| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 27985.m000889 |
| Family | GT47 |
| Protein Properties | Length: 453 Molecular Weight: 51973.9 Isoelectric Point: 9.4317 |
| Chromosome | Chromosome/Scaffold: 27985 Start: 341937 End: 345212 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 79 | 376 | 0 |
| SMKIYVYEEKEIDGLKELLRGRDGKISADTCVKGQWGTQVKIHRLLQNSRYRTRKKEEADLFFVPAYVKCVRMLGGLNDKEINLTYVKVLSQMPYFRRSG GRDHIFVFPSGAGAHLFRSWATYINRSVILTPEGDRTDKKDTSAFNTWKDIIIPGNVDDGMTKIGTTIVKPLPLSKRKFLANYLGRAQGKVGRLKLIELA KQYPDKLECPELKFSGPEKFGKMEYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDQAELPFQNVIDYTHVSIKWPSTKIGPELLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 453 Download |
| MGSSLNITNS RSRMLISHGQ CSRTHQIGAL LLIVSTFFLT RLVDQSFSTC TSYDVASQSQ 60 SHAQTLVHLI NGGYGTHPSM KIYVYEEKEI DGLKELLRGR DGKISADTCV KGQWGTQVKI 120 HRLLQNSRYR TRKKEEADLF FVPAYVKCVR MLGGLNDKEI NLTYVKVLSQ MPYFRRSGGR 180 DHIFVFPSGA GAHLFRSWAT YINRSVILTP EGDRTDKKDT SAFNTWKDII IPGNVDDGMT 240 KIGTTIVKPL PLSKRKFLAN YLGRAQGKVG RLKLIELAKQ YPDKLECPEL KFSGPEKFGK 300 MEYFEHLRNA KFCLAPRGES SWTLRFYESF FVECVPVLLS DQAELPFQNV IDYTHVSIKW 360 PSTKIGPELL EYLESIPDED IERMIANGRQ VRCLWVYAPE SEQCSAMQGI MWELQRKVRQ 420 FHQSTETFWL HNRTIVNRNM VEFSSWKPPM VLP |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-47 | 77 | 376 | 312 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 3 | 453 | 2 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 9 | 453 | 5 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 453 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 453 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 453 | 1 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| EV523405 | 267 | 1 | 267 | 0 |
| CX668832 | 291 | 140 | 430 | 0 |
| FE707914 | 279 | 120 | 398 | 0 |
| FE707913 | 273 | 181 | 453 | 0 |
| HO781282 | 318 | 21 | 337 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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