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CAZyme Information: MGYG000004296_00419
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Ruminococcus_A faecicola | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Ruminococcus_A; Ruminococcus_A faecicola | |||||||||||
| CAZyme ID | MGYG000004296_00419 | |||||||||||
| CAZy Family | GH27 | |||||||||||
| CAZyme Description | Alpha-galactosidase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 19230; End: 20441 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH27 | 119 | 372 | 3.3e-65 | 0.9694323144104804 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd14792 | GH27 | 7.34e-136 | 25 | 302 | 1 | 271 | glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. |
| PLN02808 | PLN02808 | 1.34e-101 | 10 | 364 | 17 | 351 | alpha-galactosidase |
| pfam16499 | Melibiase_2 | 2.20e-100 | 24 | 302 | 1 | 284 | Alpha galactosidase A. |
| PLN02229 | PLN02229 | 1.31e-92 | 16 | 393 | 54 | 412 | alpha-galactosidase |
| PLN02692 | PLN02692 | 2.69e-90 | 15 | 393 | 46 | 403 | alpha-galactosidase |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QGG55641.1 | 1.90e-223 | 18 | 401 | 4 | 387 |
| QOS76902.1 | 4.30e-222 | 18 | 402 | 4 | 387 |
| QZN77867.1 | 8.68e-222 | 18 | 402 | 4 | 387 |
| APO43919.1 | 1.23e-221 | 18 | 402 | 4 | 387 |
| APC40140.1 | 2.48e-221 | 21 | 402 | 6 | 387 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UAS_A | 1.02e-86 | 21 | 393 | 5 | 354 | ChainA, alpha-galactosidase [Oryza sativa] |
| 6F4C_B | 8.37e-86 | 17 | 393 | 1 | 355 | Nicotianabenthamiana alpha-galactosidase [Nicotiana benthamiana] |
| 4NZJ_A | 1.44e-85 | 16 | 351 | 91 | 429 | Crystalstructure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343] |
| 4OGZ_A | 5.65e-84 | 21 | 379 | 96 | 453 | Crystalstructure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343] |
| 3A5V_A | 1.05e-73 | 18 | 392 | 2 | 384 | Crystalstructure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P14749 | 4.35e-89 | 21 | 393 | 52 | 402 | Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1 |
| Q8RX86 | 6.22e-88 | 17 | 393 | 32 | 386 | Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1 |
| Q8VXZ7 | 2.93e-87 | 16 | 393 | 64 | 422 | Alpha-galactosidase 3 OS=Arabidopsis thaliana OX=3702 GN=AGAL3 PE=1 SV=1 |
| Q42656 | 1.28e-85 | 21 | 365 | 20 | 344 | Alpha-galactosidase OS=Coffea arabica OX=13443 PE=1 SV=1 |
| Q55B10 | 2.24e-85 | 15 | 396 | 18 | 379 | Probable alpha-galactosidase OS=Dictyostelium discoideum OX=44689 GN=melA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999917 | 0.000129 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |