CAZyme Information: MGYG000002694_01216

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UMGS1591
• CAZyme ID: MGYG000002694_01216
• CAZy Family: GH36
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
591		67776.43	5.0291

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002694	2309879	MAG	Canada	North America

• Gene Location: Start: 1915; End: 3690 Strand: +

Full Sequence      

MSDWLKQDGITVSSEMDGRASLSRMACPDHHGEELIFTFDWSAEDAAALDNPDIQIVWRE
PFCDMLYAWQPLCCTDKTQRITWNGPLFTKTAISAPVMGYYNDRDNNVLTCAASELKKDL
GWLFAIEEETGDLRCGFVIPLLPFGPVHHYTLRVLLIREPLPFHKALDQVRCWWEDTCDV
HLAAVPKAAREPMYSTWYDFHQVLSDKELEEECRRGAEIGLRSIIVDDGWQTEDTGRGYG
FCGDWEIAKSKFPDMKAHVARVHALGMKYLIWYTVPFIGIHAKNRARFEDKFLCMDGTNG
VLDPRYPEVREFLKNTYLTALKEWDLDGFKLDFIDWFSVRGRAEQKPGMDFLCVQDALDF
MMKDILATLRSVKPDILIEFRQAYIGPNMRQYGNMFRVGDCPNNFVKNRVGITDLRMLSG
QSAVHSDMLMWHPEESPENCAIQMENVIFGVLQLSVRLDQQSPEQLELIRFWIDFMEKNR
HILLDTPLIPENPQFLYPVLRAEDGRRTIIGRYATTASIALDASRFDDVTLVNATKQEET
VLRFTAGEGRYDVELLDYRGRTVGHTHVEAKADGTALIRIPAAGLAVFHRG

Enzyme Prediction     

No EC number prediction in MGYG000002694_01216.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH36	186	485	3.5e-31	0.4476744186046512

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14791	GH36	3.73e-65	189	478	1	299	glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
pfam02065	Melibiase	1.64e-10	196	484	51	345	Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.
cd06592	GH31_NET37	1.10e-08	190	333	1	151	glucosidase NET37. NET37 (also known as KIAA1161) is a human lamina-associated nuclear envelope transmembrane protein. A member of the glycosyl hydrolase family 31 (GH31) , it has been shown to be required for myogenic differentiation of C2C12 cells. Related proteins are found in eukaryotes and prokaryotes. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.
cd14792	GH27	3.15e-08	192	400	2	179	glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
COG3345	GalA	1.35e-07	181	412	281	515	Alpha-galactosidase [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUO31288.1	3.86e-160	35	584	27	579
CQR57728.1	4.90e-152	52	585	49	584
QWG32884.1	5.37e-152	52	590	44	586
QWG44322.1	5.37e-152	52	590	44	586
QWH11404.1	1.07e-151	52	590	44	586

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000021	0.000005	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002694_01216.