Results - Acr-Aca DB

Anti-CRISPR Results - GCF_000963675.1 (Total 8 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	Self Target Outside 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249195.1	1070033	1070431	-	133	-7.5	4.2978	Acr	0.544831345	513	-3.8606262	133	-3.8606262	-	-	MIVKLKLGAVVVLSQVKQATIAYAGSEAYQTAIEQAKKGLLDEDKGKPFETVLHFPAVYADEDGQEEICPEQIATTVRSDNVSGEPVAVVLIPDDNVVGELQSIFIYKTDYAEIFTDNGVKLSAVRTSPAPR	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 1	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249194.1	1069409	1069885	-	159	-9	4.3936	AcrIIA7-2-WP_000349509.1\|HTH_30\|53.5\|2e-40	0.187968602	788	-4.3396654	195	-4.3396654	PHAGE_Entero_c_1_NC_019706-gi\|428781736\|ref\|YP_007111504.1\|\|8.17e-55	-	MDNLFDLKLNINQIAELTGLHRQTVSQRVAGLNPALGSNSKLKLYALRDLILTGLAEKMSADVDSLSPADRRAWFQSENERLKFEKEIGELIPASEVALEMSALAKTVVQALETLPDILERDCGLQPKDLIRVQQVTDDVRDQMALHIQEVTTDTENE	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 2	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006250080.1	1133985	1134191	+	69	0	6.1804	WP_055150624.1\|HTH_XRE\|AcrIIA1\|48.7\|3.5e-06	0.145068298	1028	-4.6471167	250	-4.6471167	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749643\|ref\|YP_009203423.1\|\|1.85e-44	-	MNKIAEIRNQIGISQAQLAVQIGWGQPRIANYETGNRTPSIYVAQKIVEGLNELGANVRIDDVFPVGN	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 2	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006253537.1	1134212	1134472	+	87	2	8.549	WP_142130479.1\|HTH_Tnp_ISL3\|AcrIIA1\|36.7\|0.0089	0.553262354	195	-2.8368797	58	-2.8368797	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749644\|ref\|YP_009203424.1\|\|1.86e-57	-	MPRNELTKNARAIADLIHRKSATVTHKKLARAIGLSESQFSRTFADNVEMVAVIIDYLSIELADKDELLELKEKRYKRINLEEATT	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 3	High Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249172.1	1168489	1169007	-	173	3	8.9234	AcrVA3-0-WP_077553360.1\|DUF1870\|68.4\|1.8e-39	0.225303573	764	-4.3002214	189	-4.3002214	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749619\|ref\|YP_009203399.1\|\|1.39e-126	-	MTTQVTPQIMRIIGQIVAATYGDDVPTNVQTIILRYPIRGIGFISSRRELSINNGEIARLMDKIPGDLEDPKDGMPFDCQGAFWLGYYQYCKLSNDVKNYTSKELSIIGESLYGTQWQSNLARDLRLSDARRVREWVAGERKIPFGVWADLTELVKAKKANLSSILKKLTID			Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 3	High Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249171.1	1169077	1169667	-	197	-1.5	5.3826	Acr	0.514313197	403	-3.6100926	108	-3.6100926	PHAGE_Mannhe_vB_MhS_1152AP2_NC_028956-gi\|971760512\|ref\|YP_009213787.1\|\|5.86e-144	-	MTTQITTAQINDLLKSHDIQGYANEWQGRRIYINLSAKNNESKGDRNYQLYIDLATGELVSKLGKGLTTRAFDAAVKAFENAFNAKDTAENTAPVESKETEQENKQETTKLVITKPTLKGSEKQIDSANEIINLFIAKIGDTSIPVTATQEQITQAQAMVDNFFAMTNAGKWIEKFKGLNDNSEPKQFWLSVKYGW			Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 4	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006253560.1	1471964	1472155	+	64	5	10.1414	AcrIIA13-0-WP_006662529.1\|HTH_17\|33.3\|2.7e-07	0.153687408	182	-2.7635581	Not found in Prophage	Not found in Prophage	PHAGE_Ralsto_RSY1_NC_025115-gi\|691326898\|ref\|YP_009067125.1\|\|2.66e-07	-	MTYSEQSYLNVKDVCEMLQLNRSTIYRQIKQGIFPKPTKIGKSSRWKFADIKAFLEPKPQEAN	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 4	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006250233.1	1472155	1472535	+	127	6.5	9.3767	Acr	0.267640322	605	-4.04282	Not found in Prophage	Not found in Prophage	-	-	MAGLSIICPFCGNTARIRGSSRPSLLSYQAQLTCSNCGQLKADFVGQLINIKRAVFIECDEANQWDKPENELIKEGKIQGKDNAQRLKELRGSQQDLFAKVPGQLPPEKITPAEKIAKRANLSKTH	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 4	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006250234.1	1472603	1472785	+	61	7	10.5311	Acr	0.26581145	2091	-5.5118656	Not found in Prophage	Not found in Prophage	-	-	MRKICKEIKAGLTISEGVRFFLKSLGIGLFLALFFYFLPYLAEFIIAVKKQLAKKSAYFQ	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 5	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006248632.1	2471688	2472008	+	107	1.5	7.7125	Acr	0.623413713	493	-3.8101459	126	-3.8101459	PHAGE_Mannhe_vB_MhM_3927AP2_NC_028766-gi\|971741506\|ref\|YP_009196054.1\|\|1.17e-65	-	MQKVYSEKAGEMMNPLNAFIHDSLVKLEIATLECEAMELEVERVEFEAKSPPRLVLRDNCKTQDLVKNGLASLFGMKTKGGRRYDSYQMQVRGVKCVWESERVTKV	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 5	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006248633.1	2472011	2472202	+	64	5.5	10.3923	WP_111526104.1\|HTH_26\|AcrIIA15\|54.5\|0.0088	0.258150627	71	-1.9538112	18	-1.9538112	PHAGE_Mannhe_vB_MhM_3927AP2_NC_028766-gi\|971741507\|ref\|YP_009196055.1\|\|2.72e-40	-	MKKRRMIYALYVGEENVADGTAEELAERLGVEAKTVRFMSSPAHNKRVKYNGKAIRTVKVGLE	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 6	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249610.1	2648117	2648647	-	177	7.5	9.8361	Acr	0.101998711	2233	-5.6222377	403	-5.6222377	PHAGE_Mannhe_vB_MhM_3927AP2_NC_028766-gi\|971741504\|ref\|YP_009196052.1\|\|2.60e-69	-	MSENSLKTHYSAKELAELSLACLPKTKQGVLYQAKKQGWTTHKKVGVGGEILEFALSNLPQEIQTEIRSRFMSAVVEAKPKKLPAVRAEVDVGNLTTKQREIADARMALVAYVLELEGSMSRIKAITYLCNLAKQGEMPPHLVELVAVANAKKTAKRTIVPIFSPIMPDFPLDSRD	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 6	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249609.1	2648663	2648926	-	88	7	10.4095	WP_005567622.1\|HTH_35-3-AcrIF9\|62.3\|1.1e-19	0.146408531	284	-3.2246957	82	-3.2246957	PHAGE_Haemop_SuMu_NC_019455-gi\|418489037\|ref\|YP_007002910.1\|\|1.25e-46	-	MSTLEDIKKTAKDWHRADIIAALHKAGWSLRQLSLKHGYSQSSTLKNAVDRPWLKGERIIAEAIGISPEEIWPERYAQRNHKKFADR	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 7	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249608.1	2649110	2649592	+	161	-0.5	6	AcrIIA7-3-WP_057903263.1\|HTH_3\|35.1\|0.0044	0.04722432	1334	-4.9468126	294	-4.9468126	PHAGE_Haemop_SuMu_NC_019455-gi\|418489036\|ref\|YP_007002909.1\|\|3.43e-11	-	MKIECKKVIGFGNRIEQSRKNAKLSRSEVCDALGGIAISTLQAWEADTREPPISKLMALSQILNVEPCYLLTGERHSQSLNVTREPQPVYATKPQTEEGEVVVIKAKLQEAIETLEEVLEITQREMKPAGKAQMVWAFYELLTQEKSEKEKMVGLLKLVA	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 7	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249607.1	2649604	2649855	+	84	-1	5.6002	Acr	0.373114555	107	-2.2405803	Not found in Prophage	Not found in Prophage	-	-	MDKQAILKLFRDNSTAGNSQPSQEPIQVFNNSNVIIQNGDNATVIAGCTVDNNTNLTCADKQRVHDLIHSLEQRNRASRDEGA	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 8	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249755.1	2665969	2666253	-	95	2.5	7.6418	Acr	0.128970463	356	-3.4659867	Not found in Prophage	Not found in Prophage	-	-	MRYWLISLSILLSGCVVPVTPTGQAGIPMPIIIGVSDPLDSKEVHICTLKPFTQEYRSEHSSRGRAKLNVQKQCRANHSEMFCEEKDIVCKTYD	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 8	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249756.1	2666283	2666468	-	62	9	10.1765	Acr	0.149426432	498	-3.8250227	Not found in Prophage	Not found in Prophage	-	-	MKCRQATELISQSCDEKLRLQQHMRLQLHLLVCPKCRNFNKNTKKLGKILRAYCNDKDAPF	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 8	Medium Confidence	Mannheimia haemolytica	NZ_CP011099.1	WP_006249757.1	2666465	2667031	-	189	2.5	7.0858	WP_095590313.1\|HTH_23-0-AcrIF6\|37.5\|1.3e-06	0.135199451	121	-2.3267798	Not found in Prophage	Not found in Prophage	PHAGE_Pseudo_PA11_NC_007808-gi\|149408171\|ref\|YP_001294605.1\|\|0.005	-	MKSLSSTQIEEIRKQMVKFATLQLADKDLAEDVVQDALTNAYKHSASFRREAALKTWIFAILKNKILDLLRTRKRHIPVSSLCEEEESPSAFFDRHDHWLEHQDVTEWRGVAQSTYQKEFWAIFDICLNKLPAQQARVFMMREHLEMSSAEICQECEISLSNLNVLLHRARLRLQECLSRNWFREESK	No		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_000963675.1	NZ_CP011099	NZ_CP011099_1[1041692;1042861] (evidence-level=4), NZ_CP011099_2[1217037;1217151] (evidence-level=1), NZ_CP011099_3[1566615;1566689] (evidence-level=1), NZ_CP011099_4[1803545;1803623] (evidence-level=1), NZ_CP011099_5[1815731;1815805] (evidence-level=1),	5	Nb_arrays_evidence-level_1=4,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=1	CAS-TypeIC[1034769;1041501],	1	CAS-TypeIC (n=1),