| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra017918 |
| Family | GT47 |
| Protein Properties | Length: 458 Molecular Weight: 52212.7 Isoelectric Point: 9.2766 |
| Chromosome | Chromosome/Scaffold: 06 Start: 8828190 End: 8830379 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 82 | 380 | 0 |
| LSLKIYVYDENEIDGLKELMYGRDGGVKTASCLKGQWGSQVKIHKLLMESKFRTSKKEEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWSTFINHSIILTPEGDRTDKKDTTAFNTWKDIIIPGNVDDAMTRNGQPDVQPLPLSKRKYLANYLGRAQGKAGRLKLIDL SKQYPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSSRIGAELLDYLASI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 458 Download |
| MASLSSKPRN FGAYSSHYAT PCTRTHQIGA LFLVVSTFFL TRLFDQWYSV SPAIDLHRTD 60 SSVTTSDNGA LRWPERGYGS HLSLKIYVYD ENEIDGLKEL MYGRDGGVKT ASCLKGQWGS 120 QVKIHKLLME SKFRTSKKEE ADLFFVPAYV KCVRMLGGLN DKEINQTYVK VLSQMPYFRR 180 SGGRDHIFVF PSGAGAHLFR SWSTFINHSI ILTPEGDRTD KKDTTAFNTW KDIIIPGNVD 240 DAMTRNGQPD VQPLPLSKRK YLANYLGRAQ GKAGRLKLID LSKQYPDKLE CPDLKFSGTE 300 KFGRTTYFEH LRNAKFCLAP RGESSWTLRF YESFFVECVP VLLSDHAELP FQNVIDYAQV 360 SIKWPSSRIG AELLDYLASI PDRDIEEMIS RGSKIRCLFV YGPDYAPCSA VKGILWELQR 420 KVRHFQQSTE TFWLHNGSFV NRELVHFSSW RPPMPLP* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-44 | 84 | 380 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF87908.1 | 0 | 1 | 457 | 1 | 414 | AC015447_18 Hypothetical protein [Arabidopsis thaliana] |
| GenBank | AAL75891.1 | 0 | 1 | 457 | 1 | 462 | At1g21480/F24J8_23 [Arabidopsis thaliana] |
| GenBank | AAM61682.1 | 0 | 1 | 457 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 457 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002300942.1 | 0 | 1 | 457 | 1 | 460 | predicted protein [Populus trichocarpa] |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| BX841155 | 336 | 1 | 330 | 0 |
| EX093096 | 282 | 1 | 282 | 0 |
| CX668832 | 291 | 144 | 434 | 0 |
| EX118394 | 232 | 227 | 458 | 0 |
| CD825121 | 244 | 152 | 395 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
| Phylogeny |
|---|
 |