Results - Acr-Aca DB

Anti-CRISPR Results - GCF_900475335.1 (Total 8 loci with Aca homologs)

1. Guilt-by-Association

1.1 Guilt-by-Association (Tabular View)

Loci ID	Classification	Organism	Refseq ID	Protein ID	Start	End	Strand	aa Length	Charge	Isoelectric Point	Acr/Aca	PaCRISPR_score	AcRanker Rank	AcRanker Score	AcRanker Rank Prophage	AcRanker Score Prophage	MGE/Propahge Metadata	Acr_Hit	sequence	Self Target w/in 5000 BP	lineage(Kingdom;Phylum;Class;Order;Family;Genus;Species;SubSpecies)
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_111676601.1	486912	487166	+	85	1	7.7768	WP_150558887.1\|HTH_AsnC-type-0-AcrIIA15\|43.2\|0.0022	0.43498253	10	-0.17715615	8	-0.17715615	PHAGE_Strept_315.4_NC_004587-gi\|28876369\|ref\|NP_795552.1\|\|1.14e-21	-	MSNADEWRVYPEELARRCKDSESAIRSQLKALENAKYIRTYRKSFGGRYGTETYRFCSDRKISDEAFNTLKAEQDLELEKFANT	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 1	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_111690648.1	486618	486803	+	62	6	11.0374	Acr	0.337228033	145	-2.691203	55	-2.691203	PHAGE_Strept_315.4_NC_004587-gi\|28876370\|ref\|NP_795551.1\|\|1.20e-35	-	MNKLELFLLATTVILAIITRLQHEVIKKHNSPENKRRIFREVALENSKGWSEKRSRGEVVS	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_023611751.1	1209167	1209382	+	72	4.5	10.1012	WP_046390348.1\|HTH_3\|AcrIIA15\|67.1\|4.7e-19	0.495652305	89	-2.108224	40	-2.108224	PHAGE_Strept_PH15_NC_010945-gi\|190151474\|ref\|YP_001974385.1\|\|3.25e-16	-	MKADSKKIEWLLENASQYSIAKGTGITQSKLSYLLKGIKEPSHPKAIKIENLSLEIASKLTNFSEEIQKNK	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 2	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_003055855.1	1209451	1209690	+	80	6	10.3354	Acr	0.64763483	3	0.1108543	2	0.1108543	-	-	MKTFNIIVSESANLKEHSSELVDNIIYKVEAKNRREAFKKAREEYSFSSKWKFNMRDLTAIDNTHRRAWGRRYLRVEEA	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_019418742.1	1242057	1242314	-	86	2	7.8464	Acr	0.250561726	46	-1.4793746	21	-1.4793746	PHAGE_Strept_315.4_NC_004587-gi\|28876369\|ref\|NP_795552.1\|\|2.51e-49	-	MLLTILRNKEEWRVYPEELAKRHSDGLASVRAGLKELEQAGYVRTYKKIIRRSDGLQHYRFCSDCKISDETYKQLVEQIERELSD	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_002986881.1	1242408	1242593	-	62	6.5	11.0643	Acr	0.397676492	361	-3.7733803	109	-3.7733803	PHAGE_Strept_315.4_NC_004587-gi\|28876370\|ref\|NP_795551.1\|\|1.90e-36	-	MNKLELFLLTTTIILAIIARIQYEVIKKHNSPENKRRIFREVALENSKGWNEKRSRGGVIS	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 3	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_032463372.1	1242622	1242879	-	86	0.5	6.9468	WP_103143842.1\|HTH_26\|AcrIIA15\|36.4\|0.0086	0.753866099	83	-2.0270007	37	-2.0270007	PHAGE_Strept_315.4_NC_004587-gi\|28876371\|ref\|NP_795550.1\|\|6.51e-57	-	MQSQLTYDLLKKQIAEELFDEFKKLIQEKDLANQWVNQTTLVNEYGYSWQTIKCMESYGLKSFKNGKDKMYCLADVNEIKHLMKQ	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011054768.1	1245959	1246318	+	120	-2	5.2405	WP_065549612.1\|HTH_3\|AcrIIA1\|32.5\|9.8e-12	0.090100337	53	-1.6907718	24	-1.6907718	PHAGE_Strept_315.4_NC_004587-gi\|28876377\|ref\|NP_795544.1\|\|1.41e-84	-	MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTANTDPIEKIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELNDEDIDLITSILETRIKNRK	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_076634137.1	1246332	1246712	+	127	-3.5	5.5319	Acr	0.409840823	5	0.025740325	3	0.025740325	PHAGE_Strept_315.4_NC_004587-gi\|28876378\|ref\|NP_795543.1\|\|9.04e-92	-	MMTPETVCQEKGIDLIYFDGRGTNIPGMFNKKHNVIAIDTYLDGIYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQFMEKYELTSIADEVMVKEEFKNLI	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 4	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_002986895.1	1246723	1247244	+	174	2	8.3388	Acr	0.51164979	251	-3.3098311	88	-3.3098311	PHAGE_Strept_315.4_NC_004587-gi\|28876379\|ref\|NP_795542.1\|\|1.44e-120	-	MKKIVYLFTLSVLIVCLGACTGGSKKDTTSKTPSSDTSKVSGDMSEKEYFDTLISKIDKVTTDNYKSDEYLFYDYKTILRDPKKYFSLKVRINNLKIIQISDKDKYTKMLANTPNGDLYMLFIETKRLETKLLETDNITINGRYLLSYEYTTTSGSENSVPLIYIDGYLLLDK	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 5	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011054822.1	1439255	1439506	-	84	1.5	8.4933	Acr	0.610054477	79	-1.9607337	35	-1.9607337	PHAGE_Strept_315.5_NC_004588-gi\|28876430\|ref\|NP_795611.1\|\|3.13e-56	-	MDNILMSLSDWIKEFIEKTVNKLVQMKLDELNAELWTREKVAERLNMSPGTFDKYYRHDKNFPKELPAVRWKKAEIIDWLNNK	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 5	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_111711017.1	1439601	1439819	-	73	0	6.2786	WP_000272856.1\|HTH_XRE-3-AcrIIA15\|52.3\|7.8e-14	0.15822778	831	-4.774135	199	-4.774135	PHAGE_Strept_315.5_NC_004588-gi\|28876431\|ref\|NP_795610.1\|\|9.27e-47	-	MAVDYLRVKAERIARGYTQDYMAKQLGWSDRARYAKRENGFVSFDADELAKVAEVLGISKDDIGIFFTYNVP	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 6	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011528540.1	1440008	1440367	+	120	2.5	9.6528	WP_070677359.1\|HTH_XRE-0-AcrIIA15\|33.3\|2.8e-09	0.076178692	243	-3.2765336	85	-3.2765336	PHAGE_Strept_315.5_NC_004588-gi\|28876432\|ref\|NP_795609.1\|\|4.15e-82	-	MRTNDEIIDLMDNIRKEKRISISELSRKVGMSKSGVSLYFNKARKFPLDRANLFAKALGTTPEHIIGVTPKNSPTQTIDLSNLRERVVMFDGKPLSDDDVEKIEAIIKLSLGVGNGEDR	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 6	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011054824.1	1440351	1440728	+	126	1	6.7615	Acr	0.459643786	77	-1.9583762	33	-1.9583762	PHAGE_Strept_315.5_NC_004588-gi\|28876433\|ref\|NP_795608.1\|\|1.24e-89	-	MVKIDEILNQYNIKLFEFPDTMWDRSGFYYPDHRIIYVNKNLSEKDRKKVILHELGHIEHDPKQYQRLLLKYENQADRFMVRELIKDYLSDHDIYSFDWLKFANHYKISTSWGQEMIQDEFRKLI	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 7	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011285304.1	1779355	1779600	-	82	-5.5	4.4292	Acr	0.718779749	42	-1.4003041	Not found in Prophage	Not found in Prophage	-	-	MLKKINTYRRLEIIKNKLDEASKDSIEDIMLDWFRALHYALKVDDTIDLPTFLEFKDNKALRDKIMADLGDFDPFEDLNIE	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 7	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_014407964.1	1779575	1779850	-	92	-0.5	6.2333	Acr	0.67500836	234	-3.2469954	Not found in Prophage	Not found in Prophage	PHAGE_Acidia_3_NC_010155-gi\|162329293\|ref\|YP_001604347.1\|\|0.002	-	MNSNLKKRVDKLRRLHSLDNASGIVFVEYADGKYQIKKQDHVPKFIETRLIAEFESEEEAENFLSTIPSGYIIFWDIFPEEVEHVKKNKYL	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 7	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011285306.1	1779840	1780223	-	128	-2.5	5.2629	AcrIIA10-0-Minot_Diet_SRR5088933_NODE_85_length_14576_cov_106.044900_21\|HTH_Tnp_1_2\|31.9\|2.2e-10	0.146171528	64	-1.8383281	Not found in Prophage	Not found in Prophage	PHAGE_Staphy_phiJB_NC_028669-gi\|966198884\|ref\|YP_009188714.1\|\|6.60e-04	-	MIFIEHGLTPKQEKFMVAMVTSKTITEAAERAGITRGTAHRYLKDITFKKACRRYRSELMQQTTSLLQSASIEAVEVLRNIMLDDSISPYARQQSAQTILSTAYKAHELDDIVEMVEELEARFEDEQ	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 7	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011285307.1	1780220	1780486	-	89	-3	4.8667	Acr	0.646810322	87	-2.0512228	Not found in Prophage	Not found in Prophage	-	-	MMSLECLRIYLKKSQFTELEHLLFRIIVLGGYPDDMYFPSRVRTIITSLVNNIRKNLDSEGYRSVEELEEAIEKAISEHDEITQKGGG	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 8	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_076638096.1	1786091	1786360	-	90	-5	4.4356	Acr	0.763029688	138	-2.6478932	Not found in Prophage	Not found in Prophage	-	-	MRTDKGEMIMKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQGIFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 8	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011285320.1	1786390	1786956	-	189	-1	6.1237	Acr	0.094615278	103	-2.270956	43	-2.270956	PHAGE_Clostr_phiCT9441A_NC_029022-gi\|971821649\|ref\|YP_009219374.1\|\|2.38e-29	-	MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRARDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGLYEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLTDLQDVDSLQDLRWKMAKLYHVIETLDEY	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes
Acr-Aca 8	Medium Confidence	Streptococcus pyogenes	NZ_LS483520.1	WP_011285321.1	1786972	1787160	-	63	7	10.5728	WP_045175812.1\|HTH_3\|AcrIIA15\|42.9\|7.6e-05	0.296708486	1177	-5.245202	239	-5.245202	PHAGE_Lactoc_lato_NC_004746-gi\|30089888\|ref\|NP_839918.1\|\|1.47e-04	-	MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRIYASVMEWLAEDY	No	Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus pyogenes

1.2 Guilt-by-Association (Graphic View)

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1.3 Guilt-by-Association (Jbrowse View)

2. Homology Based

No result on Homology Based method

3. CRISPRCasFinder Summary

GCF	NC_ID	CRISPR arrays	Nb CRISPRs	Evidence levels	Cas clusters	Nb Cas	Cas Types/ Subtyes
GCF_900475335.1	NZ_LS483520	NZ_LS483520_1[365518;365636] (evidence-level=1), NZ_LS483520_2[801662;802489] (evidence-level=4), NZ_LS483520_3[1000664;1000765] (evidence-level=1), NZ_LS483520_4[1251283;1251645] (evidence-level=4), NZ_LS483520_5[1787176;1787272] (evidence-level=1),	5	Nb_arrays_evidence-level_1=3,Nb_arrays_evidence-level_2=0,Nb_arrays_evidence-level_3=0,Nb_arrays_evidence-level_4=2	CAS-TypeIIA[795594;801559], CAS-TypeIC[1251794;1259813],	2	CAS-TypeIC (n=1), CAS-TypeIIA (n=1),