Basic Information | |
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Species | Thellungiella halophila |
Cazyme ID | Thhalv10018308m |
Family | AA3 |
Protein Properties | Length: 601 Molecular Weight: 66156 Isoelectric Point: 10.3367 |
Chromosome | Chromosome/Scaffold: 9 Start: 3324982 End: 3328385 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 50 | 593 | 0 |
SSFASSSSSSFSSNGRDSSYDYIVIGGGTAGCPLAATLSRNFSVLVLERGGVPFTNANVSFLRNFHIGLADTSASSASQAFVSTDGVYNARARVLGGGSC INAGFYSRADAAFVKRAGWDPKLVKESYPWVEREIVHQPKLTLWQKALRDSLLEVGVRPFNGFTYDHVSGTKIGGTIFDRFGRRHTAAELLAYANPQKLR VLIYATVQKIVFDTSGARPKVTGVIFKDEKGNQHQALLSNRKGSEVILSSGAIGSPQMLMLSGIGPKRELQRLKIPLVLENEHVGKGMADNPMNTILVPS KQPIEQSLIQTVGITKMGVYVEASTGFGQSPESIHTRYGIMSDKNELFSTIPAKQRRPEATRGHISRNKYQLHEAFNGSFILEKLAYPISRGHLSLVNTN VDDNPSVTFNYFSHPVDLQRCVEAIRLVSKVVTSKRFLNYTQCDKQNVHKMLSLSVKANINLRPKQVNDTRSMAQFCKDTVVTIWHYHGGCLVGKVVSPD RKVLGVNRLRVIDGSTFDESPGTNPQATVMMMGRYMGVKILRER |
Full Sequence |
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Protein Sequence Length: 601 Download |
MFWFLQSPMA LKLFLFALLL CLPSSLSSTA SKGKEQKFNP YRYTFIDKAS SFASSSSSSF 60 SSNGRDSSYD YIVIGGGTAG CPLAATLSRN FSVLVLERGG VPFTNANVSF LRNFHIGLAD 120 TSASSASQAF VSTDGVYNAR ARVLGGGSCI NAGFYSRADA AFVKRAGWDP KLVKESYPWV 180 EREIVHQPKL TLWQKALRDS LLEVGVRPFN GFTYDHVSGT KIGGTIFDRF GRRHTAAELL 240 AYANPQKLRV LIYATVQKIV FDTSGARPKV TGVIFKDEKG NQHQALLSNR KGSEVILSSG 300 AIGSPQMLML SGIGPKRELQ RLKIPLVLEN EHVGKGMADN PMNTILVPSK QPIEQSLIQT 360 VGITKMGVYV EASTGFGQSP ESIHTRYGIM SDKNELFSTI PAKQRRPEAT RGHISRNKYQ 420 LHEAFNGSFI LEKLAYPISR GHLSLVNTNV DDNPSVTFNY FSHPVDLQRC VEAIRLVSKV 480 VTSKRFLNYT QCDKQNVHKM LSLSVKANIN LRPKQVNDTR SMAQFCKDTV VTIWHYHGGC 540 LVGKVVSPDR KVLGVNRLRV IDGSTFDESP GTNPQATVMM MGRYMGVKIL RERLGNKAGV 600 * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 3.0e-9 | 66 | 160 | 105 | + choline dehydrogenase; Validated | ||
PRK02106 | PRK02106 | 5.0e-32 | 225 | 590 | 388 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 1.0e-38 | 70 | 582 | 565 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 3.0e-47 | 65 | 593 | 585 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 32 | 600 | 569 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAA77842.1 | 0 | 23 | 600 | 15 | 594 | ACE [Arabidopsis thaliana] |
RefSeq | NP_001154469.1 | 0 | 23 | 600 | 15 | 567 | HTH (HOTHEAD); FAD binding / aldehyde-lyase/ mandelonitrile lyase [Arabidopsis thaliana] |
RefSeq | NP_565050.1 | 0 | 23 | 600 | 15 | 594 | HTH (HOTHEAD); FAD binding / aldehyde-lyase/ mandelonitrile lyase [Arabidopsis thaliana] |
RefSeq | XP_002329018.1 | 0 | 38 | 600 | 29 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 40 | 599 | 38 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 66 | 593 | 24 | 517 | A Chain A, Barley Alpha-Amylase Isozyme 1 (Amy1) H395a Mutant |
PDB | 3gdp_A | 0 | 66 | 593 | 24 | 517 | A Chain A, Barley Alpha-Amylase Isozyme 1 (Amy1) H395a Mutant |
PDB | 3gdn_B | 0 | 66 | 593 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 66 | 593 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 66 | 593 | 24 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |