Results - Acr-Aca DB

Anti-CRISPR Results - GCF_000006785.2 (Total 4 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	Self Target Outside 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268900.1	532500	532730	+	77	3	9.8356	WP_000272856.1\|HTH_XRE-3-AcrIIA15\|45.3\|4.9e-12	0.157684093	686	-4.6239157	145	-4.6239157	PHAGE_Lactoc_98201_NC_031064-gi\|100005\|ref\|YP_009286319.1\|\|1.62e-29	-	MTINLKRLKAERIASGMTQCEVAQSMGWKTRTPYAKRENGIVSIGADELAKITLIFGLPIEKIAIFFDKDVPVMER	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268901.1	532799	532936	+	46	1.5	7.8268	Acr	0.369312067	107	-2.5504696	40	-2.5504696	PHAGE_Strept_phiARI0004_NC_031920-gi\|100042\|ref\|YP_009322371.1\|\|4.71e-04	-	MKNKKEQWTPKVHCFRKDGSQCEPENITVPISFAGYYQILLELGV	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268902.1	532938	533063	+	42	7	10.5956	Acr	0.276588262	443	-4.1519527	110	-4.1519527	PHAGE_Strept_T12_NC_028700-gi\|966201493\|ref\|YP_009191681.1\|\|1.01e-16	-	MKLLDFIFTKPKKQEPIKHDTKRLSSEKQYDAFHAYMRKKV	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268903.1	533060	533287	+	76	-4.5	4.4217	Acr	0.704874659	72	-2.115981	31	-2.115981	-	-	MKQQLINDNEFLRDENRRLNNELAEHYFVVTAKANLLDVIIASDFILKSTLDKCIAELDEIDQIALLKAWNKGEL	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268912.1	542330	542548	+	73	-1.5	5.0929	Acr	0.260103619	102	-2.4816341	38	-2.4816341	PHAGE_Strept_phiARI0468_4_NC_031915-gi\|100032\|ref\|YP_009322114.1\|\|2.46e-25	-	MEIYKQRMIEEYKQLKKRAEKLSIVLNRYYLDELDFELSCPIELLQTQWHIMGAYLKILEQRFLVEGIYFND	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268913.1	542541	542936	+	132	2.5	8.0386	AcrIIA9-3-WP_011965783.1\|HTH_34\|41.0\|0.00044	0.070214323	133	-2.7822547	47	-2.7822547	PHAGE_Bacill_BCJA1c_NC_006557-gi\|56694892\|ref\|YP_164402.1\|\|2.99e-59	-	MIEFFLPMDKIPTTTHQQKKVTVINGKPHFYEPESLKNARDKFTSLLAQHVPPSKLDGPIRLTVKWLFPKIKGSTNGQYKTTKPDTDNLQKLLKDCMTELGFWNDDAQVASEIIEKFWADTVGIYVKVEEL	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_268914.1	542933	543154	+	74	-5.5	4.1429	Acr	0.707967473	4	-0.49883592	1	-0.49883592	PHAGE_Bacill_BCJA1c_NC_006557-gi\|56694893\|ref\|YP_164403.1\|\|9.89e-06	-	MKIDYINFFEQVVPDWMRESNVKMQEVGFNTEAYWQWANQSIVAICEKYGNDSLINGQFHLIWEWLEDKANGG	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_269156.1	794178	794639	+	154	7	10.6251	Acr	0.366317198	855	-4.8781233	Not found in Prophage	Not found in Prophage	-	-	MKKGRFKRNWPIILFGIIVFIFSFYFKISPKSLKNFTDIMSASLSFSAIVTAIFFASFSLIPTSGSNKLVVMMEDLGTEIKIMDRLLVATFLSFISSLLSFISLFFSKTDTDLISILVVSSWLSSTVMMFLSSFFVLRTLILLVETYNNFKNK	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_269157.1	794667	795149	+	161	-3.5	5.1629	AcrIIA7-0-WP_050431000.1\|HTH_23\|39.3\|0.00019	0.068271007	23	-1.1374247	Not found in Prophage	Not found in Prophage	PHAGE_Staphy_phiETA2_NC_008798-gi\|122891755\|ref\|YP_001004301.1\|\|2.08e-22	-	MDWRWWKIAYEELTEKQQRFVDKYITTFNATESAKQAGYSEKSAYSQGQRLLKNVEIQKAMKERFLEAKDTKGDRIQDVAETLEQDTSIARGEIQISEFKETDMLTGQVVIHTKREYTPSHEEQGRARDRIYKVNGAYSEKRELEHSGTVVFANEDNIPD	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_269911.1	1610257	1610463	-	69	0	6.2006	WP_060665735.1\|HTH_3\|AcrIIA1\|65.1\|4.5e-21	0.149128906	199	-3.227825	62	-3.227825	PHAGE_Brevib_Abouo_NC_029029-gi\|971767218\|ref\|YP_009220108.1\|\|1.02e-10	-	MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTINLCIAICRVLDKTLDDLFWEADDSR	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes M1 GAS	NC_002737.2	NP_269912.1	1610460	1610999	-	180	7.5	9.9668	Acr	0.359153448	1689	-5.960142	247	-5.960142	-	-	MSYKDLKEKRIMFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGGVAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYTIGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHYLDAKEADE	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_000006785.2	NC_002737	NC_002737_1[860819;861250] (evidence-level=4), NC_002737_2[1055475;1055576] (evidence-level=1), NC_002737_3[1123120;1123255] (evidence-level=1), NC_002737_4[1283502;1283730] (evidence-level=1), NC_002737_5[1684700;1684833] (evidence-level=1),	5	Nb_arrays_evidence-level_1=4,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=1	CAS-TypeIIA[854751;860716], CAS-TypeIC[1283879;1291892],	2	CAS-TypeIC (n=1), CAS-TypeIIA (n=1),