfam03442 CBM_X2 1.93e-14 373 458 2 83
Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.
PRK11198 PRK11198 2.73e-14 580 657 62 145
LysM domain/BON superfamily protein; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AUS96699.1 8.39e-259 4 549 4 550
BCN31364.1 1.54e-250 5 552 5 559
ADL52313.1 4.81e-240 5 562 5 566
BAV13065.1 4.81e-240 5 562 5 566
ACZ98603.1 7.11e-229 1 576 1 574

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4V2X_A 1.62e-164 12 562 33 581
ChainA, Endo-beta-1,4-glucanase (cellulase B) [Halalkalibacterium halodurans]
5XRC_A 3.58e-160 21 562 30 566
ATrimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_B A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_C A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10]
5E0C_A 4.22e-160 29 562 5 533
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
5E09_A 2.20e-154 29 562 5 533
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
4YZP_A 2.90e-74 22 541 9 532
Crystalstructure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis [Bacillus licheniformis],4YZT_A Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis complexed with cellotetraose [Bacillus licheniformis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P23550 2.85e-165 5 562 8 561
Endoglucanase B OS=Paenibacillus lautus OX=1401 GN=celB PE=3 SV=1
P23660 3.29e-46 44 347 34 335
Endoglucanase A OS=Ruminococcus albus OX=1264 GN=celA PE=1 SV=1
P28623 8.08e-46 44 343 50 339
Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2
P10477 1.66e-44 5 345 2 354
Cellulase/esterase CelE OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celE PE=1 SV=2
P28621 4.34e-44 25 343 31 341
Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000249 0.998988 0.000294 0.000167 0.000154 0.000140

TMHMM  Annotations      download full data without filtering help

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