| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 29589.m001240 |
| Family | GH29 |
| Protein Properties | Length: 562 Molecular Weight: 63653.2 Isoelectric Point: 6.883 |
| Chromosome | Chromosome/Scaffold: 29589 Start: 154181 End: 157200 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 68 | 363 | 0 |
| LQWQLTSMALFLHFGTNTFTDSEWGSGRADPSIFNPTQFNAAQWVQVAKDSGFSRLILTAKHHDGFCLWPSNYTDYSVKSSSWRNGTGDVVKELALAAKE AGIDLGFYLSPWDRHEASYGKSLEYNEYYMGQMTELLTRYGEIKEVWLDGAKGEGEKDMEYFFDRWFGLIRQLQPGAVIFSDAGPDTRWIGDENGAAGST CWSLFNRSAVKIGGADPKYSQRGDPSGHDWVPAECDVSIRPGWFWHASETPKSAMKLLEIYYNSAGRNCLLLLNVPPNASGLISAEDIQVLQEFAQ | |||
| Full Sequence |
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| Protein Sequence Length: 562 Download |
| MKEYEKKKKK MSIKNSNFGS KHQKPILNHI IPDKFLIFLS LSSISISCYA LQKPPPLPIL 60 PLPSAPQLQW QLTSMALFLH FGTNTFTDSE WGSGRADPSI FNPTQFNAAQ WVQVAKDSGF 120 SRLILTAKHH DGFCLWPSNY TDYSVKSSSW RNGTGDVVKE LALAAKEAGI DLGFYLSPWD 180 RHEASYGKSL EYNEYYMGQM TELLTRYGEI KEVWLDGAKG EGEKDMEYFF DRWFGLIRQL 240 QPGAVIFSDA GPDTRWIGDE NGAAGSTCWS LFNRSAVKIG GADPKYSQRG DPSGHDWVPA 300 ECDVSIRPGW FWHASETPKS AMKLLEIYYN SAGRNCLLLL NVPPNASGLI SAEDIQVLQE 360 FAQLRRSIFS YNIAKNKIAL LSASSTRGGN GNSQFDPYNV LKEGIYTYWA PEENQYNWEL 420 HLELQELVAF NVLQVQEPIH MGQRIIEFHV EILEDGEWKK VINGTTVGYQ RLLQFPTAVS 480 QHIKFVVDKS REDPLISYLG IYIDQFSIVS NKFGNNCSQT HSISSQVLRQ QNSKLNITIA 540 SMAVEYFSKL HKIILNLLQY NV |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 6.0e-35 | 101 | 361 | 285 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 2.0e-39 | 101 | 363 | 281 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 3.0e-64 | 70 | 502 | 447 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 53 | 507 | 28 | 482 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 53 | 507 | 28 | 482 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 64 | 511 | 51 | 493 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 50 | 507 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 1 | 562 | 1 | 562 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3mo4_B | 0 | 63 | 497 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 63 | 497 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 63 | 497 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 63 | 497 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3uet_B | 0 | 63 | 497 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DY270181 | 284 | 70 | 353 | 0 |
| DY291901 | 279 | 70 | 348 | 0 |
| DY300194 | 325 | 92 | 415 | 0 |
| FC905625 | 274 | 70 | 343 | 0 |
| DY300194 | 29 | 70 | 98 | 0.0000002 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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