Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29717.m000231 |
Family | GT47 |
Protein Properties | Length: 478 Molecular Weight: 54462.6 Isoelectric Point: 8.872 |
Chromosome | Chromosome/Scaffold: 29717 Start: 63334 End: 66111 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 52 | 403 | 0 |
KDSIKVYLADLPRSFNYGLLDQYWSTSKPDTRISSDPDHHPQRGPVHLQKTSKFPPYPESPLIKQYSAEYWIMGDLMTPENLRSQSFAKRVFDFNQADVV FVPFFATLSAEMELARGEGTFRKKEGNEDYKRQKEVIEFVKSSDAWKRSGGKDHVFVLTDPVAMWHVRAEIAPAVLLVVDFGGWYRLDSKSSDGNSSNII RHTQVSLLKDVIVPYTHLLPQLPLSENKKRQTLLYFKGAKYRHRGGMVREKLWDLLVNEPGVIMEEGFPNATGREQSIKGMRTSEFCLHPAGDTPTSCRL FDAIQSLCIPIIVSDNIELPFEGIVDYLEFSVFMAVDDALKPNWLVDHLKSI |
Full Sequence |
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Protein Sequence Length: 478 Download |
MPPKNIHLQC SIPSLFLTFI SISLFFSLLW LLLSSPKNLS FPDPQNNRQP SKDSIKVYLA 60 DLPRSFNYGL LDQYWSTSKP DTRISSDPDH HPQRGPVHLQ KTSKFPPYPE SPLIKQYSAE 120 YWIMGDLMTP ENLRSQSFAK RVFDFNQADV VFVPFFATLS AEMELARGEG TFRKKEGNED 180 YKRQKEVIEF VKSSDAWKRS GGKDHVFVLT DPVAMWHVRA EIAPAVLLVV DFGGWYRLDS 240 KSSDGNSSNI IRHTQVSLLK DVIVPYTHLL PQLPLSENKK RQTLLYFKGA KYRHRGGMVR 300 EKLWDLLVNE PGVIMEEGFP NATGREQSIK GMRTSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PIIVSDNIEL PFEGIVDYLE FSVFMAVDDA LKPNWLVDHL KSISKKQRDE FRQKMAEVQS 420 IFEYDNGYAG GIGPVPPNGA VNHIWKKVHQ KLPIIKEAIV REKRKPAGVS IPLRCHCT 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-59 | 51 | 403 | 365 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |