Results - Acr-Aca DB

Anti-CRISPR Results - GCF_000993765.1 (Total 5 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	Self Target Outside 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_023605207.1	517035	517421	-	129	2	7.393	Acr	0.40405831	195	-2.9251795	82	-2.9251795	PHAGE_Strept_315.5_NC_004588-gi\|28876433\|ref\|NP_795608.1\|\|5.91e-72	-	MVKINEMLSKYNIKLFEFPDTMWKRSGFYYPDLRIIYVNQNLSQIEKEKVILHELGHIEHDPKQYQRLLLKYENQADRFMIRELIKNYLSSHDVVDFNWLQFATTYQISTTWGQKMIQDEFYKIVSGS	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_011888679.1	517405	517746	-	114	-5	4.558	WP_070677359.1\|HTH_XRE-0-AcrIIA15\|39.1\|2.4e-06	0.312698541	45	-1.479943	23	-1.479943	PHAGE_Strept_YMC_2011_NC_018285-gi\|399498689\|ref\|YP_006561232.1\|\|2.72e-29	-	MDEKDLKRIIESRYNSVRAFAIENDIPYTTMRSILERGVMNAKAETIFKICDILGINPESFAEEKTDWQATIDLSNLREKVVMFDGKPLSDKDVEKIEAIIKISLGVGNGEDK	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_011054585.1	519407	519592	+	62	4	10.0215	WP_044774185.1\|HTH_3\|AcrIIA14\|70.5\|2.3e-19	0.165635428	599	-4.274774	201	-4.274774	PHAGE_Strept_315.2_NC_004585-gi\|28876251\|ref\|NP_795440.1\|\|7.84e-38	-	MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFDDVVKIADVLGVSLDEFR	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_011888682.1	519663	519914	+	84	3	9.8965	Acr	0.580951121	72	-1.8467827	34	-1.8467827	PHAGE_Strept_A25_NC_028697-gi\|966201372\|ref\|YP_009191509.1\|\|3.76e-54	-	MDNILMSLSDWIKEFIEKTVNKLVQMKLDELNAELWTREKVAERLNMSPSTFDKYYRRDKNFPKELPAVRWKKAEIIAWLNNK	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_011017881.1	519945	520082	+	46	4.5	10.3182	Acr	0.36143333	253	-3.274272	101	-3.274272	PHAGE_Strept_T12_NC_028700-gi\|966201493\|ref\|YP_009191681.1\|\|9.11e-28	-	MKLLDFIFAKPKKQEPIKHDTLRASSEKQWAEFDAYMRKQYGRQA	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_029714276.1	822786	823049	+	88	0.5	7.0169	Acr	0.722515951	50	-1.5910153	25	-1.5910153	PHAGE_Strept_T12_NC_028700-gi\|966201491\|ref\|YP_009191679.1\|\|1.73e-57	-	MNEIENKLEELEEMVINMDEVDVVIPWKIAKNLLQRAGYLSEEEHRLLSWRLGKSKYAGKRSEKVRNLLEGLRNSGSSDGNRTQNKF	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_011054584.1	823086	823382	+	99	4	10.1301	Acr	0.738416785	209	-3.0048175	88	-3.0048175	PHAGE_Strept_315.2_NC_004585-gi\|28876250\|ref\|NP_795441.1\|\|9.21e-68	-	MAIEIFGPEFRKNLLEDLIALNMEAMKIAQTKNAKSIEWITMKRLEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_023610888.1	823529	823843	+	105	-2.5	5.2303	AcrIIA1-1-WP_002828465.1\|HTH_3\|45.2\|1e-09	0.14108494	46	-1.5097435	24	-1.5097435	PHAGE_Strept_315.2_NC_004585-gi\|28876248\|ref\|NP_795443.1\|\|7.89e-72	-	MNRIKELRKEKGLTQQDLAEEIYVHYRTIQRWENEHKIALDQAQLLADHFDVSVAYLLGYSDTTKDNKDFITISVKEYNELKNRSDVLDGIIETLKDKKCESYF	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_002982695.1	1678223	1678429	-	69	0	6.2006	WP_060665735.1\|HTH_3\|AcrIIA1\|65.1\|5.6e-21	0.149128906	245	-3.227825	97	-3.227825	PHAGE_Brevib_Abouo_NC_029029-gi\|971767218\|ref\|YP_009220108.1\|\|1.02e-10	-	MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTINLCIAICRVLDKTLDDLFWEADDSR	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_002982690.1	1678426	1678965	-	180	7.5	9.9668	Acr	0.359153448	1839	-5.960142	348	-5.960142	-	-	MSYKDLKEKRIMFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGGVAFVLTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYTIGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLSMGASIFYRHYLDAKEADE	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 5	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_015056011.1	1824790	1824918	-	43	0	6.4489	Acr	0.566027781	382	-3.778985	Not found in Prophage	Not found in Prophage	-	-	MILSHSLQFDKITFFLQKDLRSSHEYDNIISSLFEKTEAQVK	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 5	Medium Confidence	Streptococcus pyogenes	NZ_CP007537.1	WP_076640006.1	1824974	1825240	-	89	-3	4.7906	AcrIIA15-1-WP_058013669.1\|HTH_24\|49.3\|2.4e-16	0.145085141	886	-4.7482767	Not found in Prophage	Not found in Prophage	-	-	MLRDLLKGTLRFGQLKSSIGSVSQKVLTAQLRAMEADGLVHREVYAEVPPRVEYSLTETGLSLAPVIEAMSDWGQTYQEKHADLFEEG	No		Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_000993765.1	NZ_CP007537	NZ_CP007537_1[598462;598756] (evidence-level=4), NZ_CP007537_2[758811;758946] (evidence-level=1), NZ_CP007537_3[864821;864921] (evidence-level=1), NZ_CP007537_4[1055712;1055827] (evidence-level=1), NZ_CP007537_5[1751135;1751252] (evidence-level=1), NZ_CP007537_6[1754092;1754225] (evidence-level=1),	6	Nb_arrays_evidence-level_1=5,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=1	CAS-TypeIC[590301;598313], CAS-TypeIIA[1097471;1103436],	2	CAS-TypeIC (n=1), CAS-TypeIIA (n=1),