logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003056_01832

You are here: Home > Sequence: MGYG000003056_01832

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Fusobacterium_A sp900543175
Lineage Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium_A; Fusobacterium_A sp900543175
CAZyme ID MGYG000003056_01832
CAZy Family PL8
CAZyme Description Xanthan lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
803 90980.51 5.7177
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003056 2294801 MAG United States North America
Gene Location Start: 172;  End: 2583  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003056_01832.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 423 678 6.2e-70 0.9884169884169884

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 7.73e-176 41 748 1 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam08124 Lyase_8_N 3.15e-75 49 382 1 323
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02278 Lyase_8 1.29e-73 422 674 1 249
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 4.95e-09 695 750 4 61
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AVQ18405.1 0.0 2 803 3 804
QNM15134.1 0.0 1 801 1 802
BBM36588.1 4.69e-266 37 803 20 787
AVL42971.1 7.27e-193 3 800 2 736
ACZ00618.1 7.27e-193 3 800 2 736

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2E22_A 4.21e-95 81 760 39 709
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 4.21e-95 81 760 39 709
ChainA, Xanthan lyase [Bacillus sp. GL1]
1J0M_A 2.21e-94 81 760 39 709
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
6F2P_A 3.48e-94 106 797 66 745
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
1X1H_A 5.98e-94 81 760 39 709
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 8.16e-93 81 760 64 734
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q59801 3.48e-80 41 781 48 798
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
Q54873 3.95e-79 84 717 329 960
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 5.22e-75 58 706 272 930
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
P0CZ01 2.11e-45 94 777 88 779
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000599 0.507347 0.491447 0.000210 0.000210 0.000173

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003056_01832.