y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29589.m001247 |
Family | GT47 |
Protein Properties | Length: 461 Molecular Weight: 53205.4 Isoelectric Point: 10.2431 |
Chromosome | Chromosome/Scaffold: 29589 Start: 194338 End: 196609 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 105 | 404 | 0 |
KDLKIYIYELPSKYNRDWLSNKRCSNHLFASEVAIHKAISNSDDIRTFDPYEADFFFVPVYVSCNFSTINGFPAIGHARSLLSSAVTFISTNYPFWNRSQ GADHVFVASHDFGSCFHTLEERAMQDGVPEFLKKSIILQTFGVKYDHPCQQVENVVIPPYISPVSVRSTLKKAPLTGRRDIWVFFRGKMEVHPKNVSGRF YSKKVRTEIWRRFNGDRRFYLQRHRFAGYQSEIARSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVPWPAISLTVAEKDVAKLGRILED |
Full Sequence |
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Protein Sequence Length: 461 Download |
MAELIKPTRK NRGFYVKMKL VHRNGRLQQQ QLEKSNLCFK YYKWVLWISL SLYFITSYFI 60 SHKPIPLSKA QYFSKSAVVS RALFESTNST FFHQPKNNTN QALLKDLKIY IYELPSKYNR 120 DWLSNKRCSN HLFASEVAIH KAISNSDDIR TFDPYEADFF FVPVYVSCNF STINGFPAIG 180 HARSLLSSAV TFISTNYPFW NRSQGADHVF VASHDFGSCF HTLEERAMQD GVPEFLKKSI 240 ILQTFGVKYD HPCQQVENVV IPPYISPVSV RSTLKKAPLT GRRDIWVFFR GKMEVHPKNV 300 SGRFYSKKVR TEIWRRFNGD RRFYLQRHRF AGYQSEIARS VFCLCPLGWA PWSPRLVESV 360 ALGCVPVIIA DGIRLPFPSA VPWPAISLTV AEKDVAKLGR ILEDVAATNL TLIQKNIWDP 420 TVRRALLFND QIEEGDATWQ VLYALTKKLD RSRRTVRVSS Q 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-68 | 105 | 402 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |