y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29742.m001446 |
Family | GH18 |
Protein Properties | Length: 938 Molecular Weight: 104030 Isoelectric Point: 8.5717 |
Chromosome | Chromosome/Scaffold: 29742 Start: 529418 End: 542803 |
Description | Glycosyl hydrolase superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH18 | 190 | 423 | 1.4e-31 |
DYVIELLVSECKEMEYDGIVLESWSRWQGYLILHDLKTRKKALQFIKQLADALHSVSSTRNIKQHLQLIYVIGPPHSEKFQPYDFGPQDLQSLSDAVDGF SLMTYDFSSPNNPGPNAPLKWIHHVLQLLLGASSNGARAPAYKIFLGISFYGNDFHFSKGSGGGAIVGRDYLSLLEKHKPKLQWEKNSGEHFFLYVDDED TKHLVFYPSLMSLSLRLDEARLWGTGVSIWEIGQ |
Full Sequence |
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Protein Sequence Length: 938 Download |
MAKTRNRRVT QGSDSTEKRV GRTQAQVNEP ADSAASNRKL IAVFVFFFIV IPAASVLVYH 60 IKCPSNTNNT RRQQSLIQAD VNYQDILTEH SKVSKNASHR EFTHPVLAYV TPWNAKGYEM 120 AKRFTNKFTH LSPVWYDLKS KGSELILEGR HNADRGWLSE IRKNGDALVL PRVVLEAFPM 180 EMLIKKNVTD YVIELLVSEC KEMEYDGIVL ESWSRWQGYL ILHDLKTRKK ALQFIKQLAD 240 ALHSVSSTRN IKQHLQLIYV IGPPHSEKFQ PYDFGPQDLQ SLSDAVDGFS LMTYDFSSPN 300 NPGPNAPLKW IHHVLQLLLG ASSNGARAPA YKIFLGISFY GNDFHFSKGS GGGAIVGRDY 360 LSLLEKHKPK LQWEKNSGEH FFLYVDDEDT KHLVFYPSLM SLSLRLDEAR LWGTGVSIWE 420 IGQGLDYFFD LLPLNFHYSL VWKCTVPGDD FRFVNMQMKW SLNLLIHNFF VFMVIMKSVF 480 DRQIVWCPVL LFCTVEYLVF LTKNYAMEAL NAAGLTPISV LCEKRNEPRK IWCPPTSPLK 540 FSGSAPLSTT SLSLQDCLSR SYSGSLVVLS SVLSTGLAKA LTYEEALQQS AGTAASESDA 600 SGVLDNVISF ATENPVVIAG GAVVLAVPLI LSQILKKPKS WGVESAKKAY ALLGDDANAQ 660 LLDIRAPVEL RKVGTPDIRG FKKKPVPISY NGEDKTGFLK RLSLKFKEPE NTTLFILDKY 720 DGNSELVAEL VTVNGFKAAY AIKDGAEGPK GWTNSSLPWI PPSKTLSFDL SSLTDAFSIG 780 VCAFPIHSFY CKVFTFDGGF FSLLQIETIL QVLGSAAIIQ FASKKLLYAE ERKQTLKQVD 840 EFLNTKIAPK ELADEIKQIG KALLPSTTTN KALPPPAEAS SEPAAAENTV QKAEAVAEPA 900 PQINSAKAGS VSGFSRPLSP YASYPDLKPP TSPTPSQP 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam00704 | Glyco_hydro_18 | 1.0e-11 | 233 | 423 | 211 | + Glycosyl hydrolases family 18. | ||
COG3858 | COG3858 | 3.0e-20 | 192 | 436 | 250 | + Predicted glycosyl hydrolase [General function prediction only] | ||
cd02874 | GH18_CFLE_spore_hydrolase | 4.0e-26 | 106 | 432 | 349 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
smart00636 | Glyco_18 | 8.0e-28 | 106 | 423 | 351 | + Glyco_18 domain. | ||
cd02876 | GH18_SI-CLP | 6.0e-143 | 102 | 432 | 336 | + Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAB61039.1 | 0 | 67 | 877 | 91 | 853 | A_IG002N01.31 gene product [Arabidopsis thaliana] |
EMBL | CBI40499.1 | 0 | 1 | 432 | 1 | 435 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_192013.1 | 0 | 67 | 432 | 65 | 430 | glycosyl hydrolase family 18 protein [Arabidopsis thaliana] |
RefSeq | XP_002320856.1 | 0 | 72 | 432 | 40 | 399 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523373.1 | 0 | 1 | 928 | 1 | 928 | chitinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3bxw_A | 0 | 72 | 432 | 46 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
PDB | 3bxw_B | 0 | 72 | 432 | 46 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
PDB | 2dcq_A | 0 | 646 | 765 | 9 | 128 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
PDB | 1vee_A | 0 | 646 | 765 | 9 | 128 | A Chain A, Nmr Structure Of The Hypothetical Rhodanese Domain At4g01050 From Arabidopsis Thaliana |
PDB | 3cz8_B | 0.000001 | 272 | 421 | 166 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |