Results - Acr-Aca DB

Anti-CRISPR Results - GCF_000723465.1 (Total 10 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038670741.1	531065	531277	-	71	2.5	9.2972	Acr	0.522003411	41	-0.39284253	Not found in Prophage	Not found in Prophage	-	-	MYYNEKRKAITAKYVKTHLDDIKIRVPKGQREKLKAIASEMGMSMNQMFIKAVEEYIEKNYKPEAESETD	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 1	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038670739.1	530530	530967	-	146	-2.5	5.0881	AcrIIA1-1-WP_029148690.1\|HTH_IclR\|43.6\|0.0066	0.124416296	288	-2.3089325	Not found in Prophage	Not found in Prophage	-	-	MEMNGGFLVTKIKQLGDRIFEKILSEKNIDAFNGAQGRILYVLWQEDGISIRSLSTKCGLAITSLTTMLERMENQGLISRVQSETDKRKTLLFLTEKAHALKGEYDSVSDEMGSVYYKGFSEEEITRFEECLDRIRKNLEEWQKS	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 2	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038670754.1	537763	538317	+	185	-2.5	5.333	WP_000690626.1\|HTH_7-3-AcrIIA14\|33.6\|4e-09	0.073710251	320	-2.4119205	Not found in Prophage	Not found in Prophage	PHAGE_Clostr_phiCTC2B_NC_030951-gi\|100001\|ref\|YP_009277342.1\|\|4.02e-14	-	MYTTLKQERNRQRTVVFYGRVSTEHEAQISALDNQLQWYDNQAKQHNNWNVIDKYIDEGITGTQTKKIPSFLQMIEDARQGKFDLIVTREVCRFARNTVDTLTFTRELKNLGIEVYFVEDDIWTMDGDGELRLTLMATLAQDESRKISERVHAGQYISRENGVLYGNGNILGYDRVGSTYVINP	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 2	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038670756.1	538395	538661	+	89	3	8.2884	Acr	0.366952723	733	-3.4348242	Not found in Prophage	Not found in Prophage	-	-	MVSRITPVDNTNFEWIINLGEEKSEKIRCTLTGRKNSAEFTIGDGESCHFTYWLINLLGLNGEIVIKSRAGELLLRLLLHRRSNSCKV	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 3	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672013.1	1574654	1575103	-	150	5	8.9118	Acr	0.216934228	2580	-5.7764864	Not found in Prophage	Not found in Prophage	-	-	MEFVIIATVVLVLAMCLGADFVIVPIMFIVFLVVLLLVIFGFFVYSAVKLTGTKSVKGKFVRFGRAEGKKFDTAFYKVNDSEYPNVFPCEVVMRSKIYIPDKVCRLRYDGKRNEVFDLNAVCCVIFGLILSSISAVMMILFLLTVIGIN	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 3	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672016.1	1575113	1575649	-	179	-6	4.6633	AcrIF10-0-WP_101570528.1\|HTH_19\|35.7\|2.6e-05	0.055466907	333	-2.4567358	Not found in Prophage	Not found in Prophage	PHAGE_Bacill_phi105_NC_004167-gi\|22855027\|ref\|NP_690787.1\|\|1.48e-05	-	MEKNTLGKRIKEARLAKKMTQSEVVGDFITRNMLSQIESGSATPSVKTLEYLCKVLEIEPNALLPDENDSKNAPDAEGYISIRKEFINKNYKAVIEYDADDEFSDEICALKAKACLMEAMEYSGSDSATDLQKAIDLAKQASELSKCGVFADESVKNKADELLKANAKRLSDYYRSLL	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 4	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672082.1	1637337	1637684	+	116	0.5	6.9335	Minot_Diet_SRR5088940_NODE_81_length_37086_cov_37.905485_54\|HTH_3\|AcrIIA1\|31.9\|3.8e-10	0.140380527	202	-1.8878198	Not found in Prophage	Not found in Prophage	PHAGE_Entero_phiFL3A_NC_013648-gi\|281416228\|ref\|YP_003347577.1\|\|2.44e-07	-	MTEMYKRIKELCEENHMTVSQMCKELSITRSCLSELSKGRTERLSAENSTKIANRFGVSVQYLISGREEDFDTKLKYALFNGTLGVTDEMFDEVKQYAEMVMLREEAKRRKAGEK	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 4	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_022287877.1	1637688	1638092	+	135	0	6.4646	Acr	0.201512367	626	-3.185712	Not found in Prophage	Not found in Prophage	PHAGE_Clostr_phi3626_NC_003524-gi\|20065986\|ref\|NP_612852.1\|\|1.42e-07	-	MTNIQELYDICSRENITIDFIDCPKCGAISLFGAGGCAIGIDSQTPARLLKERTAHEIGHCVKGAFYNRYATADNISQHEYRADKWAIENLIPKSELIKAIKKNLDSIYLLAQHFDVSEDFMIKACRYYGVYFG	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 5	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672125.1	1688876	1689274	-	133	-3.5	4.9245	Acr	0.584364086	618	-3.1781144	Not found in Prophage	Not found in Prophage	-	-	MSEMIEFSIYGTQDNFCDDFQEINEQLAPYNARFVMPSGLGAGIPIDSIIHIFLPFVTEAFKTFVLNGGYDIFKMRISKLYAKFTKHAKEKNMNCVVYISRAKGPDYNKIKIENPTEEVLLHTIDRFFDDDV	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 5	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672127.1	1689420	1689593	-	58	5	10.3186	AcrIIA7-3-3300001356_____JGI12269J14319_10000030_160\|HTH_17\|37.5\|6.3e-09	0.192318614	528	-2.9952424	Not found in Prophage	Not found in Prophage	PHAGE_Gordon_GordDuk1_NC_029060-gi\|985757552\|ref\|YP_009222511.1\|\|7.17e-07	-	MFDDIPDILTAKECQQLLKIGKNSMLRYLKTGEIEGFKIGSRWRIYKFSVIEFLRKR	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 6	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672243.1	1759867	1760103	-	79	3	9.7159	AcrIIA7-2-3300015241_____Ga0137418_10000051_76\|HTH_38\|36.1\|0.0059	0.280494335	472	-2.8679128	37	-2.8679128	PHAGE_Paenib_PG1_NC_021558-gi\|514231213\|ref\|YP_008129891.1\|\|2.84e-11	-	MYKTYRNLEAELSRYGIARKDIAAVLGLNVNTVSEKLSNPDRLKLKEAQTIRRTFFPKLTMEYLFDDGELSGKYQREA	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 6	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672244.1	1760135	1760338	-	68	4	9.9261	WP_132356487.1\|HTH_3\|AcrIIA15\|30.2\|0.00064	0.271662718	612	-3.1708453	48	-3.1708453	PHAGE_Brocho_NF5_NC_015252-gi\|327197614\|ref\|YP_004301305.1\|\|0.006	-	MLTIIGKNVKRIINERNIKQKDAAALCGYSAKTFSNMLNGYLTIRDTDIVKIKRGLDVEYNELFLSA	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 6	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672241.1	1759591	1759827	-	79	-4	4.8447	Acr	0.794022168	205	-1.893583	Not found in Prophage	Not found in Prophage	-	-	MIKLTIEISEHTTDELKPHYDRFNAIETAAGREPHTFEEYLEMVLTLGCHGFMIRNADRLESSLKAYYKQTGGDKIDE	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 7	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_022287119.1	1790894	1791259	-	122	-2.5	5.609	AcrIIA14-0-WP_057707492.1\|HTH_5\|38.0\|1.3e-18	0.131252069	87	-1.077598	Not found in Prophage	Not found in Prophage	-	-	MSENTVKHEHKQCGGKNIEKMEEIGKTMPVEEEIYDVAELFKVLGDQTRVKILFTLIKDEMCVCDIAELLEMSQSAISHQLRVLKQARLVKYRREGKTVYYSVSDEHVAVILNMGIEHISE	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 7	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_038672281.1	1791363	1791584	-	74	8.5	10.2853	Acr	0.269248233	1002	-3.8854246	Not found in Prophage	Not found in Prophage	-	-	MRWKISWHPHAAGTDRGNPRDAGERHACQITIALKAVLRDQDGFLLYYRHFYDTRVHCLRKMQKNFQNPLDKT	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 7	Medium Confidence	Ruminococcus bicirculans	NZ_HF545616.1	WP_051706681.1	1791619	1792011	-	131	2	7.3161	Acr	0.404722414	22	-0.08067089	Not found in Prophage	Not found in Prophage	-	-	MAVNKVYSVGKIDIEIYKCVTEDIQTDEVIITERQIEHIKERHPSDYERYFSYAQEIIREPDYILEANKPNTAFVLKHIVDNGKNYQLILRLKTSHDPADYCNSIITFLKVEEKRYNRYLRTKKILYKSE	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 8	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_022288297.1	170141	170584	+	148	6	9.94	AcrIF2-1-WP_026236093.1\|HTH_34\|31.6\|6.1e-05	0.115714916	1313	-4.3357987	Not found in Prophage	Not found in Prophage	PHAGE_Brevib_Jenst_NC_028805-gi\|971744989\|ref\|YP_009199208.1\|\|0.007	-	MVDNVRRECIMSMYEIYPLSRKLVFDTFDKKKYDITRTQQIIMLSLCIEGTLTMSQLASKINTSNEQATRAVAQLVDKGFVIRMQNPDNRRVINIRLTDEAMRFMEKMKNEILDDILGKFSSVSDSDMKKMKDALVFINSILKKVLK	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 8	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_022288298.1	170594	170788	+	65	-7	4.0812	Acr	0.285836484	102	-1.1807382	Not found in Prophage	Not found in Prophage	-	-	MTKAKKIVSRCESCVNYVFDEDCECYCCMVDLDEDEAYRSMSDSEYSCPYYRLDDEYAVVRKQN	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 9	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_022287501.1	313658	313864	-	69	0	6.341	WP_066083800.1\|HTH_3\|AcrIIA1\|67.2\|5e-20	0.147649091	1360	-4.3909698	Not found in Prophage	Not found in Prophage	PHAGE_Bacill_1_NC_009737-gi\|158348425\|ref\|YP_001522916.1\|\|5.58e-09	-	MPELKTKLKEYRAKLDMKQGDLAEKVGVRRETIIRLEKGQYNPSLKLAMDIAKVFGVSVEDIFSFEDE	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 9	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_041337332.1	313864	314331	-	156	1.5	6.98	Acr	0.520321198	48	-0.57939065	Not found in Prophage	Not found in Prophage	-	-	MKAKKEKKKITLREYHKKRMVTGIAILVTEIFENTAEHYKLDNTTWATVIFVVLAAMTALFAVIWLYASCQKVDKEDEMAKENMLKAHQSITKMFLIILAVAIFISMFWEGSITIKINSDRLYQVWFIFWFSYMTLESGFFLHHEGKLSTDEEDE	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 9	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_041337334.1	314342	314824	-	161	2.5	8.2238	Acr	0.378851021	1481	-4.539759	Not found in Prophage	Not found in Prophage	-	-	MNDKTEIKTDKISYKKYYRQMGILGTLGGAMWIFYWVMEKVLPAIKKGHTLTNVINLIVSLGTLALIAICITKMISTVGKRDTNDELTQQTTAKVNQTFITFLFTIACLFISVMTLFSDILGRFKVTLNEYVITGLIWFCYAVYNFIGLYFESKFDDDEN	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 10	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_081856066.1	568758	569321	-	188	1	7.1665	WP_098798136.1\|HTH_Mga-0-AcrIIA1\|31.1\|1.1e-14	0.117186582	443	-2.781669	Not found in Prophage	Not found in Prophage	PHAGE_Sinorh_phiM9_NC_028676-gi\|966199376\|ref\|YP_009189470.1\|\|4.43e-04	-	MQSNGLYIRVIDERLFKTTKEVTALTRDIDYIVDKFSDDIYRAALAVTGSVHEAEDIVSEVIIKYFTRQGELFFNDDEHLKAWLLRTAINLSKDLLRSAGRRLRAENEVSARSDFSSPDMQIDVQNAINRLDKKYRIVLYLFYYQGCKTDEIADILGTSKGTVTSRLKRAREKLKLSLSDYEKEMSV	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans
Acr-Aca 10	Medium Confidence	Ruminococcus bicirculans	NZ_HF545617.1	WP_041337507.1	569360	569854	-	165	4.5	8.6269	Acr	0.594997307	601	-3.1492774	Not found in Prophage	Not found in Prophage	-	-	MSEQINPIVSEKDMGTDGKLRKWSTGRKAKWIIWIVIILAVALGFWHQHYMRSDSQIKAVFNDNKTNFQTTAEFMIESISCEKPTLPKGKCSIKSLTENNACKSVKKELEELERRNVTYIDSDGLTVKFYTIYDHYYIYRSPISSSGGEDNLGDGWSYVKTSKS	No	Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus; Ruminococcus bicirculans

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_000723465.1	NZ_HF545617	NZ_HF545617_1[253727;262985] (evidence-level=4), NZ_HF545617_2[263506;263603] (evidence-level=1), NZ_HF545617_3[263849;263947] (evidence-level=1), NZ_HF545617_4[526942;527175] (evidence-level=1),	4	Nb_arrays_evidence-level_1=3,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=1	CAS-TypeIC[245612;253567],	1	CAS-TypeIC (n=1),