| Basic Information | |
|---|---|
| Species | Selaginella moellendorffii |
| Cazyme ID | 23945 |
| Family | GT47 |
| Protein Properties | Length: 305 Molecular Weight: 35124.9 Isoelectric Point: 7.6021 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 27 | 282 | 2.1e-31 |
| HNAPVRYFTKLNETRWHTKDPEKACIFMVFLDTSSPWQKQPRDLPHWNNGLNHALVTFADKWSQRAVAEESIGLASLIVSEAHETIFRPGFDISIPLPPF YHFHEFQNLKPFERKYFLTFKGLRYIGRGEGLLRSFDSFRNLHNGADIVVVTSCKHFVNDLKRKENSSLGVHCDEDENLYSQYSSFSDLMNTTFGLVPAG VQPNSYRFGEVLSAGAIPILIVDNYVKPFSNLATWYQCLLQFPSTEIHLIVAALRA | |||
| Full Sequence |
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| Protein Sequence Length: 305 Download |
| RCSMDACFNF SRCSNMDNLM VFTYEDHNAP VRYFTKLNET RWHTKDPEKA CIFMVFLDTS 60 SPWQKQPRDL PHWNNGLNHA LVTFADKWSQ RAVAEESIGL ASLIVSEAHE TIFRPGFDIS 120 IPLPPFYHFH EFQNLKPFER KYFLTFKGLR YIGRGEGLLR SFDSFRNLHN GADIVVVTSC 180 KHFVNDLKRK ENSSLGVHCD EDENLYSQYS SFSDLMNTTF GLVPAGVQPN SYRFGEVLSA 240 GAIPILIVDN YVKPFSNLAT WYQCLLQFPS TEIHLIVAAL RAMSTAHVEK RQHACSKIYS 300 RHFQS |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-25 | 31 | 283 | 276 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Hydropathy |
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| Orthologous Group | |||||
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| Species | ID | ||||
| Physcomitrella patens | Pp1s143_125V6.1 | Pp1s115_92V6.1 | Pp1s47_67V6.1 | Pp1s13_257V6.1 | Pp1s47_134V6.1 |
| Pp1s47_145V6.1 | Pp1s69_76V6.1 | Pp1s68_175V6.1 | Pp1s111_147V6.1 | ||
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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