Basic Information | |
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Species | Selaginella moellendorffii |
Cazyme ID | 107675 |
Family | GT47 |
Protein Properties | Length: 435 Molecular Weight: 50156.4 Isoelectric Point: 6.6353 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 60 | 369 | 0 |
RPLRIFMYDLPSKFTYGVVERYLRSRGIARNDKRLRYPGTQHSAEWWLFYDLEQGEDRRLSDASVRVMNPQEADVFYVPFFSSLSLVVGNGKSEDDEDPY SDEDIQEELMAWLEEQESWKKNKGRDHVVICQDPNALKRLRDRLKNTVLLLSDFERFKPDQASLVKDVVLPYTHRIDSYFNENVTLDRDTLLFFMGNRYR KEGGKIRDQLFQVLDVEPDMVMKHGTQSREGRRLAKVGMQTSKFCLHPAGDTPSACRLFDAIVSVCVPVIVSDDIELPFEDELDYSEFAIFVPSINALEP GYLGSYLRSI |
Full Sequence |
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Protein Sequence Length: 435 Download |
MRRGSIWAPT LLLLLAYLVL HGASNVFYFE SRAVVQSIGP AARHLKSSES LIALPVSESR 60 PLRIFMYDLP SKFTYGVVER YLRSRGIARN DKRLRYPGTQ HSAEWWLFYD LEQGEDRRLS 120 DASVRVMNPQ EADVFYVPFF SSLSLVVGNG KSEDDEDPYS DEDIQEELMA WLEEQESWKK 180 NKGRDHVVIC QDPNALKRLR DRLKNTVLLL SDFERFKPDQ ASLVKDVVLP YTHRIDSYFN 240 ENVTLDRDTL LFFMGNRYRK EGGKIRDQLF QVLDVEPDMV MKHGTQSREG RRLAKVGMQT 300 SKFCLHPAGD TPSACRLFDA IVSVCVPVIV SDDIELPFED ELDYSEFAIF VPSINALEPG 360 YLGSYLRSIS PDLLKQKQQR LREVRKYFEY EEKGGAVEMI WLEVKKKLPF IRTMINRDKR 420 LVERSSGNCS CICS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-69 | 60 | 369 | 321 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |