| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 29607.m000232 |
| Family | GT20 |
| Protein Properties | Length: 927 Molecular Weight: 104727 Isoelectric Point: 7.1455 |
| Chromosome | Chromosome/Scaffold: 29607 Start: 8907 End: 35633 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 88 | 556 | 0 |
| IRQRLLVVANRLPVSAVRRGEDSWSLEISAGGLVSALLGVKDFEARWIGWAGVNVPDEIGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFH YLGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNKHYEEGDVVWCHDYHLMFLPKCLKEYNSNMKVGWFLHTPFPSSEIHRTLPSRSELLHSVLAADLV GFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSERFIRALEVPQVQEHIKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLEE NSHWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQDSKKGVLI LSEFAGAAQSLGAGAILVNPWNITEVADSIRQALTMPREEREKRHRHNFEHVVGHNAQQWAETFVSELN | |||
| Full Sequence |
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| Protein Sequence Length: 927 Download |
| MPGNQYNGNS TPYSSRVQRL LREIELKKIY KASSHSSNEV TEPCEYDVRS REGDNSNNSY 60 IEQYLEGAVA ASRELPEGCE KNDGIKPIRQ RLLVVANRLP VSAVRRGEDS WSLEISAGGL 120 VSALLGVKDF EARWIGWAGV NVPDEIGQKA LTKALAEKRC IPVFLDEEIV HQYYNGYCNN 180 ILWPLFHYLG LPQEDRLATT RSFQSQFAAY KKANQMFADV VNKHYEEGDV VWCHDYHLMF 240 LPKCLKEYNS NMKVGWFLHT PFPSSEIHRT LPSRSELLHS VLAADLVGFH TYDYARHFVS 300 ACTRILGLEG TPEGVEDQGR LTRVAAFPIG IDSERFIRAL EVPQVQEHIK ELKERFAGRK 360 VMLGVDRLDM IKGIPQKILA FEKFLEENSH WRDKVVLLQI AVPTRTDVPE YQKLTSQVHE 420 IVGRINGRFG TLTAVPIHHL DRSLDFHALC ALYAVTDVAL VTSLRDGMNL VSYEFVACQD 480 SKKGVLILSE FAGAAQSLGA GAILVNPWNI TEVADSIRQA LTMPREEREK RHRHNFEHVV 540 GHNAQQWAET FVSELNDTVI EAQLRTRQVP PMLPEDDAIK RFLQSNNRLL ILGFNSTLTE 600 PVDTPGRRAD QIKEMELKLH PDLKDTLRAL CSDSKTTIVV LSGSGRGVLD ENFREFDMWL 660 AAEHGMFLRL TKGEWMTTMP EHLNMEWVDS VKHVFEYFKD RTPRSHLELR ETSLVWNYKY 720 ADVEFGRLQA RDMLQHLWTG PISNASVDVV QGSRSVEVRP VGVTKGAAID RILGEIVHSK 780 SVTTPIDYVL CIGHFLGKDE DVYTFFEPEL PSDGIGITRT KQTDGLKSPG ERRPSKLPAS 840 RTGSKPSQGK TSRPSPNSDK RNNNHSCGSV RRQSPEKISW NVLDLKGDNY FSCAVGRTRT 900 SARYLLQSPD DVVSFLRKLA IASSGTQ 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 0 | 1 | 927 | 935 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 83 | 926 | 844 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 0 | 91 | 793 | 710 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| TIGR02400 | trehalose_OtsA | 0 | 91 | 557 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABO61742.1 | 0 | 1 | 926 | 1 | 925 | trehalose-phosphate synthase 1 [Solanum lycopersicum] |
| RefSeq | NP_177979.1 | 0 | 1 | 924 | 1 | 940 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002285632.1 | 0 | 1 | 924 | 1 | 925 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002331300.1 | 0 | 1 | 924 | 1 | 922 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531237.1 | 0 | 1 | 927 | 1 | 927 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 91 | 559 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 91 | 559 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 91 | 559 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 91 | 559 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 91 | 567 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX546763 | 304 | 77 | 380 | 0 |
| ES813375 | 393 | 452 | 843 | 0 |
| CV711307 | 293 | 89 | 381 | 0 |
| DW069910 | 288 | 177 | 464 | 0 |
| CX545499 | 305 | 394 | 698 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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