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CAZyme Information: MGYG000002543_01161

You are here: Home > Sequence: MGYG000002543_01161

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Campylobacter_B ureolyticus
Lineage Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Campylobacteraceae; Campylobacter_B; Campylobacter_B ureolyticus
CAZyme ID MGYG000002543_01161
CAZy Family GT9
CAZyme Description ADP-heptose--LPS heptosyltransferase 2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
312 35521.74 10.0746
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002543 1665696 Isolate Ireland Europe
Gene Location Start: 26420;  End: 27358  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002543_01161.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 69 290 8.5e-51 0.9644444444444444

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03789 GT9_LPS_heptosyltransferase 8.30e-72 2 307 1 277
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0859 RfaF 2.08e-63 1 305 2 326
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
TIGR02195 heptsyl_trn_II 3.60e-46 2 307 1 331
lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
pfam01075 Glyco_transf_9 8.27e-38 79 288 13 244
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
PRK10916 PRK10916 6.57e-22 147 273 180 307
ADP-heptose--LPS heptosyltransferase RfaF.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIX86954.1 8.40e-233 1 312 1 312
AKT90951.1 1.14e-230 1 312 1 312
QOQ86767.1 4.83e-157 1 303 1 303
QKF65085.1 4.83e-157 1 303 1 303
AGZ82220.2 2.28e-143 1 307 1 307

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1PSW_A 1.85e-19 146 306 179 340
Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P45042 1.64e-20 1 307 1 342
ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1
P37692 1.54e-19 146 306 179 340
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1
P37421 3.94e-19 146 303 179 337
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1
Q57336 3.92e-10 1 265 1 294
Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999881 0.000158 0.000009 0.000000 0.000000 0.000004

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002543_01161.