Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29002.m000149 |
Family | GT47 |
Protein Properties | Length: 535 Molecular Weight: 61592.1 Isoelectric Point: 7.0564 |
Chromosome | Chromosome/Scaffold: 29002 Start: 79099 End: 80944 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 102 | 448 | 0 |
CLGRYVYIHEIPSKFNQELLDNCESITRGTEHNMCPYLVNSGLGVEVENSQRVLLNKSWYSTNQFLLEVIFHNRMKKYECLTNDSSLASAIYVPFYAGLD VSRYLWGVKTSIRDQSAFDLMKWLVQRPEWKKMLGRDHFLIAGRIAWDFRRQTDNESDWGSKFRFLPESNNMSMLAIESSSWNNDYAIPYPTCFHPSKES EVSQWQDKMRNQTRPYLFSFAGAPRPDLQESVRGKIIEECQASKSLCKLLECDYGANGAINCDNPVNVMRLFQNSVYCLQPTGDSYTRRSIFDSILAGCI PVFFHPGTAYAQYKWHLPKNYSKYSVYIPVRDVKEWKAGINETLLRI |
Full Sequence |
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Protein Sequence Length: 535 Download |
MEKPITRICC NNQLWLVILV SFVFCFVLLC FDYSALTGTQ DSFTVLVNNY ENAVATQKSK 60 SLLLPNNVNE TTIRPNITGY IRKQPQPSRE ESVAENSVKD SCLGRYVYIH EIPSKFNQEL 120 LDNCESITRG TEHNMCPYLV NSGLGVEVEN SQRVLLNKSW YSTNQFLLEV IFHNRMKKYE 180 CLTNDSSLAS AIYVPFYAGL DVSRYLWGVK TSIRDQSAFD LMKWLVQRPE WKKMLGRDHF 240 LIAGRIAWDF RRQTDNESDW GSKFRFLPES NNMSMLAIES SSWNNDYAIP YPTCFHPSKE 300 SEVSQWQDKM RNQTRPYLFS FAGAPRPDLQ ESVRGKIIEE CQASKSLCKL LECDYGANGA 360 INCDNPVNVM RLFQNSVYCL QPTGDSYTRR SIFDSILAGC IPVFFHPGTA YAQYKWHLPK 420 NYSKYSVYIP VRDVKEWKAG INETLLRIPE DRVLAMREEV IKIIPSIIYA DPRSRMETTE 480 DAFDLAVKGI LERIERVTKV TKEGKDPSIG FADGDDYKYT FSGYLGETNS TKVYY 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-69 | 101 | 448 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |