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CAZyme Information: MGYG000004891_01844

You are here: Home > Sequence: MGYG000004891_01844

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; KM106-2;
CAZyme ID MGYG000004891_01844
CAZy Family GH5
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
864 95805.47 10.4949
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004891 3652874 MAG China Asia
Gene Location Start: 23424;  End: 26018  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004891_01844.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH5 89 378 6.3e-77 0.9891304347826086
CBM46 413 504 7.4e-24 0.9655172413793104

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam00150 Cellulase 3.26e-44 74 379 1 270
Cellulase (glycosyl hydrolase family 5).
COG2730 BglC 1.61e-24 57 378 47 360
Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism].
pfam03442 CBM_X2 1.17e-11 415 500 4 79
Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.
pfam18448 CBM46 5.57e-09 530 612 21 102
Carbohydrate binding domain. Carbohydrate active enzymes (CAZYmes) that target recalcitrant polysaccharides are modular enzymes containing noncatalytic carbohydrate-binding modules (CBMs) that direct enzymes to their cognate substrate, thus potentiating catalysis. The structure of Bacillus halodurans endo-beta-1,4-glucanase B (Cel5B) reveals that CBM46 is tightly associated with the catalytic module and, dependent on the glucan presented to the enzyme, can contribute directly to substrate binding or play a targeting role in directing the enzyme to regions of the plant cell wall rich in the polysaccharide hydrolyzed by the enzyme. The CBM46 domain displays a classic beta-sandwich jelly roll fold. Against beta-1,3-1,4-glucans CBM46 domain participates in productive substrate binding and thus plays a direct role in the hydrolytic activity of the enzyme.
COG5492 YjdB 8.63e-07 619 766 184 318
Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction only].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ABX43556.1 1.37e-177 54 614 39 587
QTL80832.1 7.57e-135 48 606 250 801
QTL78854.1 2.09e-134 48 606 250 801
ADB10706.1 4.59e-134 48 606 254 805
VEG24685.1 4.59e-134 48 606 254 805

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5E0C_A 1.27e-97 49 613 5 534
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
5XRC_A 4.78e-97 49 613 38 567
ATrimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_B A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_C A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10]
4V2X_A 5.04e-95 55 624 59 593
ChainA, Endo-beta-1,4-glucanase (cellulase B) [Halalkalibacterium halodurans]
5E09_A 2.08e-93 49 613 5 534
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
4YZP_A 6.62e-61 58 562 28 494
Crystalstructure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis [Bacillus licheniformis],4YZT_A Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis complexed with cellotetraose [Bacillus licheniformis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P23550 1.32e-100 49 612 32 561
Endoglucanase B OS=Paenibacillus lautus OX=1401 GN=celB PE=3 SV=1
P28623 1.19e-46 17 385 11 346
Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2
P28621 5.87e-46 8 378 3 341
Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1
P54937 1.93e-45 49 404 34 371
Endoglucanase A OS=Clostridium longisporum OX=1523 GN=celA PE=1 SV=1
O08342 2.52e-44 52 378 39 369
Endoglucanase A OS=Paenibacillus barcinonensis OX=198119 GN=celA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000495 0.998659 0.000245 0.000230 0.000179 0.000156

TMHMM  Annotations      download full data without filtering help

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