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Basic Information | |
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Species | Selaginella moellendorffii |
Cazyme ID | 171410 |
Family | GT20 |
Protein Properties | Length: 886 Molecular Weight: 98683.1 Isoelectric Point: 6.1382 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 78 | 547 | 0 |
EQRQRLLVVANRLPVSAIRRGENAWALELSAGGLVSALLGVKQFETTWIGWAGVNVQDDVGKESLSRALGEEGFVPVFLDEQTVDLYYNGYCNNVLWPLF HYIGLTQDDRLAATRGLEAQFNAYKRANSIFAQVVLSHYQKGDVVWCHDYHLMFLPRFLKEAKSEMKVGWFLHTPFPSSEIYRTLPQRSELLQAVLKADL IGFHTYDYARHFVSACTRILGLEGTPDGVEDQGKLTRVAAFPIGIDAERFVRALHTSTVRNHIQELSRRFSGRKVMLGVDRLDMIKGIPQKLLAFEKFLE DNPIWHDKVVMVQIAVPTRTDVHEYQKLSSQVHEIVGRINGRFGTLTTVPIHHLDRSLEFYELCALYAITDVLLVTSLRDGMNLVSYEYVACQDQKKGVL VLSEFAGAAQSLGAGAILINPWNIVEAACAIADALNMSETERQERHRHNFIHVTSHTAQLWADTFVSELN |
Full Sequence |
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Protein Sequence Length: 886 Download |
MYGSEEEEDD PVASQAGPLL GEEGYHDHSV SSSKLGSGSP VFSSRVGRLL RERQLRRGES 60 GAGDIDGIGG SEGIIKDEQR QRLLVVANRL PVSAIRRGEN AWALELSAGG LVSALLGVKQ 120 FETTWIGWAG VNVQDDVGKE SLSRALGEEG FVPVFLDEQT VDLYYNGYCN NVLWPLFHYI 180 GLTQDDRLAA TRGLEAQFNA YKRANSIFAQ VVLSHYQKGD VVWCHDYHLM FLPRFLKEAK 240 SEMKVGWFLH TPFPSSEIYR TLPQRSELLQ AVLKADLIGF HTYDYARHFV SACTRILGLE 300 GTPDGVEDQG KLTRVAAFPI GIDAERFVRA LHTSTVRNHI QELSRRFSGR KVMLGVDRLD 360 MIKGIPQKLL AFEKFLEDNP IWHDKVVMVQ IAVPTRTDVH EYQKLSSQVH EIVGRINGRF 420 GTLTTVPIHH LDRSLEFYEL CALYAITDVL LVTSLRDGMN LVSYEYVACQ DQKKGVLVLS 480 EFAGAAQSLG AGAILINPWN IVEAACAIAD ALNMSETERQ ERHRHNFIHV TSHTAQLWAD 540 TFVSELNDTV VEAELRILRV PPPLPVEKAI SSYATSKNCL LILGFNAALT AQADAPRLDR 600 VRETLHPALH ETLRHLCADP KATVVILSGS ERSLLDEAFG DFKLWLAAEN GMFLRHTSGD 660 WMTTMPEHLN LDWVESVQLV FDYFSERTPR SYVEARQTSL VWNFKYADLE FGRVQAWDML 720 QHLWTGPISN AAVDVVQGSK SVEVRPVGVS KGAAIDRILG EVVHSKNMSV PIDYVMCIGH 780 FLSKDEDIYT FFEPDLPYQR VNIEPKAASP PRSKAAPSTT KTARSRDHPI APQESSMIQG 840 ASVLDLNGEN YFSCTVGRQR SLARYSLTGS EEVVAFLSSL AKPSN* 900 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 80 | 885 | 839 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 79 | 881 | 806 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
pfam00982 | Glyco_transf_20 | 0 | 81 | 548 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
TIGR02400 | trehalose_OtsA | 0 | 82 | 548 | 468 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
PRK14501 | PRK14501 | 0 | 82 | 759 | 681 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 82 | 550 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 82 | 550 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 82 | 550 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 82 | 550 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 82 | 550 | 3 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
Sequence Alignments (This image is cropped. Click for full image.) |
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