Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 28694.m000670 |
Family | AA3 |
Protein Properties | Length: 597 Molecular Weight: 65143.3 Isoelectric Point: 9.5743 |
Chromosome | Chromosome/Scaffold: 28694 Start: 87043 End: 91361 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 58 | 590 | 0 |
SSSGGDSAYDYIVVGGGTAGCPLAATLSQNFSVLLLERGGVPFTNSNVSFLNNFHITLADTSATSASQYFISTDGVLNARARVLGGGTSINAGFYTRAST RFIKKVGWDEKLVNESYPWVEKQIVHKPKVAPWQVTFRDSLLDVGVSPYNGFTYDHIYGTKFGGTIFDQFGRRHTAAELLASGNPRLLTVLVHATVQRVL FDTSRKHPKAVGVVFKDENGNQHQAFLANNPRSEIILSSGAIGTPQMLLLSGIGPKDELKKMGIPVVLDNEFVGKGMADNPMNTIFVPSKKPVRQSLIQT VGITKFGVYIESSSGFGQSKDSIHCHHGMMSAEIGQLSTIPPKKRTLEAIQAYIKRKKDLPHEAFKGGFILEKLASPISTGQLSLINTNVDDNPSVTFNY FKHPEDLRSCVNGVRMATKIVQSEHFTNFTQCDKQTMEKILNISVVANVNLIPKHPNDTKSIEQFCQDTVISIWHYHGGCHVGKVVSPDHKVLGVDRLRI VDGSTFDESPGTNPQATVLMMGRYMGLKILRDR |
Full Sequence |
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Protein Sequence Length: 597 Download |
MASFGAVKKN LSLYLLLLLY TLSSSQGNNA AGEPYSYPSH YPFIKKASSF SSSSSSYSSS 60 GGDSAYDYIV VGGGTAGCPL AATLSQNFSV LLLERGGVPF TNSNVSFLNN FHITLADTSA 120 TSASQYFIST DGVLNARARV LGGGTSINAG FYTRASTRFI KKVGWDEKLV NESYPWVEKQ 180 IVHKPKVAPW QVTFRDSLLD VGVSPYNGFT YDHIYGTKFG GTIFDQFGRR HTAAELLASG 240 NPRLLTVLVH ATVQRVLFDT SRKHPKAVGV VFKDENGNQH QAFLANNPRS EIILSSGAIG 300 TPQMLLLSGI GPKDELKKMG IPVVLDNEFV GKGMADNPMN TIFVPSKKPV RQSLIQTVGI 360 TKFGVYIESS SGFGQSKDSI HCHHGMMSAE IGQLSTIPPK KRTLEAIQAY IKRKKDLPHE 420 AFKGGFILEK LASPISTGQL SLINTNVDDN PSVTFNYFKH PEDLRSCVNG VRMATKIVQS 480 EHFTNFTQCD KQTMEKILNI SVVANVNLIP KHPNDTKSIE QFCQDTVISI WHYHGGCHVG 540 KVVSPDHKVL GVDRLRIVDG STFDESPGTN PQATVLMMGR YMGLKILRDR LGKEAGA 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 5.0e-23 | 434 | 579 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 2.0e-24 | 70 | 579 | 569 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 7.0e-29 | 70 | 579 | 561 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 7.0e-45 | 70 | 590 | 574 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 30 | 597 | 568 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI35951.1 | 0 | 37 | 596 | 35 | 592 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 36 | 596 | 25 | 583 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 56 | 596 | 7 | 546 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 20 | 596 | 18 | 590 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 1 | 597 | 1 | 597 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 63 | 590 | 24 | 517 | A Chain A, Recombinant Horseradish Peroxidase Phe209ser Complex With Benzhydroxamic Acid |
PDB | 3gdp_A | 0 | 63 | 590 | 24 | 517 | A Chain A, Recombinant Horseradish Peroxidase Phe209ser Complex With Benzhydroxamic Acid |
PDB | 3gdn_B | 0 | 63 | 590 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 63 | 590 | 24 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 63 | 590 | 24 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |