y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29680.m001722 |
Family | GT8 |
Protein Properties | Length: 776 Molecular Weight: 87774.3 Isoelectric Point: 8.2958 |
Chromosome | Chromosome/Scaffold: 29680 Start: 432807 End: 438801 |
Description | plant glycogenin-like starch initiation protein 6 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 262 | 499 | 9.3e-41 |
SKRLQKTDKAYVTLLYGDEFLLGVRVLGKSIKDTGSKKDRVVLVSDGVSDYAMKLLEADGWIVEKITLLANPNQARPKRFWGVYTKLKIFNMTNYRKVVF LDADTIVVRSIEDLFKCGKFCANLKHSERFNSGVMVLEPSQSVFNDMMSKVNTLHSYTGGDQGFLNSYYPDFPNAHVFQPNLPQEDLDSRSIPAMERLST LYNADVGLYMLANKWMVNETELHVIHYTLGPLKPWDWW |
Full Sequence |
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Protein Sequence Length: 776 Download |
METLRGPQMT MCDGNNLVTE VVSDEESHLC LYVLLQDMLK VGDTVVGFEM EWGFKGCSSR 60 SNSGRYSSDH SVHSDKSEHH SRKVEHHIAL LTICTKLGCV LIRLSPNYIS PSLKRFFAIK 120 DIVFVGVHIK EDVQKLREDY GVVIRNAVEL SDWAAKVQDN PRFIFYSARE LANKILSVKF 180 EPKPYTVLWS NWFDHNLSPE QIECAASDAY AAYRIGKKLL DSGNKRVSVC FLVKIYGCLQ 240 FVVVKPFYIL AEVIVSVQSG DSKRLQKTDK AYVTLLYGDE FLLGVRVLGK SIKDTGSKKD 300 RVVLVSDGVS DYAMKLLEAD GWIVEKITLL ANPNQARPKR FWGVYTKLKI FNMTNYRKVV 360 FLDADTIVVR SIEDLFKCGK FCANLKHSER FNSGVMVLEP SQSVFNDMMS KVNTLHSYTG 420 GDQGFLNSYY PDFPNAHVFQ PNLPQEDLDS RSIPAMERLS TLYNADVGLY MLANKWMVNE 480 TELHVIHYTL GPLKPWDWWT SWLLKPVDVW QNVREQLEES LPGTGGGKNP NNELLVKFLF 540 ILPLVAVLFF YYRSFVQTRA FCRNSLFDHM RHFYYTIRSN GYAGVSSSST FNSANHFANG 600 AQSKVPAYLG GLSIFVCFMA ALMSIAFSLA IVPRQVMPWT GMLLMYEWTF TIFFVLFGGY 660 LHLAHLWGKM TATQVFISSN PESSDHESGK GHQRQGSLCD VGTWYYGLGM AFLAIATPSL 720 PCIFGITALF MRLGLVVAGG IVLASFMTYA SEHLAIRAFL KGFDDWDTTR ARSIRV 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN00176 | PLN00176 | 5.0e-14 | 252 | 496 | 290 | + galactinol synthase | ||
cd06914 | GT8_GNT1 | 5.0e-16 | 271 | 496 | 246 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
pfam01501 | Glyco_transf_8 | 2.0e-23 | 273 | 496 | 266 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd06141 | WRN_exo | 3.0e-27 | 39 | 220 | 183 | + DEDDy 3'-5' exonuclease domain of WRN and similar proteins. WRN is a unique RecQ DNA helicase exhibiting an exonuclease activity. It contains a DEDDy-type DnaQ-like 3'-5' exonuclease domain possessing three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. Mutations in the WRN gene cause Werner syndrome, an autosomal recessive disorder associated with premature aging and increased susceptibility to cancer and type II diabetes. WRN interacts with key proteins involved in DNA replication, recombination, and repair. It is believed to maintain genomic stability and life span by participating in DNA processes. WRN is stimulated by Ku70/80, an important regulator of genomic stability. | ||
cd02537 | GT8_Glycogenin | 9.0e-78 | 271 | 517 | 260 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
Gene Ontology | |
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GO Term | Description |
GO:0003676 | nucleic acid binding |
GO:0005622 | intracellular |
GO:0006139 | nucleobase-containing compound metabolic process |
GO:0008408 | 3'-5' exonuclease activity |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABZ89190.1 | 0 | 254 | 771 | 23 | 539 | hypothetical protein 46C02.16 [Coffea canephora] |
EMBL | CAN77613.1 | 0 | 247 | 776 | 8 | 510 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002266145.1 | 0 | 247 | 774 | 8 | 542 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319122.1 | 0 | 239 | 773 | 4 | 541 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522004.1 | 0 | 1 | 776 | 1 | 776 | glycogenin, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3u2x_B | 2e-22 | 268 | 498 | 3 | 223 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
PDB | 3u2x_A | 2e-22 | 268 | 498 | 3 | 223 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
PDB | 3u2v_B | 2e-22 | 268 | 498 | 3 | 223 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
PDB | 3u2v_A | 2e-22 | 268 | 498 | 3 | 223 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
PDB | 3u2u_B | 2e-22 | 268 | 498 | 3 | 223 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |