| Basic Information | |
|---|---|
| Species | Volvox carteri |
| Cazyme ID | Vocar20003404m |
| Family | GH99 |
| Protein Properties | Length: 409 Molecular Weight: 45485.8 Isoelectric Point: 4.8767 |
| Chromosome | Chromosome/Scaffold: 35 Start: 318790 End: 323812 |
| Description | |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH99 | 33 | 365 | 0 |
| VHAFYYLWYTEPSAGGWTHWDHEVLPHWDAAVAAKHTHGVRFEPPDCLHSPYYPLRGPYSSTSRELIRQHLVEMEQYGIGVLVASWWGPPWRQGSHDTQM VNTDSRLEMVIRELEESGSKVRIAFHLEPYEGRTKETVHEDLVYLSKKYRDSPAVLQINGLPVYYVYDSYRLPASDWAQLLRRNDGPLNVRGTPADGFFL GLWLDRDDGDEDILPAGFDGFYTYFSRWAVSKDLLFVPSIGPGYHGGCPGNKKQSERPSRRETLDHDTTMLLYRALWSAALSAGVQMVSITSYNEWGEGT QIEPAVPRETRLGCQYLSYEPASPYLYLEITSE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 409 Download |
| MMILSAGFWL VVTALAALAL QAQGGNFPPM YRVHAFYYLW YTEPSAGGWT HWDHEVLPHW 60 DAAVAAKHTH GVRFEPPDCL HSPYYPLRGP YSSTSRELIR QHLVEMEQYG IGVLVASWWG 120 PPWRQGSHDT QMVNTDSRLE MVIRELEESG SKVRIAFHLE PYEGRTKETV HEDLVYLSKK 180 YRDSPAVLQI NGLPVYYVYD SYRLPASDWA QLLRRNDGPL NVRGTPADGF FLGLWLDRDD 240 GDEDILPAGF DGFYTYFSRW AVSKDLLFVP SIGPGYHGGC PGNKKQSERP SRRETLDHDT 300 TMLLYRALWS AALSAGVQMV SITSYNEWGE GTQIEPAVPR ETRLGCQYLS YEPASPYLYL 360 EITSEGSKRL GQLTAGGEGE TCQATSAGGN GDDGGGVGDG GSDDIAEQ* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11576 | GH99_GH71_like_2 | 3.0e-6 | 33 | 370 | 395 | + Uncharacterized glycoside hydrolase family 99-like domain. This family of putative glycoside hydrolases resembles glycosyl hydrolase families 71 and 99 (following the CAZY nomenclature) and may share a similar catalytic site and mechanism. The domain may co-occur with other domains involved in the binding/processing of glycans. | ||
| cd11578 | GH99_GH71_like_1 | 4.0e-14 | 79 | 339 | 294 | + Uncharacterized glycoside hydrolase family 99-like domain. This family of putative glycoside hydrolases resembles glycosyl hydrolase families 71 and 99 (following the CAZY nomenclature) and may share a similar catalytic site and mechanism. | ||
| cd11575 | GH99_GH71_like_3 | 3.0e-16 | 33 | 363 | 370 | + Uncharacterized glycoside hydrolase family 99-like domain. This family of putative glycoside hydrolases resembles glycosyl hydrolase families 71 and 99 (following the CAZY nomenclature) and may share a similar catalytic site and mechanism. | ||
| cd11573 | GH99_GH71_like | 1.0e-30 | 97 | 363 | 292 | + Glycoside hydrolase families 71, 99, and related domains. This superfamily of glycoside hydrolases contains families GH71 and GH99 (following the CAZY nomenclature), as well as other members with undefined function and specificity. | ||
| cd11574 | GH99 | 1.0e-112 | 33 | 365 | 356 | + Glycoside hydrolase family 99, an endo-alpha-1,2-mannosidase. This family of glycoside hydrolases 99 (following the CAZY nomenclature) includes endo-alpha-1,2-mannosidase (EC 3.2.1.130), which is an important membrane-associated eukaryotic enzyme involved in the maturation of N-linked glycans. Specifically, it cleaves mannoside linkages internal to N-linked glycan chains by hydrolyzing an alpha-1,2-mannosidic bond between a glucose-substituted mannose and the remainder of the chain. The biological function and significance of the soluble bacterial orthologs, which may have obtained the genes via horizontal transfer, is not clear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001056614.1 | 0 | 33 | 363 | 100 | 436 | PREDICTED: similar to mannosidase, endo-alpha [Rattus norvegicus] |
| RefSeq | XP_001170001.1 | 0 | 33 | 363 | 105 | 441 | PREDICTED: similar to mannosidase, endo-alpha-like isoform 3 [Pan troglodytes] |
| RefSeq | XP_001633129.1 | 0 | 29 | 372 | 6 | 355 | predicted protein [Nematostella vectensis] |
| RefSeq | XP_001691860.1 | 0 | 41 | 370 | 32 | 371 | hypothetical protein CHLREDRAFT_145451 [Chlamydomonas reinhardtii] |
| RefSeq | XP_417758.2 | 0 | 29 | 372 | 60 | 409 | PREDICTED: hypothetical protein [Gallus gallus] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4ad0_D | 0 | 35 | 360 | 44 | 361 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4ad0_C | 0 | 35 | 360 | 44 | 361 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4ad0_B | 0 | 35 | 360 | 44 | 361 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4ad0_A | 0 | 35 | 360 | 44 | 361 | A Chain A, Wif Domain-Epidermal Growth Factor (Egf)-Like Domains 1-3 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
| PDB | 4acz_A | 0 | 35 | 360 | 44 | 361 | A Chain A, Structure Of The Gh99 Endo-Alpha-Mannosidase From Bacteroides Thetaiotaomicron |
| Signal Peptide | |||||
|---|---|---|---|---|---|
| Cleavage Site | |||||
| 24 | |||||
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO627855 | 386 | 32 | 383 | 0 |
| EH669148 | 237 | 33 | 259 | 4.99983e-42 |
| GW595129 | 207 | 176 | 365 | 6e-40 |
| HO639020 | 145 | 32 | 174 | 8e-40 |
| HO434704 | 191 | 192 | 365 | 3e-32 |
| Orthologous Group | |||||
|---|---|---|---|---|---|
| Species | ID | ||||
| Chlamydomonas reinhardtii | Cre03.g189050.t1.3 | ||||
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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