Results - Acr-Aca DB

Anti-CRISPR Results - GCF_002285595.1 (Total 9 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006250233.1	1093094	1093474	-	127	6.5	9.3767	Acr	0.267640322	583	-4.04282	Not found in Prophage	Not found in Prophage	-	-	MAGLSIICPFCGNTARIRGSSRPSLLSYQAQLTCSNCGQLKADFVGQLINIKRAVFIECDEANQWDKPENELIKEGKIQGKDNAQRLKELRGSQQDLFAKVPGQLPPEKITPAEKIAKRANLSKTH	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 1	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006253560.1	1093474	1093665	-	64	5	10.1414	AcrIIA13-0-WP_006662529.1\|HTH_17\|33.3\|2.8e-07	0.153687408	169	-2.7635581	Not found in Prophage	Not found in Prophage	PHAGE_Ralsto_RSY1_NC_025115-gi\|691326898\|ref\|YP_009067125.1\|\|2.66e-07	-	MTYSEQSYLNVKDVCEMLQLNRSTIYRQIKQGIFPKPTKIGKSSRWKFADIKAFLEPKPQEAN	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 1	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006250234.1	1092844	1093026	-	61	7	10.5311	Acr	0.26581145	2023	-5.5118656	Not found in Prophage	Not found in Prophage	-	-	MRKICKEIKAGLTISEGVRFFLKSLGIGLFLALFFYFLPYLAEFIIAVKKQLAKKSAYFQ	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 2	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006250080.1	1126304	1126510	+	69	0	6.1804	WP_055150624.1\|HTH_XRE\|AcrIIA1\|48.7\|3.6e-06	0.145068298	983	-4.6471167	232	-4.6471167	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749643\|ref\|YP_009203423.1\|\|1.85e-44	-	MNKIAEIRNQIGISQAQLAVQIGWGQPRIANYETGNRTPSIYVAQKIVEGLNELGANVRIDDVFPVGN	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 2	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006253537.1	1126531	1126791	+	87	2	8.549	WP_142130479.1\|HTH_Tnp_ISL3\|AcrIIA1\|36.7\|0.0091	0.553262354	180	-2.8368797	53	-2.8368797	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749644\|ref\|YP_009203424.1\|\|1.86e-57	-	MPRNELTKNARAIADLIHRKSATVTHKKLARAIGLSESQFSRTFADNVEMVAVIIDYLSIELADKDELLELKEKRYKRINLEEATT	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 3	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249172.1	1163550	1164068	-	173	3	8.9234	AcrVA3-0-WP_077553360.1\|DUF1870\|68.4\|1.8e-39	0.225303573	736	-4.3002214	178	-4.3002214	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749619\|ref\|YP_009203399.1\|\|1.39e-126	-	MTTQVTPQIMRIIGQIVAATYGDDVPTNVQTIILRYPIRGIGFISSRRELSINNGEIARLMDKIPGDLEDPKDGMPFDCQGAFWLGYYQYCKLSNDVKNYTSKELSIIGESLYGTQWQSNLARDLRLSDARRVREWVAGERKIPFGVWADLTELVKAKKANLSSILKKLTID	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 3	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_015484183.1	1164138	1164728	-	197	-2.5	5.1081	Acr	0.55296539	194	-2.901127	58	-2.901127	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749620\|ref\|YP_009203400.1\|\|2.90e-144	-	MTTQITTAQINDLLKSHDIQGYANEWQGRRIYINLSAKNNESRGDRNYQLYIDLATGELVSKLGKGLTTREFDAAVKAFENAFNAKDTAENTSPAESKETEQENKQETTKLVITKPTLKGSEKQIAWADEIINLFIAKIGDTSIPVTATQEQITQAQAMVDNFFAMTNAGKWIEKFKGLNDSSEPKQFWLSVKYGW	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 4	High Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249171.1	1415071	1415661	+	197	-1.5	5.3826	Acr	0.514313197	386	-3.6100926	Not found in Prophage	Not found in Prophage	PHAGE_Mannhe_vB_MhS_1152AP2_NC_028956-gi\|971760512\|ref\|YP_009213787.1\|\|5.86e-144	-	MTTQITTAQINDLLKSHDIQGYANEWQGRRIYINLSAKNNESKGDRNYQLYIDLATGELVSKLGKGLTTRAFDAAVKAFENAFNAKDTAENTAPVESKETEQENKQETTKLVITKPTLKGSEKQIDSANEIINLFIAKIGDTSIPVTATQEQITQAQAMVDNFFAMTNAGKWIEKFKGLNDNSEPKQFWLSVKYGW		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 4	High Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249172.1	1415731	1416249	+	173	3	8.9234	AcrVA3-0-WP_077553360.1\|DUF1870\|68.4\|1.8e-39	0.225303573	736	-4.3002214	178	-4.3002214	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749619\|ref\|YP_009203399.1\|\|1.39e-126	-	MTTQVTPQIMRIIGQIVAATYGDDVPTNVQTIILRYPIRGIGFISSRRELSINNGEIARLMDKIPGDLEDPKDGMPFDCQGAFWLGYYQYCKLSNDVKNYTSKELSIIGESLYGTQWQSNLARDLRLSDARRVREWVAGERKIPFGVWADLTELVKAKKANLSSILKKLTID		Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 5	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006250080.1	1450545	1450751	-	69	0	6.1804	WP_055150624.1\|HTH_XRE\|AcrIIA1\|48.7\|3.6e-06	0.145068298	983	-4.6471167	232	-4.6471167	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749643\|ref\|YP_009203423.1\|\|1.85e-44	-	MNKIAEIRNQIGISQAQLAVQIGWGQPRIANYETGNRTPSIYVAQKIVEGLNELGANVRIDDVFPVGN	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 5	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006253537.1	1450264	1450524	-	87	2	8.549	WP_142130479.1\|HTH_Tnp_ISL3\|AcrIIA1\|36.7\|0.0091	0.553262354	180	-2.8368797	53	-2.8368797	PHAGE_Mannhe_vB_MhS_535AP2_NC_028853-gi\|971749644\|ref\|YP_009203424.1\|\|1.86e-57	-	MPRNELTKNARAIADLIHRKSATVTHKKLARAIGLSESQFSRTFADNVEMVAVIIDYLSIELADKDELLELKEKRYKRINLEEATT	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 6	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249194.1	1588996	1589472	-	159	-9	4.3936	AcrIIA7-2-WP_000349509.1\|HTH_30\|53.5\|2e-40	0.187968602	759	-4.3396654	184	-4.3396654	PHAGE_Entero_c_1_NC_019706-gi\|428781736\|ref\|YP_007111504.1\|\|8.17e-55	-	MDNLFDLKLNINQIAELTGLHRQTVSQRVAGLNPALGSNSKLKLYALRDLILTGLAEKMSADVDSLSPADRRAWFQSENERLKFEKEIGELIPASEVALEMSALAKTVVQALETLPDILERDCGLQPKDLIRVQQVTDDVRDQMALHIQEVTTDTENE	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 6	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249195.1	1589620	1590018	-	133	-7.5	4.2978	Acr	0.544831345	490	-3.8606262	123	-3.8606262	-	-	MIVKLKLGAVVVLSQVKQATIAYAGSEAYQTAIEQAKKGLLDEDKGKPFETVLHFPAVYADEDGQEEICPEQIATTVRSDNVSGEPVAVVLIPDDNVVGELQSIFIYKTDYAEIFTDNGVKLSAVRTSPAPR	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 7	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249610.1	2622957	2623487	-	177	7.5	9.8361	Acr	0.101998711	2157	-5.6222377	380	-5.6222377	PHAGE_Mannhe_vB_MhM_3927AP2_NC_028766-gi\|971741504\|ref\|YP_009196052.1\|\|2.60e-69	-	MSENSLKTHYSAKELAELSLACLPKTKQGVLYQAKKQGWTTHKKVGVGGEILEFALSNLPQEIQTEIRSRFMSAVVEAKPKKLPAVRAEVDVGNLTTKQREIADARMALVAYVLELEGSMSRIKAITYLCNLAKQGEMPPHLVELVAVANAKKTAKRTIVPIFSPIMPDFPLDSRD	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 7	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249609.1	2623503	2623766	-	88	7	10.4095	WP_005567622.1\|HTH_35-3-AcrIF9\|62.3\|1.2e-19	0.146408531	270	-3.2246957	76	-3.2246957	PHAGE_Haemop_SuMu_NC_019455-gi\|418489037\|ref\|YP_007002910.1\|\|1.25e-46	-	MSTLEDIKKTAKDWHRADIIAALHKAGWSLRQLSLKHGYSQSSTLKNAVDRPWLKGERIIAEAIGISPEEIWPERYAQRNHKKFADR	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 8	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249608.1	2623950	2624432	+	161	-0.5	6	AcrIIA7-3-WP_057903263.1\|HTH_3\|35.1\|0.0046	0.04722432	1286	-4.9468126	276	-4.9468126	PHAGE_Haemop_SuMu_NC_019455-gi\|418489036\|ref\|YP_007002909.1\|\|3.43e-11	-	MKIECKKVIGFGNRIEQSRKNAKLSRSEVCDALGGIAISTLQAWEADTREPPISKLMALSQILNVEPCYLLTGERHSQSLNVTREPQPVYATKPQTEEGEVVVIKAKLQEAIETLEEVLEITQREMKPAGKAQMVWAFYELLTQEKSEKEKMVGLLKLVA	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 8	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249607.1	2624444	2624695	+	84	-1	5.6002	Acr	0.373114555	97	-2.2405803	Not found in Prophage	Not found in Prophage	-	-	MDKQAILKLFRDNSTAGNSQPSQEPIQVFNNSNVIIQNGDNATVIAGCTVDNNTNLTCADKQRVHDLIHSLEQRNRASRDEGA	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 9	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249755.1	2640809	2641093	-	95	2.5	7.6418	Acr	0.128970463	342	-3.4659867	Not found in Prophage	Not found in Prophage	-	-	MRYWLISLSILLSGCVVPVTPTGQAGIPMPIIIGVSDPLDSKEVHICTLKPFTQEYRSEHSSRGRAKLNVQKQCRANHSEMFCEEKDIVCKTYD	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 9	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249756.1	2641123	2641308	-	62	9	10.1765	Acr	0.149426432	473	-3.8250227	Not found in Prophage	Not found in Prophage	-	-	MKCRQATELISQSCDEKLRLQQHMRLQLHLLVCPKCRNFNKNTKKLGKILRAYCNDKDAPF	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica
Acr-Aca 9	Medium Confidence	Mannheimia haemolytica	NZ_CP023046.1	WP_006249757.1	2641305	2641871	-	189	2.5	7.0858	WP_095590313.1\|HTH_23-0-AcrIF6\|37.5\|1.3e-06	0.135199451	111	-2.3267798	Not found in Prophage	Not found in Prophage	PHAGE_Pseudo_PA11_NC_007808-gi\|149408171\|ref\|YP_001294605.1\|\|0.005	-	MKSLSSTQIEEIRKQMVKFATLQLADKDLAEDVVQDALTNAYKHSASFRREAALKTWIFAILKNKILDLLRTRKRHIPVSSLCEEEESPSAFFDRHDHWLEHQDVTEWRGVAQSTYQKEFWAIFDICLNKLPAQQARVFMMREHLEMSSAEICQECEISLSNLNVLLHRARLRLQECLSRNWFREESK	No	Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Mannheimia; Mannheimia haemolytica

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_002285595.1	NZ_CP023046	NZ_CP023046_1[998942;999016] (evidence-level=1), NZ_CP023046_2[1545624;1546726] (evidence-level=4), NZ_CP023046_3[1811069;1811147] (evidence-level=1), NZ_CP023046_4[1823256;1823330] (evidence-level=1),	4	Nb_arrays_evidence-level_1=3,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=1	CAS-TypeIC[1538689;1545433],	1	CAS-TypeIC (n=1),