Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29815.m000494 |
Family | GT47 |
Protein Properties | Length: 574 Molecular Weight: 65277.9 Isoelectric Point: 8.3701 |
Chromosome | Chromosome/Scaffold: 29815 Start: 42463 End: 45889 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 237 | 518 | 0 |
EKQFKVFVYEEGEPPVFHNGPCKSIYSMEGNFIHRMEIDDQFRTKDPEKAHVYFLPFSVAMMVQFVYVRDSHDFGPIKRTVRDYVNLVAGKYPYWNRSLG ADHFMLACHDWGPETSFSLPDLAKNSIRALCNANTSERFNPIKDVSFPEINLQTGTTKGFIGGPSPSKRSILAFFAGGLHGPIRPILLEHWENKDNDMKV HRYLPKGVSYYEMMRKSKFCLCPSGYEVASPRVVEALYTGCVPVLISDHYVPPFSDVLNWKSFSVEVPVSDIPNLKRILTSI |
Full Sequence |
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Protein Sequence Length: 574 Download |
MGINDEDHCC YGSRKGYHAW RFPTSSMKLL LFMVPLIVVS GFIAVLGPKF STNLEFLSTH 60 SWLVKYGASL NSSLPVVSHA KLQSERVVRV QDLHPAVVVM EEAEAAVDTA DRKVLISNEA 120 SSPATLDVQA IDIQQLIWLI LLGIIESLIS TNATGENDKQ ISSNRSSIAA WPNDSSIKTT 180 HQKAFTNLER LEAGLQNARA AIKEAKNGNQ TEDPEYVPIG PMYWNSKVFH RSYLEMEKQF 240 KVFVYEEGEP PVFHNGPCKS IYSMEGNFIH RMEIDDQFRT KDPEKAHVYF LPFSVAMMVQ 300 FVYVRDSHDF GPIKRTVRDY VNLVAGKYPY WNRSLGADHF MLACHDWGPE TSFSLPDLAK 360 NSIRALCNAN TSERFNPIKD VSFPEINLQT GTTKGFIGGP SPSKRSILAF FAGGLHGPIR 420 PILLEHWENK DNDMKVHRYL PKGVSYYEMM RKSKFCLCPS GYEVASPRVV EALYTGCVPV 480 LISDHYVPPF SDVLNWKSFS VEVPVSDIPN LKRILTSISS RQYIRMQRRV LQVRRHFEVN 540 SPPKRYDVFH MILHSIWLRR LNVKIHDDQL SITS |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-65 | 236 | 518 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 157 | 567 | 3 | 407 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 140 | 567 | 83 | 517 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 236 | 566 | 1 | 331 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 236 | 563 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 1 | 574 | 1 | 574 | catalytic, putative [Ricinus communis] |