Basic Information | |
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Species | Volvox carteri |
Cazyme ID | Vocar20002011m |
Family | GT47 |
Protein Properties | Length: 658 Molecular Weight: 74738.9 Isoelectric Point: 6.9641 |
Chromosome | Chromosome/Scaffold: 25 Start: 1078666 End: 1088191 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 250 | 604 | 0 |
KLKIYVYDLPERVSYRKPWHDEPALLDTMYLAELLFMEQLLGDWSVRTENPWEANLFVLPTYTIYYTGNIGFPAKHFANVFNYVRSNYPFWNLTGGRNHV AFATNDRGCCDLYKLARSNPELQHPIKVVHFSQTSDPALEAAFREFKRLAVHQTSGGAEGEAMEEDGGGTVMQELPEALVRFRGFPPYTLEALRMEREPC FRPEQDVAVPNYLERGWIGRLQEAYAYDREGNAVHRDKQRPYLFYFNGYSKPDMAYSGGVRQGLLSMYHNLTRGDVAINPGCCTAEYMLQSRFCLCPLGY GWGIRLTQAMQSGCVPVIVQDHTYSAFWDLLPYEKFSVRINRHNLHRLFDLLDAV |
Full Sequence |
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Protein Sequence Length: 658 Download |
MPRQHQILDT LFLLGLQFLV PTHAQIEPAI VANKPCPAGC TSHGNCNGET GLCECRFGFG 60 GPDCSTRLLP ACHSAPDLAT SIPGYGHLFP KNCYCLRQLV NSACPRSTFQ DPSQCPYFQF 120 WDWKETRCYV LKTLAAQEED PFQFVDFPPP EPYVLQNGDV LVGLERCPGR CSGRGWCVKK 180 GVEDTYTCRC HGFYEGEACE TPLNQHCYRN CSGRGTCSGG FCHCQPPYWG LGCTRSKAYV 240 AETWLPHPTK LKIYVYDLPE RVSYRKPWHD EPALLDTMYL AELLFMEQLL GDWSVRTENP 300 WEANLFVLPT YTIYYTGNIG FPAKHFANVF NYVRSNYPFW NLTGGRNHVA FATNDRGCCD 360 LYKLARSNPE LQHPIKVVHF SQTSDPALEA AFREFKRLAV HQTSGGAEGE AMEEDGGGTV 420 MQELPEALVR FRGFPPYTLE ALRMEREPCF RPEQDVAVPN YLERGWIGRL QEAYAYDREG 480 NAVHRDKQRP YLFYFNGYSK PDMAYSGGVR QGLLSMYHNL TRGDVAINPG CCTAEYMLQS 540 RFCLCPLGYG WGIRLTQAMQ SGCVPVIVQD HTYSAFWDLL PYEKFSVRIN RHNLHRLFDL 600 LDAVTPEQLK DLQKGLADYH RYFVWHTDAG GLAYNATLTS LHRRLLNMWT ALFRGSS* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-14 | 247 | 386 | 141 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
pfam03016 | Exostosin | 7.0e-24 | 444 | 604 | 168 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001694919.1 | 0 | 28 | 653 | 6 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694986.1 | 0 | 10 | 653 | 2 | 680 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694987.1 | 0 | 34 | 649 | 46 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001699824.1 | 0 | 33 | 651 | 37 | 728 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001699926.1 | 0 | 11 | 654 | 144 | 783 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |