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Annotate proteins using DIAMOND, HMMER via CAZy, dbCAN, dbCAN-sub respectively

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Note: We encourage users to leave your email address if submitting an entire genome or proteome; the result page will be emailed to you when the job is done.
2/19/2024: dbCAN website was down for two days; see Twitter announcement. Please use mirror site in the future when this happens again.

8/2/2023: dbCAN HMMdb v12.0 is released; see readme.txt for details. The DIAMOND db is also updated (7/26/2023).
2/11/2023: You can now predict substrates for CAZymes and CGCs! Please do not use ":" in your FASTA sequence names. This will cause problem in substrate prediciton.
5/25/2022: If your gff file is from NCBI, please check the last column, replace 'Name' tag with 'ID', and 'ID' with 'Name' (only affects CGC predictions).

For future announcement, please follow us on Twitter.

Choose Sequence Type:

Protein sequence (example) ? Nucleotide sequence (example) ?

Select Tools To Run:

HMMER: dbCAN (E-Value < 1e-15, coverage > 0.35)  DIAMOND: CAZy (E-Value < 1e-102)  HMMER: dbCAN-sub (E-Value < 1e-15, coverage > 0.35)  CGCFinder (Distance <= 2, signature genes = CAZyme+TC)?