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CAZyme Information: MGYG000004708_00425

You are here: Home > Sequence: MGYG000004708_00425

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella;
CAZyme ID MGYG000004708_00425
CAZy Family PL6
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
721 MGYG000004708_20|CGC1 78727.36 7.3383
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004708 1820911 MAG China Asia
Gene Location Start: 13180;  End: 15345  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.11 4.2.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL6 33 395 3.2e-118 0.9704301075268817
PL6 451 650 3.4e-38 0.5821325648414986

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14251 PL-6 2.73e-153 34 395 6 367
Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.
pfam14592 Chondroitinas_B 4.30e-110 33 415 5 403
Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate.
pfam13229 Beta_helix 3.17e-06 505 651 26 139
Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
pfam13229 Beta_helix 1.08e-05 540 719 4 157
Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
pfam13229 Beta_helix 4.70e-04 217 344 29 139
Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIU93442.1 4.87e-281 4 717 3 723
QUT26279.1 1.71e-279 4 717 3 723
QNL39961.1 2.60e-272 19 717 18 723
QNT66846.1 1.04e-259 1 708 1 706
QRQ49286.1 1.94e-203 32 708 27 710

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7DMK_A 1.82e-208 28 708 13 700
ChainA, BcAlyPL6 [Bacteroides clarus],7DMK_B Chain B, BcAlyPL6 [Bacteroides clarus],7DMK_C Chain C, BcAlyPL6 [Bacteroides clarus],7DMK_D Chain D, BcAlyPL6 [Bacteroides clarus]
7O7T_A 2.67e-120 32 711 7 710
ChainA, Poly(Beta-D-mannuronate) lyase [Pseudoalteromonas atlantica T6c]
7O77_A 2.67e-120 32 711 7 710
ChainA, Poly(Beta-D-mannuronate) lyase [Pseudoalteromonas atlantica T6c]
5GKD_A 1.31e-118 38 654 14 653
Structureof PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_B Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_C Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis],5GKD_D Structure of PL6 family alginate lyase AlyGC [Paraglaciecola chathamensis]
5GKQ_A 1.01e-117 38 654 14 653
Structureof PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6],5GKQ_B Structure of PL6 family alginate lyase AlyGC mutant-R241A [Paraglaciecola chathamensis S18K6]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q06365 1.87e-66 44 405 2 354
Alginate lyase OS=Pseudomonas sp. (strain OS-ALG-9) OX=86038 GN=aly PE=3 SV=1
Q46079 8.33e-32 30 341 28 349
Chondroitinase-B OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=cslB PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000246 0.999116 0.000165 0.000167 0.000149 0.000137

TMHMM  Annotations      download full data without filtering help

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