CAZyme Information
You are here: Home >
Sequence: WP_015718475.1
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
Signalp annotations |
TMHMM annotations |
PSSpred annotations |
LipoP annotations
Basic Information help
| Species | Geobacter sp. M18 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAZyme ID | WP_015718475.1 | |||||||||||||
| CAZy Family | GH13; | |||||||||||||
| CAZyme Description | maltooligosyl trehalose synthase | |||||||||||||
| CAZyme Property |
|
|||||||||||||
| Genome Property |
|
|||||||||||||
| Gene Location | Start: 137256; End: 140216 Strand: + | |||||||||||||
| View CDS | CDS sequence | |||||||||||||
| UniProt ID | E8WL25; | |||||||||||||
| InterPro Annotation | E8WL25; | |||||||||||||
Genomic Context If it does not show, please wait or refresh. help
Enzyme Prediction help
| metacyc | EC |
|---|---|
| 5.4.99.15-RXN; | 5.4.99.15; |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | Start | End | Domain Description |
|---|---|---|---|---|---|
| PRK14511 | PRK14511 | 0.0 | 9 | 985 |
maltooligosyl trehalose synthase; Provisional
|
| PRK14507 | PRK14507 | 0.0 | 8 | 985 |
putative bifunctional 4-alpha-glucanotransferase/malto-oligosyltrehalose synthase; Provisional
|
| cd11336 | AmyAc_MTSase | 0.0 | 14 | 875 |
Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase). Maltooligosyl trehalose synthase (MTSase) domain. MTSase and maltooligosyl trehalose trehalohydrolase (MTHase) work together to produce trehalose. MTSase is responsible for converting the alpha-1,4-glucosidic linkage to an alpha,alpha-1,1-glucosidic linkage at the reducing end of the maltooligosaccharide through an intramolecular transglucosylation reaction, while MTHase hydrolyzes the penultimate alpha-1,4 linkage of the reducing end, resulting in the release of trehalose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.
|
| COG3280 | TreY | 0.0 | 10 | 983 |
Maltooligosyltrehalose synthase [Carbohydrate transport and metabolism].
|
| TIGR02401 | trehalose_TreY | 0.0 | 12 | 985 |
malto-oligosyltrehalose synthase. This enzyme, formally named (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase, is the TreY enzyme of the TreYZ pathway of trehalose biosynthesis, an alternative to the OtsAB pathway. Trehalose may be incorporated into more complex compounds but is best known as compatible solute. It is one of the most effective osmoprotectants, and unlike the various betaines does not require nitrogen for its synthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
|
CAZyme Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADW11605.1| GH13 | 0.0e+00 | 1 | 986 | 1 | 986 |
| ACH37165.1| GH13 | 0.0e+00 | 1 | 984 | 1 | 990 |
| ACT16201.1| GH13 | 0.0e+00 | 1 | 986 | 1 | 992 |
| ACM19577.1| GH13 | 0.0e+00 | 1 | 984 | 1 | 993 |
| ANA39916.1| GH13 | 0.0e+00 | 1 | 986 | 1 | 985 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3HJE_A | 4.8e-49 | 455 | 911 | 297 | 665 |
Chain A, Crystal Structure Of Sulfolobus Tokodaii Hypothetical Maltooligosyl Trehalose Synthase
|
| 1IV8_A | 1.4e-24 | 13 | 180 | 3 | 163 |
Chain A, Crystal Structure Of Maltooligosyl Trehalose Synthase
|
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| sp|Q44315|TREY_ARTSQ | 5.2e-83 | 286 | 985 | 179 | 769 |
Maltooligosyl trehalose synthase OS=Arthrobacter sp. (strain Q36) GN=treY PE=1 SV=1
|
| sp|P9WQ20|TREY_MYCTO | 3.6e-76 | 286 | 945 | 183 | 732 |
Putative maltooligosyl trehalose synthase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=treY PE=3 SV=1
|
| sp|P9WQ21|TREY_MYCTU | 3.6e-76 | 286 | 945 | 183 | 732 |
Putative maltooligosyl trehalose synthase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=treY PE=1 SV=1
|