Basic Information | |
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Species | Selaginella moellendorffii |
Cazyme ID | 229884 |
Family | GT47 |
Protein Properties | Length: 346 Molecular Weight: 39959.2 Isoelectric Point: 8.8717 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 288 | 0 |
RLFKVYVYKEGEPRLVHKGPLTGIYSSEGRFIHEMNQNSRFVTHDPQEAHMFFLPYSVAHMVLDLYVPGSHTMLPLATFIKDYVNLIASKHPFWNLTRGS DHFFTSCHDWGPATARDHPELRKNSVKVVCNSDLTEEFVPDKDASLPETYLHAVKLPTKLGGPGPSKRPILAFFAGQMHGRVRPALIKHWKDRGDPDMRI YEVLPPEVARRTSYVQHMKSSKFCICAMGFEVNSPRIVESIYYDCVPVLIADNFVLPFSDVLNWGSFSLTVSEKDVPRLKELLLAV |
Full Sequence |
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Protein Sequence Length: 346 Download |
MERLFKVYVY KEGEPRLVHK GPLTGIYSSE GRFIHEMNQN SRFVTHDPQE AHMFFLPYSV 60 AHMVLDLYVP GSHTMLPLAT FIKDYVNLIA SKHPFWNLTR GSDHFFTSCH DWGPATARDH 120 PELRKNSVKV VCNSDLTEEF VPDKDASLPE TYLHAVKLPT KLGGPGPSKR PILAFFAGQM 180 HGRVRPALIK HWKDRGDPDM RIYEVLPPEV ARRTSYVQHM KSSKFCICAM GFEVNSPRIV 240 ESIYYDCVPV LIADNFVLPF SDVLNWGSFS LTVSEKDVPR LKELLLAVSE DRYRKMQSRL 300 KKVRKHFLWH DSAERFDMFH MILHSVWTRR LQQMDAIIGH ETSMV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-63 | 1 | 288 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
Sequence Alignments (This image is cropped. Click for full image.) |
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