CAZyme Information: MGYG000003128_00425

Basic Information

• Species: Corynebacterium simulans
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium simulans
• CAZyme ID: MGYG000003128_00425
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
389		40055.75	4.0959

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003128	1741617	MAG	United States	North America

• Gene Location: Start: 10155; End: 11324 Strand: -

Full Sequence      

MELCLSPMFSARTAAAAVLTLGLGFGLASCDSEQQESTQDPAASSSAPGAASASAAPSTT
PSEEAPVPVDRRQLAASVLMPPAVNYDDALAKLQAGAGGIFIPSWADPALLSEPERDINA
LRAAVGRDFQVSIDFEGGRVQRFSEILGEHPAPAQMAAEHSPEEVEQMGAEIGRVLKEHG
INVDFAPVLDVDGGELEVVGDRSFSTDPKLAGEYGAAFARGLESAGVKAVFKHFPGHGRA
SGDTHLGEAVTPPLEELYGHEFVPFQEAIPAAPAAGLMMGHLVVPGLGDGQTPASINPAA
YQLAREQLHYGGPIYTDDIGGMASIADTMNVPQAVVAALASGADMPLWSTDAEFPAAVDA
VVAALDDGTLTDAQLQASAQRLTGGKLPE

Enzyme Prediction     

No EC number prediction in MGYG000003128_00425.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	130	347	1.3e-44	0.9398148148148148

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	1.64e-62	79	353	12	284	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	6.89e-49	73	383	8	314	Glycosyl hydrolase family 3 N terminal domain.
PRK05337	PRK05337	7.26e-44	106	347	37	278	beta-hexosaminidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AMO92002.1	2.05e-258	1	389	1	388
AMO89379.1	2.04e-256	1	389	1	389
ATZ08787.1	9.79e-179	78	382	57	361
ATZ06875.1	5.64e-178	78	382	57	361
ART22347.1	1.14e-177	77	384	56	363

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5IOB_A	9.83e-97	65	382	22	343	Crystalstructure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_B Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_C Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_D Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_E Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_F Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_G Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_H Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032]
4YYF_A	2.56e-68	59	388	24	361	ChainA, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_B Chain B, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_C Chain C, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155]
6GFV_A	1.59e-63	98	388	46	339	Mtuberculosis LpqI [Mycobacterium tuberculosis H37Rv],6GFV_B M tuberculosis LpqI [Mycobacterium tuberculosis H37Rv]
5G1M_A	1.59e-29	116	351	64	297	Crystalstructure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G1M_B Crystal structure of NagZ from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1],5G2M_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G2M_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine [Pseudomonas aeruginosa PAO1],5G3R_A Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G3R_B Crystal Structure Of Nagz From Pseudomonas Aeruginosa In Complex With N-acetylglucosamine And L-ala-1,6-anhydromurnac [Pseudomonas aeruginosa PAO1],5G5K_A Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1],5G5K_B Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin [Pseudomonas aeruginosa PAO1]
6K5J_A	2.43e-28	98	382	44	333	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
L7N6B0	2.94e-62	98	388	89	382	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	8.19e-62	98	388	89	382	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1
B4SRK3	3.60e-35	120	347	46	276	Beta-hexosaminidase OS=Stenotrophomonas maltophilia (strain R551-3) OX=391008 GN=nagZ PE=3 SV=1
B2FPW9	9.69e-35	120	347	46	276	Beta-hexosaminidase OS=Stenotrophomonas maltophilia (strain K279a) OX=522373 GN=nagZ PE=3 SV=1
Q3SKU2	2.18e-34	98	366	29	297	Beta-hexosaminidase OS=Thiobacillus denitrificans (strain ATCC 25259) OX=292415 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000015	0.002105	0.997892	0.000002	0.000009	0.000002

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003128_00425.